Yintoni iCholecystokinin? Masithethe ngayo ngokulula!

Molo! Unjani? Namhlanje siza kuthetha ngesithunywa sekhemikhali esincinci kodwa esibaluleke kakhulu emzimbeni wethu. Sibizwa ngokuba yi-cholecystokinin. Nangona igama lisenokubonakala lide kancinci, libalulekile kwinkqubo yethu yokugaya ukutya. Makhe sibone ukuba lenza ntoni, lisebenza njani, kwaye libaluleke kangakanani emzimbeni wethu?

Yintoni le cholecystokinin?

Ngamafutshane, i-cholecystokinin yi -hormone . Uyazi ukuba zeziphi ii-hormone? Zifana nezithunywa ezincinci ezithwala imiyalezo ukusuka kwenye indawo ukuya kwenye emizimbeni yethu. Le hormone ebizwa ngokuba yi-cholecystokinin iveliswa kakhulu ziiseli ezisemathunjini akho amancinci , ingakumbi emva kokuba sityile. Yiyo loo nto ngamanye amaxesha ibizwa ngokuba yi-pancreozymin. Ibizwa njalo kuba isebenza kwi-pancreas. Kodwa okumangalisayo kukuba, le cholecystokinin ikwakho nakwingqondo yethu nakwinkqubo ye-nervous central . Izazinzulu zisafumanisa ukuba yenza ntoni apho. Kodwa indima yayo ekugayweni kokutya inkulu kakhulu.

Iqala njani ukukhutshwa kwe-cholecystokinin?

Khawuthelekelele ukuba utye isidlo esimnandi. Mhlawumbi i-meat curry enerayisi, okanye iqhekeza lentlanzi, iilentils, i-coconut sambol... Ukutya okutyayo kuqala kuya esiswini. Kugaywa apho okwethutyana, kwaye kancinci kancinci kuqala ukufikelela kwinxalenye yokuqala yamathumbu amancinci, i-duodenum . Kufana nololiwe oza kwisikhululo. Emva koko, kukho iiseli ezikhethekileyo eludongeni lwe-duodenum yakho, njengabacuphi. Zibizwa ngokuba zii-I-cells . Ezi-I-cells zinamandla amangalisayo okubona iiproteni kunye namafutha (oko kukuthi, inyama, intlanzi, amaqanda, ubisi, iioyile) ekutyeni okutyayo. Ngokukhawuleza nje xa bezibona, ezi '(ii-I-cells)' zicinga, "Owu, ngoku lixesha lokuba siqale ishishini! Kufuneka sikhuphe umhlobo wethu i-cholecystokinin ngokukhawuleza," kwaye bayayenza baze bayikhuphe ngqo egazini. Ukusuka apho, uhambo lwayo olubalulekileyo luqala.

Yintoni eyenziwa yi-cholecystokinin emizimbeni yethu?

Kulapho ke kwenzeka khona umsebenzi wokwenyani emva kokuba i-cholecystokinin ingene egazini. Ayihlali nje apho. Ihamba ngegazi, iye kwilungu ngalinye, kwaye yenza imisebenzi emininzi ebalulekileyo.

Oko ikwenzayo ngexesha lokugaya ukutya

Makhe sibone ukuba ibaluleke kangakanani indima edlalwa yi-cholecystokinin ekugayweni kokutya:

