Ngaba ukhe weva ngolu hlobo lwethumba olukhula kwii-ovari? (I-Granulosa Cell Tumor) Masithethe ngayo!

Usenokuba awukaze uve eli gama ngaphambili – I-Granulosa Cell Tumor luhlobo olungaqhelekanga lwethumba olunokuvela kuma-ovari abasetyhini. Kodwa ungoyiki xa usiva igama, kulungile? Siza kuthetha ngale nto ngokulula, ukuze uyiqonde. Kuba, kubaluleke kakhulu ukwazi ngayo nantoni na.

Yintoni iGranulosa Cell Tumor? Masiyiqonde ngokulula!

Ngamafutshane, le `(Granulosa Cell Tumor)` sisimila esikhethekileyo (isimila) esikhula kwii-ovari zethu zabasetyhini . Njengoko usazi, ii-ovari, sisitho esibaluleke kakhulu emzimbeni wethu esivelisa amaqanda, kunye neehomoni zabasetyhini ezifana ne`(Estrogen)` kunye ne`(Progesterone). Olu hlobo lwesimila, ukuba sichanekile, lukwisigaba se`(sex cord-stromal tumor)`. Xa esi sifo sikhula, inqanaba le`(Estrogen)` emzimbeni lidla ngokwanda kakhulu . Nangona oku kunokukhula nakweyiphi na iminyaka, kuhlala kubonakala malunga neminyaka engama-50.

Zenzeka phi ezi thumba?

Ii-Granulosa cell tumors (GCTs) zikhula kwii-ovari . Ii-ovari ziyinxalenye yenkqubo yokuzala yabasetyhini. Ukongeza ekuveliseni amaqanda (ii-ovari), ii-ovari zikwavelisa iihomoni zokuzala i-estrogen kunye ne-progesterone.

Zixhaphake kangakanani ezi zinto?

Ezi zinqabile kakhulu , ezibizwa ngokuba yi-"Granulosa Cell Tumors". Zenza malunga ne-5% yee-ovarian tumors eziphambili. Ngoko ke, njengoko ubona, oku akuqhelekanga kangako.

Ngaba ezi zizifo zomhlaza? Okanye zizifo nje?

Umbuzo omkhulu kubantu abaninzi kukuba ingaba lo ngumhlaza oyingozi okanye sisimila nje. Enyanisweni, ezi tumors zeseli ze-granulosa kusenokwenzeka ukuba zinobungozi, okanye zinomhlaza .

Kodwa, kukho iindaba ezimnandi apha. Olu hlobo lwee-tumor (GCT) luhlala lukhula kancinci . Oko kukuthi, azisasazeki ngokukhawuleza. Ke ngoko, oogqirha banokuzifumanisa kwangethuba, kwaye amathuba okufumana iziphumo ezilungileyo kunyango aphezulu.

Ngaba kukho umahluko phakathi kweGranulosa Cell Tumor kubantu abadala nakubantu abancinci?

Ewe, kukho umahluko omncinci apha. Ezi thumba zibonakala kakhulu kubafazi abadala. Enyanisweni, i-95% yazo zonke izifo ze-GCT ezifunyanisiweyo zikwiibhinqa ezindala ezikhule kakuhle .

Nangona kunjalo, kunqabile, ukuba eli thumba likhula kumntu ongaphantsi kweminyaka engama-30, libizwa ngokuba yi-juvenile granulosa cell tumor (JGCT) . Olu hlobo lwethumba olukhula kubantu abancinci, ukuba lusasazeke ngaphandle kwe-ovary, ngamanye amaxesha lunokuphinda lubuye kwiminyaka embalwa kunohlobo olukhula kubantu abadala., kwaye ingaziphethe ngendlela enobundlobongela kancinci.

Kutheni ezi thumba ze-granulosa cell zenzeka? Yintoni imbangela?

Le yingxaki abantu abaninzi abanayo. Enyanisweni, iingcali zonyango azikayiqondi ngokupheleleyo into ebangela oku . Nangona kunjalo, into abayifumanisileyo kukuba abantu abaninzi abanezi thumba banotshintsho, okanye utshintsho, kwi-gene ebizwa ngokuba yi-``(FOXL2)``. Ngokwesiqhelo, le gene ``(FOXL2)`` inceda iiseli ze-granulosa zikhule ngokufanelekileyo nasempilweni. Ngoko ke, ukuba kukho utshintsho kule gene, kucingelwa ukuba isenokuba sesinye sezizathu zokuba ezi thumba zikhule.

Zithini iimpawu zeGranulosa Cell Tumor?

Uphawu oluphambili olubonakala koku kukunyuka kwenqanaba le-hormone ye-estrogen emzimbeni .

