Ngaba ngamanye amaxesha ukhe uzive uvuvukile ngequbuliso emzimbeni wakho? Kusenokuba yi-angioedema!

Ngaba wakha waphawula ukuba imilebe yakho idumba ngequbuliso, okanye amehlo akho aziva evuvukile? Ngamanye amaxesha ubuso bakho bonke, kwanezandla neenyawo zakho, ziyadumba. Kuqhelekile ukuba uzive usoyika kancinci xa kwenzeka into efana nale. Ixesha elininzi, oku kubangelwa yimeko ebizwa ngokuba yi-angioedema . Makhe sithethe ngale nto ngokweenkcukacha, ngokulula, kulungile?

Yintoni i-Angioedema? Masiyiqonde ngokulula!

Ngamafutshane, i-Angioedema kukudumba kwezicubu ezingaphantsi kolusu lwethu, ingakumbi i-dermis, umaleko wangaphakathi wolusu, okanye iileya ezingaphantsi kwe-mucous membrane. Oku kwenzeka njengempendulo kwinto ethile. Usenokuba ukhe weva ngemeko ebizwa ngokuba yi-urticaria , okanye ii-hives . I-Angioedema kunye nee-hives zihlala zisenzeka kunye, kwaye izizathu ziyafana kakhulu. Kuzo zombini iimeko, ulwelo luvuza kwimithambo yethu emincinci yegazi luye kwizicubu, nto leyo ebangela ukuba iindawo zidumbe.

I-Angioedema idla ngokuqala ngequbuliso ize iphele kusuku olunye okanye ezimbini. Ichaphazela kakhulu imilebe kunye namehlo . Kodwa, khawucinge, ukuba oku kudumba kuchaphazela iindlela zethu zomoya , kunokuba yingozi kakhulu, kude kube yingozi nakubomi . Ngoko ke kufuneka silumke nangalo nto.

Ziziphi iintlobo eziphambili ze-angioedema?

Kukho iintlobo ezahlukeneyo ze-angioedema. Imibutho eyahlukeneyo yezempilo inokuzihlela ngokwahlukeneyo, kodwa ngokubanzi, singazichonga iintlobo ezininzi eziphambili.

1. I-angioedema ebukhali ye-allergy

Mhlawumbi olu lolona hlobo uluvileyo nolunamava alo kakhulu. Luyenzeka xa ujongene nento onayo i-allergy . Oku kungaba yinto oyityileyo (ukutya, isiselo), usele amayeza, okanye uyichukumisile (umzekelo, into eyenziwe nge-latex yerabha yendalo). Lunokwenzeka nasemva kokuba ulunywe sisinambuzane okanye sisigcawu.

I-angioedema ebukhali ye-allergy yenzeka ngokukhawuleza kakhulu , ngesiqhelo kwimizuzu embalwa ukuya kwiyure okanye ezimbini, emva kokudibana ne-allergen. Oku kudumba kudla ngokuhamba nee-hives.

2. I-Angioedema ebangelwa yimpendulo yeziyobisi engeyiyo i-allergy

Olu hlobo lwe-angioedema alubonakali kwangoko emva kokuba usele amayeza. Udidi oluphambili lwamayeza abangela le mpendulo ingenalo i-allergy zii -angiotensin-converting enzyme inhibitors , okanye ii-ACE inhibitors okanye ii-ACEIs ngamafutshane.La mayeza asetyenziswa kakhulu ukwandisa imithambo yegazi, ukunyanga iingxaki zentliziyo, kunye nokunciphisa uxinzelelo lwegazi oluphezulu. Amayeza angengo-steroidal anti-inflammatory (NSAIDs) , afana ne -ibuprofen kunye ne -naproxen, nawo anokubangela olu hlobo lwe-angioedema.

3. I-Angioedema yesizathu esingaziwayo (i-Idiopathic angioedema)

Igama elithi " idiopathic" lithetha "isizathu esingaziwayo." Ngoko ke kunzima ukufumana unobangela othile wolu hlobo lwe-angioedema. Ukudumba kudla ngokuvela ebusweni, ezingalweni, esiqwini nasemilenzeni. Abanye abantu banokuba neengxaki zenkqubo yomzimba yokuzikhusela kunye noxinzelelo.

