Ngaba ufumana amaqhuma angaqhelekanga kwiindawo ezahlukeneyo emzimbeni wakho? Mhlawumbi unamazinyo amaninzi kunokuba kufuneka ube nawo xa ukhupha amazinyo? Nangona ezi zinto zinokubonakala ngathi zizinto eziqhelekileyo, ngamanye amaxesha kunokubakho ibali elibi emva kwazo. Namhlanje sithetha ngemeko yezonyango engaqhelekanga, kodwa ebaluleke kakhulu ekufuneka wonke umntu ayiqaphele. Yiyo leyo iGardner Syndrome.
Ngokulula nje, yintoni iGardner Syndrome?
Ngamafutshane, esi sisifo esingaqhelekanga esinokusifumana kubazali bethu ngokusebenzisa ii-genes. Sisifo esizuzwe njengelifa. Umntu onesi sifo uqala ukuba neethumba ezingaqhelekanga kwiindawo ezahlukeneyo zomzimba wakhe.
Okwenzekayo kukuba amakhulu eentsholongwane ezincinci zikhula ngaphakathi kwikholoni. Ezi ntsholongwane zibizwa ngokuba ziipolyps ngokwezonyango. Eyona nto iyingozi kukuba ukuba azinyangwa, zonke ezi polyps zinomngcipheko omkhulu wokuba ngumhlaza wekholoni .
Ukongeza kumathumbu amakhulu, izimila ezingezizo umhlaza zinokukhula emathanjeni, emathunjini, kulusu nakwezinye izicwili ezithambileyo. Abantu abanesi sifo nabo basengozini yokufumana ezinye iintlobo zomhlaza.
Ixhaphake kangakanani le meko? Ngubani oyifumanayo?
Esi sisifo esingaqhelekanga ngokwenene. Umzekelo, kwilizwe elifana neMelika, ngumntu omnye kuphela kwisigidi ofunyaniswa enaso esi sifo.
Ngenxa yokuba sisifo esidluliselwa kwilifa, abantu abaninzi abaneGardner syndrome banethuba elikhulu lokuba nomama okanye utata onesi sifo. Oku kuthetha ukuba sidluliselwa kwiijini ukusuka kwisizukulwana ukuya kwesinye.
Zithini iimpawu zoku?
Iimpawu zesifo sikaGardner ziyatshintsha ngokuhamba kwexesha. Ezinye iimpawu zinokuvela ebuntwaneni.
| Ixesha lokuqala kweempawu | Iimpawu ezibonakalayo |
|---|---|
| Ngexesha lobuntwana |
|
| Ebutsheni | Kukho amakhulu ee-polyps zamathumbu amakhulu. Nangona kunjalo, ezi zisenokungabonakalisi zimpawu ekuqaleni. Xa kuvela iimpawu, isifo sisenokuba sihambele phambili kakhulu. |
Into ebalulekileyo kukuba xa kuvela iimpawu ze-colon polyps, esi sifo sisenokuba sihambele phambili kakhulu. Ngoko ke, ukuba kukho umntu kusapho lwakho onale meko, kubaluleke kakhulu ukuba uhlolwe kwangethuba.
Ziziphi ezinye iimeko ezinxulumene neGardner syndrome?
Umntu one-Gardner syndrome usengozini enkulu yokuba nezi meko zilandelayo:
- Amazinyo ongezelelweyo
- Ii-Osteomas (iithumba zamathambo)
- Iithumba ezibangelwa yiDesmoid - Nangona ezi zingengomhlaza, zinokukhula ngokukhawuleza kwaye zonakalise izicubu ezingqongileyo.
- Iithumba ezinamafutha (iiLipomas)
- Iifibroma
- I-Adenomas - Iithumba ezingezizo ezomhlaza ezikhula kwiindlala.
- Ii-cysts ze-epithelial
- Imeko echaphazela i-retina yeliso (i-CHRPE - i-congenital hypertrophy ye-retinal pigment epithelium)
- Umhlaza wesisu
- Umhlaza wesibindi
- Umhlaza wamathumbu amakhulu
Kutheni oku kusenzeka? Yintoni unobangela?
Isizathu soku sisiphene kwenye yezakhi zofuzo zethu. Ngokuchanekileyo, kukho i-gene ebizwa ngokuba yi-APC gene . Umsebenzi wayo ophambili kukulawula iiseli emzimbeni wethu ukuba zingahlukani kwaye zingaphindaphindani ngokukhawuleza. Kanye njengeebhuleki emotweni. Izakhi zofuzo ezifana nale zibizwa ngokuba yi-tumor suppressor genes , oko kuthetha ukuba zithintela ukwakheka kwezakhi zofuzo.
Umntu one-Gardner syndrome une-APC gene engasebenzi kakuhle. Oku kuthetha ukuba i-brake elawula ukwahlulwahlulwa kweeseli ayisebenzi. Ngenxa yoko, iiseli ziyahlukana ngokungalawulekiyo kwaye ziqale ukwenza ii-tumor kunye nee-polyps.
Ugqirha uxilonga njani esi sifo?
Ngenxa yokuba esi sifo sineempawu ezahlukeneyo, ugqirha usebenzisa iimvavanyo ezininzi ukusixilonga.
- Uvavanyo lwemfuza: Olu vavanyo lwenziwa ukuze kubonwe ukuba unesiphene na kwimfuza yakho ye-APC. Ugqirha wakho angacebisa oku, ingakumbi ukuba kukho umntu kusapho lwakho onesifo.
- Uvavanyo lwekhamera: Olu luquka ukufaka ikhamera encinci emzimbeni ukuze kuhlolwe ingaphakathi lamathumbu.
- I-Sigmoidoscopy
- I-Endoscopy
- I-Colonoscopy - Le yinto ebona ngokucacileyo ii-polyps kwikholoni.
