Kuqhelekile ukuba igazi lijike lize liyeke ukopha xa sifumana ukwenzakala. Enyanisweni yindlela yokuzikhusela emzimbeni wethu. Nangona kunjalo, ukuba amajike egazi ahlala ekhula kwimithambo yomzimba ngaphandle kwesizathu, yinto exhalabisayo. Ingakumbi ukuba uhlala uphuphuma isisu ngexesha lokukhulelwa, unobangela usenokuba yile meko ibizwa ngokuba yi-Antiphospholipid Syndrome (APS), esiza kuthetha ngayo namhlanje.
Yintoni i-APS ngokulula?
Ngamafutshane, i-Antiphospholipid Syndrome (APS) yimeko eyenza umzimba wakho ube namathuba amaninzi okwenza amahlwili egazi kunokuba kuqhelekile. Oogqirha ngamanye amaxesha bayibiza ngokuba yi-Antiphospholipid antibody syndrome.
Ezi gazi zibangela iingxaki ezinkulu nezisongela ubomi, ezifana nesifo sohlangothi . Le meko ikwanyusa umngcipheko wokuphuma kwesisu nezinye iingxaki ngexesha lokukhulelwa.
I-APS sisifo esihlasela umzimba . Khawuthelekelele, sinenkqubo yokuzikhusela emzimbeni wethu njengomkhosi. Siyibiza ngokuba yinkqubo yokuzikhusela. Umsebenzi wayo kukusikhusela kwiintsholongwane kunye nezifo ezibangela izifo. Kodwa kwesi sifo esihlasela umzimba, okwenzekayo kukuba inkqubo yethu yokuzikhusela iqala ngempazamo ukuhlasela iiseli ezilungileyo emzimbeni wethu.
Zithini iimpawu zale meko?
Abanye abantu abane-APS banokuba namabala amnyama eluswini lwabo abonakala ngathi yinethi. Oku kubizwa ngokuba yi-livedo reticulitis ngokwezonyango. Nangona kunjalo, uninzi lwabantu abane-APS abanazo iimpawu de babe negazi elijiyileyo okanye babe neengxaki ngexesha lokukhulelwa.
Ezi ziimpawu ezinokwenzeka xa igazi liqhekeka. Kufuneka uzilumkele kakhulu ezi mpawu.
| Uphawu | Inkcazo |
|---|---|
| Iintlungu zesifuba | Ingabangelwa kukuqhekeka kwegazi entliziyweni okanye emiphungeni. |
| Ubunzima bokuphefumla (ukuphelelwa ngamandla) | Ingabangelwa, ngakumbi, kukuqhekeka kwegazi emiphungeni (pulmonary embolism). |
| Intloko ebuhlungu rhoqo | Kusenokuba kukho ingxaki ngemithambo yegazi ekhokelela ebuchotsheni. |
| Intlungu ekhawulezileyo | Intlungu ekhawulezileyo ezingalweni, emilenzeni, emqolo, entanyeni, okanye emhlathini. |
| Ukudumba okanye ukubomvu | Ingabangelwa kukuqhekeka kwegazi, ingakumbi engalweni okanye emlenzeni. |
| Isisu esibuhlungu | Ingabangelwa kukuqhekeka kwegazi kwimithambo yegazi ehambisa igazi kwizitho zesisu. |
Okubaluleke kakhulu: Ihlwili legazi yimeko engxamisekileyo esongela ubomi. Ukuba unesikrokro sokuba unehlwili legazi, yiya kwicandelo lezonyango ezingxamisekileyo lesibhedlele (ETU) elikufutshane ngoko nangoko.
Ukongeza kwezi mpawu, i-APS inokubangela ezinye iimpawu esingenakuzibona okanye esingenakuziva.
- Ukwehla kwamanqanaba eeplatelet egazini.
- I-anemia.
- Ukungasebenzi kakuhle kwevalvu yentliziyo.
Kutheni oku kusenzeka?
I-Antiphospholipid Syndrome yenzeka xa inkqubo yakho yomzimba iqala ngempazamo ukwenza uhlobo olungaqhelekanga lwe-antibody. Ngokwesiqhelo, ii-antibodies ziiproteni ezikhethekileyo ezifuna kwaye zitshabalalise iintsholongwane kunye ne-allergens ezingena emizimbeni yethu. Zifana neerobhothi zokuzikhusela.
Kodwa kumntu one-APS, la ma-antibodies, enziwa yinkqubo yomzimba yokuzikhusela, ahlasela iiproteni ezinamathele kwi -phospholipids (uhlobo lwamafutha) kwiiseli zethu. Olu hlaselo lonakalisa ii-phospholipids, nto leyo eyenza ukuba zinamathele kunye kwaye zenze amahlwili egazi.
