Wena okanye umntu omaziyo mhlawumbi unyangwa ngumhlaza. Ngexesha lonyango, ingakumbi i-chemotherapy, iiseli zomhlaza zitshatyalaliswa ngokukhawuleza. Nangona oku kuyinto entle, xa ezi seli zitshatyalaliswa, izinto ezingaphakathi kuzo, ingakumbi ikhemikhali ebizwa ngokuba yi-uric acid , ziqokelelana ngobuninzi egazini. Oku kwanda ngequbuliso kwe-uric acid akulunganga kwizintso zethu. Ngoko ke, kwiimeko ezinjalo, oogqirha basebenzisa iyeza elikhethekileyo elibizwa ngokuba yi-'Rasburicase'. Namhlanje, masithethe ngeli yeza ngokulula.
Yintoni le Rasburicase? Yintoni kanye kanye eyenzayo?
Ngamafutshane, iRasburicase (ರಾಸ್-ಬೀರೀ-ಕ್ಸ್) liyeza elilawula ubungakanani be-uric acid egazini lethu. Isetyenziswa kakhulu ukunciphisa nokuthintela ukunyuka ngequbuliso kwamanqanaba e-uric acid emzimbeni ngenxa yonyango lomhlaza.
Cinga ngemithambo yegazi yethu njengendlela. Xa iiseli zomhlaza zitshatyalalisiwe, i-uric acid idala ithrafikhi eninzi kule ndlela. Le thrafikhi inokuphazamisana nokusebenza kwesitho esibalulekileyo, izintso. Eli yeza elithi `Rasburicase` lisebenza njengepolisa lendlela, lisusa le thrafikhi ye-uric acid kwaye liyiguqule ibe yikhemikhali enokukhutshwa lula emzimbeni. Oku kuvumela ukuba unyango lomhlaza luqhubeke ngaphandle kokulimaza izintso.
Eli yeza lidla ngokuza njengolwelo (infusion) olufakwa emthanjeni. Oko kukuthi, lufakwa emzimbeni ngomlinganiselo omncinci, njenge-saline. Lunikwa esibhedlele okanye eklinikhi phantsi kweliso loogqirha kunye nabasebenzi babongikazi. I-'Elitek' ligama lophawu oludumileyo lwale yeza.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uthathe eli yeza
I-Rasburicase liyeza elinamandla kakhulu. Kungoko ke, kubaluleke kakhulu ukwazisa ugqirha wakho ngembali yakho epheleleyo yempilo ngaphambi kokuba uqale unyango. Kubaluleke kakhulu ukubaxelela ukuba unayo nayiphi na kwezi meko zilandelayo:
| Imeko yempilo okanye imbali | Kutheni kubalulekile? (Ingcaciso elula) |
|---|---|
| Ukunqongophala kwe-G6PD | Le yimeko yemfuza ebandakanya i-enzyme kwiiseli zegazi. Ukuba abantu abanale meko banikwa iRasburicase, iiseli ezibomvu zegazi zinokwaphuka zize zibangele i-anemia enzima. Ngoko ke oku kubaluleke kakhulu . |
| I-anemia okanye imbali yokunikela ngegazi | Ukuba sele une-anemia okanye ukhe watofelwa igazi ngaphambili, kubalulekile ukwazisa ugqirha wakho. |
| Iintlobo ngeentlobo zee-allergies (ii-Allergies) | Qiniseka ukuba uxelela ugqirha wakho ukuba une-allergies kwi-rasburicase, i-yeast, i-mannitol, amanye amayeza, ukutya, okanye iidayi. |
| Ukukhulelwa okanye ukuzama ukukhulelwa | Ukuba ukhulelwe okanye uceba ukukhulelwa, kubaluleke kakhulu ukuxelela ugqirha wakho. |
| Ukuncancisa | Ufanele ungancancisi xa usebenzisa eli yeza kwaye emva kweeveki ezimbini emva kokuliyeka. Ngoko ke, ukuba ungumama oncancisayo, xelela ugqirha wakho ngalo mbandela. |
Izinto ekufuneka uzilumkele xa usebenzisa eli yeza
Abasebenzi bezonyango baza kukubeka esweni ngononophelo olukhulu ngelixa unikwa eli yeza.
