Kuqhelekile ukuba uzive usoyika kwaye unexhala xa wena okanye umntu omthandayo eqala unyango lomhlaza. Olo loyiko lunokwanda, ingakumbi xa usiva igama elithi 'chemotherapy'. Kodwa ungoyiki konke konke. Ukuze le nkqubo yonyango iphumelele, kufuneka kuqala sibe nolwazi olupheleleyo ngale mayeza. Emva koko singajongana nolu hambo kakuhle. Namhlanje sithetha ngelinye lamayeza alwa nomhlaza, iThioguanine (6-TG).
Luhlobo luni lweyeza iThioguanine (6-TG)?
Ngamafutshane, iThioguanine liyeza elilwa nomhlaza . Oogqirha balibiza ngokuba liyeza 'le-chemotherapy'. Umsebenzi walo ophambili kukuyeka ukukhula kweeseli zomhlaza ezahlulahlula ngokukhawuleza emzimbeni kwaye zitshabalalise.
Eli yeza lisetyenziselwa ngokukodwa ukunyanga iintlobo ezithile ze-leukemia , ezizii-cancer zeeseli zegazi. Ngamanye amaxesha, ugqirha wakho unokukunika eli yeza kwezinye iimeko. Ngoko ke ukuba unemibuzo malunga nokuba kutheni unikwe eli yeza, kungcono ubuze ugqirha wakho.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale amayeza
Ngaphambi kokuba uqale unyango lweThioguanine, kubaluleke kakhulu ukwazisa ugqirha wakho ngembali yakho epheleleyo yempilo. Kuba kufuneka silumke kakhulu xa sisebenzisa eli yeza kunye neemeko ezithile zempilo. Ukuba unayo nayiphi na kwezi zilandelayo, qiniseka ukuba usixelela ngalo.
| Imeko/inyani yempilo | Kutheni ufanele uxelele ugqirha? |
|---|---|
| Usulelo lwangoku (ingakumbi olo lubangelwa ziintsholongwane ezifana ne-chickenpox kunye ne-herpes) | Ngenxa yokuba eli yeza linciphisa amajoni omzimba, izifo ezikhoyo zinokuba mandundu. |
| Isifo sesibindi | Ngenxa yokuba eli yeza lisetyenzwa sisibindi, linokuba nemiphumo emibi kwisifo sesibindi. |
| Ukwehla kwenani leeseli zegazi (iiseli ezimhlophe zegazi, iiseli ezibomvu zegazi, iiplatelets) | I-Thioguanine inokunciphisa ngakumbi ukuveliswa kweeseli zegazi, nto leyo enokuba yingozi ukuba inani leeseli zegazi lakho sele liphantsi. |
| Ukunqongophala kwe-TPMT (ukunqongophala kwe-Thiopurine methyltransferase) | Le yimeko yemfuza. Abantu abangenayo le enzyme banokuba ne-Thioguanine eqokelelene emizimbeni yabo, nto leyo eyonyusa iziphumo ebezingalindelekanga. |
| Ii-aleji | Kubalulekile ukwazisa ugqirha wakho ukuba une-allergies kwiThioguanine okanye kwamanye amayeza okanye ukutya. |
| Ukuzama ukukhulelwa, ukukhulelwa, okanye ukuncancisa | Eli yeza linokubangela ingozi enkulu kumntwana ongekazalwa, ngoko ke kubalulekile ukuthetha ngalo. |
Ndingayisebenzisa njani le mithi?
Indlela yokusebenzisa eli yeza ilula kakhulu, kodwa ibaluleke kakhulu.
- Ginya ipilisi ngeglasi yamanzi , njengoko kuyalelwe kugqirha wakho.
- Sela amayeza akho yonke imihla, kanye njengoko ugqirha wakho ekuxelela, ngexesha oxelelwe ngalo. Musa ukulibazisa ixesha lokuya esibhedlele.
