Ingcaciso elula yamaqhuqhuva angaqhelekanga emilenzeni nasezingalweni: Masifunde ngeClear Cell Sarcoma.

Ngaba wakha waba neqhuma okanye ukukhula okungaqhelekanga phantsi kwesikhumba somlenze okanye ingalo yakho okungayi kuphela? Kusenokungabi buhlungu xa ulicinezela. Kodwa ukuba livakala ngathi liyakhula, lisenokuba yinto ekufuneka ixhalatyelwe. Namhlanje siza kuthetha ngomhlaza ongaqhelekanga onokubangela iimpawu ezifanayo, kodwa kufanelekile ukuba uqaphele. Libizwa ngokuba yiClear Cell Sarcoma .

Yintoni iClear Cell Sarcoma?

Ngamafutshane, i-clear cell sarcoma luhlobo lomhlaza olungaqhelekanga kakhulu oluvela kwizicubu ezithambileyo . Luwela kudidi olubizwa ngokuba yi-sarcoma . Ngokuqhelekileyo, ezi ntlobo zomhlaza ziqala kwimisipha , kwizicubu ezidibanisa izihlunu namathambo, nakwizicubu ezithambileyo ezijikeleze izihlunu, emilenzeni yakho, ingakumbi ezinyaweni zakho.

Njengezinye iintlobo zomhlaza, i-clear cell sarcoma kulula kakhulu ukuyinyanga ukuba ifunyenwe ngaphambi kokuba isasazeke kwamanye amalungu omzimba. Oogqirha banyanga le meko ngotyando , kwaye ukuba kuyimfuneko , unyango lwemitha kwaye ngamanye amaxesha i-chemotherapy . Ngelishwa, nasemva konyango, esi sifo sinethuba elikhulu lokuphinda sibuye. Yiyo loo nto abaphandi bezonyango besoloko bekhangela iindlela ezintsha zokunyanga i-clear cell sarcoma.

I-clear cell sarcoma ichaphazela njani umzimba wam?

I-Clear cell sarcoma idla ngokuqala kwizicubu ezithambileyo ezijikeleze imisipha kunye neethambo zakho, okanye kumaleko wezicubu ezibizwa ngokuba yi-fascia . I-Fascia ifana nebhande elijikeleza yonke into emzimbeni wethu.

Ekuqaleni, usenokungaqapheli nto. Kodwa uza kuyibona xa umhlaza ukhula uze ube yiqhuma elinokuvakala phantsi kwesikhumba somlenze okanye unyawo lwakho. Eli qhuma linokubonakala njengeqhuma elivela xa ubetha umlenze okanye unyawo lwakho ngamandla, kodwa umahluko obalulekileyo kukuba eli qhuma alinciphi ngokuhamba kwexesha . I-Clear cell sarcoma ikhula kancinci kakhulu. Nangona kunjalo, xa isasazeka kwizicubu zakho ezithambileyo eziphantsi kolusu, isenokuba sele iqalile ukusasazeka kwezinye iindawo zomzimba wakho.

Khawucinge nje, ufumana iqhuma elincinci emlenzeni wakho uze ungalinaki, ucinge, "Owu, oku kumele ukuba kusandul' ukwenzeka." Emva kweeveki okanye iinyanga, kusekho, mhlawumbi kukhulu kancinci. Kwimeko enjalo, ngokuqinisekileyo kungcono ukufuna ingcebiso kagqirha.

Isasazeka phi i-clear cell sarcoma?

I-Clear cell sarcoma inokusasazeka kwezinye iindawo zomzimba, ikakhulu:

• Inkqubo yakho yokwetyisa (indlela yokugaya ukutya)
• EyakhoUkuya emiphungeni
• Inkqubo yakho ye-lymphatic , eyile lymph nodes kunye nemithambo ye-lymph emzimbeni wakho.

Ingaba le yimeko eqhelekileyo?

Hayi, akunjalo konke konke. Olu luhlobo olungaqhelekanga kakhulu lomhlaza. Enyanisweni, i-sarcoma ikwaluhlobo olungaqhelekanga lomhlaza. Umzekelo, eMelika, malunga nabantu abayi-1,600 bafunyanwa bene-sarcoma minyaka le. Linani elincinci elo, malunga ne-1% yazo zonke iintlobo zomhlaza kubantu abadala. I-clear cell sarcoma, yi-1% kuphela yazo zonke iintlobo zomhlaza. Ngoko unokucinga ukuba oku kunqabile kangakanani.

Ngubani onokuba nethuba elikhulu lokufumana i-clear cell sarcoma?

Nangona i-clear cell sarcoma inokukhula nakweyiphi na iminyaka, idla ngokubonakala kubantu abancinci abaphakathi kweminyaka eli-15 nengama-40 , ingakumbi abo baneminyaka engama-20 nengama-30.

Zithini iimpawu ze-clear cell sarcoma?