Kukho iintlobo ezintathu eziphambili zee-antibodies ezinokubangela i-APS:
- I-Lupus anticoagulant
- I-Anticardiolipin
- I-Anti-B2 glycoprotein 1
Umntu one-APS usenokuba nenye, ezimbini, okanye zonke ezintathu zezi antibodies. Kodwa okumangalisayo nangakumbi kukuba abanye abantu banokuba nazo ezi antibodies kodwa bangaze babe neempawu ze-APS. Iingcali azikayazi kakuhle into ebangela ukuba inkqubo yethu yomzimba yokuzikhusela yenze ezi antibodies zingasebenzi kakuhle.
Ngubani osengozini enkulu yokuba nale meko?
Nabani na unokuba ne-APS. Nangona kunjalo, usenokuba sengozini enkulu ukuba:
- Ukuba ungumfazi .
- Ukuba uneminyaka ephakathi kwama -30 nama-40 ubudala.
- Ukuba unezinye izifo ezibangelwa kukuzikhusela komzimba, ezifana ne-lupus okanye i-rheumatoid arthritis.
- Ukuba elinye lamalungu osapho lwakho asondeleyo (abazali, ootatomkhulu noomakhulu) line-APS.
Ziziphi iingxaki ezinokwenzeka ngenxa ye-APS?
I-Antiphospholipid syndrome inokubangela iingxaki ezinkulu, ngamanye amaxesha ezibulalayo. Ezona ngxaki zinzima zenzeka xa igazi liqhekeka kwaye livala imithambo yegazi ehambisa igazi kwizitho ezibalulekileyo zomzimba wakho.
- Ingqondo: ukubetheka
- Intliziyo: Uhlaselo lwentliziyo (i-thrombosis)
- Imiphunga: Ukuvaleka kwemithambo yegazi emiphungeni (i-pulmonary embolism)
- Izintso: Umonakalo kwizintso
Ukuba ukhulelwe, ihlwili legazi elithintela ukuhanjiswa kwezondlo kwi-placenta linokubangela ukuphuphuma kwesisu. Kwakhona kwandisa umngcipheko we- preeclampsia, imeko apho uxinzelelo lwegazi oluphezulu luvela khona ngexesha lokukhulelwa.
I-Catastrophic antiphospholipid syndrome (CAPS) yingxaki engaqhelekanga kodwa enzima ye-APS. Yimeko apho amahlwili egazi akheka khona kwizitho ezininzi zomzimba kangangeentsuku ezithile. Malunga nesiqingatha sabantu abafumana le meko bayafa. Nangona kunjalo, i-CAPS yenzeka kubantu abangaphantsi kwe-1% abane-APS.
I-APS ayidli ngokuchaphazela ubomi bakho. Nangona kunjalo, ukuba ihlwili legazi lonakalisa ilungu elibalulekileyo, ingakumbi kwimeko efana ne-CAPS, linokuba yingozi.
Ugqirha uluchonga njani ngokuchanekileyo olu sifo?
I-APS idla ngokuchongwa emva kokuba igazi liqhekekile okanye emva kokuphuma kwesisu ngokuphindaphindiweyo. Abanye abantu banokuba nee-antiphospholipid antibodies kodwa bangaze babe neempawu.
Ugqirha uza kuqinisekisa ukuba unayo na i-APS ngovavanyo lwegazi . Baza kuthatha isampuli yegazi lakho baze bajonge ukuba kukho iintlobo ezintathu zee-antibodies ezikhankanyiweyo ngaphambili. Ukuqinisekisa isifo, ubuncinane uvavanyo lwegazi olunye kufuneka lube ne-positive izihlandlo ezibini, ngaphezulu kweenyanga ezintathu.
Zithini iindlela zonyango zoku?
Ugqirha wakho uza kucebisa unyango olunciphisa umngcipheko wokuqhekeka kwegazi. Unyango oluqhelekileyo zii-blood thinners, okanye ii-anticoagulants .
| Uhlobo lweziyobisi | Indlela yokusebenzisa nokusebenza |
|---|---|
| Unyango ngokubanzi | |
| I-Heparin | Eli liyeza elifakwa ngemithambo (IV) elinceda ekunyibilikiseni ihlwili legazi ukuba ulaliswe esibhedlele. |
| I-Warfarin | Le yipilisi oyisela ngomlomo. Inciphisa igazi kwaye ithintele ukwakheka kwamahlwili egazi amatsha. |
| I-aspirin | Ugqirha wakho unokucebisa ukuba uthathe i-aspirin enesilinganiselo esiphantsi ukuthintela ukuba igazi lingaqini kwimithambo yakho yegazi. |
| Unyango olusetyenziswa ngexesha lokukhulelwa | |
| I-Enoxaparin | Le yinaliti enikwa phantsi kwesikhumba. Ihlala icetyiswa kunye ne-aspirin enesilinganiselo esiphantsi ukuthintela ukuphuphuma kwesisu. |
| I-immunoglobulin efakwa kwimithambo yegazi (IVIG) | Olu nyango, olufakwa ngemithambo yegazi, lulawula ukusebenza kwenkqubo yomzimba yokuzikhusela komzimba kwaye lunciphisa umngcipheko wokuphuma kwesisu. |
| Ii-Corticosteroids | La mayeza anciphisa ukudumba emzimbeni kwaye alawula ukusebenza ngokugqithisileyo kwenkqubo yomzimba yokuzikhusela. |
Ukuba ukhulelwe, olu nyango lukhuselekile kuwe nakumntwana wakho, ngoko ke akukho mfuneko yokukhathazeka ngalo.
