Xa wena okanye umntu kusapho lwakho efunyaniswa ukuba unomhlaza, kuyinto eqhelekileyo ukuba nomdla kwaye woyike kancinci ngonyango. Ingakumbi xa usiva ngamayeza amatsha, imibuzo efana nokuthi "Kuza kwenzeka ntoni ngale nto?" kunye nokuthi "Ngaba le nto iza kundisebenzela?" ifika engqondweni. Namhlanje siza kuthetha ngeyeza elitsha nelibaluleke kakhulu elisetyenziselwa ukunyanga umhlaza onjalo. Igama lalo yiDurvalumab. Masithethe ngalo ngokulula, ngendlela onokuyiqonda.
Know your body mass index (BMI) and weight classification
Yintoni iDurvalumab?
Ngamafutshane, iDurvalumab yi -antibody . Kodwa le ayisiyo-antibody eqhelekileyo. Le yi-antibody eyenziwe ngokukodwa kwilebhu. Yiyo loo nto siyibiza ngokuba yi-Monoclonal Antibody . Umsebenzi wayo ophambili kukunceda inkqubo yomzimba wethu yokuzikhusela, ukuyifundisa ukufumana nokuhlasela iiseli zomhlaza.
Khawucinge nje, sinomkhosi wokhuselo emzimbeni wethu (oko kukuthi, inkqubo yomzimba yokuzikhusela). Kodwa iiseli zomhlaza ziintshaba ezinobuqhetseba kakhulu. Ziyazifihla kwezi mikhosi zokhuselo kwaye zisasazeka emzimbeni ngokuzikhohlisa. Eli yeza elibizwa ngokuba yiDurvalumab lenza oku ngokubonisa ezo seli zomhlaza ezifihlakeleyo kumajoni ethu okhuselo. Kufana nokubaxelela oku, "Nanku apho utshaba lukhoyo, hambani niye kuhlasela." Ke ngoko, le ndlela yonyango ikwicandelo le- immunotherapy .
Eli yeza okwangoku lisetyenziswa kakhulu kumhlaza wemiphunga . Ngamanye amaxesha lingasetyenziswa kwezinye iintlobo zomhlaza. Oku kumiselwa ngugqirha wakho ngokusekelwe kwimeko yakho. Ungalifumana eli yeza phantsi kwegama lebrendi elithi IMFINZI.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale unyango
Ngaphambi kokuba uqalise eli yeza, kubaluleke kakhulu ukucacisa ngokucacileyo ezi zinto kugqirha wakho, njengoko olu lwazi luza kugqiba ukuba eli yeza lifanelekile na kuwe okanye ukuba ufuna unyango olukhethekileyo.
- Ukuba unezifo zokuzikhusela komzimba: Umzekelo, izifo ezifana nesifo sikaCrohn, i-ulcerative colitis, okanye i-lupus. Ezi ziimeko apho inkqubo yakho yokuzikhusela yomzimba ihlasela khona umzimba wakho.
- Ukuba ukhe watyandwa okanye uceba utyandwa i-stem cell: ingakumbi ukuba utyandwa i-allogeneic stem cell.
- Ukuba ukhe wafakelwa isitho sangasese ngaphambili: naliphi na ilungu elifana nezintso okanye isibindi.
- Ukuba ukhe wanyangwa ngemisebe esifubeni.
- Ukuba unezifo ezinxulumene nenkqubo yemithambo-luvo: Umzekelo, iimeko ezifana neMyasthenia Gravis okanye iGuillain-Barre syndrome.
- Ukuba une-allergy kwi-Durvalumab okanye naliphi na elinye iyeza, ukutya, okanye idayi.
- Ukuba ukhulelwe, uzama ukukhulelwa, okanye uncancisa, oku kubaluleke kakhulu .
Musa ukufihla naluphi na olu lwazi. Kubalulekile ukuba ugqirha azi konke oku ukuze ukhuseleke.
Ulinika njani eli yeza?
I-Durvalumab ayiloyeza onokulithatha uye nalo ekhaya. Liyeza elinikwa emzimbeni ngemithambo (ukufakwa kwe-infusion emthanjeni) . Kufana nokunika i-saline, kodwa inikwa kuphela esibhedlele okanye eklinikhi, phantsi kweliso lengcali yezonyango eqeqeshiweyo.
Ngaphambi kweseshoni nganye yonyango, uza kunikwa incwadana ekhethekileyo (iMedGuide) equlethe ulwazi malunga nale yeza. Yifunde ngononophelo rhoqo, kuba iqulethe ulwazi olubalulekileyo ekufuneka ulazi.
Kuthekani ukuba ndithatha amayeza amaninzi kakhulu?
Oku akunakwenzeka ukuba kwenzeke kuba kunikwa esibhedlele. Nangona kunjalo, ukuba ukrokrela ukuba uthathe amayeza amaninzi kakhulu, qhagamshelana ngokukhawuleza neZiko loLwazi lweeTyhefu kwiSibhedlele sikaZwelonke saseColombo okanye uye kwiSebe leNgxamiseko (ETU) lesibhedlele esikufutshane.
