Yintoni iChoroid Plexus Carcinoma? Makhe sithethe ngalo mhlaza wobuchopho uyingozi kodwa ungaqhelekanga!

Ngamanye amaxesha, xa sicinga ngezifo ezithwalwa ngabantu esibathandayo, ingakumbi abantwana bethu abancinci, siziva sinomthwalo omkhulu kwaye sisoyika, akunjalo? Namhlanje siza kuthetha ngohlobo lomhlaza wobuchopho olunzima, kodwa olungaqhelekanga . Musa ukoyika ngoko nangoko xa usiva igama lalo. Kuba, ukwazi nasiphi na isifo ngamandla amakhulu okujongana naso. Ngoko ke, masithethe ngokweenkcukacha ngale "Choroid Plexus Carcinoma".

Yintoni iChoroid Plexus Carcinoma?

Ngamafutshane, le `Choroid Plexus Carcinoma` ngumhlaza okhula kwithishu ekhethekileyo ebizwa ngokuba yi`choroid plexus`` ngaphakathi kwengqondo yethu. Khawucinge nje, kukho iindawo ezahlukeneyo kunye neentlobo ezahlukeneyo zethishu ngaphakathi kwengqondo yethu. Le thishu ye`choroid plexus`` ikwiimbobo (``ventricles``) ngaphakathi kwengqondo. Njengebhaluni yamanzi, yile thishu ye`choroid plexus`` enceda kakhulu ekwenzeni ``cerebrospinal fluid`` (``CSF``) ekhusela kwaye yondle ingqondo yethu kunye nomthambo womqolo ohamba ngomqolo.

Le yithumba elibi . Oku kuthetha ukuba iiseli ezikuyo zikhula ngokungalawulekiyo, ngokukhawuleza kakhulu, kwaye zinokusasazeka kwezinye iindawo. Oogqirha bakwabiza le nto ngokuba yi-"grade 3 choroid plexus tumor." Ezi zikhula ngokukhawuleza kwaye zizama ukusasazeka kuyo yonke "inkqubo yemithambo-luvo ephakathi" ("CNS") ngokusebenzisa ulwelo lwe-"CSF". Yingakho ukunyanga ngamanye amaxesha kunokuba nzima kancinci.

Ixhaphake kangakanani le sifo?

Usenokumangaliswa kukuva oku, kodwa esi sifo sibizwa ngokuba yi-'choroid plexus carcinoma' sisifo esingaqhelekanga . Cinga nje, kuzo zonke iintlobo ezili-100 zeethumba zobuchopho, ngaphantsi kwe-1% zii-'choroid plexus tumors'. Kukho iintlobo ezintathu zeethumba ze-'choroid plexus'. Phakathi kwazo, le 'choroid plexus carcinoma' lolona hlobo lomhlaza lungaqhelekanga nolukuphela kwalo, oko kukuthi, uhlobo 'olubi' . Okubuhlungu kukuba, le meko ichaphazela kakhulu iintsana nabantwana abancinci .

Zithini iimpawu zesi sifo? Sizibona njani?

Ngoko ke, zithini iimpawu zale meko? Oku kunokwahluka ngokuxhomekeke kubukhulu bethumba, indawo elikuyo engqondweni, kunye nobudala bomntwana. Kodwa, ngokubanzi, kukho iimpawu ezimbalwa ekufuneka uziqwalasele:

• Ukuhlala uziva udiniwe kakhulu kwaye udiniwe: Kungathi umntwana akasaphili, abagijimi bedlala njengakuqala. Babonakala belele rhoqo.
• Intloko ebuhlungu: Umntwana omncinci usenokungakwazi ukucacisa oku, kodwa singakubona ngezinto ezifana nokubamba iintloko, ukukhala rhoqo, nokwala ukutya.
• Ukucaphuka okanye ukuxakeka: Umntwana omncinci usenokuba nomsindo kwaye kube nzima ukumthuthuzela. Usenokuba nenkani ngakumbi kunangaphambili.
• Isicaphucaphu nokuhlanza: Oku kunokuba kubi ngakumbi, ingakumbi kusasa.
• Ukuba ndindisholo okanye ubuthathaka kwezinye iindawo zomzimba: Ingalo okanye umlenze usenokuvakala ngathi ndindisholo ngokupheleleyo.
• Ukuxhuzula: Ukuxhuzula ngequbuliso kunye nokulahlekelwa zingqondo.
• Iingxaki zokubona: Usenokubona umbono ofipheleyo okanye ubone imifanekiso emibini ngaxeshanye (diplopia). Umntwana omncinci unokuhlikihla amehlo akhe rhoqo okanye abe nobunzima bokugxila.
• Ubungakanani bentloko ekhulisiweyo: Kwiintsana ezincinci, intloko inokukhula njengoko uxinzelelo ngaphakathi kwengqondo lusanda kuba amathambo entloko akadibani ngokupheleleyo.

