Uri kunzwa mapundu pedyo nemajoini ako here? Ngatikurukurei nezve Tumoral Calcinosis!

Dzimwe nguva unonzwa sekuti une bundu kana nzvimbo yakaoma pasi peganda pedyo nejoini rako segokora, fudzi, kana ibvi? Ringasarwadze kana ukaridzvanya, asi rinogona kukura zvishoma. Zvakajairika kuti unzwe kutya zvishoma kana ukaona chimwe chinhu chakadai. Asi haasi mapundu ese aya ane njodzi yekenza. Nhasi tichataura nezvechirwere chinoratidza zviratidzo izvi, asi chisiri kenza, uye chisingawanzoitiki asi chakakosha kuziva nezvacho. Ndiyo 'Tumoral Calcinosis' .

Chii chinonzi Tumoral Calcinosis?

Zvichitaurwa zviri nyore, tumoral calcinosis chirwere chemajini . Apa ndipo apo huwandu hwekemikari muropa rako inonzi phosphate hwakakwira zvakanyanya. Phosphate chinhu chine phosphorus, kana kuti ion, chine mineral phosphorus. Saka, mumunhu ane tumoral calcinosis, phosphorus necalcium zvinoungana mumuviri, zvichiita kuti mapundu aumbe pasi peganda, kunyanya kutenderedza majoini.

Zvese phosphorus necalcium zvakakosha kuti miviri yedu ivake mazino nemapfupa ane hutano uye akasimba. Asi kana zvanyanya kukwira, kukura kusiri kwekenza (kusingakuvadzi), ndiko kuti, hakuna njodzi, asi kunoita semamota, kunotanga kuumbwa munyama. Izvi ndizvo zvatinodaidza kuti tumoral calcinosis.

Pane rimwe zita reizvi here?

Ehe, zita rakazara rekurapa rechirwere ichi ndi 'Hyperphosphatemic Familyal Tumoral Calcinosis' (HFTC) . Zita refu, handiti? Vamwe vanachiremba vanoritiwo 'chirwere cheTeutschlaender'. Izvi ndizvo zvekurangarira Otto Teutschlaender, chiremba wekuGermany akadzidza nezvechirwere ichi kubva kuma1930 kusvika kuma1950.

Zita iri refu rezvekurapa rinorevei?

Tingaita kuti zita iri rive muzvikamu zvakasiyana here torinzwisisa? Izvozvo zvingava nyore.

• Hyperphosphatemic: Izvi zvinoreva kuti huwandu hwephosphate muropa hwakakwira.
• Zvemhuri: Izvi zvinoreva kuti ichi chirwere chinoitika mumhuri uye chinogara nhaka.
• Bundu: Izwi iri rinoshandiswa nekuti bundu iri rakaita sebundu rinoita sebundu rekenza.
• Calcinosis: Izvi zvinoreva kuti calcium inochengetwa munyama dzemhasuru dzako nehurongwa hwemapfupa nemapfupa.

Wava kunzwisisa zvinorehwa nezita iroro refu here?

Tumoral Calcinosis inokanganisa sei muviri?

Mapundu aya, anonzi tumoral calcinosis , anowanzo umbwa pasi peganda, pedyo nemajoini . Anogona kukura mumajoini anopfuura rimwe chete, asi anogonawo kukura mumajoini akawanda. Nzvimbo dzinonyanya kuwanikwa ndeidzi:

• Majoini ehudyu
• Magokora
• Mapendekete
• Pasi
• Majoini echanza
• Zvine chekuita nemutsipa wemusana
• Nzvimbo yeshaya

Dambudziko iri rakajairika zvakadii?

Nyanzvi dzezvekurapa hadzina chokwadi chekuti vangani vane chirwere ichi chegomarara. Nekuti chirwere ichi hachiwanzoitiki , chinowanzoitika kuvanhu vane dzinza reAfrica neMiddle East. Chinogona kubata varume nevakadzi.

Ndeapi marudzi makuru eTumoral Calcinosis?

