Yintoni i-DHT? Ichaphazela njani umzimba wakho? (i-Dihydrotestosterone)

Ngaba wakha weva nge-DHT okanye i-Dihydrotestosterone ? Mhlawumbi ewe, mhlawumbi akunjalo. Kodwa le yinto ebaluleke kakhulu emzimbeni wethu, ingakumbi kwimpilo yamadoda. Ngoko ke, namhlanje siza kuthetha ngale DHT ngendlela elula onokuyiqonda.

Yintoni i-DHT (i-dihydrotestosterone)? Ngamafutshane...

Ngamafutshane, i-DHT yi-hormone ekhethekileyo enceda ekuphuhliseni iimpawu zesini zamadoda . Uyazi, ii-hormone zifana nezithunywa ezincinci ezilawula yonke imisebenzi emzimbeni wethu. I-DHT ikwayinxalenye yeqela lee-hormone ezibizwa ngokuba yi-Androgen. I-Androgen ligama elinikwa ii-hormone ezibangela iimpawu zamadoda.

Cinga ngayo, i-DHT iqala ukusebenza emzimbeni wendoda ukususela ngexesha esesibelekweni. Emva koko, indima ye-DHT iyatshintsha ngamaxesha ahlukeneyo ebomini bayo. Nangona izazinzulu zingaqinisekanga ukuba i-DHT ibachaphazela njani abafazi, zicinga ukuba inokuchaphazela ukukhula kweenwele emzimbeni nakwiindawo zabucala.

I-androgen ephambili kwindoda endala yi -testosterone . Malunga ne-10% yale testosterone iguqulwa ibe yi-DHT yonke imihla . Le nkqubo yenzeka eluswini olujikeleze izitho zangasese nakwi-prostate gland kumadoda. Kwabasetyhini, oku kwenzeka eluswini. Kwenzeka nakwiindawo ezifana nesibindi sethu. Ngenxa yokuba amadoda ngokwendalo ane-testosterone eninzi emizimbeni yawo, amanqanaba awo e-DHT nawo aphezulu kakhulu.

Yintoni kanye kanye eyenziwa yi-DHT emizimbeni yethu?

I-DHT yenza izinto ezahlukeneyo kumanqanaba ahlukeneyo obomi bendoda. Ibaluleke kakhulu ngexesha lokukhula komntwana ongekazalwa kunye nokufikisa .

Nangona kunjalo, ngokungafaniyo ne-testosterone, i-DHT ayidlali indima enkulu ekugcineni imisebenzi yomzimba kumadoda amadala. Xa ekhulile, i-DHT ibonwa kakhulu kwiimeko ezifana nokukhula kwe-prostate kunye nokulahleka kweenwele zepateni yamadoda.

Indima ye-DHT ngexesha lesigaba sokukhulelwa

Ngethuba esesibelekweni, amalungu esini omntwana akhula abe yindoda okanye abe ngumfazi kuxhomekeke kwindawo ethile yeehomoni. Kwimeko yenkwenkwe, i-DHT isebenza nezinye iihomoni (kuquka ne-testosterone ) ukucinezela uphuhliso lweempawu zesini zobufazi nokukhuthaza uphuhliso lweempawu zesini zobudoda .

I-DHT ibalulekile ekuphuhlisweni kwesini sangaphandle sendoda, ipenis kunye namasende, kwimveku engekazalwa. I-DHT ikwanceda ekuphuhlisweni kwendlala yeprostate.

I-DHT ngexesha lokufikisa

Njengoko inkwenkwe ifikelela kwinqanaba lokufikisa, i-DHT inceda ipenis kunye namasende ukuba akhule ngakumbi. Ayipheleli apho, kodwa i-DHT ikwanoxanduva olukhulu kwezi zinto zilandelayo:

• EbusweniUkukhulisa iindevu.
• Ukukhula kweenwele emzimbeni.
• Ukukhula kweenwele kwiindawo zabucala.
• Ukukhula kweprostate .

Kuza kwenzeka ntoni ukuba amanqanaba e-DHT ayanda?

