Molo! Namhlanje siza kuthetha ngeyeza elinzima kancinci, kodwa elibaluleke kakhulu. Ukuba wena okanye umntu kusapho lwakho unesifo esibizwa ngokuba yiCystic Fibrosis, ugqirha wakho usenokuba unikile iyeza elibizwa ngokuba yiTrikafta. Liqulathe indibaniselwano yamayeza amathathu abizwa ngokuba yiElexacaftor, iTezacaftor, kunye neIvacaftor. Oku akufani neyeza eliqhelekileyo, kodwa liyeza elikhethekileyo eliya kwintsusa yesifo kwaye lisichaphazele. Ngoko makhe sibone ukuba eli yeza lisetyenziswa njani kanye kanye, zeziphi izinto ekufuneka uzilumkele, kunye neziphumo ebezingalindelekanga ezinokubangela.
Kwenzeka ntoni ngokwenene ngale mithi?
Ngamafutshane, i-Cystic Fibrosis sisifo semfuza esibangela ukuba ulwelo oluninzi lomzimba, ingakumbi i-mucus kwizitho ezifana nemiphunga kunye ne-pancreas, lube lukhuni kakhulu kwaye lunamathele. Oku kunokukhokelela kwiingxaki zokuphefumla, usulelo lwemiphunga, kunye neengxaki zokugaya ukutya.
Eli yeza, iTrikafta, lisebenza ngokulungisa iproteni engasebenzi kakuhle kwizigulana ezine-genetic mutation ethile ebizwa ngokuba yi- F508del . Oku kuthetha ukuba endaweni yokulawula iimpawu, inceda ekunciphiseni impembelelo yesiphene se-genetic esibangela esi sifo. Oku kuluncedo kakhulu kwezi zigulana.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale amayeza
Kubaluleke kakhulu ukuba ugqirha wakho ayazi imbali yakho epheleleyo yempilo ngaphambi kokuba anike eli yeza. Eli yeza alifanelekanga kuye wonke umntu. Qiniseka ukuba uxelela ugqirha wakho, ingakumbi ukuba unayo nayiphi na kwezi meko:
- Ukuba unesifo sezintso .
- Ukuba unesifo sesibindi (oku kubaluleke kakhulu).
- Ukuba une -allergies kwi-Elexacaftor, Tezacaftor, Ivacaftor, okanye naliphi na elinye iyeza, ukutya, okanye idayi equlethwe kweli yeza.
- Ukuba ukhulelwe okanye uceba ukuba nomntwana kungekudala.
- Ukuba ungumama oncancisayo.
Ngokusekelwe kolu lwazi, ugqirha wakho uya kugqiba ukuba eli yeza lifanelekile kuwe okanye ukuba kufuneka kutshintshwe idosi.
Ndingayisebenzisa njani kanye kanye le yeza?
Ukuze ufumane okuninzi kweli yeza, kubalulekile ukulisebenzisa njengoko kuyalelwe.
Eyona nto ibalulekileyo kukuhlala usela eli yeza kunye nokutya okuqulethe ioyile okanye amafutha , kuba amayeza akweli yeza afunxwa ngcono ngumzimba xa edibene namafutha.
Umzekelo, ungalithatha eli yeza:
- Ngamaqanda
- Nebhotolo yamandongomane
- Nesitya esinetshizi (umz. ipitsa yetshizi)
- Neavokhado
- Neyogathi (iyogathi enamafutha apheleleyo)
Ezinye izinto ekufuneka uzikhumbule:
- Ginya iipilisi ziphelele . Musa ukuziqhekeza okanye ukuzityumza, okanye uzihlafune njengetshungama.
- Zama ukusela amayeza akho ngexesha elifanayo yonke imihla. Wakuba ukwenze oku umkhwa, awuzukulibala.
- Ungaze uthathe eli yeza kunye neediliya okanye ijusi yegrapefruit. Izithako ezikwijusi yegrapefruit zinokuchaphazela kakhulu indlela eli yeza elisebenza ngayo.
- Musa ukuyeka ukuthatha amayeza akho de ugqirha wakho akuxelele ukuba wenjenjalo.
- Eli yeza ngamanye amaxesha linikwa abantwana abangaphezu kweminyaka emi-6 ubudala, kodwa kuphela phantsi kweliso elikhethekileyo lezonyango.
Kuthekani ukuba ngempazamo ndithathe amayeza amaninzi kakhulu?
Ukuba ucinga ukuba usele amayeza amaninzi kakhulu, ungoyiki. Tsalela umnxeba iZiko loLwazi lweeTyhefu zeSizwe kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko. Okanye uye kwiYunithi yoNyango oluNgxamisekileyo (i-ETU) yesibhedlele esikufutshane. Kungcono ukuba ungayiphatha le paki yamayeza xa uhamba.
