Spravato (Esketamine) - Mushonga mutsva wekuderedza kushungurudzika usina kurapwa nemishonga!

Kuora mwoyo hakusi kungonzwa kusuruvara chete, asi chirwere chinoda kurapwa. Dzimwe nguva, kunyangwe mushure mekushandisa mishonga yakasiyana-siyana yekuora mwoyo, kuora mwoyo kwevamwe vanhu hakugadzirisike. Tinoti rudzi urwu rwechirwere kunoramba kurapwa. Nhasi, tiri kutaura nezvenzira yemazuva ano yekurapa inogona kubatsira vanhu vakadaro neavo vanotambura nekuora mwoyo kwakanyanya nepfungwa dzekuzviuraya.

Chii chinonzi Spravato? Inoshanda sei?

Spravato mushonga wekupfapfaidza mumhino une mushonga we esketamine . Mushonga uyu wakatenderwa neUS FDA muna 2019.

Pamwe wakambonzwa zita rekuti ketamine . Ketamine mushonga unopihwa netsinga (IV) semushonga wekurwadziwa uye wekurwadziwa muzvipatara. Unoshandiswawo mumakiriniki emhuka. Pamwe wakambonzwa zita iri nekuti vamwe vanhu vanorishandisa zvisirizvo kuti vanzwe kudhakwa uye vachiona zvinhu zvisipo.

Spravato imhando yakakosha yeketamine. Muchidimbu, mushonga uyu unoshanda pamareceptor ari muuropi hwedu anonzi N-methyl D-aspartate (NMDA) receptors . Kuburikidza neizvi, unogona kuderedza zviratidzo zvekuora mwoyo nekuchinja makemikari anobatanidzwa mumanzwiro edu.

Wakaziva sei kuti mushonga uyu unoshanda sei?

Zvidzidzo zvina zvekiriniki zvakaitwa kuti zviongororwe kuchengetedzeka uye kushanda kweSpravato. Zvidzidzo izvi zvinosanganisira vanhu vakuru vane makore ari pakati pe18 ne64.

Vakashandisa nzira yakakosha yekuongorora zviratidzo kuti vaone kuoma kwekuora mwoyo uye kuvandudzika kwezviratidzo. Inonzi Montgomery-Asberg Depression Rating Scale (MADRS) . Imibvunzo ine mibvunzo gumi. Inobvunza nezvezvinhu zvakaita semanzwiro, kunzwa mhosva, maitiro ekurara, uye kufunga kuzviuraya. Zvibodzwa zvacho zvinobva pa0 kusvika pa60, uye mamakisi akakwira achiratidza kuora mwoyo kwakanyanya . Mushure mekurapwa, mamakisi eMADRS paanonyanya kuipa, mamakisi akaderera, zvichiratidza kuvandudzika kwezviratidzo.

Ndezvipi zvakabuda muzvidzidzo izvi?

Zvakabuda izvi zvinoratidza kuti vanhu vakashandisa Spravato vakaderera zvakanyanya muzviratidzo zvekuora mwoyo. Zvidzidzo zvakawanawo kuti avo vakaramba vachishandisa Spravato vakanonoka kudzoka kwezviratidzo.

Chinoshamisa panyaya iyi ndechekuti Spravato inoratidza kudzikira kukuru kwezviratidzo mukati memaawa makumi maviri nemana mushure mekuishandisa . Mishonga inowanzo shandiswa yekudzora kushungurudzika inotora mavhiki akati wandei kuti iratidze mhedzisiro. Saka, izvi zvinogona kukosha zvikuru panguva yekukurumidzira.

Spravato inogona here kupindirana nemimwe mishonga?

Ehe, unofanira kungwarira nemimwe mishonga paunenge uchitora Spravato.

• Mishonga yeBP: Spravato inogona kuwedzera BP kwenguva pfupi. Njodzi iyi inowedzera kana uri kutora imwe mhando yemishonga inorwisa kushushikana kwepfungwa, yakaita se monoamine oxidase inhibitor (MAOI) , kana mishonga inosimudzira pfungwa. Saka, kana uri kutora mishonga iyi, unofanira kuongororwa BP yako nguva nenguva.
• Mishonga inokonzera hope nedzungu: Spravato inogona kukonzera hope nedzungu. Migumisiro iyi inogona kuwedzera kana ukashandisa mishonga inodzvinyirira tsinga dzemuviri, dzakadai se benzodiazepines (semuenzaniso, alprazolam, clonazepam), opioids (mishonga inouraya marwadzo), uye doro .

