Masithi uye kugqirha ukuze ahlolwe rhoqo waza wafumana iziphumo zovavanyo lwakho lwegazi. Ugqirha, owayejonge ingxelo, wathi, "Iienzymes zesibindi sakho ziphezulu kancinci." Uyabona ukuba amaxabiso aphambi koonobumba ababini u-ALT kunye no-AST kwingxelo yakho angaphezulu kunesiqhelo. Kuqhelekile ukuziva usoyika kancinci xa oku kusenzeka. Kodwa ungoyiki. Namhlanje sithetha ngemeko ebizwa ngokuba yi-"Transaminitis", apho iienzymes zesibindi ziphezulu khona.
Ngamafutshane, yintoni i-Transaminitis?
I-'Transaminitis' ayisiyongxaki yezonyango imbi kakhulu. Oku kuthetha ukuba amanqanaba ee-enzyme ezithile ezibizwa ngokuba yi-'transaminases' egazini lakho anyuke kakhulu. Ii-enzyme ezimbini eziphambili yi -'Alanine Transaminase (ALT)` kunye ne-'Aspartate Transaminase (AST)` .
Cinga ngesibindi sakho njengomzi-mveliso omkhulu. Ezi enzymes ngabasebenzi abangaphakathi kwiiseli zaloo mzi-mveliso. Ngokwesiqhelo, aba basebenzi bangaphakathi kwifektri. Kodwa xa isibindi siphantsi koxinzelelo oluthile, umonakalo, okanye uxinzelelo, iiseli zesibindi zonakele kwaye abanye balaba basebenzi bavuza, oko kukuthi, egazini lethu. Ngengxelo yovavanyo lwegazi, silinganisa ubungakanani beeenzymes eziqokelelene egazini.
Uninzi lwexesha, le meko ifunyanwa ngengozi. Amanqanaba aphezulu e-ALT kunye ne-AST afunyanwa ngexesha lovavanyo lwegazi olwenziwe ngesinye isizathu. Nangona kunjalo, kwabanye abantu, xa beneempawu ezifana ne-jaundice, ukutyheli kwamehlo nolusu, okanye iintlungu kwicala eliphezulu lasekunene lesisu, ugqirha uyalela ezi mvavanyo, ngakumbi ukujonga ukusebenza kwesibindi.
Ngaba kuyingozi ukuba ezi enzymes zinyuswe?
Le ngxaki yinto abantu abaninzi abanayo. I-'Transaminitis' sisilumkiso sokuqala sokuba kukho umonakalo othile kwiiseli zesibindi. Kufana nesibane 'sokujonga injini' emotweni ezayo. Sikuxelela ukuba kukho into engalunganga emotweni, kwaye kufuneka uyijonge. Kwaye kunjalo nangoku.
Ubunzima boku buxhomekeke kwisizathu esiyintloko .
- Izizathu zexeshana: Ezi enzymes zinokunyuka okwethutyana xa kuselwa amayeza athile okanye ngenxa yosulelo lwexeshana. Xa unobangela uphelile, isibindi siyaphila kwaye amanqanaba eeenzyme abuyela kwisiqhelo.
- Izizathu zexesha elide: Nangona kunjalo, ukuba lo monakalo uyaqhubeka ngenxa yesifo esingapheliyo, unokuba mkhulu ngokuhamba kwexesha. Isibindi sethu sinamandla amangalisayo okuphiliswa, kodwa xa umonakalo uqhubeka, siyalahlekelwa ngaloo mandla kwaye sinokukhokelela kwimeko ebizwa ngokuba kukusilela kwesibindi.
Ngoko ke, eli ayilonani elinye kuphela. Lisisalathisi esibalulekileyo esikunika umbono ngempilo yakho iyonke.
Ziziphi izizathu ezinokubakho ze-transaminitis?
Zininzi izizathu zoku. Masizahlule zibe ziindidi ezimbini: ezona zizathu zixhaphakileyo kunye nezizathu ezingaqhelekanga kangako.
| Unobangela | Ingcaciso elula |
|---|---|
| Izizathu Eziqhelekileyo | |
| Isifo sesibindi esinamafutha | Okwangoku, sisifo esixhaphakileyo eSri Lanka. Ngokukodwa, sisifo esibizwa ngokuba yiMetabolic dysfunction-associated steatotic liver disease (MASLD) . Izinto ezibangela imetabolism ezifana nokutya okungekho sempilweni, ukutyeba, isifo seswekile, kunye ne-cholesterol ephezulu zinegalelo koku. |
| Ukusetyenziswa kotywala ngokugqithisileyo (iHepatitis ebangelwa butywala) | Ukusela utywala ngokugqithisileyo konakalisa isibindi ngokuthe ngqo, nto leyo enokubangela umonakalo wesibindi okwethutyana okanye ixesha elide. |
| Iintsholongwane ze-HIV (i-HIV) | Iintsholongwane ezifana ne-hepatitis A, B, C, D, kunye ne-E zinokubangela ukudumba kwesibindi. Oku kunokukhokelela kwi -hepatitis B kunye ne-C engapheliyo. |
| Iziphumo ezibangelwa ngamayeza (i-Toxic Hepatitis) | Amanye amayeza okudambisa iintlungu, amayeza okwehlisa i-cholesterol, amayeza esifo sephepha, kunye namanye amayeza anokuchaphazela isibindi. Ugqirha uhlala ekhangela oku. |
| Izinto Ezingaqhelekanga Ezibangela | |
| Ezinye izizathu | Iimeko ezifana neengxaki zenkqubo yomzimba yokuzikhusela (i-autoimmune hepatitis), izifo ezidluliselwa ngelifa (i-hemochromatosis, isifo sikaWilson), ukuhlaselwa yintliziyo, i-jaundice, isifo se-thyroid, kunye nomhlaza wesibindi ongaqhelekanga. |
Ngaba kuthetha into ekhethekileyo ukuba i-AST iphezulu kune-ALT?
