Ngaba une-high blood pressure, okanye i-hypertension? Usenokuba uthatha amayeza amabini okanye amathathu owanikwe ngugqirha wakho. Kodwa ngaba kusenzima ukulawula uxinzelelo lwakho lwegazi? Ngaba uziva udiniwe, ubuthathaka, kwaye udla ngokuphelelwa ngamanzi emzimbeni? Ukuba kunjalo, unobangela wemeko yakho usenokuba yinto engeyiyo i-blood pressure eqhelekileyo. Namhlanje siza kuthetha ngemeko enjalo. Yi-Primary Aldosteronism, okanye i-Conn's Syndrome.
Ngamafutshane, yintoni i-Primary Aldosteronism?
Le yinto efuna ingcaciso encinci. Emizimbeni yethu, kukho amadlala amabini amancinci ngaphezu kwezintso. La madlala siwabiza ngokuba ngamadlala e-adrenal, okanye ngesiNgesi, amadlala e-adrenal . La madlala avelisa iintlobo ezahlukeneyo zeehomoni ezibalulekileyo emzimbeni wethu.
I-Aldosterone yi-hormone ye-steroid eveliswa zezi glands. Umsebenzi ophambili wale hormone kukulawula amanqanaba esodium (ityuwa) kunye ne-potassium egazini lethu. Ngale ndlela, le hormone ikwanceda ekulawuleni ulungelelwaniso lwamanzi emzimbeni wethu kunye noxinzelelo lwegazi.
Ngoko ke, i-Primary Aldosteronism iyenzeka xa amadlala akho e-adrenal evelisa i-hormone aldosterone eninzi kakhulu ngesizathu esithile. Xa amanqanaba e-aldosterone enyuka, ubungakanani be-sodium (ityuwa) emzimbeni wakho buyanda kwaye ubungakanani be-potassium buyancipha. Oku kuphumela kuxinzelelo lwegazi oluphezulu olungalawulekiyo kunye namanqanaba e-potassium aphantsi egazini (i-hypokalemia).
Esi ngaphambili sasithathwa njengesifo esingaqhelekanga, kodwa ngoku kufunyaniswe ukuba phakathi kwe-5% kunye ne-10% yabantu abadala abanoxinzelelo lwegazi oluphezulu banokuba nale meko.
Ziziphi iimpawu eziphambili zesi sifo?
Ayingabo bonke abantu abanale meko abaya kuba neempawu ezifanayo. Kodwa ezi zezona mpawu zixhaphakileyo. Masizijonge kwitheyibhile.
| Uphawu | Ingcaciso elula |
|---|---|
| Uxinzelelo lwegazi oluphezulu (uxinzelelo lwegazi oluphezulu) | Olu luphawu oluphambili, ingakumbi uxinzelelo lwegazi oluphezulu olunzima ukululawula nokuba usebenzisa amayeza amaninzi. |
| I-potassium ephantsi egazini (i-Hypokalemia) | Uvavanyo lwegazi lunokubonisa amanqanaba aphantsi e-potassium. Oku kunokubangela ukuxhuzula kwemisipha kunye nokuba ndindisholo. |
| Ukudinwa rhoqo | Ukuziva udiniwe kwaye ungenabomi ngalo lonke ixesha ngaphandle kwesizathu. |
| Intloko ebuhlungu | Intloko ebuhlungu rhoqo. |
| Ukoma kakhulu kunye nokuchama rhoqo | Ukuziva unxaniwe ngaphezu kwesiqhelo kwaye ngenxa yoko kufuneka uchame rhoqo. |
| Ubuthathaka bemisipha kunye nokuqaqamba kwemisipha | Ukuziva ngathi izihlunu emilenzeni nasezingalweni ziyaqengqeleka, ingakumbi ngenxa yokuba i-potassium incinci. |
| Umbono ofipheleyo | Ngamanye amaxesha umbono ubonakala ungacacanga kancinci. |
Kutheni i-hormone ye-aldosterone isanda ngolu hlobo?
Kusenokuba nezizathu ezahlukeneyo zoku.
- Iithumba ezingengomhlaza kwi-adrenal glands: Le yimbangela yesi sifo kubantu abaninzi. Ithumba elincinci, elingengomhlaza (i-adenoma) likhula kwi-adrenal glands enye okanye zombini, nto leyo evelisa i-hormone aldosterone eninzi kakhulu.
- I-Bilateral adrenal hyperplasia: Ngamanye amaxesha, ngaphandle kwethumba, iiseli kuzo zombini ii-adrenal glands zinokuba zisebenza kakhulu kwaye zivelise iihomoni ezininzi kakhulu.
- Izizathu zofuzo: Le meko inokuthi ifuzwe kwezinye iintsapho. Umzekelo ngu `(Congenital Adrenal Hyperplasia)`.
- Umhlaza we-adrenal: Le yimbangela engaqhelekanga kakhulu.
Umahluko phakathi kwe-Aldosteronism ePhambili neyeSibini
Kukho enye into ebalulekileyo ekufuneka uyazi. I-Primary Aldosteronism, esithethe ngayo, yingxaki eyenzeka kwi-adrenal gland ngokwayo, ebangela ukwanda kwehomoni.
