Ngaba ugqirha ukunike uhlobo oluthile lwamayeza abizwa ngokuba yi-SNRI ngenxa yokudakumba kwakho okanye ixhala elingapheliyo? Mhlawumbi omnye wabahlobo bakho usebenzisa eli yeza. Usenokuba uzive usoyika kancinci xa usiva eli gama. Mhlawumbi unemibuzo emininzi engqondweni yakho efana nokuthi, "Lithini eli yeza? Ngaba lilungile emzimbeni?" Ke namhlanje, masithethe ngolu hlobo lwamayeza abizwa ngokuba yi-SNRI ngokulula, ngokungathi uthetha nomhlobo.
Ngamafutshane, zithini ezi SNRI?
Intsingiselo epheleleyo ye-SNRI yi -Serotonin kunye ne-Norepinephrine Reuptake Inhibitors . Kulungile, eli gama livakala liyinkimbinkimbi kancinci, akunjalo? Masilihlalutye size siliqonde ngokulula.
Ngaphakathi kwengqondo yethu, kukho izithunywa ezikhethekileyo zeekhemikhali ezilawula izinto ezininzi, kuquka iimvakalelo zethu, iingcinga, ukulala, kunye nomdla wokutya. Ezi sizibiza ngokuba "ziiNeurotransmitters." Njengomntu othumela imiyalezo, ezi zithunywa zithwala imiyalezo ukusuka kwenye indawo yengqondo ukuya kwenye.
Ezimbini kwezi zithunywa yi -serotonin kunye ne -norepinephrine .
- I-Serotonin ibaluleke kakhulu kwizinto ezifana neemvakalelo zethu, ukulala, kunye nokugaya ukutya. Xa amanqanaba e-serotonin ephezulu, siziva sonwabile kwaye sikhululekile.
- I-Norepinephrine isinceda sihlale sigxile, sinamandla, kwaye sisebenza.
Okuqhele ukwenzeka kukuba emva kokuba aba bathunywa bedlulise umyalezo wabo, iiseli zengqondo ziyabafunxa kwakhona. Oku kubizwa ngokuba yi-"Reuptake." Kanye njengokuba umntu othumelayo ebuyela eposini emva kokuhambisa ileta.
Nangona kunjalo, kubantu abaneemeko ezifana nokudakumba okanye ixhala, umsebenzi wezi zithunywa ze-serotonin kunye ne-norepinephrine unokuncipha kancinci engqondweni.
Kulapho ke amayeza e-SNRI angena khona. Oko kwenziwa ngala mayeza kukuthintela okwethutyana ukuphinda kuthathwe la mayeza. Kufana nokuxelela umntu othumelayo ukuba "alinde ixesha elide aze athumele imiyalezo embalwa." Emva koko la mayeza alungileyo (i-serotonin kunye ne-norepinephrine) ahlala engqondweni ixesha elide aze enze umsebenzi wawo omhle. Oku kuqala ukuphucula indlela esivakalelwa ngayo, kunciphise ixhala, kwaye konyuse amandla ethu.
Ngamafutshane, ii-SNRI luhlobo lwamayeza asinceda sizive ngcono ngokulinganisela amanqanaba eekhemikhali zendalo engqondweni yethu ezilawula "ulonwabo namandla."
Zeziphi iimeko ezisetyenziselwa amayeza e-SNRI?
Nangona la mayeza enikwa ikakhulu iingxaki zempilo yengqondo, oogqirha bawanika nezinye izifo zomzimba. Makhe sijonge ukuba zeziphi.
| Isigulo | Ingcaciso elula |
|---|---|
| Izihlandlo ezinconywayo kakhulu | |
| Ingxaki Enkulu Yokudakumba | Ukunciphisa iimpawu ezinje ngosizi olude, ukuphelelwa ngumdla kuyo nayiphi na into, kunye nokukruquka bubomi. |
| Ingxaki yokuxhalaba ngokubanzi | Ukulawula uloyiko, ixhala, kunye nokungazoli okuhlala kubuya engqondweni ngaphandle kwesizathu esithile. |
| Ingxaki Yokukhathazeka Kwentlalo | Ukunciphisa uloyiko olugqithisileyo kunye neentloni zokuthetha nokwenza phambi kwabanye. |
| Ingxaki yoXinzelelo | Ukuthintela ukuhlaselwa luloyiko ngequbuliso, okungalawulekiyo. |
| Intlungu Engapheliyo | Ukuphelisa iintlungu ezingapheliyo ezibangelwa zizifo ezifana ne-neuropathy enxulumene nesifo seswekile kunye ne-fibromyalgia. |
| Ezinye iimeko (Ukusetyenziswa ngaphandle kweleyibhile) | |
| Isifo Sokuxhalaba Okugqithisileyo (OCD) | Ukulawula ukwenzeka rhoqo kweengcinga ezingafunekiyo kunye nokuphindaphinda kwezinto ezithile ukuphendula kuzo. |
| Iimpawu zokuya exesheni | Ukulawula iimpawu ezinje ngobushushu obuvela xa umntu eyeka ukuya exesheni. |
| Iintloko ezibuhlungu | Njengonyango lokuthintela iintloko ezibuhlungu. |
Usenokuba uzibuza ukuba kuthetha ukuthini "ukusetyenziswa ngaphandle kweleyibhile". Oku kuthetha ukuba ugqirha, ngokusekelwe kulwazi lwakhe lwezonyango namava akhe, ucebisa iyeza lesinye isifo, ukongeza kwimeko ephambili evunyiweyo. Le yinto eyenziwa rhoqo.
