Muviri wako wakaoma pasina chikonzero here? Ngatikurukurei nezveStiff Person Syndrome!

Dzimwe nguva unonzwa tsandanyama dzako dzichioma zvisinganzwisisike here, kana tsandanyama dzako dzichigwinha-gwinha zvinorwadza? Dzimwe nguva zvinogona kuitika kana ukanzwa ruzha rukuru kana mumwe munhu akakugumbura. Kana zvinhu izvi zvikaitika kakawanda, zvakanaka kuzviongorora. Nhasi tichataura nezvechirwere chisingawanzoitiki chinogona kukonzera zviratidzo zvakafanana. Izvozvo zvinonzi Stiff Person Syndrome (SPS) .

Chii chinonzi Stiff Person Syndrome?

Zvichitaurwa zviri nyore, Stiff Person Syndrome (SPS) chirwere chisingawanzoitiki chetsinga . Chinoitika kana masoja emuviri wedu, ayo anotidzivirira kubva kuzvirwere, achirwisa masero edu etsinga ane hutano. Ichi chirwere chinokonzerwa ne autoimmune. Izvi zvinoita kuti tsandanyama dziri pakati pedumbu, kunyanya dumbu, chipfuva, nemusana , dziome kana kuti dziome . Nekufamba kwenguva, kuomarara uku nekugwinha kunogona kupararira kune dzimwe tsandanyama dziri mumakumbo nemaoko. Izvi zvinogona kuita kuti zviome kufamba, kukuitisa kuti uwire kakawanda, uye kukuitisa kuti uve nenjodzi huru yekukuvara.

Iyi yaimbonzi "stiff man syndrome," asi zita iroro rachinjwa nekuti chirwere ichi chinogona kubata chero munhu, zvisinei nezera kana kuti murume kana mukadzi.

Kuonekwa uine chirwere ichi kunogona kunetsa zvishoma. Asi timu yako yezvekurapa ichagadzira hurongwa hwekurapa hunoshanda kwauri nezviratidzo zvako. Izvi zvinogona kusiyana kubva kumunhu kusvika kumunhu. Chinhu chakakosha ndechekuona vanachiremba vako nguva dzose, kuwana rutsigiro rwaunoda, uye kuedza kugara uine hutano hwakanaka.

Ndezvipi zviratidzo zveStiff Person Syndrome (SPS)?

Kune zviratidzo zviviri zvikuru zvechirwere ichi:

• Kuomarara kwetsandanyama kana kuomarara.
• Kurwadziwa kwetsandanyama.

Kunyangwe zviratidzo izvi zvichigona kutanga chero pazera ripi zvaro, zvinonyanya kuitika pakati pemakore makumi matatu nemakumi mana .

Zviratidzo zveStiff Person Syndrome zvinogona kupararira kune dzimwe nhengo dzemuviri uye zvinotowedzera kuipa nekufamba kwenguva. Kune vamwe vanhu, zvinogona kutora mwedzi kusvika makore kuti zviratidzo zvionekwe. Kune vamwe, zviratidzo zvinogona kuramba zvakafanana kwemakore. Kune vamwe vanhu, zviratidzo zvinogona kuwedzera zvishoma nezvishoma zvoita kuti zvisakwanise kuita mabasa ezuva nezuva.

Kuomarara kwetsandanyama

Kazhinji, chiratidzo chekutanga chaunoona neStiff Person Syndrome kuomarara kwetsandanyama muhudyu . Izvi zvinoreva kuti munzvimbo dzakadai sedumbu, chipfuva, nemusana. Kuomarara uku kunogona kukonzera kurwadziwa nekusagadzikana. Zviratidzo izvi zvinogona kuuya nekufamba pasina chikonzero chakajeka. Dambudziko iri rinogonawo kukanganisa maoko nemakumbo. Sezvo kuomarara kuchiwedzera, vamwe vanhu vanogona kuva nemaitiro asina kujairika anoita kuti zviome kufamba kana kufamba.

Kurwadziwa kwetsandanyama

Kurwadziwa kwetsandanyama ndeimwe chiratidzo chikuru chechirwere ichi. Izvi zvinogona kukanganisa muviri wese, kana kuti zvinogona kuitika munzvimbo yakati. Kurwadziwa uku kunogona kugara kwemasekondi, maminetsi, kana kunyange maawa. Fungidzira, paunenge wakangomira, gumbo rako kana musana wako zvinonzwa zvakamanikana uye zvichirwadza. Chiitiko chinorwadza zvikuru.

Ndezvipi zvinokonzera Stiff Person Syndrome (SPS)?