• Kwintombazana eselula , le estrogen igqithisileyo inokubangela ukuba idlule ebusheni kwangethuba . Oku kuthetha ukuba inokukhula amabele ngaphambi kweminyaka eqhelekileyo ize ikhule iinwele kwiindawo zabucala.
• Abafazi abadala badla ngokufumana iimpawu ezifana nezi:
• Ukopha okungaqhelekanga kwesibeleko (AUB) okanye ukopha emva kokuya exesheni luphawu olubaluleke kakhulu.
• Ukuvuvukala kwesisu (ukuziva uzele) .
• Ukuya exesheni okungaqhelekanga okanye ukuyeka ngokupheleleyo ukuya exesheni kangangexesha elithile.
• Intlungu yebele, ukuthamba (amabele athambileyo okanye abuhlungu) .

Ngamanye amaxesha, le thumba inokubangela iintlungu zesisu kuphela xa igqabhukile . Kodwa oko akwenzeki kuwo wonke umntu.

Ziziphi iingxaki ezinokwenzeka ngenxa yesi sifo?

Ukuba le thumba yeseli ye-granulosa ayinyangwanga kakuhle, inokunyusa umngcipheko wezinye iingxaki zempilo. Yiyo loo nto kubalulekile ukuyixilonga nokuyinyanga ngokukhawuleza. Ezinye zeengxaki eziphambili ezinokubakho zezi:

• I-Endometrial hyperplasia : Oku kungaba sisiseko somhlaza wesibeleko.
• Umhlaza wesibeleko .
• Umhlaza webele .
• Ubunzima bokufumana abantwana (Ukungazali) .

Oogqirha bayixilonga njani le `(Granulosa Cell Tumor)`?

Ngokwesiqhelo, oogqirha basebenzisa iindlela ezahlukeneyo zokuthatha imifanekiso ukuze baxilonge iithumba zeseli ze-granulosa. Kusenokufuneka wenze uvavanyo olufana nolu:

• I-CT scan .
• Iskeni ye-MRI .
• I-ultrasound edluliselwa kwisini : Oku kuvumela ukuba ama-ovari abonakale ngokucacileyo.

Ukongeza, ugqirha wakho unokuyalela uvavanyo lwegazi . Ngokukodwa, baya kukhangela into ebizwa ngokuba zii-tumor markers . I-Inhibin luphawu olukhethekileyo oluveliswa zezi tumors zeseli ze-granulosa kwaye zinokufumaneka egazini. Banokuyalela novavanyo oluthile lwegazi ukuze basuse ezinye iimeko.

Zinyangwa njani iithumba ze-granulosa cell?

Unyango lokuqala noluphambili loku lutyando . Ugqirha uzama ukususa ithumba elininzi kangangoko kunokwenzeka, ngelixa eqaphela ukuba angonakalisi izicubu eziphilileyo.

• Ukuba awusafuni ukuba nabantwana, okanye ukuba sele udlulile kwiminyaka yokuzala, ugqirha wakho unokucebisa ukuba kususwe ii-ovari zakho (oophorectomy) kwaye mhlawumbi nesibeleko sakho (hysterectomy) . Kwezinye iimeko, ukususwa kwee-ovari kuyimfuneko ukuze kususwe yonke i-GCT.

Okulandelayo, oogqirha bafumanisa ukuba ithumba lisasazeke kangakanani, okanye ukuba ingakanani inqanaba lethumba . Le yindlela abafumanisa ngayo ukuba umhlaza usasazeke okanye akunjalo.

• Isigaba soku-1 se-GCTs sithetha ukuba ithumba alisasazekanga ngaphandle kwama-ovari.
• Isigaba sesi-2 ukuya kwesesi-4 se-GCTs sithetha ukuba ithumba lisasazekile (lisasazeke) kwamanye amalungu omzimba.

Khawucinge nje, eyona nto ilungileyo kukuba ii-GCT ezili-9 kwezili-10 zifumaneka ngaphakathi kwi-ovary . Kwezi ntlobo zeethumba, utyando ludla ngokucetyiswa, kwaye lusenokuba lolona nyango kuphela.

Nangona kunjalo, kuxhomekeke kubukhulu bethumba kunye nezinto ezinokubangela ukuba liphinde libuye, unyango olongezelelweyo lunokunikwa ukuthintela ukuba ithumba lingaphindi libuye. Ugqirha wakho unokucebisa oku kulandelayo:

• Unyango ngamakhemikhali
• Unyango lwehomoni
• Unyango ngemitha

Ngaba ikho indlela yokuthintela ukwakheka kwesi sifo se-granulosa?

