Ngaba ugqirha wakho ukunike iyeza lokunciphisa i-cholesterol yakho? Usenokuba ulithatha. Ezi zibizwa ngokuba zii-statins. Zisinceda ekukhuseleni kwizifo ezinzulu ezifana nokuhlaselwa yintliziyo kunye nokubetha kwentliziyo. Kodwa ngamanye amaxesha la mayeza anokubangela ukungonwabi, ingakumbi iintlungu zemisipha. Ukuba kunjalo, eli nqaku liza kuba libaluleke kakhulu kuwe. Namhlanje siza kuthetha ngengxaki abantu abaninzi abanayo, ebizwa ngokuba yi-'statin tolerances'.
Okokuqala, masibone ukuba zithini ii-statins? Kutheni zisetyenziswa?
Ngamafutshane, ii-statins ludidi lwamayeza anikwa ngoogqirha ukunciphisa amanqanaba e-cholesterol "embi" kwisibindi nasegazini lethu. Usenokuba ukhe weva ngala magama: I-Atorvastatin, iRosuvastatin, iSimvastatin zezinye zezona statins zisetyenziswa kakhulu eSri Lanka.
Ngoku masiqonde kancinci nge-cholesterol. Khawucinge ukuba sineentlobo ezimbini ze-cholesterol emizimbeni yethu. Enye ifana nomhlobo olungileyo , enye ifana notshaba olubi .
- I-cholesterol elungileyo (i-HDL): Okukhona sinazo ezininzi emizimbeni yethu, kokukhona zisikhusela kwizifo ezifana nesifo sentliziyo kunye nesifo sohlangothi.
- I-cholesterol embi (LDL): Ezi ziintshaba zethu. Xa zisanda egazini, ziyahlala kwimithambo yegazi yethu, ziyivale kwaye zonyusa umngcipheko wokuhlaselwa sisifo sentliziyo kunye nestroke.
Amayeza e-statin asebenza ngokunciphisa amanqanaba e-cholesterol embi (LDL). Ngoko ke, la mayeza anceda abantu abasengozini yesifo sentliziyo ukuba baphile ubomi obusempilweni nobude.
Ngoko ke, yintoni 'ukunganyamezelani kwe-statin'?
Ukunganyamezelani ne-statin kuxa iziphumo ebezingalindelekanga ze-statin zingaphezulu kuneenzuzo. Oku kuthetha ukuba umzimba wakho awukwazi "ukulinyamezela" iyeza. Oku kungaba yi-allergy okanye enye impendulo engalunganga.
Xa oku kusenzeka, awusakwazi ukusebenzisa eli yeza ukunciphisa i-cholesterol yakho. Ngokuqhelekileyo, uphawu oluphambili lubuhlungu bemisipha, ukuthamba, okanye ubuthathaka .
Iimpawu eziqhelekileyo 'zokunganyamezelani kwe-Statin'
Ukuba sele uqalile ukusebenzisa ii-statins, hlala ulumkele ezi mpawu.
| Uphawu | Inkcazo |
|---|---|
| Intlungu yemisipha | Kuvakala ngathi uhlanza nje, izihlunu zakho zibuhlungu. |
| Umzimba ongenabomi | Ukuziva ubuthathaka kangangokuba awukwazi nokwenza imisebenzi eqhelekileyo. |
| Intlungu yomzimba | Iintlungu ezingapheliyo emalungeni nasezihlunwini. |
Okubaluleke kakhulu: Ukuba ufumana naziphi na kwezi mpawu, qiniseka ukuba uthetha nogqirha wakho ngaphambi kokuba uyeke ukusebenzisa amayeza. Ezi mpawu zihlala ziphela emva kokuba uyekile ukuwasebenzisa. Nangona kunjalo, ukuba uqhubeka ufumana ezi mpawu kwaye uqhubeka nokuwasebenzisa amayeza, unokuba sengozini yokonakala kwemisipha ngonaphakade.
Ziziphi izinto ezibangela umngcipheko wokuba ne-'Statin Intolerance'?
Abanye abantu banamathuba amaninzi okuba nale meko. Masihlule ezi zinto zinobungozi zibe ngamacandelo amabini. Ezinye asinakuzitshintsha, kodwa ezinye sinazo.
| Uhlobo lomngcipheko | Imizekelo |
|---|---|
| Izinto ezingaguqukiyo |
|
| Izinto ezilawulekayo |
|
Ugqirha uyixilonga njani ngokuchanekileyo le meko?