Ngokwesiqhelo, xa isibindi sonakele, zombini ezi enzymes ziyanda kunye. I-enzyme i-ALT ixhomekeke ngakumbi kwisibindi. Oko kuthetha ukuba ifumaneka kakhulu kwisibindi. Nangona kunjalo, i-enzyme i-AST ikwafumaneka nakwimisipha yentliziyo, kwimisipha yamathambo, nakwezinye izicubu ukongeza kwisibindi.
Ngoko ke, ukuba ixabiso le-AST liphezulu kakhulu kunexabiso le-ALT , ugqirha uya kuqwalasela nezinye izinto. Umzekelo:
- Isifo sesibindi esibangelwa butywala: Kule meko, umlinganiselo we-AST/ALT uyanda.
- Isifo sokuqina kwesibindi: Le ndlela inokubonwa nangona isifo siqhubeka.
- Izizathu ezingaphaya kwesibindi: Amanqanaba e-AST anokunyuswa nakwiimeko ezifana ne-myocardial ischemia okanye umonakalo omkhulu wemisipha (rhabdomyolysis).
Okubaluleke kakhulu: La ngamacebiso nje. Musa ukuzama ukuzixilonga ngokwengxelo yakho. Oko kufanele kwenziwe ngugqirha wakho.
Ugqirha unyanga njani oku?
Okokuqala, khumbula ukuba akukho nyango ngqo lwe-'Transaminitis'. Kuba ayisosifo, kodwa luphawu. Ke ngoko, injongo ephambili kagqirha kukufumana unobangela wee-enzymes eziphezulu kunye nokunyanga loo nobangela.
Inkqubo yonyango idla ngokuba ngolu hlobo:
1. Imbali yezonyango: Ugqirha uza kukubuza ngendlela ophila ngayo (ukutya, umthambo, ukusebenzisa utywala), amayeza owaselayo, kunye nazo naziphi na iimeko zempilo kusapho lwakho.
2. Uvavanyo olongezelelweyo: Kuya kuthunyelwa olunye uvavanyo ukuqinisekisa unobangela.
- Phinda uvavanyo lwegazi.
- Uvavanyo lweentsholongwane zehepatitis B kunye ne-C.
- Iskeni ye-ultrasound yesisu.
- Ukuba kuyimfuneko, ezinye iimvavanyo zegazi ezikhethekileyo.
3. Unyango ngokwesizathu: Unyango lumiselwa emva kokuba imbangela ifunyenwe.
- Isibindi Esinamafutha: Utshintsho kwindlela yokuphila lubalulekile. Ukutya okunempilo , ukuzilolonga rhoqo , kunye nokunciphisa umzimba kubalulekile.
- Ukuba kungenxa yotywala: Isisombululo kuphela kukuyeka ukusebenzisa utywala ngokupheleleyo .
- Ukuba kungenxa yeyeza: Ugqirha uya kugqiba ukuba alitshintshe na iyeza okanye alinciphise na idosi.
- Ukuba kungenxa yentsholongwane: Unyango lwaloo ntsholongwane luya kuqala.
Kwiimeko ezininzi, xa unobangela oyintloko unyangwa ngokufanelekileyo, umonakalo kwisibindi uyayeka kwaye amanqanaba eeenzyme abuyela kwisiqhelo.
Umyalezo Wokuya Ekhaya
- I-Transaminitis (ii-enzymes zesibindi eziphakamileyo) luphawu olubonisa ukuba isibindi sakho siphantsi koxinzelelo oluthile. Musa ukoyika xa uyibona.
- Zininzi izizathu zoku. Isibindi esinamafutha, ukusetyenziswa kotywala, usulelo olubangelwa ziintsholongwane, kunye namayeza athile zizinto eziqhelekileyo.
- Unyango alujoliswanga kwinqanaba le-enzyme, kodwa kwimeko ebangela ukuba inyuke.
- Ukuba ubona amanqanaba aphezulu e-ALT kunye ne-AST kuvavanyo lwakho lwegazi, ungaze uyityeshele loo nto. Qiniseka ukuba ubona ugqirha wakho ukuze akunike iingcebiso ezifanelekileyo kunye nonyango.
- Kwiimeko ezininzi, ukwamkela indlela yokuphila enempilo (ukutya okunempilo, ukuzilolonga) kunceda kakhulu ekugcineni impilo yesibindi.
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