Ezinye iimeko zempilo zinxulunyaniswa namanqanaba aphezulu e-DHT. Makhe sijonge ukuba zithini na:

• I-Benign Prostatic Hyperplasia (BPH)
• Umhlaza weprostate
• I-Androgenetic alopecia (ukulahleka kweenwele zamadoda )
• I-Polycystic Ovarian Syndrome (PCOS) (kwabasetyhini)

I-Benign Prostatic Hyperplasia (BPH) kunye ne-DHT

I-Benign Prostatic Hyperplasia (BPH) kukwanda kwe-prostate gland yakho. Yimeko eqhelekileyo kakhulu kumadoda angaphezu kweminyaka engama-50 ubudala .

I-prostate gland yakho inokuvelisa i-DHT eninzi. Le DHT ivuselela ukusebenza okuqhelekileyo kwe-prostate gland, kwaye idla ngokubangela ukuba i-prostate gland ikhule. Le BPH inokubangela iingxaki ezifana nobunzima bokuchama kunye nokungasebenzi kakuhle ngokwesondo .

Umhlaza weprostate kunye ne-DHT

Abantu abanomhlaza weprostate badla ngokuba namanqanaba aphezulu e-DHT. Umhlaza weprostate unokubangelwa kukwanda komsebenzi we-DHT kwiprostate yakho, kunye notshintsho oluthile lwemfuza olubangela ukuba iiseli zeprostate zikhule ngokungalawulekiyo.

I-Androgenetic alopecia (ukulahleka kweenwele) kunye ne-DHT

I-Androgenic alopecia yinto esiyibiza ngokuba yi-pattern baldness yamadoda . Kule meko, iinwele ziyawa ukusuka phezulu nangaphambili kwentloko. Ekuhambeni kwexesha, umgca weenwele uyaphela.

Esinye isizathu sokulahleka kweenwele kukwanda komsebenzi we-DHT kwiifollicles zakho zeenwele. Kukho ezinye izizathu, ezifana nefuthe lemfuza. Xa amanqanaba e-DHT esanda, iifollicles zeenwele ziyancipha, umjikelo wokukhula kweenwele uyancipha, kwaye ekugqibeleni iinwele ziyawa.

I-PCOS kunye ne-DHT

I-Polycystic Ovarian Syndrome (PCOS) kukungalingani kwamahomoni okuchaphazela abasetyhini. Kwenzeka xa ama-ovari abo evelisa iihomoni ezininzi ze-androgen, kuquka ne-testosterone. Oku kukhokelela kumanqanaba aphezulu e-DHT. Oku kunokubangela iimpawu ezahlukeneyo, kuquka ukuya exesheni okungaqhelekanga, ukukhula kweenwele emzimbeni ngokugqithisileyo (i-hirsutism), kunye ne-acne .

Kuza kwenzeka ntoni ukuba amanqanaba e-DHT ehla?

Ezinye iimeko zinxulunyaniswa namanqanaba aphantsi e-DHT. Makhe sijonge ukuba zithini na:

• Ukunqongophala kwe-5-alpha reductase `(ukunqongophala kwe-5-alpha reductase)`
• I-testosterone ephantsi / i-hypogonadism yamadoda

Amanqanaba aphantsi kunesiqhelo e-DHT achaphazela kakhulu amadoda. Ezinye izazinzulu zikholelwa ukuba amanqanaba aphantsi e-DHT kumantombazana anokulibazisa ukufikisa.

Ukungabikho kwe-5-alpha reductase kunye ne-DHT

I-5-alpha reductase yi-enzyme enceda ukuguqula i-testosterone ibe yi-DHT. Utshintsho lwemfuza oluchaphazela ukuveliswa kwale enzyme lunokubangela ukuba amanqanaba e-DHT abe phantsi okanye angabikho. Oku kubizwa ngokuba yi-5-alpha reductase deficiency. Le yimeko ezuzwe ngabazali kubantwana (i-autosomal recessive pattern) .

Ukunqongophala kwe-5-alpha reductase kuchaphazela uphuhliso lwezesondo lweemveku ezingamadoda ngokwemfuza (ezo zine-XY chromosomes). Iintsana ezingamadoda ezizelwe zine-le ngxaki zihlala zibonisa ezi mpawu zilandelayo:

• Izitho zangasese zangaphandle azikakhuli ngokupheleleyo.
• Ubukho bamasende asebenzayo emzimbeni (awaphumi).
• Indlala yeprostate encinci okanye engekhoyo.