Musa ukoyika ukuba nesi sifo kuba nje unesinye okanye ezimbini kwezi mpawu. Nangona kunjalo, ukuba ezi mpawu ziyaqhubeka, kulungile ukubona ugqirha .

Kutheni olu hlobo lwesifo lusenzeka? Yintoni unobangela?

Enyanisweni, kunzima koogqirha ukutsho kanye ukuba kutheni abanye abantu benesifo se-choroid plexus carcinoma. Ngokwesiqhelo, naluphi na umhlaza luvela xa kukho utshintsho kwenye yezakhi zofuzo emizimbeni yethu, esizibiza ngokuba yi-mutation. Olu tshintsho lwezakhi zofuzo lubangela ukuba iiseli eziphilileyo zibe ziiseli zomhlaza kwaye zande ngokungalawulekiyo, zikhule zibe yi-tumor, kwaye ngamanye amaxesha zisasazeke emzimbeni wonke.

Ngaba kukho naziphi na izinto ezibangela umngcipheko ezichaphazela oku?

Nabani na anokuba nale meko ibizwa ngokuba yi-'choroid plexus carcinoma'. Nangona kunjalo, kufunyenwe ukuba izinto ezithile (esizibiza ngokuba 'zizinto ezinobungozi') zinokwandisa amathuba okuba nayo. Makhe sibone ukuba zithini:

• I-Aicardi syndrome: Esi sisifo esingaqhelekanga kakhulu esibangelwa yimfuza. Abantwana abazalwa benale meko baneengxaki ezithile ekukhuleni kwengqondo, nto leyo ebenza babe namathuba amaninzi okufumana iithumba ze-choroid plexus. Oku akuqhelekanga ukuba kuzuzwe njengelifa.
• I-Li-Fraumeni syndrome: Le yimeko engaqhelekanga yemfuza. Abantu abanale syndrome banamathuba amaninzi okufumana iintlobo ezahlukeneyo zomhlaza. Oku kudla ngokubangelwa kukutshintsha kwemfuza okudluliselwa kumzali omnye ukuya emntwaneni.
• Isini sebhayoloji: Nangona isizathu esichanekileyo singacacanga, izibalo zibonisa ukuba abafazi banamathuba amancinci okufumana esi sifo.

Oogqirha bayixilonga njani le sifo? (Ukuxilongwa)

Ngoko ke, oogqirha baqinisekisa njani ukuba unayo i-choroid plexus carcinoma? Bakwenza oku ngokumamela ngenyameko iimpawu zakho, benze uvavanyo lomzimba, baze benze iimvavanyo ezahlukeneyo. Ezi mvavanyo zinokwahluka ngokuxhomekeke kwiminyaka yakho, okanye iminyaka yomntwana wakho:

• Uvavanyo lokuqonda: Olu vavanyo luvavanya indlela osebenza kakuhle ngayo, njengenkumbulo, ingqalelo, kunye nokukwazi ukufunda.
• Uvavanyo olupheleleyo lwe-neurological: Olu vavanyo luza kujonga ukubona, ukuva, iingxaki zokulinganisela, ukusabela komzimba, kunye nokulungelelaniswa kwamalungu ahlukeneyo omzimba.
• Iskeni yobuchopho ye-MRI (Magnetic Resonance Imaging) okanye ezinye iimvavanyo zomfanekiso (ezifana ne-CT scan): Olu luvavanyo olubaluleke kakhulu. Lunokubonisa ukuba kukho na iithumba engqondweni, ukuba zikhulu kangakanani, apho zikhoyo, kwaye ingaba kukho na imeko ebizwa ngokuba yi-hydrocephalus (ukuqokelelwa kolwelo lwe-cerebrospinal (CSF) kwimingxuma yobuchopho, okubangela uxinzelelo olongezelelekileyo).
• Uvavanyo lwe-DNA (uvavanyo lwemfuza): Olu vavanyo lungenziwa ukuze kubonwe ukuba kukho naluphi na utshintsho lwemfuza oluhambelana neemeko ezifana ne-Li-Fraumeni syndrome okanye i-Aicardi syndrome ekhankanyiweyo ngaphambili.
• Ukubhoboza umqolo (ukubhoboza i-lumbar): Oku kuquka ukufaka inaliti encinci emqolo ongezantsi kunye nokuthatha isampuli encinci ye-CSF. Emva koko ithunyelwa kwilabhoratri ukuze ivavanywe iiseli zomhlaza.