Pane zvikonzero zvinoverengeka nei zviratidzo zvakaita sekugwinha kwetsandanyama zvichigona kuoneka kamwe kamwe:

• Ruzha rwakangoerekana rwaitika kana kuti rukuru. Fungidzira kana waifamba mumugwagwa mota ikangoerekana yaridza huta yayo, kana kuti chimwe chinhu chiri kumba chikawira pasi neruzha rukuru.
• Kubatwa-batwa kana kukurudzirwa. Kana mumwe munhu akangoerekana akubata, anokurova.
• Kuchinja kwekupisa, kunyanya nzvimbo dzinotonhora. Kana ukangoerekana waenda kunzvimbo inotonhora, kana mvura inotonhora ikawira pamuviri wako.
• Zviitiko zvinoshungurudza. Nguva dzinoshungurudza uye dzinotyisa.

Nekuti kurwadza kwetsandanyama uku kunogona kuitika panguva dzisingatarisirwi, vamwe vanhu vane Stiff Person Syndrome vanonzwa kushushikana uye agoraphobia . Agoraphobia kutya zvakanyanya kuenda kunzvimbo dzakazara vanhu, kubuda panze, kana kubva pamba. Nekuti kana wabuda panze, zvinonetsa kutiza zvinokukurudzira izvi.

Chii chinokonzera Stiff Person Syndrome (SPS)?

Vaongorori havasati vava nechokwadi chekuti chii chinokonzera chirwere ichi, asi vanotenda kuti chirwere ichi chinokonzerwa ne autoimmune condition, zvichireva kuti masoja emuviri wedu anorwisa masero ane hutano.

Tsvagiridzo yakaratidza kuti ma antibodies anobatanidzwa. Vanhu vazhinji vane Stiff Person Syndrome vane ma antibodies anorwisa enzyme inonzi Glutamic Acid Decarboxylase (GAD) . Iyi enzyme (GAD) inobatsira kugadzira neurotransmitter gamma-aminobutyric acid (GABA) . Iyi neurotransmitter (GABA) inobatsira kudzora mashandiro emhasuru.

Asi vaongorori havasati vanyatsonzwisisa kuti enzyme `(GAD)` inokanganisa sei kukura nekufambira mberi kweStiff Person Syndrome. Chimwe chinhu chekurangarira ndechekuti kuva nema antibodies `(GAD)` mumuviri wako hazvirevi kuti une Stiff Person Syndrome. Chikamu chidiki chevanhu vose vanogona kunge vaine aya ma antibodies `(GAD)` mumiviri yavo pasina migumisiro yakaipa.

Pamusoro peGAD, mamwe ma antibodies akadai se glycine receptor, amphiphysin, uye DPPX (dipeptidyl peptidase-like protein 6) akaonekwa kuti ane chekuita nechirwere ichi. Zvakare, vamwe varwere vanogona kunge vasina ma antibodies aya. Tsvagiridzo yakawedzerwa iri kuenderera mberi kuti ione kuti ndeapi mamwe ma antibodies angave aripo.

Ndezvipi zvinhu zvinokonzera Stiff Person Syndrome (SPS)?

Stiff person syndrome inowanikwa kaviri muvakadzi . Inogonawo kuitika kune mamwe mamiriro ekudzivirira muviri. Semuenzaniso:

• Chirwere cheshuga cherudzi rwekutanga
• Chirwere chethyroid chinozvirwisa mumuviri
• Vitiligo
• Kupererwa neropa kwakaipisisa
• Chirwere cheCeliac

Chirwere cheStiff Person Syndrome (SPS) chakajairika zvakadii?

Ichi chirwere chisingawanzoitiki . Zvinonzi munhu mumwe chete pavanhu miriyoni ane chirwere ichi. Izvi zvinoreva kuti chirwere chisingawanzoitiki.

Chirwere cheStiff Person Syndrome (SPS) chinoonekwa sei?

Chiremba anoongorora chirwere ichi kuburikidza nezviratidzo, kuongororwa, uye bvunzo. Vachakubvunza nezvezviratidzo zvako, voita bvunzo yemuviri, uye voita bvunzo yetsinga.

Kana chiremba achifungidzira kuti ane chirwere cheStiff Person Syndrome, anogona kuita bvunzo dzakadai se:

• Kuongororwa kweropa remunhu ane ma antibodies: Izvi zvinobatsira kuona kana paine ma antibodies e (GAD) (kana mamwe ma antibodies ane chekuita nawo) uye kuona kuti hapana zvimwe zvirwere.
• Electromyography (EMG): Iyi inoyera mashandiro emagetsi emhasuru dzako. Izvi zvinogona kubatsira kubvisa zvimwe zvinokonzera zviratidzo zvako.
• Kuboorwa kwemusana (kupomba musana): Mubvunzo iyi, chiremba anoshandisa tsono kutora sampuli yemvura kubva mumusana wako uye anoiongorora kana paine ma antibodies kuGAD. Izvi zvakakoshawo kuti pasave nezvimwe zvirwere.