Kubalulekile: Kwiimeko ezinzima zokungabikho kwe-5-alpha reductase, iintsana ezingamaduna ezine-genesis ezinee-chromosomes ze-XY zinokuba nee-genitalia zangaphandle zabasetyhini. Nangona kunjalo, i-DHT enciphileyo ayichaphazeli uphuhliso lwama-testicles (asenokuvelisa isidoda) kunye ne-internal genitalia. Oku kwahlukile kwimeko ebizwa ngokuba yi-Androgen Insensitivity Syndrome. Abantu abanale meko banama-testicles aqhelekileyo kunye namanqanaba aqhelekileyo okanye aphezulu e-testosterone, kodwa abanazo ii-receptors ze-androgen, ngoko ke abazikhulisi iimpawu zesondo zesibini, kwaye abachumi kangako.

Amakhwenkwe anesifo sofuzo i-5-alpha reductase deficiency awabi naboya ebusweni xa efikelela ebusheni. Nangona kunjalo, imizimba yawo isavelisa i-testosterone, nto leyo ekhokelela kwizinto ezifana nelizwi elinzulu, ukukhula kwemisipha, kunye nokwanda kwepenis.

Amanqanaba aphantsi e-testosterone kunye ne-DHT

I-Testosterone emzimbeni wakho yiyo eguqula ibe yi-DHT. Ngoko ke, ukuba amanqanaba akho e-testosterone aphantsi, amanqanaba akho e-DHT nawo aya kuba phantsi kunesiqhelo. Elinye igama lamanqanaba aphantsi e-testosterone yi-hypogonadism yamadoda.

Kukho iintlobo ezimbini eziphambili ze-hypogonadism yamadoda: i-classical (ekhoyo ekuzalweni okanye kamva ebomini) kunye ne-late-onse. Ngokuxhomekeke kwiminyaka yakho, i-hypogonadism yamadoda inokubangela iingxaki ezahlukeneyo.

Ngaba kufuneka ndidibane nogqirha malunga namanqanaba am e-DHT?

Ukuba ucinga ukuba wena okanye umntwana wakho unokuba nesifo esibangelwa yi-DHT ephantsi okanye ephezulu, qiniseka ukuba uthetha nogqirha.Emva koko angenza uvavanyo olufunekayo okanye akuthumele kumntu ochwephesha kwinkqubo ye-endocrine, njengogqirha we-endocrinologist.

I-Dihydrotestosterone, okanye i-DHT, ibalulekile ekukhuleni ngokwesondo kwamadoda. Kodwa ukuba amanqanaba ayo aphezulu kakhulu okanye aphantsi kakhulu, inokubangela iingxaki ezifana nokukhula okungaphelelanga kwesini sangaphandle, ukwanda kwe-prostate, kunye nokulahleka kweenwele. Ukuba unenkxalabo malunga namanqanaba akho e-DHT, ungathandabuzi ukuthetha nogqirha wakho. Banokwenza uvavanyo kwaye bacebise unyango olunokukunceda.

Izinto ezibalulekileyo ekufuneka uzikhumbule kweli nqaku (Umyalezo Wokuya Ekhaya)

• I-DHT yi-hormone ye-androgen enceda kakhulu ekuphuhliseni iimpawu zesini zamadoda .
• I-DHT ibalulekile ekuphuhlisweni kwamalungu esini angaphandle endoda ngexesha lesigaba somntwana ongekazalwa kunye nokukhula kweenwele zobuso kunye neenwele zomzimba ngexesha lokufikisa.
• Amanqanaba aphezulu e-DHT angakhokelela kwiimeko ezifana ne-benign prostatic hyperplasia (BPH), umhlaza we-prostate, ukulahleka kweenwele kumadoda, kunye ne-PCOS kubasetyhini.
• Ukuba amanqanaba e-DHT aphantsi, iimeko ezifana nokungabikho kwe-5-alpha reductase zinokuchaphazela ukukhula kwesondo samadoda.
• Ukuba unamathandabuzo okanye uxhalabile malunga namanqanaba akho e-DHT, kungcono ukufuna ingcebiso kagqirha .

Ndiyathemba ukuba ngoku uyiqonda ngcono i-DHT. Ukwazi izinto ezinje kubaluleke kakhulu kwimpilo yakho!

I- DHT, i-dihydrotestosterone, iihomoni, impilo yamadoda, i-testosterone, i-prostate, ukulahleka kweenwele, i-PCOS