Xa sijonga i-cholesterol yethu, sihlala sijonga kuphela "i-cholesterol elungileyo" (i-HDL) kunye "ne-cholesterol embi" (i-LDL), akunjalo? Kodwa ubusazi na ukuba kukho uhlobo olubaluleke kakhulu lwe-cholesterol abantu abaninzi abangathethi ngalo, kodwa olufihliweyo phakathi? Le yiLipoprotein(a), okanye i-Lp(a) ngamafutshane. Into ekhethekileyo ngale nto kukuba imiselwa ziijini zethu, oko kuthetha ukuba idluliselwa kwizizukulwana ngezizukulwana, endaweni yoko kuxhomekeke kwinto esiyityayo nesiyiselayo okanye esiyenzayo. Usenokuba ngumntu osempilweni kakhulu, kodwa inqanaba lakho le-Lp(a) linokuba phezulu kakhulu.
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Yintoni kanye kanye iLipoprotein(a)?
Ngamafutshane, le ikwalisuntswana eline-cholesterol egazini lethu. Kodwa ingxaki ngale nto kukuba inqanaba layo lixhomekeke kakhulu kwiijini zethu. Oku kuthetha ukuba ukuba umama wakho, utata wakho, okanye umntu kusapho lwakho unale meko, nawe unokuba nayo. Kuthiwa malunga nomntu omnye kwabahlanu emhlabeni wonke unezinga eliphezulu le-Lp(a).
Ingozi yoku kukuba ukuba namanqanaba aphezulu e-Lp(a) kwandisa kakhulu umngcipheko wokuhlaselwa sisifo sentliziyo kunye ne-stroke besebancinci. Uninzi lwexesha, abantu bafumanisa oku kuphela emva kokuba behlaselwe sisifo sentliziyo okanye i-stroke. Oku kungenxa yokuba iphaneli ye-lipid eqhelekileyo ayibonisi eli xabiso le-Lp(a). Ifuna uvavanyo olwahlukileyo.
Umzekelo, cinga ngebali likaBernadette, umfazi oneminyaka engama-66 ubudala ohamba malunga neekhilomitha ezili-10 ngosuku aze atye ukutya okusekwe kwizityalo, kuquka imifuno kunye ne-tofu. Amanqanaba akhe e-cholesterol ngokubanzi ayekwinqanaba elifanelekileyo, kodwa inqanaba lakhe le-Lp(a) laliphindwe kahlanu kunenqanaba lomngcipheko. Oku kwakubangelwa yimfuza yakhe. Bobabini umama wakhe noninakhulu basweleka ngenxa yesifo sentliziyo.
"Owona mceli mngeni mkhulu kum luxinzelelo lokuphila nale nto. Nangona ndiziva ndigula kancinci, ndicinga ukuba, 'Ngaba le yintlungu yentliziyo endiya kuba nayo?'" utshilo uBernadette.
Ingxaki kunye nethemba elitsha
Ukuza kuthi ga ngoku, akukho chiza lithile livunyiweyo lokunciphisa amanqanaba e-Lp(a). Oku kuthetha ukuba nangona besazi ukuba likho, abantu abaninzi baye baphila ngoloyiko, bengenakwenza nto ngalo. Kufana nokuba nebhombu yexesha emzimbeni wabo enokuqhuma nangaliphi na ixesha.
Kodwa, ngoku loo meko iza kutshintsha!
Abaphandi bezonyango okwangoku baphanda amayeza amatsha amahlanu abonakaliswe kwizifundo zokuqala ukuba anciphisa kakhulu amanqanaba e-Lp(a). Eli lithemba elikhulu kwizigidi zabantu abanamanqanaba aphezulu e-Lp(a). Njengoko umphandi ophambili uGqr. Steven Nissen esitsho, " Musani ukukhathazeka, izisombululo ziyeza. "
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Check Availability →Amayeza amva nje akwinqanaba lophando
La mayeza matsha asekwinqanaba lokugqibela lophando (izilingo zeklinikhi). Ukuba ayaphumelela, anokuba semarikeni kungekudala. Masibone ukuba zeziphi ezo ziyobisi kwaye ziphumelela kangakanani.