Rudzi rwakajairika rweizvi iHyperphosphatemic Familyal Tumoral Calcinosis, yatakambokurukura nezvayo. Pamusoro pezvo, kune mamwe marudzi asingawanzoitiki:

• Hyperphosphatemia-hyperostosis syndrome (HHS): Ichi chirwere chinokonzera kukura kwemapfupa zvakanyanya uye kukura kwezvironda zvemapfupa zvisina kenza.
• Normophosphatemic tumoral calcinosis: Rudzi urwu runowanzoonekwa muvanhu vane dambudziko reitsvo. Runogona kukonzera chirwere chinonzi hyperparathyroidism, chinova chirwere cheparathyroid gland chinoshanda zvakanyanya.

Chii chinokonzera Tumoral Calcinosis?

Tumor calcinosis chirwere chemetabolic chinowanikwa nhaka . Vanhu vanosvika chikamu chimwe muzvitatu vane chirwere ichi vane shanduko, kana kuti mutation, mujini ravo reFGF23. Jini reFGF23 rinobatsira masero edu emapfupa kugadzira protein inonzi fibroblast growth factor (FGF) 23. Vamwe vanhu vane chirwere ichi nekuda kwekuchinja kwemajini eGALNT3 neKL. Majini aya anodzora kugadzirwa kweFGF23. Vanhu vane nomophosphatemic tumor calcinosis vane mutation mujini reSAMD9.

Kazhinji, puroteni inonzi `FGF23` inoudza itsvo dzedu kuti ingani phosphate inofanira kutorwa kubva muropa. Asi kana paine shanduko yemajini, maitiro aya anokanganiswa. Ipapo itsvo dzinotorazve phosphate yakawanda kupfuura yadzinofanira kutora. Kazhinji, itsvo dzinoburitsa phosphate yakawandisa muweti. Asi mu tumor calcinosis, phosphate iyi inosunga calcium uye inoumba tumors munyama dzakapfava.

Ndiani ari panjodzi yekuva nechirwere ichi?

Tumorous calcinosis chirwere chinokonzerwa ne autosomal recessive . Izvi zvakaoma kunzwisisa, asi zviri nyore, kuti uve nechirwere ichi, unofanira kugara nhaka gene mutation kubva kuvabereki vako vese. Vabereki vako vanogona kunge vari ivo vanotakura mutation, asi vanogona kunge vasina chirwere ichi.

Kana vabereki vese vari vaviri vane chirwere ichi, mwana mumwe nemumwe ane mikana inotevera:

• Pane mukana mumwe chete pavana wekusava nejini rakachinja (hapana njodzi yekuva nechirwere ichi).
• Pane mukana mumwe chete pavana wekubatwa nekenza ye calcinosis.
• Pane mukana mumwe chete pavaviri wekuti munhu awane chirwere ichi asingatapurike.

Ndezvipi zviratidzo zveTumoral Calcinosis?

Dambudziko iri rinoita kuti mapundu ane saizi dzakasiyana aumbe pedyo nepfundo rimwe chete kana kupfuura. Mapundu aya anowanzoonekwa muhudiki kana kuyaruka . Zvisinei, anogonawo kukura muvacheche nevakuru. Dzimwe nguva, mapundu mashoma chete anokura muhupenyu hwese. Kana kuti, mapundu akawanda anogona kukura panguva imwe chete.

Unogona kuva nezviratidzo zvakaita seizvi:

• Kuomerwa nekufambisa kana kukotama zvakanaka kwejoini rakakanganiswa.
• Mapundu akaomarara asingarwadzi (mamwe mapundu anogona kurwadza zvishoma kana akagunzwa).
• Kurwadziwa kwetsandanyama.

Tumoral Calcinosis inoonekwa sei?

Chiremba wemapfupa chiremba ane hunyanzvi mumatambudziko emapfupa nemapfundo. Achakuongorora uye achakubvunza nezvezviratidzo zvako. Anogona kuita imwe kana anopfuura eX-rays anotevera kuti aone bundu iri nemamwe matambudziko emapfupa:

• Kuongororwa kweX-ray `(X-ray)`
• Kuongororwa kweCT
• Kuongororwa kweMRI `(MRI)`

Ndezvipi zvimwe zvirwere zvinoratidza zviratidzo zvakafanana neTumoral Calcinosis?