Masiqaphele nemiphumo emibi yemithi yokunciphisa igazi.
Xa uthatha amayeza okunciphisa igazi, umzimba wakho unokuba semngciphekweni wokopha. Ngoko ke kufuneka ulumke kakhulu ngezi mpawu. Ukuba unayo nayiphi na kwezi , thetha nogqirha wakho ngoko nangoko.
- Ukopha ngeentsini okanye empumlweni ngaphandle kwesizathu .
- Ukopha kakhulu kunesiqhelo ngexesha lokuya exesheni.
- Ukuhlanza okubomvu kancinci okanye okunombala wekofu .
- Igazi elibomvu elikhanyayo kwi-tummy okanye i-tarry stool emnyama .
- Intlungu yesisu ebuhlungu okanye intloko ebuhlungu kakhulu .
- Utshintsho olukhawulezileyo embonweni .
- Ukulahlekelwa ngequbuliso ziingalo okanye imilenze .
Izinto ekufuneka uziqwalasele xa uhlala ne-APS
Eyona nto ibalulekileyo xa uphila ne-APS kukuthintela ukuqhekeka kwegazi. Ngenxa yesi sizathu, kubalulekile ukuthatha amayeza okunciphisa igazi ngokuchanekileyo.
Ukongeza, kubalulekile ukulawula ezinye iimeko zempilo ezibangela umngcipheko wokuqhekeka kwegazi. Ukuba unayo nayiphi na kwezi meko, thetha nogqirha wakho kwaye uzilawule:
- Isifo seswekile
- Igazi elonyukayo
- I-cholesterol ephezulu
- Ukutyeba kakhulu
- Ezinye izifo zokuzikhusela komzimba
Ukutshaya kwandisa umngcipheko wokuqhekeka kwegazi, ingakumbi kumntu onesifo esifana ne-APS.
Ngaba kufuneka ulumke ngokutya nokusela?
Abantu abane-APS abadli ngokufuna ukutya okukhethekileyo. Nangona kunjalo, ukuba uthatha iyeza iWarfarin , kufuneka ulumke ngokutya okutyebileyo kwi-vitamin K (imifuno eluhlaza njengespinatshi). Ukutya ukutya okuninzi okutyebileyo kwi-vitamin K ngaxeshanye kunokunyusa umngcipheko wakho wokuqhekeka kwegazi. Ngoko ke cela ingcebiso kugqirha wakho.
Kwakhona, buza ugqirha wakho malunga nokusetyenziswa kotywala. Utywala buyanciphisa igazi, ngoko ke ukudibanisa namayeza okunciphisa igazi kunokunyusa isiphumo.
Ndifanele ndimbone nini ugqirha?
Ukuba uthatha amayeza okunciphisa igazi, kufuneka ubonane nogqirha wakho rhoqo ukuze ahlolwe igazi ukuqinisekisa ukuba amanqanaba akho okujiya kwegazi akwinqanaba elifanelekileyo.
Ukuba unethemba lokukhulelwa, kubaluleke kakhulu ukuthetha nogqirha wakho ngayo kwangethuba uze ufumane ingcebiso.
Ndingaya nini kwiSebe leeNgxamiseko (i-ETU)?
Yiya kwiSebe lezeMpilo eziNgxamisekileyo (ETU) lesibhedlele ngoko nangoko:
- Ndicinga ukuba unegazi eliqhekekileyo.Ukuba kuyenzeka.
- Ukuba kukho naziphi na iimpawu zehlwili legazi ezibonakala.
- Ukuba wopha kakhulu .
Umyalezo Wokuya Ekhaya
- I-Antiphospholipid Syndrome (APS) yimeko eyonyusa umngcipheko wokuqhekeka kwegazi kuba inkqubo yakho yokuzikhusela yomzimba ihlasela umzimba wakho.
- Oku akuyonto yokoyika, kwaye kunokulawulwa kakuhle ngonyango olufanelekileyo (ingakumbi izinto ezinciphisa igazi).
- Nangona ukuphuphuma kwesisu kunye nezinye iingxaki zinokwenzeka ngexesha lokukhulelwa, kunokwenzeka ukuba ubelethe abantwana abasempilweni phantsi kweliso elifanelekileyo lezonyango.
- Ukuba ufumana iimpawu zokuqhekeka kwegazi, ezinje ngeentlungu zesifuba, ubunzima bokuphefumla, okanye ukudumba kwemilenze, cinga ukuba yingxamiseko kwaye uye esibhedlele ngokukhawuleza.
- Kubaluleke kakhulu ukulandela imiyalelo kagqirha wakho ngokuchanekileyo kunye nokuhlolwa rhoqo.
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