Ngaba uyayazi i-PCD? (I-Primary Ciliary Dyskinesia) Makhe sithethe ngale meko ingaqhelekanga!

Ngaba wakha weva ngemeko ebizwa ngokuba yi-'Primary Ciliary Dyskinesia' okanye `(Primary Ciliary Dyskinesia - PCD)`? Nangona eli gama lisenokuvakala lingaqhelekanga, le yimeko engaqhelekanga, kodwa ibaluleke kakhulu echaphazela inkqubo yethu yokuphefumla kunye nezinye iinkqubo zomzimba. Idla ngokuba yinto ekhoyo ekuzalweni. Ngoko ke, namhlanje siza kuthetha ngale PCD ngendlela elula onokuyiqonda.

Yintoni i-primary ciliary dyskinesia (PCD)?

Ngamafutshane, i-PCD yimeko eyenzeka xa izakhiwo ezincinci ezifana neenwele emzimbeni wethu ezibizwa ngokuba yi-cilia zingasebenzi kakuhle . Ezi cilia zincinci kangangokuba azibonakali emehlweni ethu. Khawuthelekelele ukuba ezi cilia zisebenza njengeentshayelelo ezincinci kwindlela yethu yokuphefumla, oko kukuthi, kwiindawo ezifana nempumlo, umphimbo, kunye nemiphunga.

Ngoko ke zenzani ezi cilia?

Ezi zakhiwo zincinci, ezifana neenwele ezibizwa ngokuba yi-cilia azifumaneki kuphela kwinkqubo yethu yokuphefumla, kodwa nakwezinye iindawo. Umsebenzi wazo ophambili kukususa izinto ezingafunekiyo ezifana neentsholongwane nothuli olungena emizimbeni yethu, kunye ne-mucus eqokelelana emzimbeni . Zikwenza oku ngokuhamba njengegagasi. Akupheleli apho, xa umntwana ekhula esibelekweni, ezi cilia zikwanceda amalungu omntwana ukuba abe kwiindawo ezifanelekileyo.

Ngoko ke, okwenzekayo kumntu one-PCD kukuba ezi cilia azisebenzi kakuhle. Oko kuthetha ukuba:

• Mhlawumbi obu bungakanani be-cilia abulunganga .
• Imo yazo isenokuba ayiqhelekanga .
• Mhlawumbi i-cilia iya kunyamalala .
• Okanye, banokuhambahamba ngokungathi baphambene, bengenalo naluphi na unxibelelwano .
• Okanye isenokungashukumi konke konke .

Sigula njani ngenxa ye-cilia engasebenzi kakuhle?

Xa ezi cilia zingasebenzi kakuhle, iingxaki ezahlukeneyo zempilo zinokubakho. Ezinye ziqala ekuzalweni, ngelixa ezinye zinokuvela kamva ebomini.

• Indawo engaqhelekanga yomzimba: Khawucinge nje, amalungu anjengentliziyo yethu, imiphunga, ipleyini, njl.njl. abekwe kwelinye icala endaweni yelasekunene. Ngamanye amaxesha, into ekufanele ukuba ibe kwicala lasekunene inokuba ngasekhohlo. Oku sikubiza ngokuba yi-"Situs Inversus" . Ngamanye amaxesha, amalungu anokujikwa ngokupheleleyo kwicala elingalunganga. Oku kunokwenzeka nokuba loo cilia ayisebenzi kakuhle.
• Isifo sokuphefumla esingapheliyo nesinzima: Le yeyona ngxaki iphambili ye-PCD. Xa i-cilia ingakwazi ukukhupha i-mucus, i-mucus iqokelelana emiphungeni nakwimibhobho yomoya. Oku kukhokelela ekukhwehleleni rhoqo, ekuxinaneni kwesifuba, nasekosulelekeni okukhulu . Oku kungonakalisa nemiphunga.
• Iingxaki zokuzala: Amadoda ane-PCD adla ngokuba nobunzima bokuzala abantwana, nto leyo ethetha ukuba asenokuba ngabangazaliyo . Abafazi banokuba neengxaki ezinkulu ngexesha lokukhulelwa, njengokukhulelwa okungaphandle kwesibeleko (apho i-embryo ifakwa ngaphandle kwesibeleko).Kunokwenzeka.