Zeziphi iintlobo ze-SNRI ezixhaphakileyo eSri Lanka?
Kukho iintlobo ezahlukeneyo zamayeza e-SNRI. Ugqirha wakho uya kukhetha amayeza afanelekileyo kuwe ngokusekwe kwimeko yakho, ubudala, kunye nezinye iimeko zempilo.
- IVenlafaxine (njengegama lophawu i-Effexor®)
- I-Duloxetine (njengegama lophawu iCymbalta®)
- I-Desvenlafaxine (igama lophawu iPristiq®)
- UMilnacipran (igama lebrand Savella®)
- ILevomilnacipran (njengegama lophawu iFetzima®)
Iyeza olifumeneyo lisenokuba nenye kwezi zingasentla.
Zithini iziphumo ebezingalindelekanga ezinokubakho zokusebenzisa eli yeza?
Njengazo zonke amayeza, le inokuba nemiphumo emibi emincinci. Kodwa kubantu abaninzi, le miphumo ayibi mibi kangako. Idla ngokuvela kwiiveki zokuqala emva kokuthatha amayeza ize iphele xa umzimba wakho uqhelana namayeza.
| Imiphumela | Inkcazo |
|---|---|
| Iingxaki zenkqubo yokugaya ukutya | Isicaphucaphu, ukuhlanza, iintlungu zesisu, ukuqhina, okanye urhudo. |
| Isiyezi (vertigo) | Ukuba nesiyezi, ingakumbi xa umi okanye utshintsha indawo. |
| Umlomo owomileyo | Ukuziva ngathi kukho amathe emlonyeni. Oku kungalawulwa ngokusela amanzi amaninzi. |
| Ukubila okugqithisileyo | Ukubila kunokwanda, ingakumbi ebusuku. |
| Iingxaki zokulala | Abanye abantu banokuba nengxaki yokungalali, abanye banokuba nengxaki yokulala kakhulu. |
| Iingxaki zesondo | Izinto ezinje ngokuncipha komnqweno wesondo kunye nobunzima bokukhupha i-ejaculation zinokwenzeka. Musa ukuba namahloni okuthetha nogqirha wakho ngale nto. |
Eyona nto ibalulekileyo kukuba, ukuba ufumana isiphumo esifana nesi, kwaye kunzima ukusinyamezela, ungaze uyeke ukuthatha amayeza wedwa. Qiniseka ukuba uthetha nogqirha wakho ukuze akunike ingcebiso.
Iimeko zomngcipheko ezikhethekileyo ekufuneka ziqwalaselwe
Nangona ii-SNRI zihlala zingamayeza akhuselekileyo, kulungile ukuqaphela iingozi ezinkulu, nangona zinokwenzeka rhoqo.
1. Isifo seSerotonin
Le yeyona nto ibalulekileyo ekufuneka uyiqaphele. Xa ii-SNRI kunye nezinye iziyobisi ezichaphazela amanqanaba e-serotonin zithathwa kunye, amanqanaba e-serotonin engqondweni anokunyuka ngokungeyomfuneko. Le yingxamiseko enkulu yezonyango .
- Iimpawu: Ukudideka okungachazekiyo, ukubetha kwentliziyo ngokukhawuleza, umkhuhlane ophezulu, izihlunu eziqinileyo okanye ezibetha ngamandla, kunye nokubila kakhulu.
- Okufanele ukwenze: Ukuba wena okanye umntu omaziyo ngequbuliso ufumanisa ezi mpawu, bonana nogqirha ngoko nangoko okanye uye kwiSebe lezeMpilo eziNgxamisekileyo (ETU) lesibhedlele esikufutshane.
2. Iimpawu ezibakho xa uyeka ukusebenzisa amayeza (i-Antidepressant Discontinuation Syndrome)
Ukuba usela eli yeza ixesha elide uze uyeke ngequbuliso, umzimba wakho usenokungakhululeki ngenxa yempendulo yalo.
- Iimpawu:Ukudinwa, intloko ebuhlungu, isicaphucaphu, iintlungu zomzimba (njengaxa unomkhuhlane), kunye nokuxhalaba okukhulu.
- Ukuthintela: Ungaze uyeke ukuthatha amayeza ngaphandle kokubonisana nogqirha wakho. Ukuba kufuneka uyeke, ugqirha wakho uya kunciphisa umthamo kancinci kancinci kangangenyanga okanye ezimbini, avumele umzimba wakho ulungelelane, aze akubonise indlela yokuyeka ngokukhuselekileyo.