Zithini iindlela zonyango zoku?

Ukuba kuqinisekisiwe ukuba unethumba elinje, yintoni omawuyenze emva koko? Kukho iindlela ezahlukeneyo zonyango. Eyona iphambili lutyando .

• Utyando: Oogqirha bemithambo-luvo benza utyando lobuchopho ukuze basuse ithumba ngokupheleleyo. Olu lutyando oluntsonkothileyo kakhulu. Iqhekeza elincinci lethumba elisusiweyo (i-biopsy) liyathathwa lize lithunyelwe kwilebhu ukuqinisekisa ukuba yi-choroid plexus carcinoma okanye lolunye uhlobo.

Ukuba olu vavanyo lwe-biopsy luqinisekisa ukuba kukho i-choroid plexus carcinoma, kwaye ithumba alinakususwa ngokupheleleyo, okanye ukuba umhlaza usasazekile, wena okanye umntwana wakho nisenokufuna unyango olongezelelweyo. Oku kuquka:

• Unyango lweKhemotherapy: Oku kuquka ukunika umzimba iintlobo ezahlukeneyo zamayeza okubulala iiseli zomhlaza. La mayeza abulala iiseli zomhlaza ezahlulahlula ngokukhawuleza.
• Unyango ngemitha: Oku kusebenzisa imitha enamandla aphezulu (umz. ii-X-ray) ukujolisa nokutshabalalisa iiseli zomhlaza.

Olunye okanye ngaphezulu kwezi ndlela zonyango lungasetyenziswa kunye. Oku kugqitywa liqela loogqirha abaziingcali, kuthathelwa ingqalelo izinto ezininzi ezifana nemeko yesigulana kunye nohlobo lwethumba.

Ziziphi iingxaki ezinokubakho emva kotyando?

Njengakwezinye iintlobo zotyando, kukho ithuba elincinci leengxaki emva kotyando lobuchopho. Nangona zingaqhelekanga, ezinye zezinto ezinokubonwa ngamanye amaxesha ziquka:

• Ukopha okanye ukudumba engqondweni.
• Ubunzima bokucinga, ukudideka okanye ukuphazamiseka kwengqondo.
• Intloko ebuhlungu engapheliyo.
• Usulelo kwindawo yotyando.
• Ukulahlekelwa yinkumbulo okanye ubunzima bokuthetha.

Oogqirha baza kukwazisa ngezi zinto kwangaphambili.

Ngaba kukho iindlela ezintsha zonyango zesi sifo eziphuhliswayo?

Ewe! Isayensi yezonyango iqhubela phambili imihla ngemihla. Ngoko ke, uphando luyaqhubeka ukufumana unyango olutsha nolusebenzayo ngakumbi lwesi sifo, "i-choroid plexus carcinoma." Ezinye zezi zisenokuba zisekwinqanaba lophando (``uvavanyo lweklinikhi``). Nazi imizekelo embalwa:

• Unyango lwe-Immunotherapy: Le yindlela enomdla kakhulu. Ibandakanya ukuvuselela inkqubo yethu yomzimba yokuzikhusela (inkqubo esikhusela kwizifo) kunye nokuyinika amayeza ayinceda ekufumaneni nasekutshabalaliseni iiseli zomhlaza.
• Unyango olujoliswe kulo: Oku kuquka ukunika amayeza ajolise kutshintsho oluthile lwemfuza olubangela umhlaza kwaye luchaphazela kuphela olo tshintsho. Oku kubangela umonakalo omncinci kwiiseli eziphilileyo.