- Musa ukuyeka ukuthatha amayeza okanye ukutshintsha idosi nangasiphi na isizathu ngaphandle kwengcebiso kagqirha wakho.
- Ukuba unika abantwana eli yeza, thetha nogqirha wezingane ngalo uze ulandele imiyalelo yabo.
Ingqalelo: Ukuba ucinga ukuba uthathe amayeza angaphezu kwalawo amiselweyo, musa ukulibazisa. Fowunela iZiko loLwazi lweTyhefu leSizwe kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko okanye uye kwiSebe leNgxamiseko (ETU) lesibhedlele esikufutshane.
Yintoni omawuyenze ukuba uphoswe yidosi yeyeza?
Ukuba uphoswe yidosi, ungakhathazeki. Yitsibe idosi ephoswe yidosi uze uthathe idosi elandelayo ngexesha elicwangcisiweyo. Ungaze uthathe iidosi ezimbini ngaxeshanye.Oko kuthetha ukuba musa ukuthatha idosi ephindwe kabini ukuze uhlawulele elityelweyo. Ukuba uyahlanza emva kokusela iyeza, cela ingcebiso kugqirha wakho malunga nento omawuyenze ngokulandelayo.
Amanye amayeza anokusebenza kunye nale mayeza
Kubaluleke kakhulu ukuxelela ugqirha wakho malunga nawo onke amayeza owasebenzisayo, kuquka amayeza kagqirha, amayeza athengiswa ngaphandle kwemvume kagqirha, iivithamini, amayeza emifuno, kwanezongezo. Amanye amayeza anokusebenzisana neThioguanine aze onyuse iziphumo ebezingalindelekanga okanye atshintshe indlela esebenza ngayo.
Lumka ngakumbi ngamayeza alandelayo:
- I-Busulfan (elinye iyeza lokulwa nomhlaza)
- Amayeza athintela ukujiya kwegazi (umz. iWarfarin)
- Amayeza okunyusa inani leeseli zegazi (umz. i-filgrastim)
- Amachiza afana neMesalamine, iOlsalazine, iSulfasalazine, neBalsalazide
- Iigonyo zalo naluphi na uhlobo
Isilumkiso esikhethekileyo: Musa ukuthatha amayeza okunciphisa iintlungu athengiswa ngaphandle kwemvume kagqirha afana ne-aspirin, i-acetaminophen, kunye ne-ibuprofen ngaphandle kokubonisana nogqirha wakho. La mayeza angayithomalalisa iimpawu ezifana nomkhuhlane. Kubalulekile ukuqaphela umkhuhlane kwangethuba, njengoko unokuba luphawu lokuqala losulelo xa usebenzisa iThioguanine.
Izinto ekufuneka ziqwalaselwe xa usenza unyango
Ekubeni i-chemotherapy ichaphazela zombini iiseli zomhlaza kunye neeseli eziphilileyo, kuyinto eqhelekileyo ukuziva ungakhululekanga kwaye udiniwe. Nangona kunjalo, musa ukuyeka unyango de ugqirha wakho akuxelele ukuba wenze njalo ngenxa yezi ntlungu.
- Zikhusele kwiintsholongwane: Eli yeza liyawunciphisa umzimba wakho, ngoko ke unokuba sengozini yokugula. Ngoko ke, kuphephe ukuya kwiindawo ezinabantu abaninzi nokuba udibane nabantu abagulayo (abo banomkhuhlane okanye umkhuhlane) kangangoko unako. Ukuba ufumana iimpawu ezifana nomkhuhlane, umkhuhlane, umphimbo obuhlungu, okanye iintlungu zomzimba , musa ukuzinyanga kwaye uxelele ugqirha wakho ngoko nangoko.
