Tose tinonzwa dzungu kana kuti musoro wakaneta pane imwe nguva patinomuka pachigaro kana pamubhedha. Kazhinji, zvinopera mumasekonzi mashoma. Asi kana izvi zvikaitika kakawanda, kana kuti ukanzwa sekunge wava kuda kupera simba wodonha, zvingasava zvakajairika. Nhasi tichataura nezvechirwere chisingawanzoitiki chinokonzera zviratidzo izvi. Izvozvo zvinonzi Pure Autonomic Failure, kana kuti PAF muchidimbu.
Zvichitaurwa zviri nyore, chii chinonzi Pure Autonomic Failure (PAF)?
Funga nezvazvo, kune maitiro akawanda mumuviri wedu anoitika ega tisingazvidzore. Semuenzaniso, kufema, kurova kwemoyo, kugaya chikafu, kudzora tembiricha yemuviri, uye kudzora BP. Zvese izvi zvinodzorwa neAutonomic Nervous System yedu. Zvakafanana ne'auto-pilot' system iri mumuviri wedu.
Kukundikana Kwemuviri Kusina Kunaka (PAF) chirwere chisingawanzoitiki chetsinga chinoderedza kushanda kwetsinga dzemuviri dzinozvidzora nekufamba kwenguva. Chinhu chikuru chinoitika munyaya iyi ndechekuti paunomira kamwe kamwe kubva panzvimbo yawakagara kana kuti wakarara, BP yako inoderera zvakanyanya . Mukurapa, tinodana izvi kuti orthostatic hypotension . Asi iri harisi iro dambudziko rega, PAF inogona kukonzera mamwe matambudziko akawanda.
Dambudziko iri rinowanzoonekwa kakawanda muvanhu vakuru vane makore ari pakati pe40 ne60. Kare, chirwere ichi chainziwo Bradbury-Eggleston syndrome.
Ndezvipi zviratidzo zvechirwere chePAF?
Sezvatakambokurukura, chiratidzo chikuru chinowanzoonekwa idzungu uye kufenda kana wamira (orthostatic hypotension). Zvisinei, sezvo iyi autonomic nervous system ichitonga nhengo dzakawanda mumuviri wedu, zviratidzo hazvigumiri pane chimwe chete.
Chinhu chakakosha ndechekuti zviratidzo izvi hazviitike nenzira imwe chete kana kuti nenzira imwe chete kune munhu wese. Vamwe vanhu vanogona kusangana nezvimwe zviratidzo vasati vanzwa dzungu pavanomira.
Ngationei zvimwe zviratidzo zvinogona kukonzerwa nePAF.
| Sisitimu/maitiro akanganiswa | Zviratidzo zvinogona kuitika |
|---|---|
| Kudikitira kwemuviri | Kazhinji pane kudzikira kwedikita (anhidrosis) kana dzimwe nguva kudikitira kwakanyanya (hyperhidrosis). |
| Kuona maziso | Kuona zvisina kujeka nekuda kwekuti vana vechikoro vakanga vasina kukura zvakakwana. |
| Sisitimu yeweti | Kuoma kubvisa tsvina yese mudundira (kuchengetwa kweweti) kana kutadza kudzora weti (kusadzora weti). |
| Sisitimu yekugaya chikafu | Kuzvimba kana kusazvidzora tsvina. |
| Kuita zvepabonde | Matambudziko akadai sekusashanda zvakanaka kwenhengo dzekubereka kana kuti anorgasmia. |
Pamusoro pezvo, inenge hafu yevanhu vane PAF vanogonawo kuva neanemia isina kunyanya kuipa.
Chii chakaita kuti PAF iumbwe?
Chikonzero chikuru cheizvi chakaonekwa sekuunganidza kusingawanzoitiki kwepuroteni inonzi alpha-synuclein mumasero edu etsinga anozvimiririra. Kufanana netsvina inovhara pombi, kana puroteni iyi ikaungana mumasero etsinga, mashandiro ayo anokanganiswa.
Puroteni iyi inoiswa mutsinga dzetsinga (autonomic ganglia) kumativi ese emusana kana pedyo nenhengo. Nekufamba kwenguva, huwandu hwemasero aya etsinga hunoderera, uye basa rehurongwa hwe autonomic rinokanganiswa. Asi chinonyanya kukosha ndechekuti muPAF, uropi kana musana hazvikuvadzi . Saka, hazvikanganisi zvinhu zvakaita sekurangarira nekukwanisa kufunga.
Vaongorori havasati vanyatsonzwisisa kuti sei puroteni iyi ichiiswa mumasero aya.
Kubatana nezvimwe zvirwere
Heino chimwe chinhu chakakosha kuziva. Puroteni iyi, alpha-synuclein, ndiyo inoungana muuropi muzvirwere zvakaita seParkinson's disease, Multiple System Atrophy, uye Lewy Body Dementia. Saka, vamwe vanhu vane PAF (vasiri vese) vane mukana wekuva nechimwe chezvirwere izvi nekufamba kwenguva. Chiremba wako achakuzivisa nezveizvi.
Nzira yekuziva sei chirwere ichi?
Kuongororwa kwePAF inzira yakaoma, sezvo vanachiremba vachitanga vabvisa zvimwe zvirwere zvinogona kukonzera zviratidzo zvako, kunyanya kudzikira kweBP paunomira.
Maitiro ekuongorora chirwere ichi anogona kusanganisira:
- Kubvunza mibvunzo nokungwarira nezvezviratidzo zvako uye nhoroondo yezvekurapa.
- Kuongororwa kwemuviri kwakakwana uye kuongororwa kwetsinga.
