Unogara wakaneta here? Izvi zvinogona kunge zviri dambudziko ne pituitary gland yako here? (Hypopituitarism)

Dzimwe nguva unonzwa sekuti muviri wako hauna simba, sekunge pane chimwe chinhu chiri kushaikwa here? Pamwe chikonzero cheizvi idambudziko diki mune rimwe remagland madiki, asi akakosha kwazvo mumuviri wako. Nhasi tichataura nezve hypopituitarism , chirwere chisingawanzoitika mugland yepituitary . Usanetseke, tichataura nezvazvo zviri nyore, nenzira yaunogona kunzwisisa.

Chii chinonzi hypopituitarism?

Zvichitaurwa zviri nyore, hypopituitarism inoitika kana pituitary gland yako isingagadzi mahormone akakwana. Iye zvino ungangove uchishamisika kuti mahormone aya chii. Mahormone akafanana nemakemikari anotumira mameseji ekuti miviri yedu ishande zvakanaka. Mahormone epituitary anodzora zvinhu zvakawanda, kusanganisira metabolism yedu, kukura kwemuviri, kukura pabonde, uye kubereka.

Funga nezvazvo senzvimbo diki yekuraira mumuviri wedu, pituitary gland. Asi hazvishande zvega. Zvinobatsirwa nechimwe chikamu chakakosha cheuropi chinonzi hypothalamus . Hypothalamus inoudza pituitary gland kuti, "Zvakanaka, buritsa hormone izvozvi." Hypothalamus inodzorawo zvinhu zvakaita seBP, kurova kwemoyo, tembiricha yemuviri, uye kugaya. Saka, kana paine kukuvara kana chirwere kune pituitary gland kana hypothalamus, unogona kutanga hypopituitarism.

Dambudziko iri rinogona kuitika kamwe kamwe, kunyangwe mushure metsaona. Kana kuti rinogona kukura zvishoma nezvishoma kwemwedzi kana makore. Kazhinji, vanhu ava vanofanira kutora mishonga kweupenyu hwavo hwese kuti vadzore zviratidzo zvavo. Asi musazvidya mwoyo, chiremba wenyu achakutarisisai zvakanyanya uye achakupai kurapwa kwakakodzera.

Kune mhando dzakasiyana dze hypopituitarism here?

Ehe, inogona kukamurwa kuita mhando mbiri huru. Imwe inobva pakuti mahormone akawanda sei ari kushaikwa .

• Kushaikwa kwepituitary: Muizvi, hormone imwe chete yepituitary ndiyo inoshaikwa.
• Kushomeka kwemahormone epituitary akawanda: Apa ndipo panenge paine kushomeka kwemahormone maviri kana kupfuura epituitary.
• Panhypopituitarism: Ichi chirwere chisina kunyanya kuipa apo mahormone ese anogadzirwa nepituitary gland anodzikira.

Tevere, dzinoiswa muzvikamu zvichienderana nechikonzero uye kuti pituitary gland inokanganiswa sei :

• Kushaya simba kwemuviri (primary hypopituitarism): Izvi zvinokonzerwa nekukuvara kana chirwere chinokanganisa zvakananga gland repituitary.
• Hypopituitarism yechipiri: Izvi zvinokonzerwa nekukuvara kana chirwere chehypothalamus. Yeuka, hypothalamus ndiyo inopa mirairo kugland repituitary.
• Idiopathic hypopituitarism: Dzimwe nguva chikonzero hachiwanikwe.

Ndezvipi zviratidzo zveHypopituitarism?

Zviratidzo zvinosiyana zvichienderana nehomoni isina kukwana . Zvinhu zvinotevera zvine chekuitawo nazvo:

• Murume/Mukadzi wako.
• Zera rako rakatanga dambudziko iri .
• Chikonzero che hypopituitarism.
• Mahormone akadzikira nekukurumidza sei .

Iye zvino ngationei kuti zviratidzo zvipi zvinoonekwa kana hormone imwe neimwe yaderera.