Yintoni ebangela i-PCD?

Le yimeko yemfuza . Oko kukuthi, ibangelwa lutshintsho oluthile okanye utshintsho kwiimfuza oludluliselwa kumzali ukuya emntwaneni. Kukho iintlobo ezahlukeneyo zenguqu kwimfuza ezibangela esi sifo.

Ziziphi iimpawu ze-primary ciliary dyskinesia?

Iimpawu zihlala zibonakala xa umntwana ezalwa, kwaye zinokukhula kancinci kancinci ngokuhamba kwexesha.

Iimpawu ze-PCD ezinokubonwa xa umntwana ezalwa:

• Ubunzima bokuphefumla : Umntwana unokuba nobunzima bokuphefumla kwangoko emva kokuzalwa.
• Ukuxinana kwempumlo : Impumlo yakho isenokuziva ivalekile rhoqo.
• Ukukhohlela okumanzi okungapheliyo : Ukukhohlela okuvelisa i-mucus kunokuhlala ixesha elide.
• Indawo engaqhelekanga yamalungu (heterotaxia) : Njengoko bekutshiwo ngaphambili, amalungu asenokuba kwindawo engafanelekanga, amanye amalungu asenokungabikho, okanye asenokungakhuli kakuhle. I-Situs inversus yenye imeko enjalo.
• Ngamanye amaxesha isifo sentliziyo esizalwa naso .
• Ukulahlekelwa kukunyuka kwamandla emiphunga (i-atelectasis) .
• Ukukhula okufana ne-cyst kwizitho ezifana nezintso kunye ne-pancreas.
• Ukunqongophala kwee-antibody (ukunqongophala kwe-humoral (i-antibody)), okunokukhokelela kumngcipheko ophezulu wosulelo lwemiphunga kunye neesinus.

Iimpawu ze-PCD eziqhubekayo:

Ekuhambeni kwexesha, unokubona iimpawu ezifana nezi:

• Ukukhohlela okungapheliyo : Ukukhohlela okungapheliyo.
• I-sinusitis engapheliyo : Iingxaki ze-sinus ezihlala zikho.
• Usulelo lwendlebe : Usulelo lwendlebe oluhlala lukho, ukuphuma kolwelo ezindlebeni.
• Ukukhupha umhluzi kunye ne-phlegm egqithisileyo .
• Ukungazali (ingakumbi kumadoda).
• Iipolyps zempumlo .
• Ukuvela rhoqo kwe-pneumonia enzima .
• Usulelo oluqhelekileyo lokuphefumla oluphezulu .
• Ngamanye amaxesha kukho ukuqokelelana kwamanzi engqondweni (i-hydrocephalus).

Ifunyanwa njani i-primary ciliary dyskinesia (PCD)?

Enyanisweni, ukufumanisa oku kunzima kancinci. Akunakwenzeka ukutsho ngokuqinisekileyo ngovavanyo olunye nje ukuba yi-PCD. Oogqirha bafikelela kwisigqibo ngale nto emva kokwenza iimvavanyo ezahlukeneyo.

• Uvavanyo lwezonyango kunye nembali yezonyango: Okokuqala, ugqirha uza kukubuza ngeempawu zakho kunye nokuba kukho nabani na kusapho lwakho okhe waba neemeko ezifanayo.
• I-Cilia biopsy: Iqhekeza elincinci lesicubu lithathwa empumlweni okanye emiphungeni lize lihlolwe nge-microscope. Oku kusenza sibone imilo, ubukhulu, kunye nentshukumo ye-cilia.
• Uvavanyo lwemfuza:Olu vavanyo lujonga utshintsho lwezakhi zofuzo olunxulumene ne-PCD. Nangona kunjalo, kusenokwenzeka ukuba akunakwenzeka ukufumana olu tshintsho lwezakhi zofuzo kuye wonke umntu one-PCD.