Mushure meizvozvo, bvunzo dzinoverengeka dzakakosha dzinogona kukurudzirwa kusimbisa chirwere.
| Bvunzo | Ingoita izvi chete... |
|---|---|
| Kuedzwa kweTafura Yakanamirwa | Uchaiswa pamubhedha wakasarudzika wobva wangoerekana wamira. Kumanikidzwa kweropa rako nekurova kwemoyo wako zvichatariswa. |
| bvunzo yedikita (QSART) | Izvi zvinotarisa mashandiro anoita tsinga dzinodzora kudikitira. Izvi zvinobatsira kuona matambudziko ane autonomic nervous system. |
| Miedzo yekufungidzira (yakadai seMRI) | Zvinhu zvakaita seMRI yeuropi zvinoitwa kuti pave nechokwadi chekuti hapana zvimwe zvirwere zvinogona kukonzera zviratidzo. |
| Kuongororwa kweLabhoritari (Ropa neWeti) | Huwandu hwekemikari inonzi norepinephrine muropa nemuweti hunoyerwa panguva yekurara pasi uye mushure mekumira. MuPAF, pane shanduko huru muhuwandu uhwu. |
Zvinogona kunetsa kuita bvunzo dzakawanda kudaro, asi kana tikaongorora chirwere nemazvo ndipo patinogona kugadzira hurongwa hwakanakisisa hwekurapa.
Ndezvipi zvinorapwa zvePAF?
Hapana mushonga weizvi parizvino. Asi usazvidya moyo. Pane zvinhu zvakawanda zvaunogona kuita kuti ubatsire kudzora zviratidzo zvako uye kurarama hupenyu hwakajairika. Chiremba wako nechikwata chekurapa vachashanda newe kugadzira hurongwa hwekurapa hwakanangana newe.
Kudzora BP yakaderera kana wakamira (Orthostatic Hypotension)
Iri ndiro dambudziko guru. Kune mishonga isiri yemishonga pamwe nemishonga yekurapa izvi.
- Chenjerera paunenge uchichinja nzvimbo: Paunosimuka kubva panzvimbo yawakarara kana kugara, zviite zvishoma nezvishoma . Usamuka kamwe kamwe.
- Mvura nemunyu: Chiremba wako anogona kukurudzira kunwa marita matatu emvura pazuva. Anogonawo kukuudza kuti uwedzere munyu mushoma muchikafu chako.
- Kugadzirira mubhedha: Rara musoro wemubhedha wakasimudzwa masendimita angangoita 1.5 kusvika ku1.5. Nenzira iyi, hauzonzwi musiyano mukuru muBP paunomuka.
- Mbatya Dzekudzvanya: Kupfeka masokisi akasimba (mbatya dzekudzvanya) anosvika muchiuno kana muzvidya kunobatsira kuderedza kuungana kweropa mumakumbo uye kuchengetedza BP yakasimba.
- Pamusoro peizvi, chiremba anokurudzirawo mishonga chaiyo inowedzera BP.
Matambudziko ekubvisa tsvina uye weti
- Pakuvimbiwa: Unogona kudya chikafu chine fiber yakawanda (muriwo, michero, mupunga webran) uye kushandisa zvinopfavisa tsvina.
- Kana uchinetseka nekuita weti: Kana uchinetseka nekuita weti, ungangoda kushandisa catheter. Kana usingakwanise kudzora weti yako, kune mishonga yakakosha (yakadai seOxybutynin, Mirabegron).
Unzenza hwepabonde
Kunyangwe paine mishonga yakaita se sildenafil kana tadalafil yeizvi, mishonga iyi inogona kuwedzera njodzi yekushomeka kweropa mumuviri. Saka, unofanira kukurukura izvi pachena nachiremba wako uye shandisa izvi chete kana achinge akupa zano.
Chii chichaitika mune ramangwana kumunhu ane chirwere ichi?
Zvakaoma kupa mhinduro imwe chete nezveramangwana remunhu anorarama nechirwere ichi, nekuti chinosiyana kubva pamunhu kusvika pamunhu.
PAF chirwere chinoramba chichienderera mberi. Asi kune vanhu vazhinji, chinoitika zvishoma nezvishoma, kwemakore, kunyange makumi emakore. Dzimwe ongororo dzakaratidza kuti avhareji yehupenyu hunotarisirwa mushure mekuonekwa uine PAF imakore angangoita 12.5. Asi iyi ingori avhareji, uye inogona kusiyana zvakanyanya zvichienderana nezviratidzo zvako nehutano hwako. Saka usanyanya kunetseka nenhamba idzodzo.
Kana uine PAF, zvakakosha kuti ugare uchiona chiremba wako kuti uve nechokwadi chekuti kurapwa kwako kuri kushanda uye kuti mamiriro ako ari kufambira mberi sei. Kana ukava nezviratidzo zvechirwere cheParkinson (zvakadai sekubvunda, kunetseka kufamba), unofanira kuudza chiremba wako nekukasika.
Mharidzo Yekuenda Nayo Kumba
- Kukundikana Kwekuzvigadzirisa Kwemuviri (PAF) chirwere chisingawanzoitiki chinokanganisa tsinga dzinodzora mashandiro emuviri wedu.
- Chiratidzo chikuru idzungu uye kupera simba kana uchimuka kubva panzvimbo yawakagara kana kuti wakarara nekuda kwekuderera kweBP.
- Kunyange hazvo chirwere ichi chisingarapiki zvachose, zviratidzo zvacho zvinogona kudzorwa zvakanaka uye hupenyu hwepamusoro hunogona kuchengetedzwa.
- Hapana nzira yekudzivirira izvi, uye haisi mhosva yako kuti zvakaitika.
- Zvakakosha kugara uchitaura nachiremba wako uye kutevedzera hurongwa hwako hwekurapa nemazvo. Usatya kutaura pachena nezvemibvunzo yako nezvinokunetsa.
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