Izinto ekufuneka uzazi ngeSifo seTrophoblastic sokukhulelwa (GTD)!

Usenokuba awuzange uve ngegama elithi Gestational Trophoblastic Disease (GTD). Kodwa yimeko enokwenzeka ngamanye amaxesha ngexesha lokukhulelwa. Ngamafutshane, luhlobo lwethumba elikhula esibelekweni sakho, indawo apho umntwana wakho akhula khona, kwaye linxulumene nokukhulelwa. Ngaba singathetha ngale nto ngokweenkcukacha?

Ezi thumba ziqala ukwenzeka kwiiseli ezibizwa ngokuba yi -trophoblasts . Ezi seli zihlala zikhula zibe yi-placenta ngexesha lokukhulelwa. Uyazi, i-placenta yeyona nto ibalulekileyo edibanisa umntwana nesibeleko sakho, inika ioksijini kunye nezondlo kumntwana ongaphakathi kwesibeleko sakho.

Nangona kunjalo, kule meko 'ye-GTD', endaweni yokuba ikhule ibe yi-placenta esempilweni, ezo seli ze-trophoblast (oko kukuthi, iiseli ezifana ne-placenta) zikhula ngendlela engaqhelekanga.

Amaxesha amaninzi, i-GTD iyenzeka kwangethuba ekukhulelweni, emva kokuba isidoda siqhamise iqanda. Sikwabiza oku ngokuthi ukukhulelwa kwe-molar . Kodwa nangona oku kubizwa ngokuba kukukhulelwa, ezi seli azikhuli zibe yi-embryo ekhula ibe ngumntwana. Uninzi lwexesha, ezi ziimeko ezingezizo zomhlaza (ezingentle). Nangona kunjalo, ezinye zazo zinokuba ngumhlaza kwaye zisasazeke kwizicubu kunye namalungu akufutshane. Into ebalulekileyo kukuba i-GTD yimeko enokunyangwa. Uninzi lwabantu lunokukhulelwa okusempilweni emva kwesi sifo.

Ziziphi iimeko ezinokwenzeka apho i-GTD inokwenzeka khona?

Sihlala sithi i-GTD iyenzeka xa umntu ekhulelwe. Nangona kunjalo, le meko inokwenzeka nangamanye amaxesha:

• Emva kokuphuphuma kwesisu, okanye emva kokukhupha isisu.
• Emva kokukhulelwa kwityhubhu. Oko kukuthi, xa iqanda elivundisiweyo lingena kwityhubhu ye-fallopian endaweni yokuyifaka kwisibeleko.
• Kwanasemva kokukhulelwa okuqhelekileyo, kunokwenzeka rhoqo.

Ziziphi iintlobo ze-GTD? Makhe sibone ke?

Kukho iintlobo ezahlukeneyo ze-`GTD`. Iimpawu ziyahluka ngokuxhomekeke kuhlobo lwazo.

Ukukhulelwa kwe-Hydatidiform mole okanye i-molar

Olu lolona hlobo luqhelekileyo lwe-GTD. Lukwabizwa ngokuba yi-molar pregnancy . Oku kuxa, endaweni ye-placenta okanye i-embryo, kuvela i-cyst efana nediliya esibelekweni sakho. Ungaziva ukhulelwe, kwaye uvavanyo lokukhulelwa lunokuba ne-positive. Nangona kunjalo, i-ultrasound scan ayizukubonisa umntwana osakhulayo. Uvavanyo lokukhulelwa lubonakala lune-positive ngenxa yehomoni yokukhulelwa eveliswa yi-placenta. Kukho iintlobo ezimbini ze-hydatidiform moles: i-complete kunye ne-partial hydatidiform moles. Uninzi lokukhulelwa kwe-molar alunamhlaza.

Uphawu oluqhelekileyo lokukhulelwa kwe-molar kukopha okungaqhelekanga kwilungu lobufazi kwasekuqaleni kokukhulelwa. Oku kukopha kunokuba bomvu okanye kube mdaka ngamanzi. Ngamanye amaxesha kunokuhamba nentlungu yesisu.

Ukukhulelwa kwe-molar okungapheliyo/okungenayo

Oku kuthathwa njengokukhulelwa kwe-molar. Olu hlobo lwe-invasive mole lunokukhula lube yimisipha yesibeleko. Ngokungafaniyo nezinye iintlobo zokukhulelwa kwe-molar, ezi-invasive moles zihlala zinomhlaza. Ukuba azinyangwa, ezi seli zomhlaza zihlala zihlala kwimisipha yesibeleko, kodwa ngamanye amaxesha zinokusasazeka kwezinye iindawo zomzimba okanye kwizicubu.