Chirwere cheStiff Person Syndrome chinogona kuoma kuona nekuti hachiwanzoitiki uye zviratidzo zvacho zvinogona kufanana nezvimwe zvirwere zvinodzivirira muviri, zvakaita seankylosing spondylitis uye multiple sclerosis.

Kune mhando dzeStiff Person Syndrome (SPS) here?

Kune mhando dzakasiyana dzechirwere ichi:

• Chirwere chepfungwa chemunhu akaomarara: Ichi ndicho chirwere chinowanzoonekwa. Chinowanzobatanidzwa nema antibodies eGAD, asi tsvakurudzo yakawana kuti mamwe ma antibodies anobatanidzwawo.
• Mhando dzeStiff person syndrome:Pasi peizvi, kune mhando dzinongobata nhengo dzemuviri chete, kana kuti dzinoratidza zviratidzo zvakawanda zvakaita sekurasikirwa nekuzvidzora paunenge uchifamba (`ataxia`).
• Progressive encephalomyelitis ine kuomarara uye myoclonus (PERM): PERM imhando ye stiff person syndrome yakanyanya kuipa. Inogona kukonzera kurasikirwa nepfungwa, matambudziko ekufamba kwemaziso, ataxia, uye autonomic dysfunction. Kusashanda zvakanaka kwe autonomic kunoda kuti vanhu vane PERM varare muchipatara.

Chirwere cheStiff Person Syndrome (SPS) chinorapwa sei?

Kune nzira mbiri huru dzekurapa izvi:

• Mishonga nekurapwa kudzora zviratidzo.
• Kurapa nekudzivirira chirwere, kana kuti kurapa kunochinja zvirwere.

Nzira dzekurapa dzinosiyana zvichienderana nezviratidzo zvako. Chinangwa chikuru chekurapa ndechekudzora maitiro anoita zviratidzo zvako uye kuvandudza kufamba kwako uye kugadzikana.

Chikwata chenyu chezvekurapa chingasanganisira nyanzvi dzakasiyana siyana, dzakadai se:

• Vanachiremba vetsinga, kunyanya vanachiremba vezvirwere zvetsinga.
• Varapi vezvemabasa nevanorapa nemuviri.
• Nyanzvi dzezvekurapa muviri nedzekudzoreredza hutano.
• Varapi vekutaura.
• Nyanzvi dzehutano hwepfungwa, semuenzaniso nyanzvi dzepfungwa.

Mishonga uye kurapwa

Mishonga yakaita seiyi inogona kubatsira kuderedza kuomarara kwetsandanyama, kuomarara, uye kurwadziwa kwetsandanyama:

• Benzodiazepines: Iyi imhando yemishonga inoshandiswa kurapa zvirwere zvakasiyana-siyana, zvinosanganisira kuzvidya mwoyo, pfari, uye kushaya hope. Inokanganisa mashandiro e neurotransmitter (GABA). Vanachiremba vanowanzo nyora diazepam senzira yekutanga yekurapa Stiff Person Syndrome.
• Zvinozorodza tsandanyama: Mishonga yakaita seBaclofen inogona kubatsira nekurwadziwa kwetsandanyama. Inozorodza tsandanyama uye inoderedza kuomarara.
• Mishonga yekurwadziwa kwetsinga: Mishonga yakaita segabapentin nepregabalin inokanganisawo zviratidzo zveGABA uye inobatsira nezviratidzo.

Mamwe marapirwo anogona kubatsira kudzora zviratidzo anosanganisira:

• Kurapwa kwemuviri kana kurapwa nebasa.
• Kukwiza muviri.
• Kurapa nemvura (hydrotherapy).
• Kurapa nekupisa.
• Kubata maronda.

Kurapa nekudzivirira muviri

Pane humbowo hunoratidza kuti kurapwa ne intravenous immunoglobulin (IVIg) (zvakare rudzi rwe immunotherapy) kunogona kubatsira kuderedza zviratidzo zve Stiff Person Syndrome. IVIg ine immunoglobulin (natural antibodies) inopiwa nezviuru zvevanhu vane immune system yakanaka.

Ko Stiff Person Syndrome (SPS) inogona kurapwa here?

Parizvino, hapana mushonga weStiff Person Syndrome. Kurapwa kunogona kungobatsira kudzora zviratidzo.

Ndeipi tarisiro yeStiff Person Syndrome (SPS)?