Kuthekani ukuba ndiphoswa yintlanganiso yamayeza?
Kubaluleke kakhulu ukuthatha amayeza akho ngexesha lonyango. Ukuba ngesizathu esithile awukwazi ukufika ngexesha, fowunela ugqirha wakho ngoko nangoko umxelele.
Izinto ekufuneka ziqwalaselwe ngexesha lonyango
- Ukungakhululeki okuqhelekileyo: Usenokuziva unesizungu okanye unesizungu xa usebenzisa eli yeza. Oku kuqhelekile. Nangona kunjalo, ngaphandle kokuba ugqirha wakho ekuxelele ukuba uyeke, qhubeka nonyango lwakho.
- Uvavanyo lwegazi: Kuyo yonke indlela onyangwa ngayo, kuya kufuneka uhlolwe igazi rhoqo ukuze ubone ukuba umzimba wakho usabela njani kunyango.
- Ukukhulelwa nokuncancisa (kubaluleke kakhulu): Kufuneka ukuphephe ukukhulelwa ngelixa usebenzisa eli yeza kwaye kangangeenyanga ezi-3 emva kokuyeka unyango. Eli yeza linokubangela ingozi enkulu kusana olungekazalwa. Ukuba uceba ukukhulelwa, thetha nogqirha wakho ngaphambi kokuba uqale unyango. Kufuneka ukuphephe nokuncancisa ngeli xesha.
Zithini iziphumo ebezingalindelekanga ezinokubakho?
Njengazo zonke iziyobisi, iDurvalumab inokubangela iziphumo ebezingalindelekanga. Nangona ingenguye wonke umntu ozifumanayo, ezinye zazo zinokuba yingozi, ngoko ke kubalulekile ukuba uzazi.
| Imiphumela | Ingcaciso |
|---|---|
| Iziphumo ebezingalindelekanga ekufuneka zixelwe kugqirha wakho ngoko nangoko | |
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe, ulwimi okanye umqala. |
| Intlungu yesisu kunye norhudo | Urhudo olunegazi okanye olumanzi, iintlungu eziqatha zesisu. |
| Ubunzima bokuphefumla | Ukukhohlela okomileyo, ubunzima bokuphefumla, ukuphefumla okuncinci. |
| Ukulimala kwesibindi | Intlungu esiswini esingaphezulu ngasekunene, ukungabi namdla wokutya, isicaphucaphu, ukutyheli kolusu okanye amehlo, umchamo otyheli/omdaka omnyama. |
| Iingxaki ngeendlala zehomoni | I-Hyperthyroidism: Ukubetha kwentliziyo ngokukhawuleza, ukwehla kobunzima, ukubila kakhulu, ukungcangcazela, ukungazinzi. I-Hypothyroidism: Ukudinwa kakhulu, ukungakwazi ukumelana nomkhuhlane, ukuqhina, ukutyeba, ulusu olomileyo. Umsebenzi ophantsi we-adrenal: isicaphucaphu, ukuhlanza, ukungabi namdla wokutya, isiyezi. |
| I-Pancreatitis | Intlungu ebuhlungu yesisu isasazeka emqolo, intlungu eba mandundu emva kokutya, umkhuhlane, isicaphucaphu, kunye nokuhlanza. |
| Ezinye iimpawu ezinzulu | Umkhuhlane, ukubanda, umphimbo obuhlungu (iimpawu zosulelo), ukubomvu kolusu, kuquka umlomo, amadyungudyungu, ulusu oluxobukayo, kunye ne-lymph nodes ezidumbileyo. |
| Iziphumo ebezingalindelekanga ezingaqhelekanga (kodwa kufuneka zixelwe kugqirha ukuba ziyaqhubeka) | |
| Ukudinwa | Ukudinwa ngaphandle kwesizathu esithile. |
| Ukulahleka kweenwele | Ukuncipha okanye ukulahleka kweenwele ngexesha lonyango. |
Olu luhlu alubandakanyi zonke iziphumo ebezingalindelekanga. Ukuba ufumana nantoni na engaqhelekanga engekho kolu luhlu, thetha nogqirha wakho ngayo.
Umyalezo Wokuya Ekhaya
- IDurvalumab liyeza elikhethekileyo elivuselela amajoni omzimba ukuba ahlasele iiseli zomhlaza.
- Xelela ugqirha wakho ngazo zonke iimeko zakho zempilo kunye nee-aleji zakho ngaphambi kokuba uqale unyango.
- Eli yeza linikwa kuphela ngemithambo esibhedlele. Asiloyeza elinokusiwa ekhaya.
- Kubaluleke kakhulu ukuphepha ukukhulelwa nokuncancisa ngexesha lonyango kunye neenyanga ezi-3 emva kokuyeka.
- Ukuba ufumana naziphi na iziphumo ebezingalindelekanga ezinje ngobunzima bokuphefumla, urhudo oluqatha, ukutyheli kolusu, okanye iingxaki zolusu eziqatha, funa ingcebiso kagqirha ngokukhawuleza.
- Thetha ngokukhululekileyo nogqirha onyangayo ngayo nayiphi na imibuzo okanye iinkxalabo onazo.
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