Ungafunda okungakumbi ngezi ndlela zonyango zintsha ngokuthetha nogqirha wakho.

Kunjani ukuchacha emva konyango?

Ixesha elithathwayo ukuze uphile emva konyango, kuquka nexesha onokubuyela ngalo emsebenzini okanye esikolweni, lixhomekeke kwizinto ezininzi. Nazi ezinye zazo:

• Ubudala bakho kunye nempilo yakho iyonke.
• Indawo ekuyo ithumba, ubungakanani balo, kunye nenani leethumba ezikhoyo.
• Ukuba ufumene unyango olongezelelweyo olufana ne-chemotherapy okanye unyango lwe-radiation, iziphumo zalo.

Ngoko ke, kubalulekile ukulandela imiyalelo kagqirha wakho ngokuchanekileyo . Ukuze bajonge ukuba inkqubo yokuphiliswa ihamba kakuhle na, oogqirha badla ngokukucela ukuba wenze uvavanyo lwe-"brain imaging" (umz. i-"MRI scans"). Ukwenza yonke into ngokuchanekileyo kubaluleke kakhulu ekuchacheni kwakho ngokukhawuleza.

Ithini ingqikelelo yesi sifo?

Lo mbuzo ngowona mthwalo mkhulu kwiingqondo zabantu abaninzi. Imbono ye-choroid plexus carcinoma, oko kukuthi, amathuba okuchacha kunye nobude bobomi, yahluka kakhulu kumntu nomntu. Kukho izinto ezibalulekileyo ezichaphazela le meko:

• Ubudala besigulana (iziphumo zingahluka kubantwana abancinci).
• Imeko yempilo yesigulana iyonke.
• Nokuba lonke ithumba lisusiwe ngexesha lotyando, okanye inxalenye yalo kuphela. (Ukuba ithumba linokususwa ngokupheleleyo, imeko ilungile.)

Kwakhona, ezi zinto zichaphazela indlela izinto ezibonakala ngayo:

• Ukuba ithumba libuya emva kotyando okanye olunye unyango (`ukuphinda libuye`).
• Ukuba umhlaza usasazeka (usasazeka) ukusuka kwindawo yawo yokuqala ukuya kwezinye iindawo zomzimba, umzekelo, umqolo.

Asingomntu wonke ofanayo, ngoko ke kungcono kwaye kuchanekileyo ukubuza iqela lakho lezonyango ukuba ulindele ntoni ngokwemeko yakho.

Ngokwezibalo, izinga lokusinda iminyaka emihlanu iyonke kwi-choroid plexus carcinoma liphakathi kwama-40% nama-60%. Oku kuthetha ukuba kubantu abali-10 abafunyaniswe benesifo, aba-4 ukuya kwaba-6 baya kuphila iminyaka emihlanu nangaphezulu. Nangona kunjalo, kumntu onesifo semfuza esikhankanyiweyo ngaphambili i-Li-Fraumeni syndrome, eli nani kuthiwa liphantsi njenge-30 %.

Musa ukothuka zezi zibalo. Ezi zizinto nje eziqhelekileyo. Imeko yomntu wonke, indlela asabela ngayo kunyango, kunye nemfazwe yahlukile. Ngokuhambela phambili kwesayensi yezonyango, ezi meko ziya zisiba ngcono imihla ngemihla.

Sifanele siye nini kugqirha ngokuqinisekileyo?

Ukuba wena okanye umntwana wakho uyaqhubeka nokuba nenye okanye ngaphezulu kwezi mpawu zikhankanyiweyo apha ngasentla, ingakumbi ukuba ubona nayiphi na kwezi zilandelayo, ngokuqinisekileyo kuya kufuneka ubone ugqirha ofanelekileyo ngaphandle kokuchitha ixesha :

• Utshintsho olucacileyo kwindlela yokuziphatha. Umzekelo, ukudideka ngesiquphe, ukucaphuka kakhulu, ukuvuseleleka.
• Ubunzima bokuphefumla.
• Ubunzima bokuhamba, ukulahlekelwa yibhalansi.
• Ukuxhuzula ngequbuliso (`Ukuxhuzula`).
• Intloko ebuhlungu kakhulu, enganyamezelekiyo.
• Utshintsho olukhawulezileyo embonweni okanye kwintetho.

Yeyiphi imibuzo ebalulekileyo ekufuneka uyibuze ugqirha?