Ichi chirwere chisingaperi (chinotora hupenyu hwese) . Maonero acho anosiyana kubva pamunhu kuenda kune mumwe zvichienderana nezvinhu zvakati wandei:

• Kuoma kwezviratidzo.
• Kumhanya kwechirwere kwakapararira.
• Kurapa kwacho kunobudirira zvakadii?

Zvakakosha kutanga kurapwa kana zviratidzo zvatanga. Izvi zvinogona kubatsira kudzivirira kana kuderedza kupararira kwechirwere uye kudzivirira matambudziko kwenguva refu. Kunyange zvazvo vanhu vazhinji vachiwana zororo nemishonga, dzimwe nguva zvinogona kuoma kudzora zvinokonzera tsandanyama.

Kufamba kunogona kuramba kuchinetsa nekufamba kwenguva. Kukwanisa kuita mabasa ezuva nezuva kunogonawo kudzikira zvishoma nezvishoma. Sezvo chirwere ichi chichienderera mberi, njodzi yekudonha inowedzera. Ungangoda kushandisa tsvimbo, muchina wekufamba, kana kutoshandisa wiricheya.

Stiff Person Syndrome (SPS) inogona kudzivirirwa here?

Nekuti ichi chirwere chinokonzerwa ne autoimmune, hapana chaunogona kuita kuti chidzivirirwe .

Ndingazvitarisira sei kana ndine Stiff Person Syndrome (SPS)?

Kana zvichibvira, edza kutsvaga chiremba ane hunyanzvi mukutsvaga nekurapa Stiff Person Syndrome. Dambudziko iri hariwanzoitiki, saka rinogona kuoma zvishoma. Kana uchida kuwana rubatsiro rwekurapa rwakanakisisa uye kuva nehupenyu hwakanaka, uchafanira kutaura uye kuva nechido nazvo.

Zvakajairika kuti vanhu vane chirwere ichi vasangane nematambudziko ehutano hwepfungwa, akadai sekuzvidya mwoyo kana kuora mwoyo . Kana uri kusangana nezviratidzo izvi, zvakakosha kutaura nachiremba wako kana nyanzvi yehutano hwepfungwa, senge chiremba wepfungwa.

Kana iwe nemhuri yako muchikwanisa, munogonawo kujoina boka rekutsigirana kwamunogona kusangana nevamwe vanonzwisisa zvamunosangana nazvo.

Ndinofanira kuona chiremba rini?

Kana uine Stiff Person Syndrome, unofanira kusangana nechikwata chako chekurapa nguva nenguva kuti uone kana kurapwa kwako kuri kubudirira uye kuti utarise kukura kwezviratidzo zvako.

Kana ukaona zviratidzo zvitsva kana kuti une migumisiro yakaipa kubva mumishonga, udza chiremba wako.

Mibvunzo ipi yandinofanira kubvunza chiremba wangu?

Kana uine Stiff Person Syndrome, zvingabatsira kubvunza chiremba wako mibvunzo iyi:

• Ndeapi marapirwo amunokurudzira pazviratidzo zvangu?
• Ndingaitei kumba kuti ndibatsire nezviratidzo zvangu?
• Ndezvipi zviratidzo zvematambudziko andinofanira kutarisa?
• Ndingatarisira kuti hutano hwangu huve hwakaita sei mune ramangwana?
• Pane here miedzo yekiriniki yeStiff Person Syndrome?

Pakupedzisira, zvinhu zvekurangarira (Mharidzo Yekuenda Kumba)

Kuziva kuti une chirwere chisingawanzoitiki chakadai seStiff Person Syndrome hakusi nyore. Unganzwa wakaremerwa, uchinetseka, uye usina chokwadi nezveramangwana. Asi haufanirwe kutarisana neizvi wega. Chikwata chako chekurapa chiripo kuti chipindure mibvunzo yaungave nayo uye chikubatsire kudzora zviratidzo zvako.

Kunyange hazvo kurapwa kwako kuchinyanya kutarisisa hutano hwako hwemuviri, fungawo nezvehutano hwako hwepfungwa . Zviratidzo zvinosiyana kubva pamunhu kusvika pamunhu. Asi kurarama nemarwadzo, kusagadzikana, uye kugwinha kwetsandanyama kusingatarisirwi kunogona kukanganisa hutano hwako hwepfungwa. Dambudziko iri rinogona kuita kuti zviomere kubuda kunze kunoita mabasa ezuva nezuva. Saka, kana uchida rutsigiro, usazeza kutaura nachiremba pamwe chete nevadikanwi vako. Yeuka, hausi wega.

` Stiff Person Syndrome, kuomarara kwetsandanyama, zvirwere zvetsinga, autoimmune, maGAD antibodies, GABA, kugwinha kwetsandanyama, zviratidzo zveSPS