Zviratidzo zveKushaikwa kweHormone Yekukura (GH)

Kune vacheche vachangoberekwa:

• Kuderera kweshuga muropa (Hypoglycemia) .
• Kuva nenhengo yemurume diki zvisina kujairika (Micropenis) .

Kune vana vadiki:

• Kukura kunonoka kana kuti hakumboitiki zvachose. Semuenzaniso, kana mwana wako achiita seasingakure zvakanyanya zvichienzaniswa nevamwe vana vezera rake, izvi zvinogona kuva chiratidzo cheizvi.
• Kureba kupfupi .
• Kunonoka kana kusavapo kwekukura pabonde panguva yekuyaruka.

Kune vakuru:

• Kugara kuneta zvakanyanya . Kunzwa sekunge bhatiri rapera.
• Kunzwa kusafara uye kugutsikana nehupenyu.
• Kuderera kwemabasa epabonde uye chishuwo .
• Kuwedzera kwemafuta, kunyanya muchiuno .
• Kusakwanisa kushivirira kutonhora nekupisa .
• Kudzikira kwehuremu hwetsandanyama .
• Kudzikira kwesimba nekutsungirira pakuita maekisesaizi.

Zviratidzo zvekushaikwa kweThyroid-Stimulating Hormone (TSH)

Kune vacheche vachangoberekwa:

• Kuderera kwetsinga dzemuviri (makumbo nemakumbo zvinonzwa sezvisina hupenyu).
• Kupisa muviri kwakaderera (Hypothermia) .
• Kunzwa kuzvimba .
• Kuchema nenzwi rakashoshoma, risina chinhu .

Kune vana vadiki nevakuru:

Zviratidzo zveizvi zvakafanana nezve hypothyroidism , nekuti hormone yeTSH inokurudzira thyroid gland kuti igadzire mahormone ayo.

• Kuneta kwakanyanya .
• Ganda rakaoma uye bvudzi rinopera simba .
• Kuzvimba kwemuviri .
• Kuwedzera uremu .
• Kushaya simba kwetsandanyama .
• Kusakwanisa kushivirira dzihwa .
• Matambudziko epfungwa akadai sekuora mwoyo .
• Vakadzi vanogona kuenda kumwedzi zvisina kurongeka kana kubuda ropa rakawanda kupfuura zvakajairika .

Zviratidzo zveFollicle-Stimulating Hormone (FSH) uye/kana Luteinizing Hormone (LH) kushomeka

FSH neLH mahormone anonzi gonadotropins . Izvi zvinokanganisa zvakananga hurongwa hwedu hwekubereka .

Kune vakomana vacheche:

• Kuva nenhengo yemurume diki zvisina kujairika (Micropenis) .
• Machende asina kudzika .

Kune vana vadiki:

• Kusakura kwemazamu kuvasikana.
• Machende evakomana haakure .
• Muviri hauone kuwedzera kwehurefu kamwe kamwe (kukura nekukurumidza) panguva yekuyaruka.

Kune varume:

• Kudzikira kwechido chebonde .
• Kuneta kwakanyanya .
• Kusabereka .
• Kusashanda zvakanaka kwenhengo dzesikarudzi .
• Kurasikirwa nebvudzi rechiso kana remuviri .

Kune vakadzi:

• Kuda kuita zvepabonde kwakaderera .
• Kuneta kwakanyanya .
• Kusabereka .
• Kupisa - Kunzwa kamwe kamwe kwekupisa mumuviri.
• Kuenda kumwedzi kusingaenderane nenguva kana kuti kurega kuenda kumwedzi zvachose (Amenorrhea) .
• Kurasikirwa nebvudzi mudumbu repazasi .
• Kutadza kugadzira mukaka wemuzamu mushure mekubereka mwana .

Zviratidzo zveAdrenocorticotropic Hormone (ACTH kana Corticotropin) Kushaikwa

Kune vacheche vachangoberekwa:

• Kuderera kweshuga muropa (Hypoglycemia) .
• Kurema kunowedzera zvishoma nezvishoma (Kutadza kukura zvakanaka) . Zvinoita sekuti mwana haasi kunyamwira kunyangwe ari kunwa mukaka wakakwana.
• Kubatwa nepfungwa dzakaipa .
• Kutsvuka kweganda (Jaundice) .