4. I-angioedema yelifa (HAE)

Le yi -angioedema yelifa , eyaziwa ngokuba yi -HAE ngamafutshane. Le yinto oyifumana kubazali bakho ngee-genes zakho. Abantwana banokuyizuza nokuba ngumzali omnye kuphela one-gene, okanye nokuba banesi sifo. Abanye abantu banokukhula nolu hlobo lwe-angioedema ngenxa yotshintsho lwe-genetic oluzenzekelayo. Kuqikelelwa ukuba malunga nomntu omnye kwabangama-50,000 unokuba nolu hlobo lwe-angioedema yelifa (HAE). Kukho iintlobo ezintathu eziphambili zale nto, nganye kuzo inxulumene ngandlel’ ithile namanqanaba e -C1 protein kunye/okanye i-C1 esterase inhibitor egazini lethu.

5. Ukungabikho kwe-C1 inhibitor deficiency angioedema

Oku kukwabangela i-angioedema, kodwa ayilofuzo. I-Acquired ithetha ukuba awuzalwanga une-deficiency, kodwa uyayikhula kamva ebomini. Njengezinye iintlobo, olu hlobo lwe-angioedema lunokuchaphazela i-larynx yakho, okanye i-windpipe, kwaye lunokubangela i-asphyxiation. Ukuba unemeko efana ne -B-cell lymphoma, le meko ibizwa ngokuba yi-Acquired C1 inhibitor deficiency.

6. I-Angioedema ebangelwa kukungcangcazela (i-Vibratory angioedema)

Kule meko, ukudumba kubangelwa kukungcangcazela okuqhubekayo. Umzekelo, oku kunokwenzeka xa ukhwela ibhayisekile, ubaleka, ugijima, ufumana i-massage enamandla, okanye wenza eminye imisebenzi efanayo. I-vibratory angioedema lolunye uhlobo lwesimo esingaqhelekanga esibizwa ngokuba yi-chronic inducible urticaria . Kuyo, kuvela amaqhuqhuva ngenxa yezinto zangaphandle ezifana nokubanda, ubushushu, amanzi, uxinzelelo, okanye ukungcangcazela. Ukuqaqamba okurhawuzelelayo kuyaqhubeka kwaye kuhlala malunga neeveki ezintandathu.

Ngubani onokuthi abe ne-angioedema?

Enyanisweni, nabani na unokuba ne-angioedema. Kuqikelelwa ukuba phakathi kwama-20% nama-25% abantu baseMelika baya kuba ne-angioedema kunye/okanye i-urticaria ubuncinane kanye ebomini babo. Ngoko ke le meko ixhaphakile naseSri Lanka.

Zithini iimpawu ze-angioedema? Uzibona njani?

Iimpawu eziphambili ze-angioedema zezi:

• Ukudumba okanye ukudumba kobuso , ingakumbi kufutshane namehlo nomlomo, kuquka imilebe nolwimi. Khawuthelekelele uvuka kusasa uze ngequbuliso imilebe yakho idumbe kangangokuba uzive ngathi kunzima ukuthetha.
• Ukuba amathumbu akho ayavuvukala, unokuba neengxaki zokugaya ukutya . Oku kuquka iintlungu zesisu, urhudo, isicaphucaphu, kunye nokuhlanza.
• Ukudumba kwezandla, iinyawo, okanye iindawo zangasese.
• Utshintsho kuxinzelelo lwegazi lunokubangela izinto ezifana nesiyezi okanye ukuquleka .
• Ukudumba komlomo, umphimbo, okanye iindlela zomoya kunokwenza kube nzima ukuphefumla nokuthetha. Le yeyona nto iyingozi kakhulu. Ukuba kwenzeka into efana nale, yingxaki yezonyango. Kufuneka uye esibhedlele ngoko nangoko!

Okona kubaluleke kakhulu: Ukuba umphimbo wakho uyavuvukala kwaye uzive ngathi unengxaki yokuphefumla, ayisiyonto ihlekisayo. Funa ingcebiso kagqirha ngoko nangoko.

Kutheni kukho i-angioedema? Zithini izizathu?