3. Iingcinga zokuzibulala
Le yingongoma ebucayi kakhulu, kodwa yinto ekufuneka ithethwe ngayo. Izifundo zifumanise ukuba kukho umngcipheko omncinci kakhulu wokwanda kweengcinga zokuzibulala, ingakumbi kubantu abancinci abangaphantsi kweminyaka engama-25 ubudala , kwiiveki zokuqala ezimbalwa zokusebenzisa eli yeza.
- Kubalulekile: Ukuba unale ngcinga, nceda ungabi buhlungu wedwa. Asikuko ukuba unetyala, isenokuba yimpembelelo engeyiyo yeyeza. Xelela ugqirha wakho ngoko nangoko. Xelela ilungu losapho okanye umhlobo omthembayo. Ukucela uncedo kuyakunika amandla.
Ezinye izinto ekufuneka uziqwalasele xa usebenzisa ii-SNRIs
Ukusela utywala
Kungcono ukungaseli utywala ngelixa usela amayeza okudakumba afana ne-SNRIs. Utywala bukwayinto ethomalalisa inkqubo yemithambo-luvo. Ngenxa yoko, bunokuphazamisa ukusebenza kakuhle kwamayeza. Utywala ngamanye amaxesha bunokwenza iimpawu zokudakumba zibe mandundu.
Amanye amayeza
Ukuba usebenzisa i-SNRI, xelela ugqirha wakho ngazo zonke ezinye iindlela ozisebenzisayo (izithomalalisi zentlungu, amayeza okukhwehlela, iivithamini, kwanemithi yesintu). Amanye amayeza anokuchasana ne-SNRI.
- Iipilisi zokunciphisa iintlungu ezifana nee-NSAID (umz. i-Ibuprofen, i-Diclofenac)
- Amayeza athintela ukujiya kwegazi (umz. i-Aspirin, i-Clopidogrel)
- IiTriptans ziziyobisi ezibangela i-migraine.
- Iimveliso zezityalo ezifana neSt. John's Wort
Ukukhulelwa kunye nokuncancisa
Ukuba uceba ukukhulelwa, sele ukhulelwe, okanye uncancisa, ngokuqinisekileyo kufuneka uthethe nogqirha wakho malunga nokusebenzisa eli yeza. Ezinye ii-SNRI zinokuchaphazela umntwana osesibelekweni. Kwakhona, ukuyeka iyeza ngequbuliso kunokuba yingozi kumama. Ugqirha wakho unokukunceda ukhethe ukuba loluphi ukhetho olukhuselekileyo kuwe nakumntwana wakho.
Kuthatha ixesha elingakanani ukuba iyeza lisebenze?
Lo ngumbuzo abantu abaninzi abawubuzayo. Ii-SNRI aziloyeza elisebenza ngoko nangoko njengePanadol. Kuthatha ixesha ukuba iinkqubo zeekhemikhali zobuchopho zilungelelane.
- Uninzi lwabantu luya kubona ukuphucuka (inkqubela) kwiimpawu kwiiveki ezi-4 ukuya kwezi-6 .
- Kungathatha phakathi kweeveki ezili-9 neli-12 (iinyanga ezi-2-3) ukuze abanye abantu bafumane uncedo olupheleleyo lwamayeza.
Ngoko ke, ungayeki ukuthatha amayeza kuba nje ungaziva mahluko ungako kwiiveki zokuqala ezimbalwa.Yiba nomonde. Ukuba awukaziva mahluko emva kwelo xesha, thetha nogqirha wakho kwakhona. Usenokukwazi ukulungisa umthamo okanye akutshintshele kwelinye iyeza.
Umyalezo Wokuya Ekhaya
- Ii-SNRI ngamayeza asebenzayo anceda ukulawula ukudakumba, ixhala, kunye nezinye iimeko zentlungu ngokulinganisela ukusebenza kwezithunywa zekhemikhali zendalo engqondweni yakho.
- Eli yeza alisebenzi ngoko nangoko. Kufuneka ube nomonde kwaye ulinde iiveki ezimbalwa ukuze ubone iziphumo.
- Njengakweminye imithi, kusenokubakho iziphumo ebezingalindelekanga ezincinci. Zihlala ziphela ngokuhamba kwexesha. Ukuba uneengxaki ezinganyamezelekiyo, xelela ugqirha wakho.
- Ungaze, nangasiphi na isizathu, uyeke ukuthatha eli yeza ngequbuliso ngaphandle kokubonisana nogqirha wakho. Ukwenza njalo kunokubangela iimpawu ezingathandekiyo.
- Kubalulekile ukwazisa ugqirha wakho ngazo zonke ezinye iziyobisi ozisebenzisayo, ukuba usela utywala, nokuba ukhulelwe.
- Ukuba unemibuzo, iinkxalabo, okanye amathandabuzo malunga namayeza akho, thetha ngawo ngokukhululekileyo nogqirha wakho. Nguye umcebisi wakho obalaseleyo nothembekileyo.
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