• Ibangela ukuba inyongo ifinyele: Ixelela inyongo yakho ukuba, "Kulungile, ngoku unenyongo ngaphakathi kuwe."Faka enye emathunjini amancinci. Lixesha lokuba uqale ukusebenza!" Musa ukumangaliswa, igama elithi 'cholecystokinin' lithetha 'ukuhambisa inyongo'. Le nyongo yiyo enceda ekunyibilikiseni iioyile, okanye amafutha, esiwatyayo, size siwaqhekeze abe ngamathontsi amancinci. Njengokuba sisebenzisa isepha ukuhlamba izitya.
• Ivuselela i-pancreas: Ikwathumela isignali kwi-pancreas, isithi, "Kufuneka uthumele nee-enzymes zakho zokugaya ukutya emathunjini amancinci. Kukho umsebenzi omkhulu ekufuneka wenziwe apha." Elinye igama, "i-pancreozymin," livela kulo msebenzi unxulumene ne -pancreas .
• Ukuqhekeka kweeproteni kunye namafutha: Inyongo evela kwinyongo kunye nee-enzymes ezivela kwi-pancreas zisebenza kunye ukuqhekeza iiproteni kunye namafutha ekutyeni esikutyayo zibe ziingceba ezincinci ukuze zifunxwe ngumzimba. Oku kufana nokuqhekeza ilitye elikhulu libe ziingceba ezincinci.
• Ilawula ukukhupha ukutya esiswini : Ngelixa lo msebenzi usenzeka emathunjini amancinci, i-cholecystokinin ixelela isisu, "Ungakhathazeki, linda umzuzu. Musa ukuthumela ibhetshi entsha yokutya emathunjini amancinci de kube ukutya kwangaphambili kugayiwe." Oku kubizwa ngokuba yi -gastric emptying suppression . Oku kuthetha ukuba emathunjini amancinci akafumani ukutya okuninzi ngaxeshanye, kodwa unexesha lokukugaya ngokufanelekileyo.
• Inciphisa inkanuko : Ngexesha lokugaya ukutya, i-cholecystokinin yenza isisu sethu sizive sigcwele. Ikwavuselela imithambo-luvo yesitho sangasese eludongeni lwesisu, ithumela umyalezo engqondweni othi, "Kwanele, ndihluthi, ungaphindi utye." Yiyo loo nto siziva sigcwele emva nje kokutya.
• I-Peristalsis iqala: Okokugqibela, oku kutya kugayiweyo kufuneka kuhanjiswe emathunjini . Oku kuncedwa kukuqina okune-rhythm kunye nokukhululeka kwemisipha emathunjini, ebizwa ngokuba yi-peristalsis . Kufana nokutyhala ukutya emathunjini .

Khawuthelekelele indlela le hormone inye enceda ngayo inkqubo yethu yokugaya ukutya isebenze kakuhle!

Iziphumo kwingqondo nakwinkqubo yemithambo-luvo

Ukongeza ekuncedeni ekugayweni kokutya, i-cholecystokinin ikwafunyenwe ukuba idlala indima kwingqondo yethu nakwinkqubo yemithambo-luvo ephakathi. Oku kusaphandwa, kodwa oko kufunyenweyo ukuza kuthi ga ngoku kubaluleke kakhulu. Ngokukodwa, inokunceda ekuxhalabeni nasekuxinezelekeni.Kubonakala ngathi inxulunyaniswa neemeko zempilo yengqondo ezifana nokuhlaselwa luloyiko . Ezinye izifundo zibonise ukuba amanqanaba aphezulu e-cholecystokinin engqondweni anyusa ixhala. Oku kunzima kancinci, kodwa kuyacaca ukuba kukwachaphazela nolawulo lwethu lweemvakalelo. Kukwaxelwe ukuba kubandakanyekile ekulawuleni ubushushu bomzimba, okanye ukuguquguquka kobushushu . Kuthiwa ukuba ifakwe engqondweni, iya kubangela umkhuhlane, kwaye ukuba ifakwe kwezinye iindawo zomzimba, iya kubangela i-hypothermia, imeko apho ubushushu bomzimba buyehla. Nangona kunjalo, kufuneka uphando olongezelelweyo ukuze kuqondwe oku ngokuchanekileyo.

Ifumaneka phi i-cholecystokinin emizimbeni yethu?