Izinto ezingafanele zisetyenziswe kweli yeza
I-Trikafta liyeza elinamandla elinokusebenzisana namanye amayeza. Ngoko ke, kufuneka uxelele ugqirha wakho ngawo onke amayeza owasebenzisayo, kungekuphela nje lawo amiselwe ngugqirha wakho, kodwa namayeza athengiswa ngaphandle kwemvume kagqirha, iivithamini, kunye neemveliso zezityalo.
| Iziyobisi kunye nokutya okunokuchaphazela iTrikafta | |
|---|---|
| Kuphephe ukuthatha iTrikafta ngezi zinto | |
| Amanye amayeza okunyanga isifo sokuwa | I-Carbamazepine, iPhenobarbital, iPhenytoin |
| Ii-antibiotics | I-Rifampin, i-Rifabutin |
| Iimveliso zezityalo | I-St. John's Wort |
| Ukutya | Ijusi yegrapefruit kunye negrapefruit |
| Buza ugqirha wakho ukuba usebenzisa iTrikafta na. | |
| Amanye amayeza okubulala iintsholongwane | IClarithromycin, i-Erythromycin |
| Izinto ezilwa nokungunda | I-Fluconazole, i-Itraconazole, iKetoconazole |
| Amayeza okuthintela amajoni omzimba | I-Cyclosporine, iSirolimus, iTacrolimus |
| Okunye | I-Digoxin, iWarfarin, amayeza athile esifo seswekile (umz. iGlimepiride, iGlipizide) |
Zithini iziphumo ebezingalindelekanga ezinokubakho xa usebenzisa amayeza?
Njengalo naliphi na iyeza, iTrikafta inokubangela ezinye iziphumo ebezingalindelekanga. Ezinye zezi zinokuba yingozi. Ngoko ke kubaluleke kakhulu ukuqaphela oku.
| Imiphumela | Inkcazo kunye nento omawuyenze |
|---|---|
| Iziphumo ebezingalindelekanga ezinzulu ekufuneka zixelwe kugqirha wakho ngoko nangoko | |
| Iimpawu zomonakalo wesibindi | Umchamo otyheli okanye omdaka omnyama, ukutyheli kwamehlo okanye ulusu, iintlungu kwinxalenye ephezulu ngasekunene yesisu, ukungabi namdla wokutya, isicaphucaphu, ukudinwa okungaqhelekanga. Ukuba uqaphela oku, xelela ugqirha wakho ngoko nangoko. |
| Iimpendulo eziqatha ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe okanye ulwimi, ubunzima bokuphefumla. Le yimeko engxamisekileyo. |
| Utshintsho kwindlela yokubona | Xela ugqirha wakho naluphi na utshintsho, olufana nokufiphala kwamehlo amhlophe (ii-cataracts) okanye ukubona okufipheleyo. |
| Iswekile ephantsi egazini (iHypoglycemia) | Ukungazoli, ukudideka, isiyezi, indlala egqithisileyo, ukubila okugqithisileyo, ukungcangcazela, kunye nokubetha kwentliziyo ngokukhawuleza. |
| Iziphumo ebezingalindelekanga ezingaqhelekanga, kodwa kufuneka zixelwe kugqirha ukuba ziyaqhubeka | |
| Iingxaki zenkqubo yokugaya ukutya | Intlungu yesisu, urhudo, igesi. |
| Iimpawu eziqhelekileyo | Intloko ebuhlungu, isiyezi, umkhuhlane, ukuxinana kweempumlo. |
| Ingakumbi kubafazi | Intlungu ngexesha lokuya exesheni. |
Ukuba unezinye iimpawu ezingaqhelekanga ezingekho kolu luhlu, xelela ugqirha wakho ngazo.
Umyalezo Wokuya Ekhaya
- I-Trikafta liyeza elibaluleke kakhulu le-Cystic Fibrosis elichaphazela unobangela wesifo.
- Eli yeza lifanele lithathwe kunye nokutya okuqulethe ioyile okanye amafutha . Kuphephe ukulithatha ungenanto esiswini.
- Ungaze ulisebenzise eli yeza kunye nejusi yegrapefruit. Kwakhona, xelela ugqirha wakho ngazo zonke ezinye iziyobisi ozisebenzisayo.
- Funa uncedo lwezonyango ngokukhawuleza ukuba ubonakalisa iimpawu zokonakala kwesibindi (ukutyheli kwamehlo, umchamo omnyama) okanye ukuba une-allergy enzima.
- Dibana nogqirha ngomhla omiselweyo kwaye ungaphoswa luvavanyo lwegazi nolwamehlo alunikayo.
- Eli yeza lelakho wedwa. Ungaze wabelane ngalo nabanye.
💬 Comments (0)
Akukho zimvo zithunyelweyo okwangoku. Faka uluvo lwakho apha okokuqala.
Faka uluvo lwakho