Ngaba unikwe iRucaparib? Makhe sithethe ngale nto ngokweenkcukacha!

Kuqhelekile ukuba uzive uthwele umthwalo omkhulu xa ufumanisa ukuba unomhlaza. Kodwa xa ugqirha wakho ekuxelela ukuba uqale ukuthatha iyeza elibizwa ngokuba yi-'Rucaparib', kuqhelekile nokuba nemibuzo emininzi ngalo. Ngoko ke, namhlanje siza kuthetha ngezi pilisi zeRucaparib, ukuba liyintoni eli yeza, lisebenza njani, kunye noko kufuneka ukuqaphele, konke oku ngendlela elula kakhulu onokuyiqonda.

Yintoni kanye kanye le chiza ebizwa ngokuba yiRucaparib?

Ngamafutshane, iRucaparib liyeza elikhethekileyo elijolise kwiiproteni ezithile ngaphakathi kwiiseli zomhlaza kwaye lizithintele ekukhuleni kwazo . Ngamanye amazwi, lihlasela ngokukhethekileyo iiseli zomhlaza . Eli yeza lisetyenziswa kakhulu ukunyanga iintlobo ezithile zomhlaza wesibeleko kunye nomhlaza weprostate . Ngamanye amaxesha linokusetyenziswa kwezinye iintlobo zomhlaza, kwaye ugqirha wakho uya kukuxelela ngalo.

Xa uthenga eli yeza kwikhemesti, linokufumaneka phantsi kwegama lophawu elithi ``Rubraca``` . Nangona kunjalo, linokufumaneka phantsi kwamagama ahlukeneyo kumazwe ahlukeneyo nakwiinkampani ezahlukeneyo. Ngoko ke musa ukucinga nje ngegama, kufuneka ujonge ukuba ingaba iyeza olinikwe ngugqirha wakho liyiRucaparib na.

Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale eli yeza

Ngaphambi kokuba uqale ukusebenzisa iRucaparib, kubalulekile ukuxelela ugqirha wakho ngembali yakho yezonyango ukuze akwazi ukugqiba ukuba eli yeza likulungele na okanye ukuba kufuneka uthathe naziphi na izilumkiso ezikhethekileyo. Qiniseka ukuba uxelela ugqirha wakho malunga noku:

• Ukuba ukhe waba nezifo zegazi ngaphambili, umzekelo , i-myelodysplastic syndrome okanye i-leukemia .
• Ukuba unezinga eliphantsi leenxalenye zegazi , oko kuthetha ukuba uneeseli ezimhlophe zegazi, iiseli ezibomvu zegazi, okanye iiplatelets eziphantsi.
• Ukuba ukhe waba ne-allergy kule yeza, iRucaparib, okanye naliphi na elinye iyeza, ukutya, idayi, okanye isithinteli.
• Ukuba ukhulelwe okanye unethemba lokukhulelwa .
• Ukuba ungumama oncancisayo .

Akupheleli nje kwezi zinto, kodwa kubaluleke kakhulu ukuxelela ugqirha wakho ngazo naziphi na ezinye izifo onazo kunye namayeza owasebenzisayo (oko kuthetha ukuba kungekuphela nje lawo anikwe ngoogqirha, kodwa kwanalawo uwathengayo kwikhemesti, iivithamini, kwanamayeza emifuno).

Ngoko ke, ungayisebenzisa njani kanye kanye le yeza?

Eli yeza liza njengepilisi yokulisela ngomlomo . Kubalulekile ukulisela yonke imihla, ngexesha elinye naxeshikweni ugqirha wakho okanye ikhemisti ekuxelela lona. Landela imiyalelo ekwileyibhile yeyeza ngokuchanekileyo.

• IpilisiMusa ukuphula, ukutyumza, okanye ukuhlafuna. Ginya yonke ngamanzi.
• Oku kungasetyenziswa nokutya okanye ngaphandle kokutya . Nangona kunjalo, ukuba uziva isisu sibuhlungu, kungcono ukukuthatha nokutya.
• Ufanele uqhubeke nokusebenzisa eli yeza de ugqirha wakho akuxelele ukuba uyeke . Nokuba uzive ungcono, ungayeki ukulithatha ngequbuliso ngaphandle kwengcebiso kagqirha wakho. Ukwenza njalo kunokubangela ukuba imeko yakho ibe mandundu.

Ukuba unika abantwana eli yeza , kufuneka uthethe nogqirha wakho ngalo uze ufumane ingcebiso ekhethekileyo. Ngenxa yokuba imizimba yabantwana iyakhula, indlela abanikwa ngayo eli yeza inokutshintsha.

Khumbula, ukuba ucinga ukuba usele kakhulu eli yeza, ungoyiki, fowunela isibhedlele esikufutshane okanye kwiziko lolawulo lwetyhefu ngokukhawuleza. Oko kubaluleke kakhulu.