Akukho ndlela iqinisekileyo yokuthintela oku ukuba kungenzeki . Nangona kunjalo, ukuphila ubomi obusempilweni nokunciphisa umngcipheko wezifo ezingapheliyo kunokunceda ngandlela ithile. Oko kuthetha ukuba:

• Ukugcina ubunzima obusempilweni obuhambelana nohlobo lomzimba wakho, isini, kunye nobudala.
• Ziphephe ngokupheleleyo ukutshaya .
• Ukutya ukutya okunesondlo (imifuno, iziqhamo, kunye nemifuno emininzi).
• Ukuzilolonga rhoqo kubalulekile kwimpilo yentliziyo kunye namandla amathambo.
• Ukunciphisa ukusetyenziswa kotywala kunye ne-caffeine .
• Ukulawula uxinzelelo ngezinto ezifana nokucamngca kunye neyoga.
• Lala kakuhle ubuncinane iiyure ezisixhenxe ukuya kwezisibhozo ngobusuku.

Ungayinciphisa njani ingozi yeengxaki ezivela kwi-`(Granulosa Cell Tumor)`?

Eyona nto ibalulekileyo kukubona ugqirha ngokukhawuleza ukuba uneempawu ezinokuba zinxulumene ne-`(GCT)` . Ingakumbi, ukuba unesifo sokopha esingalawulekiyo, iintlungu zebele, ukuqaqamba, okanye ukopha emva kokuya exesheni, ngokuqinisekileyo kufuneka ufune ingcebiso kagqirha . `(GCT)` idla ngokuba yimpumelelo enkulu xa inyangwa kwangethuba.

Ngaba iithumba ze-granulosa cell zinokunyangwa?

Ewe, iyanyangeka . Amathuba okuphiliswa aphezulu ukuba la mathumba asuswa kwangethuba , ingakumbi ngotyando.

Nangona kunjalo, ukuba ugqirha uyifumene, akunakwenzeka ukuba inyange i-GCT ukuba sele isasazeke kwamanye amalungu omzimba. Yiyo loo nto sisoloko sisithi ukuba uneempawu ze-GCT, bonana nogqirha ngoko nangoko .

Yintoni onokuyilindela emva konyango lwe-`(GCT)`?

Emva kokuba ithumba lisusiwe, kuya kufuneka ubone ugqirha wakho rhoqo kangangeminyaka eliqela ukuze kulandelelwe . Oku kungenxa yokuba amathumba ngamanye amaxesha anokubuya emva kweminyaka. Ugqirha wakho uya kujonga rhoqo ukuze abone ukuba ithumba libuyile na. Oku kunokuquka:

• Uvavanyo lwe-pelvic .
• Uvavanyo lwegazi ukujonga iimpawu zokubuyela komhlaza.
• Uvavanyo lokuskena .

Iyintoni imbonakalo yeethumba ze-granulosa cell?

Imbonakalo ye-GCT ixhomekeke ekubeni iqhubu lihambe kangakanani (inqanaba) xa uxilongwa . Ukuba ugqirha wakho ufumanisa i-GCT ngaphambi kokuba isasazeke (ikhule) kwezinye iindawo zomzimba, imbonakalo idla ngokuba ntle .

Yintoni enye endifanele ndiyibuze kugqirha wam?

Ukuba ufuna ukwazi okungakumbi ngale nto, ungabuza ugqirha wakho imibuzo efana nale:

• Yintoni enokubangela iimpawu zam?
• Zeziphi iimvavanyo ekufuneka ndizenze ukuqinisekisa ukuba ndineGranulosa Cell Tumor?
• Ziziphi iindlela zonyango endinazo?
• Lingakanani ithuba lokuba le `(GCT)` ibuyele emva konyango?
• Injani imbono yam emva kokususwa kwethumba le-granulosa cell?

Izinto ezibalulekileyo ekufuneka uzikhumbule kweli nqaku (Umyalezo Wokuya Ekhaya)

Kulungile, ngoko ke, ngokwezinto esithethe ngazo, ezi zezona zinto zibalulekileyo ekufuneka uzikhumbule:

• I-Granulosa cell tumor yi -tumor engaqhelekanga, edla ngokuba yi-benign tumor ekhula kwii-ovari .
• Rhoqo ngenxa yezi zintoAmanqanaba e-estrogen emzimbeni ayanda.
• Ngoko ke, iimpawu ezinje ngokopha okungaqhelekanga kwesibeleko, imijikelo yokuya exesheni engaqhelekanga, kunye nokukhula kwesisu kunokwenzeka.
• Unyango oluphambili kukususa ithumba ngotyando .
• Eyona nto ibalulekileyo kukuba ukuba ezi zinto zifunyenwe kwangethuba, amathuba okuchacha aphezulu kakhulu .
• Ngoko ke, ukuba unenye yezi mpawu, musa ukoyika okanye ukulibazisa, kodwa bonana nogqirha ngokukhawuleza ukuze akunike icebiso .

Ndiyathemba ukuba olu lwazi uza kulufumana luluncedo. Hlala usempilweni!

Ithumba leseli yeGranulosa , umhlaza wesibeleko, i-estrogen, impilo yabasetyhini, ukopha okungaqhelekanga, iimpawu zomhlaza, utyando