Xa uxelelwa ukuba une-cholesterol ephezulu, ugqirha wakho mhlawumbi uza kukuqalisa ukusebenzisa iyeza le-statin. Lelo lolona nyango luqhelekileyo esilwaziyo. Kodwa isayensi yezonyango iyaphucuka imihla ngemihla. Namhlanje ndiza kukuxelela ngezinye zonyango zamva nje neziphucukileyo eziye zafika kwaye ziza kulawula i-cholesterol. Ezi zifana nekamva lezonyango.
Izinto ezintathu ekufuneka sizazi malunga ne-cholesterol kuqala
Ngaphambi kokuba sithethe ngamayeza amatsha, kubaluleke kakhulu ukukhumbula ezi zinto zintathu malunga ne-cholesterol.
1. I-cholesterol yeyona nto ibangela isifo sentliziyo: Iiseli zomzimba wethu zifuna i-cholesterol ethile. Kodwa ukuba ininzi kakhulu, inokuba yingozi kakhulu. Le cholesterol igqithisileyo inokuqokelelana kwimithambo yegazi yethu (i-plaque), enokuyivala. Le yeyona nto ibangela ukuhlaselwa yintliziyo.
2. Kukho unyango loku: Nokuba i-cholesterol ibekwe ngaphakathi kwemithambo yegazi yakho, kukho amayeza asebenzayo namhlanje anokuyinciphisa kwaye ayilawule.
3. Olu nyango lukhuselekile: La mayeza akhuselekile kwaye asebenza kakuhle kakhulu. Ngamanye amaxesha kunokubakho iziphumo ebezingalindelekanga ezincinci, kodwa zinokulawulwa ngokuthetha nogqirha wakho. Ngoko ke ungakhathazeki.
Amayeza amatsha adlula ngaphaya kwee-statins
Iistatins zezona ziphambili kunyango lwe-cholesterol, kodwa ngoku kukho amayeza aphucukileyo afumanekayo. Makhe sijonge ezimbalwa zazo.
| Uhlobo lweyeza | Ukusebenza okulula kunye namanqaku abalulekileyo |
|---|---|
| I-Ezetimibe (Zetia) | Eli liyeza elinikwa kunye nee-statins. Ngoku lixabiso eliphantsi. Liluncedo ngakumbi kubantu abaneminyaka engaphezu kwama-75 ubudala. Eli lisisombululo esilungileyo kwabo banengxaki yokulawula amanqanaba abo e-cholesterol ngee-statins zodwa. |
| Izithinteli ze-PCSK9 | Olu lutshintsho olukhulu. Olu luhlobo lwee-antibodies ze-monoclonal ezinikwa njengesitofu sokugonya. Ngamafutshane, i-cholesterol 'embi' emizimbeni yethu, oko kukuthiI-low-density lipoprotein (LDL) kufuneka iye esibindini ukuze icocwe. Kodwa iproteni ebizwa ngokuba yi-PCSK9 iphazamisana nokucocwa kwale LDL. Eli yeza lithintela loo protein ye-PCSK9. Emva koko isibindi sinokucoca nokususa i-LDL cholesterol ngokukhawuleza. |
| Inclisiran (Leqvio) | Oku kufana 'nogonyo' lwe-cholesterol. Lugonyo olunikwa rhoqo emva kweenyanga ezi-6. Luchaphazela imolekyuli ebizwa ngokuba yi-RNA , ephethe ulwazi kwiijini zethu, kwaye inciphisa ukuveliswa kweproteni ye-PCSK9 ekhankanyiweyo ngaphambili. Oko kuthetha ukuba lunyango olujoliswe kakhulu. |
| I-Bempedoic Acid | Oku kufana nee-statins, kodwa kuchaphazela inxalenye eyahlukileyo yenkqubo yokuveliswa kwe-cholesterol. Ayibangeli iintlungu zemisipha (i-myalgia) ezenzeka ngee-statins. Nangona kunjalo, inokunyusa amanqanaba e-uric acid kwaye inyuse kubantu abane-gout. Kukwakho nentetho yomngcipheko wokuqhekeka kwemisipha. Ke ngoko, kubalulekile ukuthetha nogqirha wakho rhoqo xa usebenzisa eli yeza. |
| I-Vascepa (iOyile yeNtlanzi eHlanjululweyo) | Le ayisiyo ipilisi yakho eqhelekileyo yeoyile yentlanzi evela kwikhemesti. Le yioyile yentlanzi ekhethekileyo enikwa ngugqirha. Iqulethe i-EPA ecocekileyo kuphela. Ukuba uthatha ii-statins kodwa amanqanaba akho e-triglyceride asephezulu, oku kunokukunceda ukunciphisa umngcipheko wakho wokuhlaselwa sisifo sentliziyo kunye nestroke. |
I-Cholesterol evela kwi-genes (Familial Hypercholesterolemia)
Kukho abantu abathile, nokuba batya kwaye bazilolonga kangakanani na, banamazinga aphezulu e-cholesterol. Isizathu soku yimeko evela kwiijini zabo, ebizwa ngokuba yi -familial hypercholesterolemia (FH) . Kwaba bantu, kunzima ukulawula i-cholesterol yabo ngonyango oluqhelekileyo.
