Une gout here? Kana kuti pane mumwe munhu waunoziva ane chirwere ichi here? Saka pamwe unoziva kurwadziwa kwakanyanya kwemajoini. Saka, mumwe wemishonga inokurudzirwa navanachiremba yekudzivirira gout kwenguva refu iProbenecid. Muchinyorwa chino, tichataura nezvepiritsi iri reProbenecid, zvinoitika naro, uye zvinhu zvekungwarira paunenge uchiritora.
Chii chaizvo chinoitika nemushonga uyu weProbenecid?
Muchidimbu, mushonga uyu unonzi Probenecid unoshanda nekukurumidzisa kubuda kweuric acid yakawandisa mumuviri wedu kuburikidza neweti. Sezvamunoziva, gout inoitika kana huwandu hweuric acid mumuviri hukawedzera uye hunoiswa mumajoini semakristaro. Saka, nekuderedza huwandu hweuric acid, mushonga uyu unogona kudzivirira kudzoka kwekurwadziwa kwegout .
Mushonga uyu une rimwe basa zvakare. Unobatsira mamwe maantibiotic, akadai sepenicillin, kuti agare mumuviri kwenguva yakareba, zvichiita kuti mushonga uyu ushande zvakanaka.
Zvinhu zvekuudza chiremba wako usati watora mushonga
Usati watanga kushandisa Probenecid, zvakakosha kupa chiremba wako tsananguro yakazara yehutano hwako. Iva nechokwadi chekuvaudza nezvechero chezvirwere zvinotevera zvaunazvo:
- Kana uri kurwara negout panguva ino: Mushonga uyu unoshandiswa kudzivirira marwadzo kuti asauye, kwete kuderedza kana avapo. Saka, hautangi panguva iyoyo.
- Kana uine chirwere cheropa kana matambudziko eropa .
- Kana uine chirwere cheitsvo kana matombo eitsvo : Sezvo mushonga uyu uchishanda kuburikidza neitsvo, kana uine chero dambudziko reitsvo, chiremba wako anofanira kuziva nezvazvo.
- Kana uchangobva kugamuchira kurapwa nemwaranzi.
- Kana uine maronda mudumbu .
- Kana uine allergy nekuda kweprobenecid, mishonga yesulfa, kana chero imwe mishonga, chikafu, kana dhayi.
- Kana uine pamuviri kana kuti uri kuedza kubata pamuviri.
- Kana uri amai vari kuyamwisa.
Zvichibva paruzivo urwu, chiremba wako achasarudza kana mushonga uyu wakakunakira iwe kana kuti kana muyero wacho uchifanirwa kuchinjwa.
Mushonga uyu unoshandiswa sei chaizvo?
Nzira yekushandisa izvi iri nyore kwazvo, asi inokosha zvikuru.
- Piritsi iri rine girazi guru remvuraInwa. Zvakakoshawo kunwa mvura yakawanda mukati mezuva.
- Inwa mushonga chaiwo, sezvakarairwa nachiremba wako. Inwa mushonga wako panguva dzakatarwa, usingadarike nguva yekusangana.
- Usarega kutora mushonga kusvika chiremba wako akuudza kuti udaro. Ramba uchitora mushonga uyu kunyangwe uchinzwa zviri nani.
- Kana ikapihwa vana: Mushonga uyu hauwanzopihwa vana vari pasi pemakore maviri ekuberekwa. Kana uchipihwa vana vakura kupfuura ipapo, taura nachiremba wevana nezvazvo uye tevera mirairo yake.
- Kutora mushonga wepamusoro: Kana uchifunga kuti watora mushonga unopfuura wakatarwa, fonera National Poisons Information Centre kuColombo National Hospital nekukasika . Kana kuti enda kuEmergency Treatment Unit (ETU) yechipatara chiri pedyo.
Mushonga uyu ndewako chete. Usape mumwe munhu ane zviratidzo zvakafanana nezvako. Mushonga wakakodzera munhu wega wega ungasiyana.
Mimwe mishonga inogona kushanda pamwe chete nemushonga uyu
Probenecid inogona kushanda pamwe chete nemimwe mishonga. Saka udza chiremba wako nezvemishonga yese yaunotora, kunyangwe mavhitamini. Tafura iri pazasi ichatsanangura izvi zvakajeka.
| Kudyidzana kunogona kuitika neProbenecid | |
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| Mishonga isingafanirwe kutorwa pamwe chete | |
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| Mishonga inofanira kushandiswa nokungwarira uye kuudzwa chiremba | |
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Rondedzero iyi haina kukwana. Saka udza chiremba wako nezvemishonga yese yaunotora, kana uchisvuta, kana kana uchinwa doro.
Zvinhu zvakakosha zvaunofanira kuziva paunenge uchitora Probenecid
- Zvinotora nguva kuti uone mhedzisiro: Zvinogona kutora mwedzi yakati wandei kuti uone mhedzisiro yakazara yemushonga uyu. Saka, ungave uine marwadzo egout kana kuti kwete, ramba uchitora mushonga chero bedzi chiremba wako akuudza. Kana ukanzwa marwadzo akangoerekana aitika, chiremba wako achakupa mushonga wakasiyana weizvozvo.