Njengezinye iihomoni, i-cholecystokinin ihamba emizimbeni yethu yonke egazini lethu. "Ithetha" namalungu ahlukeneyo ngee -receptors ezikhethekileyo kwiiseli zala malungu. Ezi receptors zifana neengcango. Kuphela xa isitshixo esibizwa ngokuba yi-cholecystokinin sikhona apho iingcango zivuleka khona, kwaye emva koko iseli ifumana umyalezo. Kwinkqubo yethu yokugaya ukutya, ii-receptors ze-cholecystokinin (CCK) zifumaneka kwimisipha yenyongo, ulwelwesi lwesisu namathumbu, kunye ne-pancreas. Ezi receptors zinokufumaneka nakwiindawo ezahlukeneyo zobuchopho kunye nenkqubo ye-nervous central.

Ziziphi izifo ezinxulumene ne-cholecystokinin?

Kukho izifo ezithile apho kufunyenwe khona amanqanaba aphantsi e-cholecystokinin. Nangona kunjalo, akukacaci ukuba oku kungenxa yesifo okanye imbangela yesifo. Uphando lusaqhubeka ngale nto. Umzekelo, amanqanaba aphantsi e-cholecystokinin anokunxulunyaniswa neemeko ezifana ne -gastroparesis , imeko apho isisu singakhuphi kakuhle kwaye ukutya kubambeke esiswini, kunye ne -biliary dyskinesia, imeko apho i-gallbladder ingasebenzi kakuhle kwaye ingakhuphi i-bile ngokufanelekileyo. Ukongeza, izazinzulu ziphanda indlela umahluko owahlukeneyo kwiijini ezibandakanyekayo ekuvelisweni kwe-cholecystokinin onxulunyaniswa ngayo nezinye iingxaki zokuxhalaba kunye neengxaki ze-metabolic. Olunye uphando lubonisa ukuba olu tshintsho lwe-genetic lunokutshintsha indlela i-cholecystokinin esebenzisana ngayo nengqondo kwaye ilawula iimpawu zokuxhalaba okanye indlala.

Luthini ulwalamano phakathi kwe-cholecystokinin kunye nokukhuluphala?

Ukutyeba kakhulu, okanye ukutyeba kakhulu, yingxaki kubantu abaninzi namhlanje. Izazinzulu zikwaphanda ngokukhutheleyo ukuba kukho unxibelelwano phakathi kokutyeba kakhulu kunye ne-cholecystokinin. Ezinye zeziphumo ziyamangalisa. Umzekelo, kufunyenwe ukuba abantu abanotshintsho oluthile (utshintsho) kwi-gene ye-cholecystokinin banamathuba angama-60% okuba batyebe kakhulu kunabanye. Kukwakho nobungqina bokuba abantu abatyebe kakhulu (udidi lwesithathu lokutyeba), oko kukuthi, abantu abatyebe kakhulu, banobuthathaka kwi-cholecystokinin. Oku kuthetha ukuba nangona bene-cholecystokinin emizimbeni yabo, banokungakwazi ukuqonda ngokufanelekileyo uphawu 'lokuzaliswa' olubanika lona. I-Cholecystokinin isebenza nenye i-hormone ebizwa ngokuba yi-leptin ukulawula indlala. Abantu abatyebe kakhulu banokuba nokungalingani phakathi kwemiqondiso yendlala kunye nokugcwala engqondweni yabo. Ke ngoko, ukuqonda i-cholecystokinin kunokunceda ekufumaneni unyango lokutyeba kakhulu.

Yintoni le cholecystokinin test?