Xa ubona ugqirha wakho, ungabuza imibuzo efana nale ukuze uqonde kakuhle imeko yakho. Ungoyiki ukubuza yonke into esengqondweni yakho:

• "Gqirha, loluphi kanye uhlobo lwethumba lobuchopho endinalo/umntwana wam?"
• "Zeziphi iindlela zonyango ezilungileyo zoku? Zeziphi ezilungele mna/umntwana wam?"
• "Zithini iziphumo ebezingalindelekanga emva konyango?"
• "Kuza kufuneka kangaphi mna/umntwana wam ukuba ndenze uvavanyo olufana ne-"imaging` scans"?"
• "Injani imeko yam/yomntwana wam ngale meko?"

Ilizwi eliya kusapho, ingakumbi kubazali...

Xa umntwana wakho efunyaniswa ukuba une-choroid plexus carcinoma, kuyinto eqhelekileyo ukuziva ngathi lonke ihlabathi lakho liwile. Yonke into iqala ukwenzeka ngokukhawuleza. Uza kudibana neqela elikhulu loogqirha, kuquka oogqirha bezifo zengqondo abatsha kunye noogqirha bezifo zomhlaza. Ikhalenda yakho iza kuzaliswa luvavanyo, amadinga kagqirha, kunye notyando. Emva kovuyo lokuqala, kuya kufuneka ulinde ixesha elide ukuba iziphumo zibuye, ukuze ufumane amanyathelo alandelayo. Eli xesha lokulinda linokuba nzima kakhulu kwaye libe nzima.

Kodwa, yonke imzuzu encinci onokuyichitha nomntwana wakho ngelo xesha ixabisekile. Funda i-lullaby entsha yokumthoba ukuze alale, bukela iikhathuni okanye iimuvi azithandayo kunye, zama ukufumana into entsha eninokuyenza kunye enizisela uvuyo.

Kunzima ukuphila kwixesha langoku, uxhalabele i-scan elandelayo, ingxelo yovavanyo olulandelayo. Kodwa nokuba loo scan okanye ingxelo ityhila ntoni na, unokuhlala ubeke ecaleni amaxhala akho kunye noloyiko lwakho kwaye wonwabe ngexesha elixabisekileyo olichithe nomntwana wakho. Awuwedwa. Baninzi abantu abanokukunceda kwaye bakuphulaphule.

Okokugqibela, ezona zinto zibalulekileyo ekufuneka uzikhumbule (Umyalezo Wokuya Ekhaya)

Kulungile, masishwankathele ezona zinto zibalulekileyo ekufuneka uzikhumbule ngale ``Choroid Plexus Carcinoma'' exoxwe ngayo ixesha elide?

• I-Choroid Plexus I-Carcinoma luhlobo lomhlaza olungaqhelekanga kodwa olukhula ngokukhawuleza olukhula kwizicubu zobuchopho ezibizwa ngokuba yi-choroid plexus. Ichaphazela ngakumbi abantwana abancinci kunye neentsana .
• Ukuba unempawu enye okanye ezingaphezulu ezifana nokulala kakhulu, iintloko ezibuhlungu ezingapheliyo, ukuhlanza rhoqo, ukuxhuzula, okanye iingxaki zokubona ngenxa yezizathu ezingaziwayo, musa ukuchitha ixesha kwaye funa ingcebiso kagqirha ngoko nangoko .
• Unyango oluphambili olusetyenziswayo lutyando, i-chemotherapy, kunye nonyango lwe-radiation . Ngamanye amaxesha kunokusetyenziswa unyango olungaphezu kolunye.
• Nangona olu luhambo olunzima nolunzima, ukuba wena okanye umntu kusapho lwakho ujongene nale meko, khumbula ukuba awuwedwa . Phila ngale meko ngenkxaso yeqela lakho lezonyango, usapho kunye nabahlobo. Ukuhlala unethemba kwaye uqinile kubaluleke kakhulu kule mfazwe.

Siyathemba ukuba olu lwazi luluncedo kuwe. Impilo entle kuni nonke!

I- Choroid Plexus Carcinoma, umhlaza wobuchopho, umhlaza wobuntwana, ulwelo lomgogodla, iimpawu zomhlaza, unyango lomhlaza, ithumba lobuchopho, umhlaza wobuntwana