I-Choriocarcinoma

I-Choriocarcinoma luhlobo lwe-GTD olukhula ngokukhawuleza nolunomhlaza. Luqala kwi-membrane yesibeleko sakho kwaye lunokusasazeka kwamanye amalungu omzimba, njengelungu lobufazi bakho, imiphunga, izintso, isibindi, kunye nengqondo. Le yimeko engaqhelekanga kakhulu, kodwa inokwenzeka kakhulu kubantu abakhe bakhulelwa i-molar ngaphambili.

Abanye abantu basenokungabi nazo kwaphela iimpawu. Kodwa kwabo baneempawu, uphawu oluqhelekileyo kukopha okungaqhelekanga kwilungu lobufazi emva kokuphuma kwesisu, ukukhupha isisu, okanye ukukhulelwa kwemihlathi. Abanye abantu banokuba neentlungu zesisu, igazi emchameni, okanye igazi elisesitulweni.

I-Placental site trophoblastic tumor (PSTT)

I-Placental site trophoblastic tumor (PSTT) luhlobo olungaqhelekanga lwe-GTD. Ikhula apho i-placenta inamathela khona kwisibeleko. I-PSTT ikhula kancinci kakhulu. Ke ngoko, kungathatha iminyaka emva kokukhulelwa ukuba iimpawu zibonakale. I-PSTT inokusasazeka kwimisipha yesibeleko, imithambo yegazi, imiphunga, i-pelvis, kunye ne-lymph nodes, ngoko ke kufuneka unyango olusebenzayo.

I-Epithelioid trophoblastic tumor (ETT)

Olu luhlobo olungaqhelekanga kakhulu lwe-'GTD' olunomhlaza. Njenge-'PSTT', lunokusasazeka luye emiphungeni. I-'ETT' inokukhula emva kweminyaka emininzi yokukhulelwa.

Ixhaphake kangakanani le meko?

E-United States, kuthiwa i-GTD iyenzeka kukukhulelwa okumalunga ne-1 kwi-1,000. Uhlobo oluqhelekileyo lwe-GTD yi-hydatidiform moles, esixoxe ngayo ngaphambili. Iimeko ze-GTD ezinzulu ngakumbi, ezifana ne-choriocarcinoma, zenzeka kukukhulelwa okungaphantsi kwe-1 kwi-20,000. Oku kuthetha ukuba azixhaphakanga kakhulu.

Ngaba i-GTD ingabulala?

Iimeko ezininzi ze-'GTD', ingakumbi xa zifunyenwe kwangethuba, zinokunyangwa kwaye zinyangeke ngokupheleleyo.Nangona kunjalo, kwiimeko eziphambili, i-GTD inokubulala. Yiyo loo nto ukuxilongwa kwangoko kunye nonyango kubalulekile.

Zithini iimpawu ze-GTD?

Abanye abantu abane-GTD basenokungabi nazo naziphi na iimpawu kwaphela. Abanye banokuba neempawu ezifana nezo zokukhulelwa okanye ezinye izifo/iimeko. Ukuba unayo nayiphi na kwezi mpawu, qiniseka ukuba ubona ugqirha wakho:

• Ukuba ukopha okungacwangciswanga kwilungu lobufazi, okanye ukopha okungahambelaniyo nokuya kwakho exesheni ngenyanga.
• Ukuba isibeleko sakho sivakala sikhulu kunokuba bekulindelwe ngexesha lokukhulelwa kwakho.
• Ukuba unentlungu esiswini okanye kwindawo ye-pelvic.
• Ukuba isicaphucaphu nokuhlanza kwenzeka ngaphambi kwexesha elilindelweyo ngexesha lokukhulelwa.
• Ukuba unoxinzelelo lwegazi oluphezulu kwasekuqaleni kokukhulelwa, okanye ukuba amalungu akho avuvukile.
• Ukuba uqhubeka nokopha kwilungu lobufazi, nokuba emva kokuba nomntwana okanye emva kokuphuphuma kwesisu.

Isifo seTrophoblastic sokukhulelwa ngamanye amaxesha sinokubangela ukusebenza kakhulu kwe-thyroid . Ukuba oku kuyenzeka, unokufumana iimpawu ezifana nezi:

• Isantya sentliziyo siyanda.
• Ukungcangcazela.
• Ukuhla ukusinda.
• Ukubila.

Zithini izizathu zokukhulelwa kwe-molar?