Zithini iindlela zonyango zoku?
Unyango luxhomekeke kwiimpawu zakho.
Khawuthelekelele ukuba unamazinyo angaphezulu. Oko kungaba luphawu lokuqala lwesi sifo. Emva koko kuya kufuneka ugqirha wamazinyo asuse loo mazinyo aze alungise amanye amazinyo akho. Ukuba unezimila ezibuthathaka, ungafumana unyango olufana ne -chemotherapy ukuze zinciphe.
Nangona kunjalo, ingxaki ephambili neyona iyingozi ngesi sifo ziipolyps ezikhula kwikholoni. Kufuneka utyando ukuze kuthintelwe ukuba ezi ziguquke zibe ngumhlaza.
| Igama lotyando | Yintoni eyenziwayo |
|---|---|
| Utyando lweColectomy | Ukususwa kwenxalenye okanye lonke ikholoni. Olu tyando ludla ngokucetyiswa ukuba kukho malunga nama-polyps angama-20-30. |
| I-Proctocolectomy | Ukususwa kwenxalenye enkulu yamathumbu amakhulu kunye ne-rectum. |
Khumbula, olu tyando lolona hlobo lokuthintela ukwakheka kwee-polyps kumathumbu amakhulu zize zibe ngumhlaza.
Ngaba esi sifo sinokunyangeka ngokupheleleyo?
Ngelishwa, isifo sikaGardner asinakunyangwa ngokupheleleyo.
Nangona kunjalo, oku kungalawulwa kakuhle. Ngonyango olufanelekileyo kunye nokuhlolwa rhoqo, izifo ezinzulu ezifana nomhlaza zinokufunyanwa kwaye zinyangwe kwangethuba. Ngoko ke akukho mfuneko yokoyika.
Ngaba kunokwenzeka ukuba uphile ubomi obuqhelekileyo ngesi sifo?
Ewe, unako. Nangona kunjalo, kunokubakho utshintsho oluthile kwindlela ophila ngayo emva kotyando. Umzekelo, ukususwa kwekholoni yakho kuya kutshintsha indlela osila ngayo ukutya kunye nendlela ophuma ngayo indle. Kusenokufuneka ube nendlela eyahlukileyo kunye nebhegi ye-ostomy efakwe esiswini sakho ukuze indle idlule. Ugqirha wakho uya kukuchazela oku ngokweenkcukacha.
Utyando lokuthintela umhlaza wamathumbu amakhulu ukuba ungakhuli ngenxa yesi sifo lunokwandisa ixesha lokuphila. Olunye uphando lubonise ukuba i-100% yabantu abaye banqunyulwa i-proctocolectomy babesaphila emva kweminyaka emi-5.
Uzinyamekela njani?
Ukuphila neGardner syndrome kuthetha ukuphila nomngcipheko wokuba nomhlaza usemncinci. Akulula. Ukujongana nolo lwazi kunokuba nzima ngengqondo.
Kungoko ke, kubalulekile ukwenza uvavanyo lomhlaza ngexesha elifanelekileyo. Oku kuthetha ukuba ukuba umhlaza uvela, unokubonwa kwaye unyangwe kwasekuqaleni.
Ukuba uziva uxinezelekile yile nto, thetha nogqirha wakho ngayo. Ukuba kuyimfuneko, funa iinkonzo zokunika iingcebiso.
Ndifanele ndimbone nini ugqirha?
Ukuba ubona naluphi na utshintsho olutsha emzimbeni wakho, umzekelo, iqhuma elitsha, okanye utshintsho kwindlela ohamba ngayo amathumbu akho, ingakumbi ukuba ubona igazi kwindle yakho , bona ugqirha ngoko nangoko.
Yeyiphi imibuzo omele uyibuze ugqirha wakho?
Xa ubona ugqirha wakho, ungalibali ukubuza le mibuzo.
- Ziziphi iindlela zonyango ezisetyenziswayo ngoku zokuthintela iimpawu zam?
- Ngaba ndiza kufuna utyando?
- Zeziphi iimvavanyo ekufuneka ndizenze? Kufuneka ndizenze kangaphi?
- Zeziphi iinguqu emzimbeni wam ekufuneka ndiziqwalasele ngokukodwa?
- Ingaba licebo elihle ukuba lonke usapho lwam luye kuvavanyo lwemfuza?
Isifo sikaGardner asiyonto yokoyika, kodwa yimeko ekufuneka ijongwane nayo ngononophelo kwaye ilawulwe ngokufanelekileyo. Ngeengcebiso zonyango ezifanelekileyo kunye novavanyo, ungaphila ubomi obusempilweni nobude.
Umyalezo Wokuya Ekhaya
- Isifo sikaGardner sisifo esingaqhelekanga esidluliselwa kubazali.
- Ingozi ephambili apha kukuba phantse zonke iipolyps ezenzeka kwikholoni zijika zibe ngumhlaza.
- Iimpawu zokuqala zoku zingabandakanya amazinyo angaphezulu avela ngexesha lobuntwana okanye iithumba ezingezizo zomhlaza ezikhula emzimbeni.
- Nangona oku kungenakunyangwa ngokupheleleyo, kunokulawulwa kakuhle ngokuhlolwa rhoqo kwezonyango kunye notyando.
- Ukuba wena okanye umntu osapho lwakho unezi mpawu, kubalulekile ukufuna ingcebiso kagqirha ngoko nangoko. Thetha ngokukhululekileyo nogqirha wakho malunga nempilo yakho yomzimba neyengqondo.
💬 Comments (0)
Akukho zimvo zithunyelweyo okwangoku. Faka uluvo lwakho apha okokuqala.
Faka uluvo lwakho