"Kutheni ndisoloko ndimele ndibeke ityala kwi-cholesterol yam?" Yiloo nto izigulane zam ezine-FH ezihlala ziyibuza. Kufuneka siqonde ukuba oku akulona ityala lazo, yimeko yemfuza.
Khawuthelekelele indlela amachiza amatsha afana ne-'PCSK9 Inhibitors' axabiseke ngayo kubantu abanjalo. Ngenxa yala mayeza, okokuqala ngqa kwimbali, abantu abane-FH banokhetho lonyango oluphumelelayo.
Okungakumbi malunga 'nogonyo lwe-cholesterol'
Nangona abanye abantu besenokuyithanda ingcamango yokusebenzisa i-Inclisiran rhoqo emva kweenyanga ezi-6, abanye basenokuyoyika. "Ngaba ndiza kuhlala ndisebenzisa eli yeza iinyanga ezi-6? Kwaye ukuba ndineziphumo ebezingalindelekanga, ngaba ziya kuhlala iinyanga ezi-6?" Kungumbono olungileyo ukubuza imibuzo efana nale. Xoxa ngazo naziphi na iingxaki okanye uloyiko onalo nogqirha wakho malunga naliphi na iyeza olisebenzisayo. Lilungelo lakho.
Amayeza kuphela awanelanga! Indlela yokuphila yeyona nto ibalulekileyo
Nokuba sithetha kangakanani na ngezonyango eziphucukileyo, kukho into enye ongafanele uyilibale. Loo nto yindlela yokuphila enempilo.
- Ukutya: Kubalulekile ukutya ukutya okunciphisa i-cholesterol (ii-oats, irhasi, amantongomane, imifuno, iziqhamo), kwaye uphephe ukutya okucutshungulweyo, okufana neesoseji, iibhola zenyama, njl. Uphando lubonisa ukuba i-58% yokutya esikutyayo kucutshungulwe kakhulu.
- Ukuzilolonga: Ukuzilolonga imihla ngemihla akulungelanga nje kuphela ukulawula i-cholesterol, kodwa nakomzimba wonke.
- Ukutshaya notywala: Ukuziphepha ngokupheleleyo ezi zinto kubaluleke kakhulu kwimpilo yentliziyo.
Khawucinge nje, nokuba uthatha amayeza uze wehlise inani le-cholesterol yakho, ukuba uyaqhubeka nokutya ukutya okungenampilo kwaye ungazilolongi, umngcipheko wakho wokuba nesifo sentliziyo awuyi kuncipha kangako.
Ipilisi ayinakuze ithathe indawo yendlela yokuphila esempilweni. Ezi zimbini kufuneka zihambe kunye.
Ukuba sele unesifo sentliziyo, ukhe wahlaselwa yintliziyo, okanye wafakelwa i-stent, awunalo ixesha lokulinda. Kufuneka uqale ukuthatha amayeza akho ngoko nangoko, njengoko ugqirha wakho eyalele. Kufuneka wenze utshintsho kwindlela ophila ngayo.
Umyalezo Wokuya Ekhaya
- I-cholesterol yeyona nto ibangela isifo sentliziyo. Kodwa ungakhathazeki, kukho iindlela zonyango ezisebenzayo nezikhuselekileyo zokuyinyanga.
- Ukongeza kwii-statins, ngoku kukho unyango oluphambili nolujolise ngakumbi olufana nee-PCSK9 inhibitors kunye ne-Inclisiran.
- Ukuba unesifo se-cholesterol esibangelwa lufuzo (FH), eli yeza litsha linokuba luncedo kakhulu kuwe.
- Ukuba unemibuzo malunga namayeza owasebenzisayo, qiniseka ukuba uyayixoxa nogqirha wakho.
- Eyona nto ibalulekileyo: Nokuba iyeza lilungile kangakanani na, awunakuyilawula i-cholesterol yakho ngaphandle kwendlela yokuphila enempilo (ukutya okunempilo, ukuzilolonga). Amayeza aluncedo kuphela, isiseko kufuneka sibe yindlela yakho yokuphila.
💬 Comments (0)
Akukho zimvo zithunyelweyo okwangoku. Faka uluvo lwakho apha okokuqala.
Faka uluvo lwakho