Cishe uke wezwa nge-collagen, akunjalo? Ake sithole okwengeziwe ngayo!

Kulezi zinsuku, uma sikhuluma ngobuhle nokugcina isikhumba sethu sihle, elinye lamagama aqhamuka ngokushesha yi-'collagen'. Kungenzeka ukuthi uke wabona okhilimu kanye nezithasiselo eziqukethe i-collagen, noma wezwa othile ekhuluma ngayo. Kodwa iyini ngempela i-collagen? Isebenzani emizimbeni yethu? Ingabe ibaluleke ngempela kithi? Ake sixoxe ngayo ngokuningiliziwe futhi namuhla.

Ngakho-ke, iyini le collagen?

Kalula nje, i-collagen iyiprotheni eningi kakhulu emizimbeni yethu. Cabanga nje, i-collagen yakha cishe u-30% weprotheni iyonke emizimbeni yethu. Iyisakhiwo esiyinhloko sezicubu ezixhumene njengesikhumba sethu, imisipha, amathambo, imisipha, kanye nemisipha. Itholakala futhi olwelwesini lwezitho zethu zangaphakathi, imithambo yegazi kanye namathumbu.

Cishe uyazi ukuthi amaprotheni akhiwa ama-amino acid. Ama-amino acid anegalelo elikhulu ekwakhekeni kwe-collagen yi -proline, i-glycine, kanye ne-hydroxyproline . Lawa ma-amino acid ahlangana ukuze akhe ama-fibril amancane amaprotheni, afana nesakhiwo se-triple helix. Kodwa-ke, ukuze le nqubo yokukhiqiza i-collagen iphumelele, umzimba wethu udinga futhi ukuthola izakhamzimba ezidingekayo njenge -vitamin C, i-zinc, ithusi, kanye ne-manganese . Ngaphandle kwalokhu, i-collagen ayinakwakheka kahle.

Yini eyenziwa yi-collagen emizimbeni yethu?

Umsebenzi oyinhloko we-Collagen ukunikeza isakhiwo, amandla, kanye nokusekela umzimba wethu wonke, njengoba nje kudingeka usimende ukwakha indlu.

Ake sixoxe ngeminye yemisebenzi ethile ye-collagen:

• Ungqimba oluphakathi lwesikhumba sethu, i-dermis, lusiza ekukhiqizeni uhlobo lweseli olubizwa ngokuthi ama-fibroblast . Lawa ma-fibroblast asiza ekukhuliseni amaseli amasha.
• I-Collagen idlala indima enkulu ekushintsheni amaseli esikhumba afile ngamaseli amasha.
• Ihlinzeka ngesembozo esivikelayo sezitho zethu zangaphakathi.
• I-Collagen inikeza isikhumba isakhiwo saso, amandla, kanye nokuguquguquka . Lokhu kubaluleke kakhulu ukuze isikhumba sihlale sithambile njengoba sasinjalo lapho sisesincane.
• Kuphinde kusize enkambisweni yokujiya kwegazi. Lokhu kusho ukuthi kuyasiza ekumiseni ukopha uma uthola inxeba.

Ingabe zikhona izinhlobo ze-collagen?

Yebo, kunezinhlobo eziningi ze-collagen. Kuze kube manje, ososayensi sebethole izinhlobo ezingaba ngu-28 ze-collagen. Lezi zihlukile ngendlela ama-molecule azo ahlanganiswa ngayo, izingxenye zamaseli ezinamathele kuzo, kanye nalapho i-collagen isetshenziswa khona emizimbeni yethu. Kodwa zonke lezi zindwangu ze-collagen zinesakhiwo se-triple helix okungenani esisodwa engikhulume ngaso ekuqaleni.

Manje ake sibheke izinhlobo ezinhlanu eziyinhloko ze-collagen ezibalulekile:

• Uhlobo I (Uhlobo Lokuqala): Yilokhu okwakha u-90% we-collagen emzimbeni wethu.Cabanga nje, kakhulu! Lolu hlobo lugcwele kakhulu. Lusetshenziswa kakhulu ukuhlinzeka ngesakhiwo esikhumbeni sethu, emathanjeni, emisipha kanye nasemisipha.
• Uhlobo II: Lolu hlobo lutholakala ku-cartilage enwebekayo. Lusiza ekuhlinzekeni ukwesekwa kwamalunga.
• Uhlobo lwesithathu (Uhlobo lwesithathu): Lokhu kungabonakala emisipheni, emithanjeni yegazi, nasezithweni zangaphakathi.
• Uhlobo IV (Uhlobo Lwesine): Lolu hlobo lutholakala ezingqimbeni ezahlukene zesikhumba sethu.
• Uhlobo V (Uhlobo Lwesihlanu): Lokhu kutholakala ku-cornea yamehlo ethu, ezinye izendlalelo zesikhumba, izinwele, kanye nezicubu ze-placental.