Ngamafutshane, xa ukhulelwe ngendlela eqhelekileyo, xa iqanda livundiswa yindoda, liqulathe lonke ulwazi olufunekayo ukuze kwenziwe umbungu kunye ne-placenta. Sibiza olu qokelelo lwasekuqaleni lweeseli ngokuthi yi-blastocyst . Olu mbungu yinto ekhula kamva ibe yi-fetus. Umaleko weseli ye-trophoblast uba yinxalenye ye-placenta kwaye unceda i-blastocyst ukuba inamathele eludongeni lwesibeleko.

Nangona kunjalo, xa ukhulelwe i-molar, i-embryo ayikhuli kakuhle kuba ukuchumisa akuzange kwenzeke. Endaweni yoko, iiseli ze-trophoblast zikhula zibe ziithumba endaweni ye-placenta ephilileyo. Le yeyona nto ibangela oku.

Ungayichonga njani i-GTD?

Ugqirha wakho uza kuxilonga i-GTD ngokuthatha imbali yakho epheleleyo yezonyango, enze uvavanyo lomzimba, aze enze ezinye iimvavanyo ukujonga ngaphakathi kwesibeleko sakho. I-GTD inokuxilonga ngoku:

• Uvavanyo lwe-pelvic: Ugqirha ufaka iminwe eneeglavu kwilungu lobufazi aze ajonge iimpawu zesifo, ezinje ngamaqhuma okanye uburhabaxa, okanye ubungakanani besibeleko.
• I-ultrasound scan: Oku kusebenzisa amaza esandi ukuthatha imifanekiso yamalungu akho angaphakathi. Ukuba ugqirha wakho urhanela ukuba i-GTD iyasebenza, i-transvaginal ultrasound iya kuthatha imifanekiso ye-pelvis yakho kunye nesibeleko.
• Uvavanyo lwegazi:Ukunceda ekuxilongeni i-GTD, kwenziwa uvavanyo lwegazi ukulinganisa amanqanaba ezinto ezithile emzimbeni wakho. Umzekelo, umfazi okhulelweyo one-GTD unokuba namanqanaba aphezulu kakhulu ehomoni ebizwa ngokuba yi -human chorionic gonadotropin (hCG) kunomfazi okhulelweyo ongena-GTD. Ukuba umhlaza usasazeke kwezinye izicwili okanye amalungu omzimba, umzimba wakho unokuvelisa izinto ezininzi okanye ezimbalwa ukubonisa isifo.

Ukuchonga amanqanaba esi sifo

Emva kokuba ufunyaniswe une-GTD, ugqirha wakho unokuyalela iimvavanyo ezongezelelweyo ukuze abone ukuba umhlaza usasazeke kwamanye amalungu omzimba wakho. Ukulinganisa izigaba zesifo yinkqubo yokufumanisa ukuba umhlaza usasazeke kangakanani kwaye ungakanani. Ezi ziphumo zinceda oogqirha ukuba bamisele ukuba loluphi udidi lomhlaza onalo.

Amanqanaba omhlaza abhalwa ngamanani esiRoma njengo-I, II, III, kunye no-IV. Okukhona inani liphezulu, kokukhona umhlaza usasazeka kakhulu.

Uvavanyo olusetyenziselwa ukufumanisa izigaba ze-`GTD` lungaba:

• I-CT scan (i-computed tomography - i-CT scan): Oku kusebenzisa uthotho lwee-X-rays kunye nekhompyutha ukwenza umfanekiso wezicubu namathambo onemilinganiselo emithathu (3D).
• I-MRI scan (iMagnetic resonance imaging - i-MRI): Oku kusebenzisa imagnethi kunye namaza erediyo ukwenza imifanekiso eneenkcukacha zomzimba wakho. Ugqirha angafaka into ebizwa ngokuba yi-gadolinium emithanjeni yakho, kuba le nto yenza iiseli zomhlaza zibonakale ngakumbi emfanekisweni.
• I-X-reyi yesifuba: Oku kusebenzisa umqadi wemitha ojolise ngqo ukuhlola imiphunga yakho, amanye amalungu angaphakathi esifubeni sakho, kunye namathambo.

Iphathwa njani i-GTD?

Iindlela zonyango lweSifo seTrophoblastic sokukhulelwa ziyahluka. Kukho izinto ezininzi ezisichaphazelayo. Ezifana nezi:

• Uhlobo lwe-`GTD`, ubungakanani bethumba, kunye nendawo elikuyo.
• Nokuba ithumba lisasazekile, okanye likwinqanaba elingakanani.
• Nokuba ithumba lenzekile ngexesha lokukhulelwa, okanye emva kokuphuma kwesisu okanye ukuzala.
• Impilo yakho iyonke.
• Imbali yakho yezonyango kunye nokuba ukhe wanyangwa i-GTD ngaphambili.
• Izicwangciso zakho zokuba nabantwana.