Kune vana vadiki nevakuru:

• Kuneta kwakanyanya .
• Kuderedza uremu pasina chikonzero .
• Kuderera kweropa (Hypotension) .
• Kusvotwa nekurutsa .
• Kuderera kweshuga muropa (Hypoglycemia) .
• Kuvhiringidzika, kurasikirwa nepfungwa .

Zviratidzo zvekushomeka kweProlactin

Chinhu chikuru chinoita kuti izvi zviitike ndechekuti mukaka wemuzamu haugadzirwe mushure mekubereka mwana .

Zviratidzo zveKushomeka kweOxytocin

• Matambudziko ekuyamwisa mwana mushure mekuzvarwa.
• Kuoma kubatana nemwana mushure mekuzvarwa.
• Kusanzwira tsitsi vamwe vanotambura.
• Kuoma kutaurirana nevamwe.

Zviratidzo zveAntidiuretic Hormone (ADH kana Vasopressin kana Arginine Vasopressin) Kushaikwa

Kune vacheche vachangoberekwa:

• Kurutsa .
• Fivha dzisingazivikanwi chikonzero .
• Kuchema zvakanyanya .
• Kuderedza huremu .
• Kuzvimba kwemuviri .
• Kunyorovesa manapukeni kakawanda (Manapukeni akanyorova zvikuru) .

Kune vana vadiki:

• Kuoma pakudzidzisa chimbuzi .
• Kunyorova pamubhedha .
• Kukurumidza kuneta .

Kune vakuru:

• Kuita weti kakawanda .
• Nyota yakawandisa .
• Kusawirirana kwema electrolyte .

Zvakakosha: Usazvidya mwoyo kana uine chimwe kana zviviri zvezviratidzo izvi, asi kana zvikaramba zviripo, zvakanaka kutsvaga rubatsiro rwechiremba.

Ndezvipi zvinokonzera hypopituitarism?

Panogona kuva nezvikonzero zvakawanda zvechirwere ichi. Dzimwe nguva kunyange vanachiremba havagone kutsanangura chikonzero chaicho. Kazhinji, chinogona kukonzerwa nezvinhu zvikuru zvitatu:

1. Kudzvanya pituitary gland kana hypothalamus.

2. Kukuvadzwa kwegland repituitary kana hypothalamus.

3. Kuva nechirwere chisingawanzoitiki kana chimwe chirwere chinokonzera hypopituitarism.

Mamiriro ezvinhu anokanganisa pituitary gland kana hypothalamus

Zvirwere zvinogona kukonzera kushushikana kweuropi muzvikamu izvi zvinosanganisira:

• Matumbu epituitary: Aya mabundu asina njodzi anoumbwa mugland repituitary. Anogona kushandura magadzirirwo anoitwa mahormone.
• Mabundu emuuropi: Mabundu anokura pedyo nehypothalamus kana pituitary gland anogona kukanganisa kugadzirwa kwemahormone.
• Lymphocytic hypophysitis (LH): Ichi chirwere chisingawanzoitiki. Pano, masero anonzi lymphocytes anopinda mugland repituitary. (Iyi LH haifanirwe kuvhiringidzwa neLuteinizing Hormone yambotaurwa, handiti?!)
• Sarcoidosis yepituitary kana hypothalamus: Sarcoidosis chirwere chinokonzera kuzvimba.

Zviitiko zvinokuvadza pituitary gland kana hypothalamus

• Kuvhiyiwa: Matambudziko panguva yekuvhiyiwa kweuropi (kunyanya kuvhiyiwa kubvisa pituitary adenomas).
• Kurapa nemwaranzi: Kurapa nemwaranzi kwaishandiswa kurapa kenza yekare kana kuti pituitary adenomas.
• Kukuvara kwakakomba mumusoro (Kukuvara kweuropi kwakakomba - TBI):Zvinhu zvakaita setsaona dzemotokari, kudonha, uye kukuvara mumitambo.
• Pituitary apoplexy: Kuparara kamwe kamwe kwenyama yepituitary gland.