Eyona nto ibalulekileyo ekufuneka uyikhumbule: Eli yeza limiselwe wena kuphela . Musa ukulinika omnye umntu nangasiphi na isizathu, nokuba loo mntu uneempawu ezifanayo nezakho.

Wenza ntoni ukuba uphoswe yidosi yeyeza?

Ungakhathazeki, izinto zinokwenzeka. Ukuba uphoswe yidosi, yitsibe ngokupheleleyo idosi oyiphosileyo . Thatha idosi yakho elandelayo ngexesha eliqhelekileyo . Ungaze uthathe idosi ephindwe kabini ukuze ubuyisele idosi oyiphosileyo. Ukwenza njalo kunokunyusa umngcipheko weziphumo ebezingalindelekanga.

Ziziphi ezinye izinto ezinokusebenzisana nale mithi?

I-Rucaparib inokunxibelelana namanye amayeza nokutya okuthathayo. Oku kuthetha ukuba xa ithathwa kunye, inokuchaphazela indlela esebenza ngayo i-rucaparib okanye indlela esebenza ngayo amanye amayeza. Oku kunokunyusa umngcipheko weziphumo ebezingalindelekanga okanye kunciphise ukusebenza kakuhle kwamayeza. Ke ngoko, kubalulekile ukuxelela ugqirha wakho ngayo nayiphi na kwezi zilandelayo:

• Iziselo ezine- caffeine (ezifana neti, ikofu, ezinye iintlobo zetshokholethi, kunye nezinye iziselo ezibandayo).
• I-Digoxin (eli liyeza elidla ngokunikezelwa kwisifo sentliziyo).
• I-Midazolam (iyeza ngamanye amaxesha elinikwa ngaphambi kotyando okanye uvavanyo oluthile lokunciphisa ingqondo).
• I-Warfarin (eli liyeza elinikwa ukuthintela ukujiya kwegazi).

Olu luhlu luyimizekelo embalwa nje. Xelela ugqirha wakho ngayo yonke imithi oyithathayo (eyalelwe ngugqirha, ethengiswa ngaphandle kwemvume kagqirha, amayeza emifuno, iivithamini, kunye nezongezo) . Kwakhona, nyaniseka ngayo nayiphi na imithi oyitshayayo , oyisela utywala, okanye oyisebenzisayo . Ezi zinokuchaphazela nalo mayeza.

Zeziphi ezinye izinto ekufuneka uzilumkele ngakumbi xa usebenzisa eli yeza?

Xa usela eli yeza,Usenokuziva ungakhululekanga kwaye ugula kancinci kunesiqhelo. Yinto eqhelekileyo leyo. Oku kungenxa yokuba olu hlobo lwamayeza okulwa nomhlaza (usenokuba ukhe weva ngawo njenge -'chemotherapy' , nto leyo ayiyo) alunakuchaphazela iiseli zomhlaza kuphela, kodwa neeseli ezisempilweni emzimbeni wethu ukuya kwinqanaba elithile. Ke ngoko, ukuba ufumana naziphi na iziphumo ebezingalindelekanga, xelela ugqirha wakho ngazo. Nangona kunjalo, ungayeki ukuthatha amayeza kuba uzive ungakhululekanga ngaphandle kokuba ugqirha wakho ekuxelela ukuba uyeke .