Ukongeza koku, ezinye iimvavanyo zingenziwa ukuba kukho ukrokrelo lwe-PCD:

• Umlinganiselo we-nitric oxide ephuma empumlweni: Isixhobo esikhethekileyo silinganisa inqanaba legesi ebizwa ngokuba yi-nitric oxide emoyeni esiwukhuphayo. Abantu abane-PCD banamanqanaba aphantsi kakhulu ale gesi.
• Uvavanyo lokusebenza kwephaphu: Olu vavanyo lujonga ukuba imiphunga yakho isebenza kakuhle kangakanani na kwaye nokuba unengxaki yokuphefumla.
• I-video microscopy: Isampulu ye-cilia ithathwa ize ijongwe nge-microscope exhotyiswe ngekhamera yevidiyo enamandla aphezulu. Oku kuvumela ukuba i-cilia ibonwe ngesantya esicothayo, okuvumela ukufundwa ngokuchanekileyo komsebenzi wayo.

Iphathwa njani i-primary ciliary dyskinesia (PCD)?

Ngelishwa, akukho nyango lwe-PCD okwangoku . Nangona kunjalo, kukho unyango oluninzi olunokunceda ukulawula esi sifo, ukunciphisa iimpawu, nokwenza ubomi bube lula kancinci.

Injongo ephambili kukususa i-mucus kunye nolwelo oluqokelelana emiphungeni . Oku kwenziwa ngokwenza izinto ezinje:

• Ukucoca umoya: Umatshini okhethekileyo unceda ukukhulula nokususa i-mucus. Kukwakho neendlela ezikhethekileyo zokukhwehlela ezinceda ukucoca i-mucus.
• Unyango lomzimba esifubeni: Abanye abantu basebenzisa isixhobo esifana nevesti esichukumisa isifuba kancinci. Oku kunceda ukukhulula umhluzi kwaye kuncede ukuba uphume.
• Iityhubhu zendlebe: Ukuba unezifo zendlebe ezixhaphakileyo, iityhubhu ezincinci zingafakwa kwi-eardrum ukuze kukhutshwe ulwelo oluqokelelana kwindlebe ephakathi.

Ukongeza, amayeza anjengala anikwa ukulawula usulelo kunye nokudumba:

• Ii-antibiotics: Ezi zinikwa ukulawula usulelo lweentsholongwane emzimbeni. Kwezinye iimeko ezinzima, ii-antibiotics zinokufuneka zinikwe ngemithambo yegazi.
• I-Azithromycin: Eli liyeza elinceda ekunciphiseni ukudumba emiphungeni, kwaye ngamanye amaxesha lithathwa yonke imihla.
• IiBronchodilators: Amayeza afana ne-albuterol. La enza indlela yomoya ibe banzi kancinci, nto leyo eyenza kube lula ukuphefumla.
• IiCorticosteroids: Ezi zilawula ukusabela kweekhemikhali emzimbeni kwaye zinciphisa ukudumba.
• Izinto zokunciphisa i-mucus: La mayeza aphefumlwayo anceda ekunciphiseni i-mucus kwimibhobho yomoya kwaye enze kube lula ukuyikhupha.

Ngaba ndiza kufuna unyango olongezelelekileyo lwe-PCD?

Ngamanye amaxesha, njengoko kutshiwo apha ngasentla, ukuba amalungu omzimba akwiindawo ezingafanelekanga, kunokufuneka utyando ukuze alungiswe.Olu tyando lunokwenziwa emva nje kokuba umntwana ezelwe. Kwakhona, utyando olongezelelweyo lunokufuneka kamva ebomini ukuze kuthintelwe okanye kunyangwe iingxaki ezinokuvela.

Ngaba i-primary ciliary dyskinesia (PCD) ingathintelwa?

Ekubeni esi sisifo semfuza, akukho nto sinokuyenza ukuyithintela . Nangona kunjalo, ukuba ilungu losapho elisondeleyo line-PCD kwaye ucinga ngokuqalisa usapho, licebo elihle ukuqwalasela uvavanyo lwemfuza kunye neengcebiso zemfuza . Ezi nkonzo zinokukunceda ufumanise ukuba wena okanye umntwana wakho ninokuba nale meko.

Ingakanani iminyaka yokuphila yabantu abane-PCD?

Uninzi lwabantu luphila ubomi obude, ngokuqhelekileyo bade baluphale . Eyona nto ibalulekileyo kukufumana unyango olufanelekileyo nokuzinyamekela.