Zvirwere zvisingawanzoitiki

• Kuora kweropa kweropa: Ichi chirwere chinokonzerwa nemajini. Chinokonzera iron yakawanda muropa. Izvi zvinogona kukuvadza pituitary gland.
• Meningitis yebhakitiriya: Kunyangwe isingawanzoitiki, hypopituitarism inogona kuitika sedambudziko remeningitis yebhakitiriya.
• Kuchinja kwemajini: Zvimwe zvirwere zvisingawanzoitiki zvemajini zvinogona kukonzera kushomeka kwemahormone epituitary.

Ndezvipi zvinhu zvinokonzera njodzi?

Mamiriro ezvinhu kana zviitiko zvinotevera zvinogona kuva zvinhu zvinokonzera hypopituitarism:

• Ndakamborapwa kenza uye nemwaranzi kare.
• Kukuvara kwemusoro kana uropi: Pakati pe27% ne32% yevanhu vakakuvara musoro (TBI) vanotanga kuora mwoyo.
• Chirwere ichi chinogona kukonzera kushomeka kwemahormone epituitary.
• Chirwere cheshuga cherudzi rwekutanga: Kukuvadzwa kwetsinga netsinga dzeropa kunokonzerwa nechirwere cheshuga cherudzi rwekutanga chisingadzoreki kunogona kukonzera chirwere ichi.
• Kubata pamuviri uye kusununguka: Kubuda ropa rakawanda mushure mekusununguka kunogona kukuvadza pituitary gland. Dambudziko iri rinonzi Sheehan syndrome .

Matambudziko anogona kuitika

Kushaikwa kwemahormone anokonzerwa ne hypopituitarism kunogona kukonzera kukura kwemamwe matambudziko. Izvi zvinosiyana zvichienderana nehomoni isina kukwana. Heano mimwe mienzaniso:

• Kushaikwa kweGH (growth hormone) kunogona kukonzera kufuta , cholesterol yakakwira , uye metabolic syndrome .
• Kushaikwa kwemahormone eestrogen (nekuda kwekushaikwa kweFSH) kunogona kukonzera osteoporosis ( kutetepa kwemapfupa) kuvakadzi.
• Kushaikwa kweACTH kunogona kukonzera dambudziko readrenal , dambudziko rinotyisidzira hupenyu.

Ndedzipi bvunzo dzinoitwa kuti chirwere ichi chionekwe?

Chiremba wako anogona kuraira chero ipi yeiyi bvunzo kuti aongorore hypopituitarism:

• Kuongororwa kweropa kwemazinga emahormone: Zvichienderana nezviratidzo zvako, chiremba wako anogona kuraira kuongororwa kweropa kunoyera mazinga akasiyana emahormone.
• Kuongororwa kwekusimudzira mahormone: Mukuedzwa uku, chiremba wako achakupa mushonga wekukurudzira pituitary gland yako kuti ibudise mahormone ari kuongororwa. Zvadaro, ropa rinotorwa roendeswa kurabhoritari kuti riongororwe.
• Kuongororwa kwekushivirira insulin: Izvi zvinogona kuona kushomeka kwehomoni yekukura (GH) uye ACTH.
• Kuongororwa kweropa neweti neOsmolality: Izvi zvinoongororwa kuti pane kushomeka kweADH (antidiuretic hormone).
• MRI (Magnetic Resonance Imaging) Scan: MRI scans inotora mifananidzo yakadzama yemukati memuviri wako. MRI scans yeuropi inoonekwa senzira yakanakisisa yekuwana bundu repituitary rinokonzera hypopituitarism.
• Kuongororwa kweBrain CT (Computed Tomography): Kuongororwa uku kunogona kushandiswa kuona kana paine bundu remuuropi kana pituitary adenoma iri kukonzera chirwere ichi.