Kwenzekani ku-collagen njengoba sikhula?

Lena indaba edabukisayo. Njengoba siguga, imizimba yethu ikhiqiza i-collagen encane. Futhi, izinga lapho i-collagen esivele sinayo iphuka liyanda. Ngaphezu kwalokho, ikhwalithi ye-collagen esiyikhiqizayo njengoba siguga nayo iphansi kunangesikhathi sisebancane.

Ukukhiqizwa kwe-collagen kwehla kakhulu kwabesifazane, ikakhulukazi ngemva kokunqamuka kokuya esikhathini. Kuvamile ukuthi wonke umuntu abhekane nokwehla kokukhiqizwa kwe-collagen ngemva kweminyaka engu-60. Lesi ngesinye sezizathu ezenza kube nemibimbi yesikhumba kanye nobuhlungu bamalunga njengoba sikhula.

Ungakwazi yini ukubona ukuthi umzimba wakho ulahlekelwa yi-collagen?

Amazinga e-collagen awakwazi ukukalwa ngesampula yegazi. Kodwa-ke, kunezimpawu ezithile ezibonisa ukuthi amazinga akho e-collagen ayancipha. Uma ubona lokhu, kufanele ukhathazeke kancane:

• Isikhumba esishwabene, esigobile noma esigobile.
• Ukubonakala okugobile, okunezimbobo nxazonke kwamehlo nakwezinye izindawo zobuso.
• Ukuqaqamba kwemisipha, ubuthakathaka, kanye nobuhlungu bemisipha.
• Ukuqina kwemisipha kanye nemisipha, ukuncipha kokuguquguquka.
• Ubuhlungu bamalunga noma i-osteoarthritis ebangelwa ukuguguleka kwe-cartilage.
• Ubunzima bokunyakaza ngenxa yokulimala kwamalunga noma ukuqina kwawo, uzizwe sengathi ubambekile lapho uhamba.
• Izinkinga zesisu ezibangelwa ukuncipha kolwelwesi lwesimiso sokugaya ukudla.
• Izinkinga zokujikeleza kwegazi.

Ungacabangi ukuthi une-collagen ephansi ngoba nje unesinye noma ezimbili zalezi zimpawu, kodwa uma ziqhubeka, kuwumqondo omuhle ukufuna iseluleko sezokwelapha.

Yimiphi imikhuba yokuphila elimaza i-collagen?

Kunemikhuba ethile yansuku zonke esilimaza ngayo i-collagen yomzimba wethu ngokungazi. Ukugwema lokhu kunganciphisa ingozi yokulimala kwe-collagen. Nakhu ukuthi iyini:

• Ukubhema: Ukubhema kunciphisa ukukhiqizwa kwe-collagen. Akukhona lokho kuphela, kulimaza ne-collagen ekhona kanye nenye iphrotheni ebalulekile ebizwa ngokuthi i-elastin. Yingakho isikhumba sishwabana ngokushesha futhi amanxeba athatha isikhathi eside ukuphola. I-Nicotine ibangela ukuthi imithambo yegazi eseduze nobuso besikhumba inciphe. Lokhu kunciphisa inani lomoya-mpilo kanye nezakhamzimba ezidingwa yisikhumba.
• Ukudla ushukela ngokweqile kanye nama-carbohydrate acwengekile: Ushukela ubopha amaprotheni emzimbeni wethu,Kukhiwa imikhiqizo yokugcina ye-glycation ethuthukisiwe (ama-AGE), uhlobo lwe-molecule eyingozi. La ma-AGE alimaza amaprotheni aseduze, okwenza i-collagen ibe buthakathaka, yome, futhi iqhekeke. Lokhu kusho ukuthi kubaluleke kakhulu ukudla ukudla okunoshukela neziphuzo ngokulinganisela.
• Ukuchayeka ekukhanyeni kwe-ultraviolet: Ukuchayeka kakhulu elangeni kunciphisa ukukhiqizwa kwe-collagen futhi kubangela ukuthi i-collagen iqhekeke ngokushesha. Ukukhanya kwe-UV kuyimbangela eyinhloko yokuminyana. Ngakho-ke, gwema ukuchayeka kakhulu elangeni. Sebenzisa i-sunscreen (SPF 30 noma ngaphezulu) noma nini lapho uphuma ngaphandle.