Uvavanyo lwe-cholecystokinin lubandakanya ukunika inyongo yakho iyeza elibizwa ngokuba yi-cholecystokinin ukuze liyivuselele ukuba inciphe. Ngamanye amaxesha oku kwenziwa njengenxalenye ye -HIDA scan, oluluhlobo olukhethekileyo lovavanyo lokubona amayeza enyukliya . Musa ukothuka ligama, olu luvavanyo olukhuselekileyo kakhulu. Nantsi into eyenzekayo: 1. Okokuqala, ingcali ifaka inani elincinci le-radioactive isotope, okanye i-tracer, emthanjeni wakho. Kufana nokupeyinta iindlela ezimbalwa emzimbeni wakho kwaye ijonge okwenzekayo kuzo. 2. Le tracer iya kwisibindi sakho nakwinkqubo ye-biliary (i-gallbladder, i-bile ducts). 3. Emva koko, ikhamera ekhethekileyo (i-scanner) isetyenziselwa ukubamba imitha ekhutshwa yile tracer kwaye ibonise imifanekiso kwiscreen sekhompyutha. Le mifanekiso ivumela ugqirha ukuba abone indlela inyongo eyenziwe ngayo nendlela ehamba ngayo. Ukuba ugqirha wakho ufuna ukubona ukuba kwenzeka ntoni xa inyongo yakho incipha, unokongeza i-cholecystokinin kwi-HIDA scan njengenyathelo elongezelelweyo. Ngelo xesha, ingcali iya kufaka i-cholecystokinin emthanjeni wakho. Emva koko, kuthathwa imifanekiso emininzi. Njenge-cholecystokinin eveliswa ngokwemvelo emathunjini akho, i-cholecystokinin efakwe kwi-injection ivuselela i-gallbladder ukuba ifinyele. Oogqirha bayala olu vavanyo ukuze babone ukuba kukho ingxaki ekusebenzeni kwe-gallbladder yakho kwaye ingaba ikhupha i-bile ngokufanelekileyo na.

Ngaba kukho naluphi na unyango lwe-cholecystokinin?

Okwangoku, akukho nyango lwezonyango olusebenzisa ngqo i-cholecystokinin. Oko kukuthi, i-cholecystokinin ayinikwa njengonyango lwesifo. Nangona kunjalo, isetyenziselwe ukufumanisa nokuvavanya amayeza amatsha. Umzekelo, abaphandi bazama ukwenza amayeza afana ne-cholecystokinin ekunciphiseni ukutya kunye nokunceda ekunciphiseni ubunzima. Kwakhona, i-cholecystokinin inenxalenye ekhethekileyo ebizwa ngokuba yi -CCK-4 . Le CCK-4 yaziwa ngokubangela abantu ukuba bazive bexhalabile kwaye bexhalabile. Ke ngoko, izazinzulu ngamanye amaxesha zisebenzisa i-CCK-4 ukuvavanya ukuba amayeza amatsha okulwa noxinzelelo asebenza kangakanani.

Izinto ezibalulekileyo ekufuneka sizikhumbule (Umyalezo Wokuya Ekhaya)

Ngoko ke, kwinto esithethe ngayo nge-cholecystokinin, ungakhumbula ezinye zezona zinto zibalulekileyo. Ngoku uyaqonda ukuba le hormone incinci yenza umsebenzi omkhulu kangakanani emizimbeni yethu, akunjalo?

• I-Cholecystokinin yi -hormone ebalulekileyo kwinkqubo yokugaya ukutya . "Ithetha" nawo onke amalungu abandakanyekayo ekugayweni kokutya, njenge-gallbladder kunye ne-pancreas, kwaye iwanceda ukuba enze umsebenzi wawo ngokufanelekileyo.
• Oogqirha bayisebenzisa njengesivuseleli esithembekileyo sokuvavanya ukusebenza kwenyongo.
• Ikwanceda ukulawula indlala . Kukwafunyaniswe ukuba ukungasebenzi kakuhle kwe-cholecystokinin kunokunxulunyaniswa neemeko ezifana nokutyeba kakhulu.
• Izazinzulu ziyaqhubeka nokufunda ngendima yayo kwingqondo nakwinkqubo yemithambo-luvo, ingakumbi ulwalamano lwayo neemeko ezifana nokuxhalaba kunye neengxaki zoloyiko.

Ngoko ke, imizimba yethu ngoomatshini abamangalisayo ngokwenene! Kuyamangalisa ukuba ezi zinto zincinci zinokwenza umahluko omkhulu kangakanani kwimpilo yethu, akunjalo? Nyamekela umzimba wakho, kwaye aba bahlobo bancinci baya kukunyamekela!

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I-Cholecystokinin, i-Cholecystokinin, iHormone, ukugaya ukutya, i-Gallbladder, i-Pancreas, indlala, ukutyeba kakhulu, i-HIDA scan