Ingaba unengxaki yokuba amanqanaba e-calcium aphantsi emva kotyando? Isenokuba yi-'Hungry Bone Syndrome'!

Njengoko usenokuba uyazi, emva kotyando oluthile, ingakumbi olo lususa i-thyroid gland entanyeni okanye kwi-parathyroid glands ezikufutshane, umzimba unokufumana iintlobo ezimbalwa zokungakhululeki. Abanye abantu banokuziva bediniwe ngendlela engaqhelekanga, babe neentlungu zomzimba, okanye bazive bedidekile. Ngoko ke ukuba wena okanye umntu omaziyo uhlangabezana nento efana nale, isenokuba ibangelwa yimeko esiza kuthetha ngayo namhlanje ebizwa ngokuba yi-'Hungry Bone Syndrome'. Eli gama livakala lingaqhelekanga, akunjalo? Usenokuba ucinga, "Kuthetha ukuthini ukuba namathambo alambileyo?" Makhe sijonge ukuba yintoni, ngamazwi alula.

Yintoni i-'Hungry Bone Syndrome'?

Ngamafutshane, iHungry Bone Syndrome yimeko apho amanqanaba e-calcium egazini lakho ehla ngequbuliso kakhulu. Oogqirha bayibiza le nto ngokuthi "yiHypocalcemia". Le meko idla ngokubonakala emva kotyando kwi-parathyroid glands. Ubusazi ukuba i-parathyroid glands ibaluleke kakhulu ekulawuleni i-calcium emizimbeni yethu?

Abantu abanesi sifo 'sokulamba amathambo' basenokungabi namanqanaba aphantsi e-calcium kuphela, kodwa ngamanye amaxesha banokuba namanqanaba aphantsi e-magnesium (`(Hypomagnesemia)`) kunye ne-phosphorus (`(Hypophosphatemia)`) egazini labo. Ezi ziminerali ezibalulekileyo ezifunekayo emizimbeni yethu.

Kodwa akukho nto ifanele ixhalabise ngayo. I-'Hungry Bone Syndrome' yimeko enokunyangeka kwaye inyangeke . Eyona nto ibalulekileyo kukuyiqaphela kwangethuba kwaye uqale unyango.

Ixhaphake kangakanani le meko?

Abaphandi abanalo ulwazi oluchanekileyo lokuba le 'hungry bone syndrome' ixhaphake kangakanani, njengoko inokwahluka kumntu nomntu.

Nangona kunjalo, ezinye izifundo zibonise ukuba phakathi kwabantu abayi-4 ne-13 kwabali-100 abaye basuswa i-parathyroid ngenxa yemeko ebizwa ngokuba yi-primary hyperparathyroidism bakhula nale meko. Kwakhona, ezinye iingxelo zithi emva kotyando lwe-secondary and tertiary hyperparathyroidism, amathuba okuba le meko ikhule anokuba ngama -20 ukuya kuma-70 kwabali-100. Ngoko ke, kubonakala ngathi oku kunokuba yinto eqhelekileyo kwezinye iimeko.

Zithini iimpawu ze-'Hungry Bone Syndrome'?

Iimpawu ze-'Hungry Bone Syndrome' zifana kakhulu nezo zibangelwa yi-calcium ephantsi egazini (i-Hypocalcemia). Ezi zinokuba zincinci njengeqhubu elincinci kwabanye abantu, ukuya kuthi ga ngoku zinzima njengokudideka okanye ukuxhuzula kwabanye. Nazi ezinye zeempawu:

• Ukuqengqeleka okanye ukutsala inyama: Ukuziva ngathi inyama esemilenzeni okanye ezingalweni iqengqeleka nje.
• Ubuthathaka bemisipha: Ukuziva ungenabomi kwaye udiniwe kakhulu ukuba ungenza nantoni na.
• Intlungu yamathambo: Ukuziva ngathi amathambo emzimbeni ayabuhlungu.
• Ukudinwa kakhulu: Ukudinwa okungapheliyo nokuba sele ulele.
• Ukudideka: Ubunzima bokugxila, ukungazi ukuba wenze ntoni.
• Iingxaki zenkumbulo: Ukulibala izinto.
• Ukucaphuka okanye ukucaphuka: Ukucaphuka ngezinto ezincinci, ukuziva ungakhululekanga.
• Uxinzelelo: Ukuziva ulusizi kwaye uphelelwe lithemba.
• Ukuba ndindisholo emilebeni, elulwimini, kwiiminwe, kunye/okanye ezinyaweni: Ezi ndawo zivakala ngathi ndindisholo, okanye ngathi ziimbovane ziyabaleka.
• Ubunzima bokuphefumla ngenxa yokuxinana kwemisipha yomphimbo (`(Laryngospasm)`): Oku kuyingozi kancinci, kwenza kube nzima ukuphefumla.
• Ukuqina kwemisipha kunye nokuxhuzula (`(Tetany)`): Imeko apho izihlunu zomzimba ziqina kwaye zixhuzula.
• Ukuxhuzula: Olu luphawu olubi kakhulu.