Xa ubona ugqirha wakho, uza kuqala akubuze ngeempawu zakho, naziphi na ezinye iindlela ozisebenzisayo, kunye nembali yempilo yosapho lwakho. Emva koko, banokwenza uvavanyo oluthile ukuze babone ukuba ngaba ii-statins zibangela iimpawu zakho okanye ukuba kukho enye imeko yezempilo.
- Uvavanyo lwegazi: Olu vavanyo lunceda ekuqinisekiseni ukuba akukho zi-enzymes zesibindi, ii-enzymes zemisipha (iCreatine Kinase), kunye nezinye iimeko zempilo.
- Uvavanyo lwezihlunu: Ukujonga ubuthathaka bezihlunu.
- Ezinye iimvavanyo: Kunokucetyiswa uvavanyo lwemfuza okanye i-muscle biopsy, kodwa ezi zihlala zenziwa rhoqo.
Ukuba une-'Statin Intolerance', zeziphi izisombululo onokuzifumana?
Khawucinge ukuba ugqirha ugqibe kwelokuba unale meko. Ungakhathazeki. Zininzi izisombululo zayo.
1. Ukutshintsha umthamo wamayeza akho: Ugqirha wakho anganciphisa umthamo wakho we-statin, okanye ayeke ukuthatha amayeza okwethutyana ukuze abone ukuba iimpawu zakho ziyaphucuka na. Ngamanye amaxesha, banokukutshintshela kuhlobo olwahlukileyo lwe-statin.
2. Amanye amayeza angengowe-statin: Ukuba ii-statin azinakusetyenziswa, kukho ezinye iintlobo zamayeza okwehlisa i-cholesterol.
- Izithinteli ze-ACL: Ezi zithintela ukuveliswa kwe-cholesterol embi (LDL) yisibindi.
- Izithinteli ze-PCSK9: Ezi zithintela iproteni ekhethekileyo emzimbeni wethu kwaye zinceda ukususa i-cholesterol embi (LDL) emzimbeni.
- IiFibrates: Ezi zinceda ekunciphiseni i-cholesterol embi (LDL) ngelixa zikwanyusa i-cholesterol elungileyo (HDL).
- Ii-Bile acid sequestrants: Ezi zithintela ukuphinda kufakwe i-cholesterol egazini.
3. Utshintsho kwindlela yokuphila: Oku kubaluleke kakhulu. Ukuba unayo okanye awunayo amayeza, ezi zinto zinokukunceda ukulawula amanqanaba akho e-cholesterol.
- Ukutya okunempilo: Yitya ioyile encinci, iswekile, netyuwa, kodwa yitya imifuno, iziqhamo kunye nemifuno emininzi.
- Ukuzilolonga: Ukwenza into efana nokuhamba okanye ukudada yonke imihla.
- Ukuyeka imikhwa emibi: ukuyeka ukutshaya nokusela utywala.
4. Izongezo: Kwezinye iimeko, ugqirha wakho unokucebisa ukuba uthathe izongezo ezifana ne-vitamin D okanye i-Coenzyme Q10 (CoQ10) ukunceda ukunciphisa iintlungu zemisipha. Nangona kunjalo, kubalulekile ukubonisana nogqirha wakho ngaphambi kokuba uqale ezi.
Umyalezo Wokuya Ekhaya
- Iistatins zibaluleke kakhulu ekunciphiseni i-cholesterol kunye nokukhusela kwizifo zentliziyo. Nangona kunjalo, zinokubangela iziphumo ebezingalindelekanga kwabanye abantu.
- Iintlungu zemisipha kunye nobuthathaka zezona mpawu ziphambili 'zokunganyamezelani kwe-Statin'. Ziqaphele ezi.
- Ukuba ufumana naziphi na kwezi mpawu, ungaze uyeke ukuzisela amayeza akho wedwa. Thetha nogqirha wakho kuqala.
- Nokuba 'unokunganyamezelani ne-statin', zikho ezinye iindlela zokulawula i-cholesterol yakho. Ngoko ke ungoyiki.
- Ukugcina indlela yokuphila esempilweni kubalulekile ekulawuleni i-cholesterol.
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