• Uvavanyo lwegazi : Ugqirha wakho uza kukuxelela ukuba uhlolwe rhoqo inani legazi lakho (iiseli ezibomvu, iiseli ezimhlophe, iiplatelets, njl.njl.) ngelixa usebenzisa eli yeza. Kubaluleke kakhulu ukwenza olu vavanyo ngexesha kwaye ungaluyeki.
• Ukukhulelwa kunye nokuzala :
• Ukuba ungumfazi : Musa ukukhulelwa ngelixa usela eli yeza kwaye kangangeenyanga ezi-6 emva kokuyeka iyeza. Ukuba uzama ukukhulelwa, okanye ukuba ucinga ukuba ukhulelwe, kufuneka uxelele ugqirha wakho ngoko nangoko. Thetha nogqirha wakho malunga nolawulo lokuzala olufanelekileyo.
• Ukuba uyindoda : Musa ukuzama ukuba nguyise womntwana ngelixa usela eli yeza kwaye kangangeenyanga ezi-3 emva kokuyeka iyeza. Sebenzisa uhlobo olufanelekileyo lokuthintela ukuzalwa ngeli xesha. Eli yeza linokubangela ingozi enkulu kusana olungekazalwa. Buza ugqirha wakho ngolwazi oluthe kratya malunga noku.
• Ukuncancisa : Musa ukuncancisa umntwana wakho ngelixa usebenzisa eli yeza okanye iiveki ezimbini emva kokuba uyekile ukusebenzisa eli yeza.
• Ukunikela ngesidoda : Musa ukunikela ngesidoda ngelixa usebenzisa eli yeza okanye kangangeenyanga ezi-3 emva kokuyeka ukusebenzisa eli yeza.
• Umngcipheko wokosuleleka : Eli yeza lisenokunciphisa amasosha omzimba wakho kancinci . Oku kuthetha ukuba usenokuba sesichengeni sokufumana izifo. Ukuba ubonakalisa iimpawu ezinje ngomkhuhlane, impumlo egobhozayo, umphimbo obuhlungu, okanye ukubanda , musa ukuzenza unyango kwaye uxelele ugqirha wakho. Zama ukuhlala kude nabantu abagulayo kangangoko unako. Kukwangumbono olungileyo ukunxiba imaski yobuso xa usiya kwiindawo ezinabantu abaninzi.
• Iipilisi zokunciphisa iintlungu : Musa ukuthatha amayeza okunciphisa iintlungu anjenge -aspirin, i-acetaminophen, i-ibuprofen, i-naproxen, kunye ne-ketoprofen ngaphandle kwengcebiso kagqirha wakho. La mayeza angazifihla iimpawu ezifana nomkhuhlane, nto leyo eyenza kube nzima ukufumanisa usulelo.
• Xa uhlamba amazinyo akho kwaye ucoca umlomo wakho : Lumka xa usebenzisa ibrashi yamazinyo, i-flossing, okanye i-toothpicks. Oku kunokubangela ukopha okanye usulelo. Ukuba ufumana naluphi na unyango lwamazinyo, xelela ugqirha wamazinyo ukuba usela eli yeza.
• Umngcipheko womhlaza: Thetha nogqirha wakho malunga nomngcipheko wokufumana iintlobo ezithile zomhlaza (umzekelo, umhlaza wegazi) ngokuthatha eli yeza. Ngamanye amaxesha loo mngcipheko unokwanda kancinci. Nangona kunjalo, ugqirha wakho ukunika eli yeza kuba iingenelo zalo yeza zingaphezulu kweengozi.
• Uvakalelo lweLanga : Eli yeza lingenza ulusu lwakho lube buthathaka ngakumbi elangeni (photosensitivity) . Ngoko ke, nciphisa ukuvezwa kwakho elangeni kangangoko unako. Kuphephe ukuphuma ngexesha leeyure ezishushu kakhulu zemini, njenge-10 kusasa ukuya kwi-4 emva kwemini. Ukuba kufuneka uphume elangeni, nxiba impahla egquma ulusu lwakho (njengeehempe ezineemikhono emide kunye neebhulukhwe), umnqwazi, iiglasi zelanga, kwaye sebenzisa i-sunscreen ene-SPF engama-30 nangaphezulu . Musa ukusebenzisa izibane zelanga okanye iibhedi/ii-booths ze-tanning.

Ngoko ke, zithini iziphumo ebezingalindelekanga zale yeza?

Njengalo naliphi na iyeza, iipilisi zeRucaparib zinokubangela iziphumo ebezingalindelekanga kwabanye abantu. Nangona kunjalo, ayinguye wonke umntu ozifumanayo. Abanye abantu banokufumana iziphumo ebezingalindelekanga ezincinci kuphela. Eyona nto ibalulekileyo kukuxelela ugqirha wakho ukuba ubona into engaqhelekanga.

Iziphumo ebezingalindelekanga ekufuneka zixelwe kugqirha ngoko nangoko

Ukuba ufumana naziphi na kwezi mpawu, kufuneka uxelele ugqirha wakho ngoko nangoko :

• Iimpendulo ze-allergy : ukurhawuzelela kwesikhumba, ukurhawuzelela, ukurhawuzelela; ukudumba kobuso, imilebe, ulwimi, ubunzima bokuphefumla.
• Iimpawu zosulelo : umkhuhlane (ngaphezulu kwama-38 Celsius / 100.4 Fahrenheit), ukugodola, ukubila, ukukhohlela, umphimbo obuhlungu, iintlungu okanye ubunzima bokuchama, iintlungu zomzimba.
• Isitulo esinombala okhanyayo.
• Iimpawu zokulimala kwesibindi : Umchamo otyheli okanye omdaka omnyama; uzive udiniwe ngaphezu kwesiqhelo, umkhuhlane; ukuphelelwa ngumdla wokutya, iintlungu esiswini esingaphezulu ngasekunene; ukudinwa kakhulu; ukutyheli kwamehlo okanye ulusu (njenge-jaundice).
• Iimpawu zeeseli ezibomvu zegazi ezisezantsi (i-anemia) : Ukuphelelwa ngumphefumlo; ukutyhafa, ukuziva unesizungu, okanye ngathi uza kuwa; ukudinwa kakhulu, ulusu olukhanyayo, kunye nentlungu yesifuba.
• Ukugruzuka okanye ukopha okungaqhelekanga : Ukugruzuka, ukopha impumlo, ukopha iintsini xa uhlamba amazinyo, igazi elikwindle (elimnyama okanye elibomvu ngokumnyama).