| Igama leziyobisi | Uphawu / Indlela yokubonelela | Iziphumo ezilindelekileyo |
|---|---|---|
| IPelacarsen | Inaliti enikwa kube kanye ngenyanga | Amanqanaba e-Lp(a) anokuncitshiswa malunga ne-80%. |
| I-Olpasiran | Isitofu sokugonya esinikwa rhoqo emva kweenyanga ezi-3 | Amanqanaba e-Lp(a) anokuncitshiswa ngaphezulu kwe-95%. |
| I-Lepodisiran | Isitofu esinye sokugonya esihlala sisebenza phantse unyaka wonke | Amanqanaba e-Lp(a) anokuncitshiswa malunga ne-94% aze agcinwe ixesha elide. |
| I-Zerlasiran | Isitofu sokugonya esingasetyenziswa rhoqo | Amanqanaba e-Lp(a) anokuncitshiswa malunga ne-86%. |
| IMuvalaplin | Ipilisi yemihla ngemihla | Amanqanaba e-Lp(a) anokuncitshiswa malunga ne-86%. |
Yintoni ekhethekileyo ngethebhulethi yeMuvalaplin?
Kwezi, abaphandi banethemba elikhulu ngeyeza elibizwa ngokuba yi-(Muvalaplin)'' kuba nangona amanye amayeza amane kufuneka anikwe njengeenaliti, eli lingathathwa njengepilisi yemihla ngemihla . Ke ngoko, linokuba lula ngakumbi kwizigulane, kwaye lisenokungabizi kakhulu.
Amanye amayeza asebenza ngokuthulisa i-gene ebangela ukuveliswa kwe-Lp(a). Kodwa le pilisi isebenza ngendlela eyahlukileyo. Iyayimisa imveliso yamasuntswana e-Lp(a) embindini. Oku kuyivumela ukuba isebenze ngaphandle kokuchaphazela isibindi kwaye isuswe emzimbeni ngokukhawuleza ukuba kukho naziphi na iziphumo ebezingalindelekanga.
Kutheni kufuneka sivavanye i-Lp(a)?
Njengoko ufunda eli nqaku, usenokuba uzibuza, 'Ngaba nam ndifanele ndihlolwe oku?' Impendulo ithi, ewe! Ngokuqinisekileyo kufuneka uqwalasele oku, ingakumbi ukuba umntu kusapho lwakho ukhe waba nesifo sentliziyo okanye istroke esemncinci .
I-National Lipid Association ngoku icebisa ukuba wonke umntu ahlolwe inqanaba lakhe le-Lp(a) ubuncinane kube kanye ebomini bakhe . Ngenxa yokuba yinto yemfuza, inqanaba alitshintshi kangako ebomini bonke. Ukuhlolwa nje kube kanye kwanele.
Olu luvavanyo lwegazi olulula kakhulu. Nangona kunjalo, ekubeni lungafakwanga kwingxelo eqhelekileyo ye-cholesterol, kufuneka ubuze ugqirha wakho ngokuthe ngqo malunga noku ngaphambi kokuba wenze olu vavanyo.
Ukwazi inqanaba lakho le-Lp(a) linyathelo lokuqala. Ukuba liphezulu, ungoyiki. Ngala mayeza matsha aza kuza kungekudala, uya kukwazi ukulawula umngcipheko wakho wokuhlaselwa sisifo sentliziyo kunye nestroke. Kude kube ngoko, kubalulekile ukugcina ezinye izinto ezinobungozi, ezifana noxinzelelo lwegazi oluphezulu, isifo seswekile, ukutshaya, kunye namanqanaba e-cholesterol ye-LDL, zilawulwa kakuhle.
Umyalezo Wokuya Ekhaya
- I-Lipoprotein(a), okanye i-Lp(a), luhlobo lwe-cholesterol olulawulwa ngokwemfuza kwaye lunyusa umngcipheko wesifo sentliziyo.
- Oku akubandakanyiwe kuvavanyo lwe-cholesterol oluqhelekileyo (iprofayili ye-lipid), ngoko ke kufuneka ubuze ugqirha wakho ngale nto kwaye uyihlolisise ngokukodwa.
- Ukuba kukho umntu kusapho lwakho oye waba nesifo sentliziyo esemncinci, kubaluleke kakhulu ukwenza olu vavanyo.
- Nangona okwangoku kungekho chiza lithile le-Lp(a), amayeza amaninzi abonisa iziphumo ezithembisayo kakhulu akwinqanaba lokugqibela lophando. Oku kuthembisa kakhulu.
- Ukuba ufumanisa ukuba inqanaba lakho le-Lp(a) liphezulu, musa ukoyika, thetha nogqirha wakho ngaloo nto, kwaye ulawule ezinye izinto ezibangela umngcipheko wesifo sentliziyo.
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