Njengoko besikhe sathetha ngako ngaphambili, uphawu oluqhelekileyo sisiqhuma esingasuki phantsi kwesikhumba emlenzeni okanye elunyaweni . Esi siqhuma sisenokuba buhlungu okanye singabi buhlungu. Kodwa ukuba sikhona kwaye sivakala ngathi siyakhula, olo luphawu olukhulu.

Ukongeza, ezi mpawu zilandelayo zinokuvela kamva:

• Ukudinwa kakhulu ngaphandle kwesizathu
• Ukunciphisa umzimba ngendlela engachazekiyo
• Ukubila ebusuku

Yintoni ebangela i-clear cell sarcoma?

Oku kuyinkimbinkimbi kancinci. Abaphandi bezonyango bafumanise ukuba i-clear cell sarcoma ibangelwa ziinxalenye zee -chromosomes ezimbini kwiiseli zethu zomzimba ezitshintshana iindawo, nto leyo edala i -fused gene entsha.

Kalula nje, nantsi into eyenzekayo:

Xa iiseli zomzimba wethu zahlukana, ngamanye amaxesha ii-chromosome ezimbini ziyaqhekeka kwaye iziqwenga eziqhekekileyo ziyatshintshana. Kule meko, iziqwenga ze-chromosome ezitshintshiweyo ziqulathe ii-genes ezibizwa ngokuba yi -EWSR1 kunye ne-ATF1 . Iproteni eveliswa yi-gene ye-EWSR1 ibonakala ibalulekile ekusebenzeni kweseli. I-gene ye-ATF1 inceda ukulawula ukukhula kweseli. Xa ezi chromosomes zibuya kunye, iziqwenga ze-gene ezitshintshiweyo ziphelela kwiindawo ezingafanelekanga. Oogqirha bakubiza oku ngokuthi yi-reciprocal translocation . Isizathu esichanekileyo sokuba oku kwenzeke asikaziwa.

Nje ukuba zidluliselwe kwi-chromosome entsha, ii-genes ezitshintshiweyo ziyadibana ukuze zenze i-gene edibeneyo ebizwa ngokuba yi-EWSR1/ATF1 . Abaphandi bakholelwa ukuba le gene edibeneyo yeyona nto ibangela i-clear cell sarcoma.

Oogqirha bayixilonga njani i-clear cell sarcoma?

Xa usiya kugqirha oneqhuma elinjalo, uza kuqala akuhlole aze ajonge indawo eliqhuma kuyo, ubungakanani balo, nezinye izinto. Emva koko ungadinga i-MRI scan (Magnetic Resonance Imaging - MRI).Kunokwenzeka.

Nangona kunjalo, ukuxilongwa kwe-clear cell sarcoma kuqinisekiswa yi-biopsy, equka ukuthatha iqhekeza elincinci lesicubu kwiqhubu . Xa le sampulu yesicubu ihlolwa phantsi kwe-microscope, iingcali ze-pathologists, iingcali ezihlola isicubu kwilebhu, zikhangela ubukho be-EWSR1/ATF1 fused gene esithethe ngayo ngaphambili.

Inyangwa njani i-clear cell sarcoma?

Injongo ephambili yoogqirha kukuthintela i-clear cell sarcoma ukuba ingasasazeki kwezinye iindawo zomzimba. Kwiimeko ezininzi, inyathelo lokuqala kukwenza utyando lokususa ngokupheleleyo ithumba . Ukuba umhlaza usasazeke kwi-lymph nodes, ezo lymph nodes nazo ziyasuswa. Oku kulandelwa lunyango oluncedisayo . Oku kudla ngokubandakanya unyango lwe-radiation ukubulala naziphi na iiseli zomhlaza eziseleyo.

Abaphandi bezonyango okwangoku baphanda ezinye iindlela zonyango. Umzekelo, bajonga ukuba i-immunotherapy isebenza kangakanani ekulawuleni i-clear cell sarcoma. Bakwavavanya nokuba amayeza asetyenziswa ngoku ukunyanga ezinye iintlobo zomhlaza anokunceda na ekuthinteleni ukusasazeka kwe-clear cell sarcoma.

Into ebalulekileyo kukuba i-clear cell sarcoma yimeko enokuthi ibuye kwakhona. Ukuba oko kuyenzeka, kunokufuneka wenze utyando olongezelelekileyo kunye nonyango olungaphezulu lwemitha. Kwaye ngenxa yokuba inokusasazeka ngokukhawuleza, oogqirha baya kukujonga rhoqo ukuze babone ukuba ingaba kukho iithumba ezintsha ezikhulayo na.

Ndingawunciphisa na umngcipheko wam wokuba ne-clear cell sarcoma?

Ngelishwa, akukho nto unokuyenza ukunciphisa umngcipheko wakho wokuba nale meko. Kuba abaphandi bezonyango abakafumani naziphi na izinto ezithile ezinokubangela ukuba kubekho i-clear cell sarcoma. I-risk factor ngumsebenzi okanye imeko eyonyusa amathuba okuba nesifo.