Izizathu ze-angioedema ziyahluka ngokuxhomekeke kuhlobo lwe-angioedema onayo. Nangona kunjalo, eyona nto ixhaphakileyo yi-allergies . Kukho iintlobo ezininzi ze-allergies ezinokubangela oku:

• Ukunganyamezelani nokutya: Ubisi, amaqanda, amantongomane afana ne-cashews, kunye nokutya kwaselwandle okufana ne-shellfish zizinto ezibangela oku.
• Ukunganyamezelani namayeza: Amayeza okubulala iintsholongwane afana ne-penicillin kunye namayeza e-sulfa, amayeza angengo-steroidal anti-inflammatory (NSAIDs), kunye ne-contrast media ezisetyenziswa kwezinye iimvavanyo zomfanekiso zinokubangela oku. Olu hlobo lwe-allergies lunokubangela amaqhuqhuva.
• Ityhefu: Ityhefu ekhutshwa kukulunywa zizinambuzane, kwaye ayifumaneki rhoqo zizilwanyana ezifana nesigcawu esimdaka esihlala sihleli.
• I-latex yerabha yendalo: I-Latex yinto esetyenziselwa ukwenza izinto ezifana neeglavu, iibhaluni, iikhondom, kunye nee-catheter zonyango. Ugqirha wakho usenokuba ukubuzile ukuba ngaba une-allergy kwi-latex.

Ezinye izizathu ziquka iingxaki zofuzo kunye neengxaki zamva nje ngeproteni ye-C1 inhibitor, iimpembelelo zamayeza ezenzeka ngaphandle kokurhawuzelelwa okanye ukurhawuzelelwa (ezi azizo ii-allergies eziqhelekileyo), kunye neentshukumo zokungcangcazela.

Ngaba i-Angioedema iyasulela?

Hayi akunjalo kwakona.Awunakufumana i-angioedema komnye umntu, kwaye awunakuyisasaza komnye umntu. Ayisosifo esosulelayo.

Uyixilonga njani i-angioedema? Bakhangela ntoni oogqirha?

Kunokuba nzima ukufumanisa ukuba loluphi uhlobo lwe-angioedema onayo. Ugqirha wakho uza kuqala akuhlole ngokwasemzimbeni, kodwa uninzi lwexesha ukudumba kubonakala lula. Emva koko baza kukubuza imibuzo embalwa:

• Kuqale nini ukudumba?
• Ngaba ukhe watya, wasela, wathabatha, okanye wachukumisa nantoni na ocinga ukuba inokuba yimbangela yeso senzo?
• Ngawaphi amayeza kunye nezongezo ozisebenzisayo ngoku?
• Ngaba ikho into eyenzekileyo ngaphambili?
• Ngaba kukho omnye umntu kusapho lwakho oye wadumba ngolu hlobo?

Ukongeza ekubuzeni le mibuzo, ugqirha wakho unokuyalela uvavanyo lwegazi okanye ulusu ukujonga ukuba akukho allergies , okanye uvavanyo lwegazi ukujonga i-angioedema enxulumene neproteni ye-C1 inhibitor.

Ziziphi iindlela zonyango lwe-Angioedema?

Unyango lwe-angioedema luyahluka ngokuxhomekeke kuhlobo onalo.

• Xa kukho iimpembelelo ezimbi kakhulu kwi-allergy , ugqirha wakho angakunika inaliti ye-epinephrine onokuyijova ngamaxesha onke. Ufanele uzinike le naliti xa ufowunela ku-911 (1990 eSri Lanka) xa kukho imeko engxamisekileyo.
• Kwi -angioedema ye-allergy , ugqirha wakho unokukunika ii-antihistamines okanye ii-steroids . Ezi zinokuthathwa njengeepilisi, njengolwelo (lomlomo), okanye zinikwe ngemithambo.
• Ukuba une-allergy yeziyobisi , ugqirha wakho uya kufumana enye indlela efanelekileyo endaweni yeyeza elibangela ukudumba. Ungaze uyeke ukuthatha amayeza akho ngaphandle kwengcebiso kagqirha wakho.

Amayeza asekhaya aquka ukusebenzisa umkhenkce ukunciphisa ukudumba, ukuhlamba ngamanzi abandayo, kunye nokusebenzisa ilaphu elipholileyo nelimanzi kwindawo evuvukileyo. Ezi zinokusebenza kakuhle ekudumbeni okukhoyo, ukudumba kuyo yonke imilebe, okanye kwamehlo avuvukileyo.

Ukuba une -angioedema yelifa, i-idiopathic, okanye i-acquired C1 inhibitor deficiency angioedema , kusenokwenzeka ukuba uthunyelwe kwingcali. Amanye amayeza asetyenziselwa ukunyanga okanye ukuthintela i-angioedema yelifa (HAE) aquka:

• I-C1 esterase inhibitor (i-recombinant) (iRuconest®)
• Isithinteli se-C1 (somntu) (iBerinert®, iCinryze®, iHaegarda®)
• I-Ecallantide (Kalbitor®)
• I-Icatibant (Firazyr®)
• ILanadelumab (Takhzyro®)
• I-Berotralstat (Orladeyo®)

Ngaba kukho iindlela zokuthintela i-angioedema?