Yiziphi izifo nezinye izimbangela ezilimaza i-collagen?

Ezinye izifo zingalimaza ne-collagen.

• Izifo ezithinta amasosha omzimba: Lezi yizimo lapho amasosha omzimba wethu ehlasela khona izicubu zethu. Izifo ezithinta amasosha omzimba ezifana ne -rheumatoid arthritis, i-lupus, i-dermatomyositis, kanye ne-scleroderma zaziwa ngokulimaza i-collagen.
• Ukuguquka kwezakhi zofuzo: Ezinye izimo zezakhi zofuzo zingabangela nokukhubazeka ekukhiqizweni kwe-collagen. I-Ehlers-Danlos syndrome kanye ne-osteogenesis imperfecta yizimo ezinjalo.
• Ukuguga: Njengoba kushiwo ngaphambili, amazinga e-collagen ayancipha ngokwemvelo njengoba sikhula.

Yini engenziwa ukulawula izimpawu zokuguga kanye nokulahlekelwa yi-collagen esikhumbeni?

Ukuze usize ekulawuleni imiphumela yokuguga kwesikhumba, gqoka isivikelo selanga nsuku zonke. Manje sesiyazi ukuthi ukuchayeka ekukhanyeni kwe-UV kulimaza i-collagen. Khetha umkhiqizo one-SPF (Sun Protection Factor) engama-30 noma ngaphezulu . Gqoka isigqoko esibanzi, izibuko zelanga ezivikela i-UV, kanye nezingubo ezilula, ezinemikhono emide uma ungaphandle. Ukuze uthole isivikelo esengeziwe, khetha izingubo ezinelebula le-ultraviolet protection factor. Gwema ukusebenzisa imibhede yokushiswa kwesikhumba.

Futhi, yidla ukudla okunomsoco. Ukudla okucebile ngemifino, ubhontshisi, okusanhlamvu okuphelele, amantongomane, izithelo, kanye nokudla kwasolwandle okulinganiselwe, inyama, izinkukhu, ubisi namaqanda kungumqondo omuhle.

I-collagen isetshenziswa kanjani emikhakheni yezokwelapha neyezimonyo?

Ngenxa yokuthi i-collagen ingaqhekeka, iguqulwe, futhi imuncwe umzimba, inokusetshenziswa okubanzi emikhakheni yezokwelapha kanye nezimonyo. I-Collagen esetshenziselwa izinjongo zokwelapha itholakala kubantu, ezinkomeni, ezingulubeni, noma ezimvini. Nazi ezinye izindlela zokusebenzisa:

• Izinto zokugcwalisa isikhumba:Imijovo ye-Collagen isetshenziselwa ukugcwalisa izinto ezifana nemigodi engajulile, imibimbi, kanye nemigqa esikhumbeni.
• Ukubopha amanxeba: I-Collagen isiza amanxeba ukuba aphole ngokudonsela amangqamuzana esikhumba amasha kuwo.
• I-Periodontics: I-Collagen isebenza njengesithiyo sokuvimbela izicubu zezinsini ezikhula ngokushesha ukuthi zingangeni enxebeni lezinyo, okunikeza amangqamuzana ezinyo isikhathi sokukhula kabusha.
• Izitho zokufakelwa zemithambo yegazi: Izitho zokufakelwa zezicubu ze-collagen ezivela kubanikeli ziye zasetshenziswa ukwakha kabusha imithambo yegazi, ukukhulisa kabusha imizwa yangaphandle, nokudala izitho zokufakelwa zemithambo yegazi.

Ingabe ukudla ukudla okucebile nge-collagen kwandisa amazinga e-collagen emzimbeni?

Lona umbuzo abantu abaningi abawubuzayo. Iqiniso liwukuthi, imizimba yethu ayikwazi ukumunca i-collagen yonke. Amaprotheni e-collagen esiwadlayo ahlukaniswa yimizimba yethu abe ama-amino acid. Ngakho-ke, ukudla ukudla okune-collagen eningi akukhulisi ngqo amazinga e-collagen emzimbeni.