- Uvavanyo lwegazi: Ngexesha lonyango, kuya kufuneka uhlolwe igazi rhoqo ukujonga amanqanaba e-uric acid yakho, ukuba iyeza lisebenza kakuhle kangakanani na, kunye nokuba kukho naziphi na iziphumo ebezingalindelekanga. Oku kuqhelekile, ngoko ungakhathazeki.
- Amanye amayeza: Nika ugqirha wakho uluhlu olupheleleyo lwawo nawaphi na amanye amayeza, iivithamini, amayeza emifuno, kunye nezongezo ozithathayo. Amanye asenokusebenzisana nala mayeza.
- Kubantwana: Eli yeza ngamanye amaxesha linikwa abantwana abaneminyaka eyi-1 ubudala. Nangona kunjalo, kufuneka kulandelwe amanyathelo akhethekileyo okhuseleko. Ukuba unika umntwana wakho eli yeza, thetha nogqirha wezingane ngalo.
Ekubeni eli yeza linikwa esibhedlele phantsi kweliso elibukhali loogqirha nabahlengikazi, akufuneki ukhathazeke ngokugqithisileyo. Ukuba uziva ungakhululekanga nangayiphi na indlela, yazisa umongikazi okanye ugqirha ngokukhawuleza. Baza kuthatha amanyathelo afunekayo kuloo nto. Ukuba ukrokrela ukuba kukho enye into enokutyhefa, ungatsalela umnxeba iZiko loLwazi lweeTyhefu zeSizwe kwiSibhedlele sikaZwelonke saseColombo ukuze ufumane ingcebiso.
Zithini iziphumo ebezingalindelekanga zeRasburicase?
Njengayo nayiphi na iyeza, i-'Rasburicase' inokubangela iziphumo ebezingalindelekanga kwabanye abantu. Nangona kunjalo, ayinguye wonke umntu ozifumanayo. Eyona nto ibalulekileyo kukuxela naziphi na iimpawu ngoko nangoko.
| Uhlu lweziphumo ebezingalindelekanga | |
|---|---|
| Iziphumo ebezingalindelekanga ezinzulu ekufuneka uzixele kugqirha wakho okanye kumongikazi wakho ngoko nangoko | |
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe okanye ulwimi. |
| Ubunzima bokuphefumla | Ubunzima bokuphefumla, iintlungu zesifuba okanye ukuqina. |
| Iingxaki zokujikeleza kwegazi | Imilebe okanye iinzipho eziluhlaza okwesibhakabhaka, ukubetha kwentliziyo okukhawulezayo okanye okungahambelaniyo, ukuquleka, uxinzelelo lwegazi oluphantsi, ukutyheli kwamehlo okanye ulusu. |
| Ezinye iimpawu ezinzulu | Ukuxhuzula, ukudinwa kakhulu okanye ukudinwa, ukudideka. |
| Iziphumo ebezingalindelekanga ezingaqhelekanga, kodwa kufuneka zixelwe kugqirha ukuba ziyaqhubeka | |
| |
Olu luhlu alubandakanyi zonke iziphumo ebezingalindelekanga, ngoko ke ukuba ufumana into engaqhelekanga, ungoyiki ukuthetha nogqirha wakho ngayo.
Umyalezo Wokuya Ekhaya
- I-'Rasburicase' liyeza elikhethekileyo elinikwa esibhedlele ukunciphisa ubungakanani be-uric acid egazini eyandayo ngenxa yonyango lomhlaza.
- Ngaphambi kokuba uqale unyango, qiniseka ukuba uxelela ugqirha wakho malunga nokungabikho kwe-G6PD yakho, ii-allergies, kunye nazo zonke ezinye iimeko zempilo.
- Uvavanyo lwegazi rhoqo lubalulekile ngexesha lonyango.
- Yazisa ugqirha wakho okanye umongikazi wakho ngokukhawuleza ukuba ufumana naziphi na iimpawu ezinobungozi zokunganyamezelani komzimba, ezinje ngobunzima bokuphefumla, ukurhawuzelela kolusu, okanye ukudumba kobuso.
- Kuphephe ukuncancisa ngokupheleleyo xa usebenzisa eli yeza kwaye kwiiveki ezimbini emva kokuba uyekile.
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