Izvi zvakakosha zvikuru. Nekuti zvakakosha kuti munhu awane chirwere chakakodzera . Chikonzero ndechekuti kune zvimwe zvirwere zvinoratidza zviratidzo zvakafanana, asi zvakanyanya kuipa. Zvimwe zvezvirwere izvi ndeizvi:

• Mabundu enyama yakapfava asina kunaka uye mabundu enyama yakapfava ane kenza
• Calcific myonecrosis (bundu rine calcium yakawanda mutsandanyama dzemakumbo)
• Calcific tendonitis (calcium yakachengetwa pamwe chete netendonitis)
• Calcinosis circumscripta (calcium inowanikwa muganda nenyama dzemaoko netsoka)
• Calcinosis yekusashanda zvakanaka kweitsvo (itsvo) (calcium inochengetwa muvanhu vari pa dialysis)
• Calcinosis universalis (kuiswa kwecalcium munyu muganda, munyama, mutsinga, uye mutsandanyama)
• Zvirwere zvekubatana kwenyama
• Gout
• Myositis ossificans (tsandanyama inoshanduka kuita pfupa)
• Osteosarcoma uye sarcoma (kenza yemapfupa)
• Synovial chondromatosis (mapundu ecartilage mumajoini)

Maona? Kunyangwe zviratidzo zvakafanana, chikonzero chacho chinogona kusiyana zvikuru. Ndosaka zvichikosha kuti uzive zviri kuitika chaizvo.

Ndezvipi zvirongwa zvekurapa zvisina kuvhiyiwa?

Chiremba wako anogona kuderedza huwandu hwephosphate muropa rako.Mishonga inosunga phosphate inogona kunyorerwa. Kana mishonga iyi inosunga phosphate ikasanganiswa nemushonga unonzi acetazolamide (unowanzo shandiswa pakurapa pfari ne glaucoma), inogona kuvharira muviri kuti usakwanise kupinza phosphorus. Ungangodawo kudya chikafu chine phosphorus shoma .

Chii chinonzi kudya kushoma kwephosphorus?

Kana uine tumoral calcinosis, chiremba wako anogona kukurudzira kudya chikafu chine phosphorus shoma. Phosphorus inowanikwa munyama, hove, uye zvigadzirwa zvemukaka. Phosphorus inowedzerwawo kune zvimwe zvekudya senzira yekuchengetedza kana kunakirwa.

Edza kuderedza zvekudya nezvinwiwa zvine phosphorus yakawanda, zvakaita se:

• Doro, colas, tii inotonhora uye zvinwiwa zvechokoreti.
• Mhando dzechokoreti necaramel.
• Zvikafu zvemukaka (mukaka, chizi, aizi kirimu, yogati dzisiri dzechiGiriki, soups dzine kirimu).
• Hove dzakadai seoyster nemasadhini, uye nhengo dzemukati dzakadai senyama yemombe nechiropa chehuku.
• Nyama dzakagadzirwa (hot dogs, nyama yemasikati, bhekoni, masoseji).
• Zvigadzirwa zvakagadzirwa ne oat bran.

Zvakanaka kutaura nachiremba wako kana nyanzvi yezvekudya nezvenyaya iyi kuti uwane rumwe ruzivo.

Ndezvipi zvirongwa zvekuvhiya?

Ungangoda kuvhiyiwa kuti ubvise bundu rakakura zvekuti harishande zvakanaka. Zvisinei, bundu iri rinogona kukura zvakare . Chiremba wako anogonawo kutora sampuli yenyama yakabviswa obva aita biopsy kuti asimbise chirwere chacho.

Ndezvipi zvinetso zvinogona kuitika nekuda kweTumoral Calcinosis?

Kashoma, chirwere ichi chinogona kukanganisa mitsipa yeropa kana uropi, zvichiwedzera njodzi yako yezvirwere zvakakomba zvakaita sechirwere chemwoyo uye sitiroko.

Uyezve, chirwere ichi chinogona kukonzera zvinotevera:

• Kuumbwa kwemasero eropa mu cornea kana kuti mitsetse mitsvuku (mitsetse mitsvuku) mu cornea yemaziso.
• Matambudziko emazino.
• Kukura kwakanyanya kwemapfupa (hyperostosis).
• Kuzvimba kwemapfupa marefu (diaphysis) mumakumbo kana mumaoko ako.

Ko Tumoral Calcinosis inogona kudzivirirwa here?