Ndingawana sei mushonga weSpravato?

Uyu hausi mushonga waunogona kutenga ku pharmacy woenda nawo kumba kuti ushandise.

Nekuda kwemigumisiro yakaipa uye njodzi yekushandisa Spravato zvisina kunaka, kurapwa uku kunogona kungoitwa panzvimbo dzakanyoreswa . Nzvimbo idzi dzinofanirwa kunyoreswa pasi pechirongwa chakakosha chinonzi Spravato REMS (Risk Evaluation and Mitigation Strategy).

1. Taura nachiremba wako: Kana uchifarira kurapwa uku, taura nachiremba wemhuri yako kana chiremba wepfungwa.

2. Kutumirwa Kwechiremba: Kana chiremba wako achifunga kuti Spravato yakakunakira, achakutumira kunzvimbo yekurapwa ine certification.

3. Kubvunzana: Uchabva wapihwa mazano panzvimbo yekurapwa. Ikoko, vanachiremba vachaongororawo mamiriro ako uye vozosarudza kana izvi zvakakunakira.

4. Kutanga kurapwa: Kana zvese zvakanaka, kurapwa kunogona kutanga pakushanya kwako kwechipiri.

Unoshandisa sei Spravato?

Izvi zvinotorwa kamwe chete kana kaviri pasvondo, panzvimbo ine certification, pasi pekutarisirwa kwevashandi vezvehutano .

• Chipimo uye mashandisirwo: Chiremba wako ndiye achasarudza chiyero chaunoda. Vachakudzidzisawo mashandisirwo emushonga wemumhino.
• Chikafu nemvura: Sezvo mushonga wacho uchigona kukonzera kuda kurutsa nekurutsa, zvinokurudzirwa kuti usadye maawa maviri usati warapwa uye usanwe mvura maminitsi makumi matatu usati warapwa .
• Nguva yekucherechedza:Mushure mekunwa Spravato, muchatariswa nachiremba wenyu kwemaawa maviri kuti vaone kana paine shanduko muropa renyu uye zvimwe zvinokanganisa.
• Kutyaira: Mushonga uyu unogona kukanganisa pfungwa dzako uye kugona kwako kuita sarudzo pazuva rekurapwa. Saka, unofanira kuronga kuti mumwe munhu akuendese kumba nemotokari kubva kunzvimbo yekurapwa . Zvakanaka kutyaira kana kuita mamwe mabasa anoda kungwarira zuva rinotevera mushure mekurara zvakanaka husiku.

Ndezvipi migumisiro yakaipa uye ingadziviswa sei?

Spravato inogona kuva nemigumisiro yakaipa, ndosaka ichingopihwa chete pasi pekutarisirwa nachiremba.

• Kurara uye kuvhiringidzika: Kurara zvakanyanya, dzungu, kupera simba, uye kupatsanurwa zvinogona kuitika.
• Kuoma kufema: Kufema kunogona kunonoka kana kudzika. Izvi zvinonyanya kuitika kana uine mamwe matambudziko ekufema kana kuti uri kutora mimwe mishonga inononoka kufema kwako.
• Kuwedzera kweropa: Kumanikidzwa kweropa kunogona kuwedzera kwenguva pfupi kwemaawa mana mushure mekutora mushonga. Kana uchinzwa kurwadziwa muchipfuva, kunetseka kufema, musoro wakakomba, kuchinja kwekuona, kana pfari , taurira chiremba wako nekukasika .
• Kuwedzera kwepfungwa dzekuzviuraya: Sezvinoita mimwe mishonga yekuora mwoyo, pane mukana mudiki wekuti vamwe vanhu vangave vaine pfungwa dzekuzviuraya kana zviito zvekuwedzera panguva yekutanga yekutora Spravato. Udza chiremba wako nekukasika kana uine shanduko itsva kana dzakakomba mumaitiro ako kana pfungwa dzako.

Kana paine emergency, fonerai Suwa Saria Ambulance Service pa1990 , kana fonerai nhare yekurapa nepfungwa pa1926. Kana kuti shanyirai Emergency Treatment Unit (ETU) iri pedyo .