Kodwa ngamanye amaxesha, amanqanaba e-aldosterone anokunyuka ngenxa yezinye iimeko zempilo emzimbeni. Umzekelo, le hormone inokunyuka nakwiimeko ezifana nokusilela kwentliziyo, isifo sesibindi, okanye i-renal artery stenosis. Oku sikubiza ngokuba yi -Secondary Aldosteronism . Ugqirha uya kwahlula ngokuchanekileyo phakathi kwezi meko zimbini.
Ungayiqonda njani le nto?
Ukuba uneempawu ezichazwe apha ngasentla, ugqirha wakho uza kuqala ajonge uxinzelelo lwakho lwegazi. Emva koko, ukuba kukho amathandabuzo malunga nale meko, uza kukuthumela kwiimvavanyo zegazi ezikhethekileyo.
- Amanqanaba ehomoni egazini: Oku kulinganisa ikakhulu amanqanaba ehomoni i-aldosterone kunye ne-renin. Kwi-aldosteronism yokuqala, amanqanaba e-aldosterone aphezulu kwaye amanqanaba e-renin aphantsi.
- Uvavanyo lweNqanaba le-Electrolyte: Olu vavanyo luvavanya amanqanaba e-sodium kunye ne-potassium egazini lakho.
Kubalulekile: Ukuba sele usebenzisa amayeza oxinzelelo lwegazi, amanye ala mayeza anokuchaphazela iziphumo zolu vavanyo lwegazi. Ke ngoko, ukuze ufumane uxilongo oluchanekileyo, ugqirha wakho unokukucebisa ukuba utshintshe okanye uyeke amayeza akho okwethutyana.
Ukuba uvavanyo lwegazi luyayiqinisekisa le meko, inyathelo elilandelayo kukuhlola amadlala e-adrenal ukuze kufunyanwe unobangela. Oku kudla ngokwenziwa nge-CT scan (Computed Tomography) okanye i-MRI scan (Magnetic Resonance Imaging) .
Zithini iindlela zonyango zoku?
Unyango lwesi sifo luxhomekeke kwisizathu. Kukho iindlela ezimbini eziphambili zonyango.
1. Unyango ngamayeza
Ukuba zombini ii-adrenal glands zisebenza kakhulu (hyperplasia), utyando alusoloko lwenziwa. Endaweni yoko, kunikwa amayeza athintela ukusebenza kwehomoni i-aldosterone. Amayeza asetyenziswa kakhulu yi -spironolactone kunye ne -eplerenone . La mayeza anokulawula uxinzelelo lwegazi kwaye abuyisele amanqanaba e-potassium.
2. Unyango ngotyando
Ukuba i-CT okanye i-MRI scan iqinisekisa ukuba kukho ithumba (i-adenoma) kwi-adrenal gland enye kuphela, unyango olungcono kukususa elo gland ngotyando. Olu tyando lubizwa ngokuba yi-adrenalectomy . Oku kudla ngokwenziwa njengotyando lwe-keyhole (utyando lwe-laparoscopic) ukuze ukuchacha kube ngokukhawuleza.
Emva kotyando, uxinzelelo lwegazi lwabantu abaninzi lubuyela kwisimo esiqhelekileyo okanye lunokulawulwa ngamayeza amancinci kakhulu.
Kuza kwenzeka ntoni ukuba ayinyangwa?
Ukuba le meko ayinyangwa, iingxaki ezinkulu zinokwenzeka ngenxa yoxinzelelo lwegazi oluphezulu oluhlala ixesha elide kunye nokungalingani kwe-electrolyte.
- Ukuhlaselwa yintliziyo okanye ukungaphumeleli kwentliziyo
- Istroke
- Ukungasebenzi kakuhle kwezintso
- Ukubetha kwentliziyo okungaqhelekanga (i-Arrhythmia)
- Ukukhubazeka okwethutyana
Ngoko ke, ukuba uneempawu, kubaluleke kakhulu ukubona ugqirha ngokukhawuleza uze ufumane unyango.
Umyalezo Wokuya Ekhaya
- I-aldosteronism ephambili yimeko ebangelwa kukuveliswa kakhulu kwehomoni i-aldosterone yi-adrenal glands.
- Iimpawu eziphambili luxinzelelo lwegazi oluphezulu kunye ne-potassium ephantsi egazini, nto leyo ekunzima ukuyilawula nokuba kusetyenziswe amayeza aliqela.
- Iimpawu ezinje ngokudinwa rhoqo, iintloko ezibuhlungu, ukoma kakhulu, kunye nokuxhuzula kwemisipha nazo zinokubakho.
- Uvavanyo lwegazi kunye neeskeni zinokusichonga ngokuchanekileyo esi sifo kunye nesizathu saso.
- Ngokuxhomekeke kwisizathu, le meko inokulawulwa ngempumelelo ngamayeza okanye ngotyando.
- Ukuba unale mpawu, ingakumbi ukuba unengxaki yokulawula uxinzelelo lwakho lwegazi, qiniseka ukuba uthetha nogqirha wakho ngayo.
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