Ewe, kukho iindlela ezithile.

• Ukuba une -angioedema enxulumene nokunganyamezelani komzimba , ungayithintela ngokuphepha ukutya, amayeza, okanye ezinye izinto (izinto ezibangela ukuba unganyamezelani umzimba).
• Ukuba ufumana i-angioedema engeyiyo i-allergy ngelixa usebenzisa amayeza e-ACEI (ACE inhibitors) , kufuneka uthethe nogqirha wakho malunga nokutshintshela kwenye iyeza.

Yintoni enokulindelwa ngumntu one-angioedema?

Uninzi lweemeko ze-angioedema azihlali ixesha elide . Zihlala ziphela ngokwazo. Nangona kunjalo, kwiimeko ezinzima, unyango luyadingeka ukuze kugcinwe indlela yomoya ivulekile.

Ngaba i-Angioedema ingabulala? Ngaba oku kuyingozi?

Kwabanye abantu, i-allergy angioedema inokukhokelela kwimeko ebizwa ngokuba yi -anaphylaxis - ukudumba okukhulu kweendlela zomoya kunye nemiphunga. Oku kunokuba yingozi ebomini . Oogqirha bacebisa abantu abanale meko ukuba baphathe i-epinephrine ejoyiweyo (i-EpiPen®, i-Auvi-Q®, i-Adrenaclick® kunye nezinye iimpawu) ukunyanga ii-allergy ezinzima.

Nokuba yintoni na imbangela, i-angioedema echaphazela indlela yomoya ihlala ingxamisekile kwezonyango. Ke ngoko, kufuneka unyango olukhawulezileyo. Ngamanye amaxesha, inkqubo yotyando ebizwa ngokuba yi-tracheostomy (ukudala umngxuma kumphimbo womoya) inokufuneka ukunceda ekuphefumleni.

Ukuba ndine-angioedema, ndingazinyamekela njani?

Ukuba une-angioedema, kufuneka uziphephe izinto ezibangela i-allergy . Ukuba ugqirha wakho unika amayeza okuthintela ezinye iziqendu, wasele njengoko kuyalelwe. Ukuba uxelelwe ukuba uphathe i-epinephrine efakwe kwi-ejekti , qiniseka ukuba uhlala unayo. Fundisa usapho lwakho kunye nabahlobo indlela yokuyisebenzisa.

Ndifanele ndimbone nini ugqirha?

Ukuba une-allergy enkulu kwaye ukudumba kuchaphazela iindlela zakho zomoya, fowunela ku-1990 (inkonzo ye-ambulensi yongxamiseko) ngoko nangoko.

Kwiimeko ezingezizo eziqatha kangako, ukuba uyaqhubeka nokuba ne-angioedema, bona ugqirha wakho. Banokuxoxa ngeendlela zokuthintela. Ezinye iindlela zonyango ziquka ii-antihistamines zomlomo kunye nee-steroids. Idiopathic, kunzima ukunyangaAbanye oogqirha basebenzise i-antibody ye-monoclonal ebizwa ngokuba yi-Omalizumab (Xolair®) kwi-angioedema (idiopathic angioedema).

Okokugqibela, ezona zinto zibalulekileyo ekufuneka uzikhumbule

Ukuba amehlo akho, imilebe, okanye izandla zakho ziziva zidumbile, isenokuba yimpendulo yolusu ebizwa ngokuba yi-angioedema. Oku kunokwenzeka ngakumbi ukuba unesifo se-allergies. Gcina irekhodi lokuba oku kwenzeka nini kwaye ngamaxesha angakanani, kwaye ufunde ukuphepha izinto onayo i-allergy kuzo. Ukuba uyazi ukuba abanye abantu kusapho lwakho baye baba nale miphumo, xelela ugqirha wakho. Angacebisa uvavanyo ukuze abone ukuba imeko iyasebenza na kusapho lwakho. Ukuba une-angioedema ngenxa ye-allergy, kubaluleke kakhulu ukugcina i-epinephrine ejovayo kufutshane, njengoko ukudumba kwindlela yakho yomoya kunokubangela ukuba uyeke ukuphefumla. Musa ukoyika, kodwa kububulumko ukuqaphela oku kwaye uthathe amanyathelo afunekayo.

I- Angioedema, ukudumba, ii-aleji, izifo zolusu, unyango olungxamisekileyo, i-epinephrine, i-urticaria