- Chenjerera nemishonga inoderedza marwadzo:
- Doro harina kunwiwa: Doro rinogona kukanganisa kushanda kwemushonga uyu. Saka, dzivisa kunwa doro.
- Inwa mvura yakawanda: Zvakakosha kunwa magirazi emvura angangoita 8-10 pazuva kuti ubvise uric acid mumuviri uye kudzivirira matombo muitsvo. Usazvirega uchishaya mvura mumuviri.
- Mhedzisiro pane mimwe miedzo: Mushonga uyu unogona kukanganisa mhedzisiro yeimwe bvunzo dzinoongorora shuga muweti. Kana uri kuedzwa saizvozvo, udza chiremba wako pachine nguva.
- Kutsamwiswa kweganda, kuvaviwa, mapundu (Allergic reactions)
- Kuzvimba kwechiso, miromo, kana rurimi
- Kuoma kufema
- Fivha, dzihwa, zviratidzo zvehutachiona
- Ropa muweti
- Marwadzo mudumbu repazasi kana pahudyu (anokonzerwa neitsvo)
- Marwadzo kana kuoma kuita weti
- Kuzvimba uye kurwadziwa kwemajoini
- Kubuda ropa kusingawanzoitiki kana mavanga
- Kuneta kusingawanzoitiki kana kuneta
- Dzungu
- Kushambadza
- Kuita weti kakawanda
- Kudonha kwebvudzi
- Musoro
- Kuda kudya
- Kusvotwa, kurutsa
- Kurwadziwa kwemazino
- Probenecid mushonga unoshandiswa kudzora gout kwenguva refu, kwete kurwisa kurwiswa kamwe kamwe.
- Paunenge uchitora mushonga uyu, zvakakosha kunwa mvura yakawanda zuva rese.
- Usatore aspirin kana mimwe mishonga inoderedza marwadzo (kunyanya NSAIDs) usina kubvunza chiremba wako.
- Ipa chiremba wako tsananguro yakazara yemimwe mishonga yese, mavhitamini, uye zvimwe zvinovaka muviri zvauri kutora.
- Kana ukasangana nemigumisiro yakaipa (semuenzaniso mapundu eganda, kufema zvakaoma, kurwadziwa kwakanyanya), tsvaga rubatsiro rwechiremba nekukasika.
Mishonga yeNSAID inoderedza marwadzo yakaita seaspirin neibuprofen inogona kuderedza kushanda kwemushonga uyu. Saka, usatore mishonga yekuderedza marwadzo inotengwa nechiremba kana uchitora mamwe marwadzo. Bvunza chiremba wako usati watora chero mushonga wekurwadziwa.
Ndezvipi zvingakonzera migumisiro yakaipa?
Kufanana nemushonga upi zvawo, Probenecid inogona kukonzera migumisiro yakaipa kune vamwe vanhu. Mimwe yacho yakakomba, nepo mimwe isina kunyanyisa.
| Migumisiro yakakomba inofanira kutaurwa kuna chiremba wako nekukasika | |
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| Migumisiro isingawanzova yakakomba, asi inofanira kutaurwa kuna chiremba kana ikaramba iripo | |
Mharidzo Yekuenda Nayo Kumba
👩🏽⚕️ Mibvunzo yekuwedzera (Mibvunzo Inowanzo bvunzwa)
💬 Mapiritsi eProbenecid anoshandiswa pai?
Uyu mushonga unoshanda uye une simba pachirwere chearthritis chinonzi 'Gout' (Uricosuric agent)! Varwere vane gout vanotambura nekurwadziwa kusingatsungiririki uye kuzvimba nekuda kwemakristaro e'Uric Acid' anonamira semajekiseni mukati memajoini. Chinoitwa nepiritsi iri kubvisa uric acid yese ine njodzi mumuviri nekuibvisa.
💬 Kana mushonga uyu (Probenecid) ukapinda mumuviri, unobvisa sei 'uric acid' inokonzera marwadzo egout?
Kazhinji, mushure mekunge muviri wedu waburitsa uric acid kuburikidza neitsvo ichipinda muweti, itsvo dzinodzosa imwe yacho mumuviri/muropa (Reabsorption/URAT1). Zvinoitwa nepiritsi iri (Probenecid) zvinovhara zvachose 'reabsorption factory'. Sezvo risingakwanise kunyudzwa, uric acid yese iri muropa rako inobuda mumuviri wako serwizi (Excretion) pasina chipingamupinyi.
💬 Sei uchifanira kunwa mvura yakawanda paunenge uchinwa mapiritsi aya? Ndezvipi njodzi dziripo?
Piritsi iri rinosundira uric acid yese mumuviri ichipinda muitsvo/weti, saka kana usinganwe 'marita maviri kusvika matatu emvura pazuva', uric acid iyoyo inoungana muitsvo yogadzira 'matombo (matombo eitsvo eUric acid)'. Izvozvo zvinouraya! Chimwe chinhu chakakosha ndechekuti kana ukatora mushonga unouraya mabhakitiriya (senge Penicillin) paunenge uchitora piritsi iri, izvi zvinogona kuwedzera huwandu hwemushonga unoramba uri mumuviri (kusvika pakuva chepfu) uye kuwedzera migumisiro yemushonga (Kudyidzana kwemishonga).
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