Hypopituitarism inorapwa sei?

Kunyange hazvo pasina mushonga, unogona kurapwa . Kurapwa kunoenderana nekuti mahormone api asina kukwana uye chii chiri kukonzera chirwere chako . Chikwata chako chekurapa chichakubatsira kugadzira hurongwa hwekurapa hwakakunakira. Sarudzo dzakawanda dzekurapa dzinosanganisira:

• Kurapa kwekutsiva mahormone: Chinangwa cheizvi ndechekudzosera kudzikira kwemahormone epituitary kusvika padanho rakajairika. Kazhinji, mishonga inofanira kutorwa kweupenyu hwako hwese.
• Kuvhiyiwa: Vanhu vane pituitary adenomas vangada kuvhiyiwa kuti vabviswe.
• Kurapa nemwaranzi: Kurapa nemwaranzi kunogona kubatsira kuderedza pituitary adenomas.

Chiremba wako anogonawo kukurudzira kuti ugare uine kadhi reID rekurapa kana bracelet nguva dzese, kana paine dambudziko.

Chii chinonzi fungidziro ye hypopituitarism?

Maonero acho akasiyana-siyana, zvichienderana nezvinhu zvinotevera:

• Zera rako apo zviratidzo zvako zvakatanga .
• Chikonzero chemamiriro ako ezvinhu .
• Kuderera kwemahormone kunokonzerwa nei.
• Maitirwo emuviri wako kana warapwa .

Vanhu vazhinji vane hypopituitarism vanorarama hupenyu hune hutano. Zvisinei, kana paine kukuvara kwenguva refu kwepituitary, hupenyu hunogona kupfupika zvishoma pane hwemunhu wezera rimwe chete asina chirwere ichi. Zvisinei, hupenyu hunotarisirwa hauwanzo deredzwa kune avo vanotevera chirongwa chakakodzera chekurapa .

Ko kana paine emergency? Kana hypopituitarism ikangoerekana yaitika, ikanyanya, uye ikasarapwa, inogona kunge iri emergency yekurapa uye inotokonzera rufu. Saka kana ukaona zviratidzo, enda kuna chiremba nekukasika.

Ndinofanira kuona chiremba rini?

Kazhinji, hypopituitarism inoda kuti munhu anyatso tarisa mahormone akakanganiswa nechirwere ichi kweupenyu hwake hwese . Enda kuna chiremba wako nguva nenguva kuti uve nechokwadi chekuti chirongwa chako chekurapa chiri kushanda.Kana uine zviratidzo zvitsva kana zvinokunetsa, taura nachiremba wako nekukurumidza.

Mibvunzo ipi yandinofanira kubvunza chiremba wangu?

Kana ukaonekwa uine hypopituitarism, ungada kubvunza chiremba wako mibvunzo iyi:

• Ndivana rudzii rwehypopituitarism?
• Ndeapi mahormone ari pasi mandiri?
• Chikonzero cheizvi chii?
• Ndedzipi nzira dzekurapa dzandinadzo?
• Pane mimwe migumisiro yakaipa here kubva mukurapwa kwangu?
• Ndinofanira kutora mushonga kwenguva yakareba sei?
• Izvi zvichakanganisa here kubereka kwangu?
• Izvi zvichakanganisa here pamuviri pangu?
• Izvi zvingaitikawo kuvana vangu here?

Pakupedzisira, yeuka (Mharidzo Yekuenda Kumba)

Kuongororwa kutsva kunogona kutyisa, asi usatya kubvunza chiremba wako mibvunzo nezve hypopituitarism. Kazhinji, kurapwa kwehupenyu hwese uye kuongororwa kwemahormone zvinodiwa. Ndosaka zvichikosha kuona chiremba wako nguva dzose. Kana uine zviratidzo zvitsva kana zvinonetsa, taura nachiremba wako. Varipo kuti vakubatsire. Nekurapwa kwakakodzera, unogona kurarama hupenyu hune hutano uye hunoshanda.

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