- Lumka malunga nokopha: Umngcipheko wokopha unokwanda. Ngoko ke, hlamba amazinyo akho ngobunono. Musa ukusebenzisa iibhrashi eziqinileyo. Jonga ukuba akukho mivumbo okanye amabala amancinci abomvu eluswini. Ukuba ubona into efana naleyo, yazisa ugqirha wakho.
- Kuphephe ukukhulelwa: Oku kubaluleke kakhulu. Kuphephe ukukhulelwa ngokupheleleyo ngelixa usebenzisa eli yeza. Kwakhona, kuphephe ukuncancisa ngelixa usebenzisa eli yeza. Buza ugqirha wakho ukuba akunike ulwazi oluthe kratya ngalo mba.
Zeziphi iziphumo ebezingalindelekanga eziqhelekileyo?
Njengayo nayiphi na iyeza, iThioguanine inokubangela iziphumo ebezingalindelekanga. Kodwa ayinguye wonke umntu ozifumanayo. Ezinye zixhaphakile kakhulu, kwaye ezinye azifumaneki rhoqo. Into ebalulekileyo kukwazi ukuba zeziphi iziphumo ebezingalindelekanga kunye nento omawuyenze ukuba ziyavela.
| Iziphumo ebezingalindelekanga zeThioguanine (6-TG) | |
|---|---|
| 🚨 Iziphumo ebezingalindelekanga ezifuna unyango olukhawulezileyo | |
| Iimpawu ze-aleji | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe, ulwimi, ubunzima bokuphefumla. |
| Iimpawu zosulelo | Umkhuhlane, ukubanda, ukukhohlela, umphimbo obuhlungu, iintlungu xa uchama. |
| Iimpawu zokopha | Ukudumba kwesikhumba okungachazwanga, kukho amabala abomvu phantsi kwesikhumba, indle emnyama, kunye negazi kumchamo. |
| Iimpawu ze-anemia | Ukudinwa okungaqhelekanga, ukudinwa, isiyezi, amehlo aluhlaza okwesibhakabhaka. |
| Iingxaki zesibindi | Intlungu kwicala eliphezulu lasekunene lesisu, ukutyheli kwamehlo okanye ulusu (i-jaundice). |
| Ezinye iimpawu ezinzulu | Izilonda zomlomo, ukudumba kwamaqatha, iinyawo okanye isisu, ukunyuka kobunzima ngequbuliso. |
| 🙂 Iziphumo ebezingalindelekanga ekufuneka zixelwe kugqirha ukuba ziyaqhubeka | |
| Iingxaki zenkqubo yokugaya ukutya | Urhudo, ukungabi namdla wokutya, isicaphucaphu, ukuhlanza. |
Indlela yokugcina amayeza ngokufanelekileyo?
- Yigcine kwindawo ekhuselekileyo kude nabantwana.
- Gcina kwindawo eyomileyo kubushushu begumbi (phakathi kwe-15 kunye ne-25 degrees Celsius).
- Khusela ekufumeni. Ngoko ke gcina ibhotile yamayeza ivaliwe kakuhle.
- Lahla nayiphi na iyeza eliphelelwe lixesha.
Umyalezo Wokuya Ekhaya
- I-Thioguanine liyeza le-chemotherapy elisetyenziselwa ukunyanga umhlaza ofana ne-leukemia.
- Soloko usela amayeza akho kanye njengoko ugqirha wakho ekuyalele, ngexesha elifanelekileyo.
- Xelela ugqirha wakho ngazo zonke ezinye iindlela zonyango, iivithamini, kunye namayeza esintu owasebenzisayo.
- Ukuba ubona iimpawu zosulelo okanye ukopha, ezinje ngomkhuhlane, ukukrweleka, okanye ukukrweleka, yazisa ugqirha wakho ngoko nangoko.
- Kuphephe ngokupheleleyo ukukhulelwa nokuncancisa ngelixa usebenzisa eli yeza.
- Ungaze uyeke unyango okanye utshintshe umthamo ngaphandle kwengcebiso kagqirha.
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