Ithini ingqikelelo yabantu abane-PCD?

Oku kuyahluka ngokwenene kumntu nomntu . Abanye abantu bagula ukususela ngomhla abazalwa ngawo kwaye banokuhlala benjalo ubomi babo bonke. Abanye banokuba sempilweni entle ngexesha labo lokuphumla baze bagule kakhulu ngamanye amaxesha. Kungoko ke, kubaluleke kakhulu ukuthetha nogqirha wakho ngemeko yakho kwaye ulandele iingcebiso zakhe.

Ziziphi iingxaki ezinokubakho ngenxa ye-PCD?

Ngenxa yokuba usulelo luhlala lusenzeka, lunokonakalisa izicwili zamalungu omzimba, lubangele amanxeba, kwaye lukhokelele kwiingxaki ezahlukeneyo. Umzekelo:

• Ukulahlekelwa kukuva .
• Ukwanda kunye nomonakalo kwimigudu yomoya (i-bronchiectasis) : Oku kunokubangela umonakalo ongakumbi kwimiphunga.
• Ukungaphumeleli kokuphefumla : Le meko inokwenzeka kwiimeko ezinzima kakhulu.

Zeziphi izinto ezibalulekileyo ekufuneka uzazi xa uphila ne-PCD?

I-PCD sisifo esingapheliyo. Ngoko ke, xa uphila naso, ungenza ubomi bakho bube lula kwaye wenze ezi zinto ukuze uhlale usempilweni:

• Ukuzilolonga: Xa usenza umthambo ophakathi, uphefumla nzulu. Oku kunceda ukukhulula i-mucus emiphungeni yakho kwaye kukuncede uphefumle lula. Kwakhona kwandisa amanqanaba akho amandla.
• Inkxaso ngokweemvakalelo: Ukuphila nesifo esingapheliyo esifana nesi kunokuba nzima ngokweemvakalelo ngamanye amaxesha. Kunokubakho imingeni. Ke ngoko, ukufumana inkxaso kwingcali yezempilo yengqondo, njengomcebisi, kunokunceda kakhulu ekunciphiseni uxinzelelo oluvayo.
• Ukuhlolwa rhoqo kwezonyango: Kuya kufuneka ubone ugqirha wakho rhoqo ukuze ubone ukuba unyango lwakho lusebenza kakuhle kangakanani na, ukuba iimpawu zakho ziya zisiba mandundu, okanye ukuba kukho iingxaki ezintsha ezikhulayo. Kusenokufuneka wenze uvavanyo lomsebenzi wamaphaphu rhoqo okanye ii-X-ray zesifuba.

Eyona nto ibalulekileyo kukungabi naxhala xa sele ufumanisa ukuba une-PCD, kodwa kukulandela imiyalelo kagqirha wakho ngokuchanekileyo kwaye uzinyamekele.

Umyalezo Wokuya Ekhaya

I-Primary Ciliary Dyskinesia (PCD) sisifo esingaqhelekanga, esibangelwa yimfuza esichaphazela kakhulu inkqubo yokuphefumla kunye neenkqubo zezitho zomzimba. Iimpawu zinokuba mandundu ngokuhamba kwexesha, kwaye iingxaki ezifana nokungaphumeleli kokuphefumla zinokubakho.

Nangona kunjalo, nangona kungekho nyango loku, kukho unyango olunokunceda ukulawula iimpawu nokunciphisa umngcipheko wosulelo . Izinto ezifana nokucoca umoya kunye namayeza zinokubonelela ngoncedo olukhulu. Kubalulekile ukufuna inkxaso yengqondo ukunceda ukunciphisa uxinzelelo lokuphila nesifo esingapheliyo esifana nesi. Awuwedwa, kwaye kukho oogqirha nabanye abanokukunceda.

` I-PCD, i-primary ciliary dyskinesia, i-cilia, inkqubo yokuphefumla, isifo semfuza, ukukhohlela okungapheliyo, ukubekwa kwamalungu omzimba, , isifo semfuza, ukukhohlela okungapheliyo, ukubekwa kwamalungu omzimba, isifo sokuphefumla