Kana iwe nemumwe wako muine gene mutation inokonzera tumoral calcinosis, munogona kutaura nenyanzvi yezvemajini nezvenzira dzekuderedza njodzi yekuti vana venyu vagare nhaka yemutation iyi. Vamwe vanhu vanosarudza nzira inonzi Preimplantation Genetic Diagnosis (PGD) . Izvi zvinosanganisira kuona maembryo asina mutation iyi. Chiremba wenyu anoshandisa nzira inonzi In Vitro Fertilization (IVF) kuendesa maembryo ane hutano mudumbu remukadzi. Nenzira iyi, mwana wenyu haazogari nhaka yemutation iyi inokonzera chirwere ichi.

Ndeipi tarisiro yemunhu ane Tumoral Calcinosis?

Vanhu vazhinji vane tumoral calcinosis vanorarama hupenyu hwakakwana uye hune simba . Dambudziko iri hariwanzo kukonzera matambudziko makuru ehutano. Zvisinei, uchafanira kuona chiremba wako nguva nenguva kuti utarise kana chirwere ichi chichidzoka zvakare.

Ndinofanira kuona chiremba rini?

Ona chiremba kana uine zviratidzo izvi:

• Kuderera kwekufamba kwejoini.
• Kurwadziwa kwemajoini, kurwadziwa kwemapfupa, kana kurwadziwa kwetsandanyama.
• Kuonekwa kwebundu kana kuti bundu riri pasi peganda.

Chii chandinofanira kubvunza chiremba wangu?

Unogona kubvunza chiremba mibvunzo yakaita seiyi:

• Sei ndakaita tumor calcinosis?
• Ndeipi nzira yakanakisisa yekurapa?
• Ndinoda kuvhiyiwa here?
• Ndinofanira kuderedza kudya kwerudzii?
• Ndinofanira kunetseka nezvematambudziko here?
• Vamwe vese vemhuri yangu vanofanira kuongororwa majini here?

Ko Tumoral Calcinosis inogona kuva kenza here?

Pasinei neshoko rekuti "bundu" muzita racho, bundu rinokura nekuda kwebundu re calcinosis harisi regomarara . Hapana njodzi yekuti bundu iri rive regomarara. Saka usazvidya moyo nazvo.

Ichokwadi kuti bundu riri pasi peganda rinokonzerwa nebundu re calcinosis rinogona kushungurudza zvishoma uye kutyisa. Asi kune vanhu vazhinji, bundu iri harikonzeri matambudziko makuru. Mishonga inogona kuderedza huwandu hwe phosphorus muropa. Chiremba wako anogonawo kukurudzira kuti uone nyanzvi yezvekudya kuti akubatsire kudya chikafu chine phosphorus shoma. Kana uine kurwadziwa mumajoini ako, mapfupa, kana tsandanyama zvinokutadzisa kufamba zvakanaka, udza chiremba wako. Kunyangwe bundu richigona kubviswa nekuvhiyiwa, yeuka kuti rinogona kudzoka.

Mharidzo Yekuenda Nayo Kumba (Zvinhu Zvekurangarira)

Zvakanaka, ngatidzokororei pfungwa dzakakosha dzatakakurukura nhasi nezve Tumoral Calcinosis:

• Ichi chirwere chisingawanzoitiki, chinogara nhaka. Kuwedzera kwephosphate muropa kunoita kuti zvisanganiswe necalcium kuti zvigadzire mapundu pedyo nemajoini.
• Mabundu aya haasi ekenza .
• Izvi hazviwanzo rwadza, asi zvinogona kukanganisa kufamba kwemajoini.
• Kurapa kunosanganisira mishonga inoderedza phosphate, kudya kusina phosphorus yakawanda, uye, kana zvichidikanwa, kuvhiyiwa.
• Kana ukaona bundu rakadai, usavhunduka wotsvaga rubatsiro kuna chiremba. Kuongororwa kwakarurama kwakakosha zvikuru.
• Vanhu vazhinji vanorarama hupenyu hwakajairika uye hune simba vaine chirwere ichi.

Saka, kana iwe kana mumwe munhu waunoziva aine zviratidzo izvi, zvakanaka kuti uone chiremba kuti akupe mazano.

` Tumorous calcinosis, majoini anobuda, phosphate, calcium, zvirwere zvemajini, mapundu eganda, zvirwere zvemapfupa