Kunye nezi mpawu, njengoko bekutshiwo ngaphambili, amanqanaba aphantsi e-magnesium kunye ne-phosphorus egazini (`(Hypomagnesemia)` kunye `(Hypophosphatemia)`) nawo anokubakho. Iimpawu zezi meko zifana kakhulu nezo ze-calcium ephantsi. Zinokubangela iingxaki zemisipha, ukuxhuzula, kunye nokubetha kwentliziyo okungaqhelekanga (`(Arrhythmia)`).

I-Hungry bone syndrome idla ngokuvela kwiiyure ezili-18 emva kotyando lwe-parathyroid okanye lwe-thyroid .

Kutheni le nto le 'Hungry Bone Syndrome' isenzeka?

Kukho izizathu ezininzi eziphambili ze-'Hungry Bone Syndrome':

• Emva kotyando lwe-parathyroid (i-Parathyroidectomy) kwi-hyperparathyroidism yokuqala okanye yesibini.
• I-Thyrotoxicosis yimeko eyenzeka emva kokususwa kwe-thyroid ngokupheleleyo.
• Xa umhlaza weprostate usasazeka emathanjeni (usasazeka kwi-metastasized).

Ukuze siqonde kakuhle ukuba kutheni oku kusenzeka, kubalulekile ukuqonda kancinci malunga nendlela amanqanaba e-calcium alawulwa ngayo emizimbeni yethu.

Khawuthelekelele, emva kwe-thyroid gland yakho entanyeni yakho, kukho amadlala amane amancinci abizwa ngokuba yi-parathyroid glands. La madlala avelisa i-hormone ebizwa ngokuba yi-parathyroid hormone (PTH) . Umsebenzi ophambili wale hormone ye-PTH kukulawula inqanaba le-calcium egazini (hayi emathanjeni, kodwa egazini). I-PTH ikwanceda ukulawula amanqanaba e-phosphorus (kwakhona yiminerali) kunye ne-vitamin D (kwakhona yi-hormone) egazini nasemathanjeni.

Ngoko ke, xa umzimba wakho uziva ukuba inqanaba le-calcium egazini lakho liphantsi, amadlala e-parathyroid akhupha i-hormone i-PTH. Le PTH iyahamba ize ikhuphe inani elincinci le-calcium emathanjeni ize iyongeze egazini. Emva koko inqanaba le-calcium egazini libuyela kwisiqhelo.

Ngoku, khawucinge ukuba umntu unee-parathyroid glands ezisebenza kakhulu, aze atyandwe ukuze azisuse. Okwenzekayo kukuba amanqanaba e-PTH hormone awayephezulu kakhulu ngaphambili ehla ngequbuliso. Ngamanye amaxesha, xa kwenziwa utyando lwe-thyroid, ukuba ii-parathyroid glands ezikufutshane zonakele ngengozi, amanqanaba e-PTH nawo anokwehla.

Xa amanqanaba e-PTH ehla ngequbuliso, ubungakanani be-calcium emathanjeni amadala aphinda afakwe egazini (`(Resorption)`) buyancipha, kwaye ubungakanani bokwakheka kwamathambo amatsha (`(Bone Formation)`) buyanda. Oku kubangela ukuba amathambo "angabi naso" i-calcium. Yiyo loo nto oku kubizwa ngokuba yi-'hungry bone syndrome'.

Oku kwenzeka xa umhlaza weprostate usasazeka emathanjeni. Apho, umsebenzi weeseli zokwakha amathambo (`(umsebenzi we-Osteoblastic)` uyanda, ngoko ke amathambo afuna i-calcium engaphezulu.

Ngubani osengozini enkulu yokuba ne-'Hungry Bone Syndrome'?