Ukuba iyaqhubeka, okanye ukuba iyakukhathaza, kufuneka uxelele ugqirha wakho ngemiphumo emibi.

Ezi ziphumo bezingalindelekanga azibi kakhulu. Nangona kunjalo, ukuba ziyaqhubeka okanye zikukhathaza kakhulu , xelela ugqirha wakho:

• Ukuziva ngathi incasa yokutya itshintshile (`utshintsho kwincasa`).
• Ukuqhinwa.
• Urhudo.
• Ukulahlekelwa yintliziyo.
• Izilonda zomlomo.
• Isicaphucaphu.
• Ukuqhambuka kwesikhumba ( amabala amancinci abomvu, ngaphandle kweempawu ze-allergy ezikhankanyiweyo apha ngasentla).
• Intlungu yesisu.
• Ukuhlanza.
• Ukudinwa kakhulu (ngaphandle kweempawu ze-anemia ezikhankanyiweyo ngaphambili).

Olu luhlu alubandakanyi zonke iziphumo ebezingalindelekanga ezinokubakho. Ukuba ufumana nantoni na eyahlukileyo, thetha nogqirha wakho ngayo. Ungaxela ezi ziphumo ebezingalindelekanga kwi -FDA (i-U.S. Food and Drug Administration) ngokufowunela ku-1-800-FDA-1088.

Ndingazigcina njani ezi pilisi? Ndingazilahla njani ukuba kukho eziseleyo?

Eli yeza lifanele ligcinwe kude nabantwana nezilwanyana zasekhaya . Oko kubaluleke kakhulu.

• Gcina kubushushu begumbi (phakathi kwama-20 nama-25 degrees Celsius, okanye phakathi kwama-68 nama-77 degrees Fahrenheit). Musa ukuyibeka kwindawo eshushu kakhulu okanye efumileyo. Musa ukuyigcina kwiindawo ezifana negumbi lokuhlambela.
• Musa ukusebenzisa amayeza aphelelwe lixesha . Afanele alahlwe.

Indlela yokulahla amayeza angasetyenziswanga okanye aphelelwe lixesha:

• Eyona nto ingcono onokuyenza kukunika la mayeza "kwinkqubo yokubuyisela amayeza" . Ungabuza ikhemesti yakho, isibhedlele, okanye mhlawumbi iofisi yezempilo yasekuhlaleni malunga nezo ndawo.
• Ukuba akukho ndlela yokuyibuyisela, jonga ilebheli yamayeza okanye incwadana engaphakathi ukuze ubone ukuba ithi mayilahlwe enkunkuma okanye ilahlwe endlwini yangasese . Ukuba awuqinisekanga, buza ugqirha wakho okanye ikhemisti.
• Ukuba kukhuselekile ukulahla inkunkuma, susa iyeza ebhotileni okanye epakethini, ulixube kakuhle nenkunkuma yekati, ikofu esetyenzisiweyo, okanye umhlaba , ulifake kwibhegi okanye kwisikhongozeli esivalekayo, uze ulilahle kwinkunkuma. Oku kukuthintela ukuba lingabi yingxaki komnye umntu okanye kwisilwanyana.

Okokugqibela, eyona nto ibalulekileyo ekufuneka uyikhumbule

I-Rucaparib liyeza elibalulekileyo elinceda ekulweni nomhlaza. Xa usela eli yeza, kuyinto eqhelekileyo ukuba nemibuzo kunye neenkxalabo. Eyona nto ibalulekileyo kukuthetha ngokukhululekileyo nogqirha wakho ngayo yonke into . Ukuba uziva ungakhululekanga, ukuba ubona into entsha, nokuba incinci kangakanani na, xelela ugqirha wakho ngayo. Sela eli yeza kanye njengoko ekuxelela. Emva koko ungafumana okuninzi kolu nyango.

Eli nqaku liqulathe ulwazi olusisiseko kuphela malunga neyeza iRucaparib. Lisenokungabi nazo zonke iinkcukacha. Ukuba unemibuzo malunga neli yeza, thetha nogqirha wakho, ikhemisti, okanye omnye umboneleli wezempilo. Banokukunika ulwazi oluthe kratya. Khumbula ukuba awuwedwa, kwaye iqela lakho lezonyango lihlala likhona ukukunceda.

I- Rucaparib, amayeza omhlaza, umhlaza wesibeleko, umhlaza weprostate, iziphumo ebezingalindelekanga, unyango lomhlaza