Ngaba i-clear cell sarcoma inganyangeka ngokupheleleyo?

Oogqirha banokunyanga i-clear cell sarcoma, oko kuthetha ukuba banokususa ithumba baze bazame ukulawula ukusasazeka kwalo. Nangona kunjalo, asiyonto inganyangekiyo ngokupheleleyo . Rhoqo, i-clear cell sarcoma inokusasazeka kwezinye iindawo zomzimba ngexesha lokufunyaniswa kwayo. Oku kwenza kube nzima ukuyinyanga. Kwakhona kunokwenzeka ukuba ibuye emva konyango.

Ingakanani ixesha lokuphila komntu one-clear cell sarcoma?

Ulindelo lobomi luqikelelo oluqikelelweyo lokuba uza kuphila ixesha elingakanani, ngokusekelwe kwimpilo yakho iyonke kunye nezinto zakho zobuqu. Uphononongo luka-2018 lwe-US National Cancer Database lubonise ukuba phakathi kwabantu abane-clear cell sarcoma,Ikwathi ama-50% asaphila emva kweminyaka emihlanu emva kokufunyaniswa ukuba anaso esi sifo, kwaye ama-38% asaphila emva kweminyaka elishumi emva kokufunyaniswa ukuba anaso .

Nokuba sithetha ngobude bobomi okanye amazinga okusinda, kubalulekile ukukhumbula ukuba la ngamanani nje oqikelelo, hayi uqikelelo. Ubude bobomi luqikelelo olusekelwe kuluntu lonke. Amanani okusinda komhlaza ngamanani oqikelelo asekelwe ekubeni abantu baphila ixesha elingakanani emva kokufumana unyango lohlobo oluthile lomhlaza. Zininzi izinto ezinokuchaphazela ubude bobomi bomntu okanye amathuba abo okusinda kumhlaza. Ukuba une-clear cell sarcoma, ugqirha wakho unokukunika ulwazi olungcono malunga nokuba ulindele ntoni.

Ngaba i-clear cell sarcoma ingabulala?

Ewe, inokubulala. Ngokubanzi, abantu abane-clear cell sarcoma esasazeke kwezinye iindawo zomzimba banamathuba amaninzi okufa kwangethuba kunabo bafumana unyango ngaphambi kokuba umhlaza usasazeke.

Ndifanele ndimbone nini ugqirha wam?

Ngenxa yokuba i-clear cell sarcoma inokuphinda ivele emva konyango, ugqirha wakho unokufuna ukukubona rhoqo emva kweenyanga ezintathu kwiminyaka emibini yokuqala emva kokugqiba unyango, kuxhomekeke kwimeko yakho. Kubalulekile ukuba uhlolwe rhoqo emva koko.

Ndingayibuza yiphi imibuzo ugqirha wam?

I-Clear cell sarcoma sisifo esingaqhelekanga kakhulu. Sinokuba yingozi ebomini. Ukuba ufunyaniswe unale meko, ungabuza ugqirha wakho le mibuzo:

• Iphi ithumba? Ingakanani ithumba?
• Ingaba ithumba lisasazeke nakweyiphi na indawo emzimbeni wam?
• Loluphi unyango olucebisayo?
• Zithini iziphumo ebezingalindelekanga zonyango?
• Ukuba ndityandwa, angakanani amathuba okuba ithumba libuye?
• Ngaba kukho naziphi na iimvavanyo zeklinikhi endinokuziqwalasela?

Isishwankathelo kunye nomyalezo oya nawo ekhaya

I-Clear Cell Sarcoma sisifo esinzima kakhulu. Sinqabile kakhulu. Sichaphazela abantu abambalwa ngonyaka. Kwaye sikhula kancinci kakhulu. I-sarcoma inokusasazeka ize ibulale xa uninzi lwabantu lubona utshintsho emizimbeni yabo.

Kodwa khumbula, oogqirha banokuyinyanga i-clear cell sarcoma. Bangayisusa ithumba ngotyando, kwaye banokukunika unyango lokubulala naziphi na iiseli zomhlaza eziseleyo. Ngelishwa, i-clear cell sarcoma inokubuya rhoqo. Ngoko ke kubalulekile ukuba uhlolwe rhoqo kwaye uqaphele naluphi na utshintsho emzimbeni wakho.

Abaphandi bezonyango bafuna iindlela ezintsha zokunyanga i-clear cell sarcoma. Ukuba une-clear cell sarcoma, kukho iimvavanyo ezintsha zeklinikhi ezikhoyo.Ukuba unomdla wokufunda okungakumbi ngayo, buza ugqirha wakho ngayo kwaye ufumane iingcebiso. Ungaze ulahle ithemba. Ngeengcebiso zonyango ezifanelekileyo kunye nenkxaso, ungajongana nale ngxaki.

i- clear cell sarcoma, umhlaza wezicubu ezithambileyo, iithumba zomlenze, iithumba zomlenze, i-sarcoma, iimpawu zomhlaza, unyango lomhlaza