Abanye abantu banamathuba amaninzi okuba nale meko. Makhe sijonge ukuba bangoobani:

• Amanqanaba aphezulu kakhulu e-parathyroid hormone (PTH) egazini.
• Ukwanda kwamanqanaba e-alkaline phosphatase egazini.
• Amanqanaba e-calcium egazini adla ngokuba phantsi.
• Ukuba nokungabikho kwevithamini D.
• Ukwenza utyando lwe-thyroid kunye ne-parathyroid ngaxeshanye.
• Amanqanaba aphezulu e-urea nitrogen (BUN) egazini.
• Ukutyeba kakhulu, oko kukuthi, ukutyeba kakhulu.
• Ukususwa ngotyando kwe-parathyroid gland enkulu kuneqhelekileyo.
• Ukusasazeka kweeseli zomhlaza emathanjeni (Metastatic tumors of the bones).
• Ukubakho kwezifo ezinxulumene namathambo ezifana neethumba ezimdaka kunye ne-osteitis fibrosa cystica.

Abantu abanezi zinto zinobungozi banamathuba amaninzi okufumana 'i-hungry bone syndrome'.

Oogqirha bayifumana njani le nto?

Ugqirha uhlala eqala ngokufumanisa ukuba unayo na i-'hungry bone syndrome' ngokwenza uvavanyo lwegazi lwe-calcium. Ngokuqhelekileyo, ukuba inqanaba le-calcium egazini lakho lingaphantsi kwe-8.4 mg/dL kangangeentsuku ezingaphezu kwezine, ithathwa njengengozi ye-'hungry bone syndrome'.

Ayisiyiyo loo nto kuphela, kodwa ugqirha wakho unokwenza nezinye iimvavanyo ezimbalwa ukuze abone ukuba le meko ichaphazele ezinye iinkalo zempilo yakho:

• Ezinye iimvavanyo zegazi: Igazi lakho linokuvavanywa ukuba lifuna i-magnesium, i-phosphorus, i-parathyroid hormone (PTH), kunye/okanye amanqanaba e-vitamin D.
• I-EKG (i-Electrocardiogram): Olu vavanyo lulinganisa isigqi sentliziyo yakho ngokuncamathisela ii-electrode esifubeni sakho. Oku kubalulekile kuba i-calcium ephantsi egazini (i-hypocalcemia) kunye 'ne-hungry bone syndrome' zinokubangela ukubetha kwentliziyo okungaqhelekanga.
• Uvavanyo lomfanekiso wamathambo: Olu vavanyo lunokujonga iingxaki ngamathambo akho, ezinje ngokwaphuka kwamathambo, ukukhubazeka, okanye iithumba.

Ziziphi iindlela zonyango lwe-'Hungry Bone Syndrome'?

Ungakhathazeki, kukho unyango olufanelekileyo loku. Injongo ephambili yonyango kukubuyisela amanqanaba e-calcium egazini lakho kwinqanaba elisempilweni. Kwiimeko ezininzi, uya kufumana olu nyango ngelixa usesibhedlele. Unyango lunokuquka:

• Ukunika i-calcium ngemithambo yegazi (`(IV Calcium - Calcium Gluconate)`): Oku kunceda ukubuyisela ngokukhawuleza amanqanaba e-calcium.
• Izithako zeCalcium ezisetyenziswa ngomlomo (iCalcium Citrate okanye iCalcium Carbonate): Ezi zinikwa ukugcina amanqanaba ecalcium.
• Izongezo zeVithamin D ezithethwa ngomlomo: IVithamin D ibalulekile emzimbeni ukuze ufumane icalcium.
• Ukutshintshwa kweMagnesium: Ukuba amanqanaba eMagnesium aphantsi, nawo loo nto kufuneka ilungiswe.

Oogqirha baza kuhlola imeko yakho baze bakhethe unyango olufanelekileyo kuwe.

Kuza kuthatha ixesha elingakanani ukuze umntu aphile kule meko? Lithini ikamva?

Iindaba ezimnandi zezokuba le meko, 'iHungry Bone Syndrome', phantse inganyangeka ngokupheleleyo . Oko kuthetha ukuba ingqikelelo ilungile kakhulu.

Nangona kunjalo, nangona unyango lukhona, ixesha elithathwayo ukuze le meko iphele ngokupheleleyo linokwahluka. Abanye abantu bayachacha kwiintsuku ezimbalwa, ngelixa abanye banokuthatha iinyanga ezininzi. Kwiimeko ezingaqhelekanga kakhulu, inokuhlala ixesha elide ukuya kuthi ga kunyaka.

Okubaluleke kakhulu, ukuba ayinyangwa, i-hypocalcemia enzima inokukhokelela kwiingxaki ezisongela ubomi ezifana nokuxhuzula. Ke ngoko, kubalulekile ukufuna unyango ngokukhawuleza ukuba kuvela iimpawu.

Ngaba i-'Hungry Bone Syndrome' ingathintelwa?