Ugqirha wakho uza kugqiba unyango olufanelekileyo kwimeko yakho. Nazi ezinye iindlela zonyango ezithile ze-GTD:

• Utyando: Utyando lokususa izicubu ezingaqhelekanga kunye neeseli kwisibeleko. Olona tyando luqhelekileyo lwe-GTD kukuvulwa nokususwa kwesibeleko (D&C) . Oku kubandakanya ukuvula umlomo wesibeleko kunye nokucoca isibeleko.
• Unyango lweKhemotherapy: Unyango lweKhemotherapy, okanye "ikhemo," kukusetyenziswa kweziyobisi ukutshabalalisa iiseli zomhlaza.
• Unyango ngemitha:Unyango lwemitha lusebenzisa imisebe yamandla enamandla ukubulala iiseli zomhlaza kunye nokunciphisa iithumba.
• Ukususwa kwesibeleko: Ukususwa kwesibeleko yindlela yotyando esusa isibeleko sakho. Ngamanye amaxesha, nezinye izitho zomzimba, ezifana neetyhubhu ze-fallopian kunye nama-ovari, zinokususwa.

Wena nogqirha wakho nifanele nixoxe ngonyango olufumanekayo, kunye neengozi kunye nemiphumo emibi yolo nyango.

Ngaba i-GTD ingaphinda ivele kwakhona?

Ewe, iSifo seTrophoblastic sokukhulelwa sinokuphinda sibuye. Ngokuxhomekeke kuhlobo lwe-GTD owawunayo ekuqaleni nendlela owasabela ngayo kunyango, kukho umngcipheko omncinci wokuphinda ubuye. Yiyo loo nto oogqirha beza kuqhubeka bekujonga emva konyango.

Ndingaba nomntwana emva kwe-GTD?

Ewe, ngokuqinisekileyo! Uninzi lwabantu abanembali ye-'GTD' banokuqhubeka nokukhulelwa okuqhelekileyo nokusempilweni. Nangona kunjalo, ngokuxhomekeke kwimbali yakho, ugqirha wakho unokucebisa uvavanyo olongezelelweyo ekukhulelweni okulandelayo.

Ngaba i-GTD ingathintelwa?

Akukho ndlela yokuthintela iSifo seTrophoblastic sokukhulelwa. Le yinto esingenakuyilawula.

Izinto ezibangela umngcipheko wokuphuhlisa i-GTD

Nangona iSifo seTrophoblastic sokukhulelwa sisifo esingaqhelekanga, kukho izinto ezithile ongenakukwazi ukuzilawula ezinokunyusa umngcipheko wakho wokuba naso. Ezi zinto ziquka:

• Ubudala bakho. Abantu abangaphezu kweminyaka engama-35 ubudala kunye nabo bangaphantsi kweminyaka engama-20 ubudala basengozini enkulu kancinci yokuhlaselwa yi-GTD.
• Ukuba ukhe wakhulelwa umhlathi ngaphambili.
• Ukuba kukho umntu kusapho oye wakhulelwa emhlane, oko kuthetha ukuba imbali yosapho ibandakanyekile.

Ngoko ke, zeziphi izinto ekufuneka sizikhumbule kuzo zonke ezi zinto?

Xa ufumanisa ukuba unesifo sokukhulelwa (i-GTD), kuyinto eqhelekileyo ukuziva usoyika, ukhathazekile, kwaye ulusizi. Kunokuba nzima nokujamelana nokulahlekelwa kukukhulelwa kwakho kunye nokufumana ukuxilongwa okuntsonkothileyo ngaxeshanye.

Kodwa khumbula, ugqirha wakho uza kwenza iimvavanyo ezahlukeneyo, aqonde imeko yakho ngqo, aze amisele unyango olufanelekileyo. Into ebalulekileyo kukuba kwiimeko ezininzi, 'i-GTD' yimeko enokunyangwa. Amathuba akho okukhulelwa kwakhona (ukuba uyafuna) nawo mahle kakhulu.

Funa inkxaso kusapho lwakho, abahlobo, kunye noogqirha ngeli xesha linzima. Kwaye ungabi nanto yakwenza, kwaye ungoyiki ukubuza imibuzo. Awuwedwa, sonke sikunye nawe.

Isifo se - Gestational trophoblastic, i-GTD, ukukhulelwa kwe-molar, umhlaza wesibeleko, i-placenta, i-choriocarcinoma, iingxaki zokukhulelwa