Ekubeni 'i-hungry bone syndrome' inokwenzeka emva kotyando lwe-parathyroid (`(Parathyroidectomy)`) okanye utyando lwe-thyroid (`(Thyroidectomy)`), oogqirha bazama ukuthatha amanyathelo okuthintela oku kwanangaphambi kotyando. Makhe sibone ukuba zithini:

• Uvavanyo lwangaphambi kotyando: Ngaphambi kotyando , ugqirha wakho uza kujonga ubuninzi beeminerali emathanjeni akho, amanqanaba e-calcium egazini, amanqanaba e-phosphate, amanqanaba e-PTH, kunye namanqanaba e-vitamin D. Olu vavanyo lunokunceda ugqirha wakho ukuba aqinisekise ukuba usemngciphekweni wokuba ne-'hungry bone syndrome'.
• Amanyathelo okuthintela:Ukuba usengozini enkulu yokuba ne-'hungry bone syndrome', ugqirha wakho unokucebisa ukuba uthathe izongezo okanye amayeza okugcina amanqanaba akho e-vitamin D kunye ne-calcium ngaphambi kotyando. Oku kunokunceda ukunciphisa amathuba kunye/okanye ubukhali be-'hungry bone syndrome'.
• Ukubeka iliso emva kotyando: Emva kotyando, iqela lesibhedlele liza kujonga rhoqo amanqanaba e-calcium, i-phosphate, i-magnesium, kunye ne-PTH egazini lakho. Oku kwenzelwa ukuba ukuba unesifo 'se-hungry bone syndrome', sichongwe kwangethuba kwaye unyango luqalwe ngoko nangoko.

Nangona kunjalo, nangona zonke ezi ndlela zokulinganisa, ngamanye amaxesha i-'hungry bone syndrome' inokubakho. Abaphandi abakaqiniseki ukuba kutheni oku kusenzeka.

Ndifanele ndibonane nogqirha nini?

Ukuba ukhe watyandwa i-parathyroid okanye i-thyroid waza kamva waba neempawu ze-calcium ephantsi egazini (`(Hypocalcemia)`) esizixubushileyo ngaphambili, ezifana nokuqaqamba kwemisipha, ukuziva ubuthathaka, utshintsho engqondweni (njengokudideka), kunye nokungacaci kwemilebe neminwe, ngokuqinisekileyo kufuneka ubone ugqirha ngokukhawuleza.** 'I-Hungry bone syndrome' kunye ne-`(Hypocalcemia)` zinokwenzeka emva kotyando lwe-parathyroid kunye/okanye i-thyroid, zinokuphela emva kweentsuku ezimbalwa, zize ziphinde zivele. Ke ngoko, kubaluleke kakhulu ukuqaphela nokuba luphawu oluncinci.

'I-Hungry bone syndrome' yimeko enokwenzeka emva kotyando lokususa i-parathyroid okanye i-thyroid glands. Iindaba ezimnandi zezokuba inokunyangeka kwaye inyangeke. Nangona kunjalo, kungathatha ixesha ukuba iphile ngokupheleleyo. Ekubeni ukwehla okukhulu kwamanqanaba e-calcium egazini kunokuba yingozi kwimpilo yakho, kungcono ukubona ugqirha kwangoko xa ubona iimpawu.

Umyalezo oya ekhaya

Ngoko ke, ngamafutshane, i-'Hungry Bone Syndrome' yimeko enokwenzeka emva kotyando kwi-parathyroid okanye kwi-thyroid gland. Eyona nto iyenzayo kukuba ubungakanani be-calcium egazini lomzimba buyancipha ngequbuliso. Oku kungenxa yokuba inqanaba le-parathyroid hormone (`(PTH)`) liyehla emva kotyando, nto leyo ebangela ukuba amathambo "afune" i-calcium.

Musa ukoyika ukuva oku, kuba 'iHungry Bone Syndrome' yimeko enokunyangeka kwaye inyangeke kakuhle.

Eyona nto ibalulekileyo kukuba ukuba unezinye zezi mpawu (ezifana nokuxhuzula kwemisipha, ukudinwa, ukuba ndindisholo), ungachithi xesha kwaye ubone ugqirha ngokukhawuleza. Ngale ndlela, unokuyibona imeko kwangethuba, uqale unyango olufunekayo ngokukhawuleza, kwaye uyinyange ngaphambi kokuba ibe yingxaki enkulu. Khumbula, ukunyamekela impilo yakho kusezandleni zakho.

"I-Hungry Bone Syndrome, i-Hungry Bone Syndrome, i-Calcium, i-Hypocalcemia, i-Parathyroid, utyando lwe-thyroid, i-PTH