Kodwa-ke, kunezinhlobo eziningi zokudla ezinikeza izithako ezisekela ukukhiqizwa kwe-collagen. Zingafakwa njengengxenye yokudla okunempilo. Lokhu kudla kuqukethe ama-amino acid i-Proline ne-Glycine engikushilo ekuqaleni. Futhi, le nqubo idinga izakhamzimba ezifana ne -Vitamin C, i-Zinc, ne-Copper . Nazi ezinye izinhlobo zokudla eziqukethe la ma-amino acid, amavithamini, namaminerali:

• I-Vitamin C: Amawolintshi, ama-strawberry, upelepele, i-broccoli, amahlumela aseBrussels, amazambane.
• I-Proline: Amakhowe, iklabishi, i-asparagus, amantongomane, ukolweni, inhlanzi, amaqanda amhlophe, inyama.
• I-Glycine: Inyama ebomvu, i-turkey, isikhumba senkukhu nengulube, amantongomane, i-granola.
• Ithusi: Isibindi, i-lobster, ama-oyster, amakhowe e-shiitake, amantongomane nembewu, imifino eluhlaza, i-tofu, ushokoledi omnyama.
• I-Zinc: Ama-oyster, inyama ebomvu, inkukhu, ingulube, ubhontshisi, uphizi, amantongomane, i-broccoli, imifino eluhlaza, okusanhlamvu okuphelele, imikhiqizo yobisi.

Ngakho-ke, nakuba kungasizi ukudla i-collagen ngqo, kubaluleke kakhulu ukudla ukudla okunomsoco okufana nalokhu okusiza ekwakheni i-collagen.

Ayini ama-Collagen Peptides?

Ama-peptide e-Collagen ayizingcezu ezincane ze-collagen yezilwane. Njengoba ngishilo ngaphambili, i-collagen ayimuncwa yonke. Kudingeka ihlukaniswe ibe ama-peptide amancane noma ama-amino acid. Izithasiselo ze-collagen zomlomo ziza ngesimo samaphilisi kanye nophuphu. Ngokuvamile ziqukethe ama-amino acid amabili noma amathathu. Lawa abizwa ngokuthi ama-collagen peptides noma i-hydrolyzed collagen.Ithengiswa kanjalo. Lawa ma-peptide e-collagen amuncwa ngomgudu wethu wokugaya ukudla.

Ucwaningo luthini ngempumelelo yezithako ze-collagen?

Lona umbuzo abantu abaningi abanawo. Eqinisweni, azikho izivivinyo ezanele ezilawulwa ngokungahleliwe (ama-RCT) ezithasiselo zokudla - indlela engcono kakhulu yokuhlola ukusebenza kahle kwemithi - ukuhlola ukusebenza kwayo. Izifundo ezimbalwa ezenziwe zithole ukuthi ama-peptide e-collagen angase asebenze kahle ngandlela thile ekuthuthukiseni umswakama wesikhumba kanye nokuqina kwawo. Kutholakale nokuthi asebenza kahle ngandlela thile ekunciphiseni ubuhlungu kanye nokuthuthukisa ukusebenza kwamalunga kubantu abane-osteoarthritis yamadolo.

Kodwa-ke, kunezinto ezimbalwa ezibalulekile okufanele uzazi ngesayensi ngemuva kwalezi zithako:

• I-US Food and Drug Administration (FDA) ayilawuli izithasiselo ze-collagen. Azidingi izivivinyo ezingaboni kabili, ezilawulwa yi-placebo, nezihleliwe ezidingekayo ukuze kuvunyelwe umuthi.
• Abakhiqizi bezithasiselo akudingeki bafakazele ukuthi imikhiqizo yabo iphephile noma iyasebenza ngaphambi kokuyifaka emakethe.
• Izifundo eziningi ngezithako zokudla zixhaswa yimboni yezithako zokudla uqobo, noma abalobi bezifundo banobudlelwano bezezimali nemboni yezithako zokudla. Lokhu kungaholela ekubandlululeni.
• Akukacaci ukuthi izithasiselo ze-collagen ziyakwenza yini ngempela lokho ezikukhuthazayo kulebula.

Okokugcina, kubalulekile ukukhumbula ukuthi kungakhathaliseki ukuthi uthola ama-peptide e-collagen ekudleni noma ezithasiselo, awukwazi ukuwaqondisa lapho uwafuna khona. Umzimba wakho usebenzisa lawo ma-peptide kunoma yini oyidingayo ngaleso sikhathi - kungakhathaliseki ukuthi ukwenza i-collagen noma enye iphrotheni.

Ngakho-ke, izinto ezibaluleke kakhulu okudingeka sizikhumbule (Umyalezo Wokuya Ekhaya)

Ngakho-ke, sikhulume kakhulu nge-collagen namuhla, akunjalo?

I-Collagen iyiprotheni ebaluleke kakhulu enikeza isakhiwo, amandla, kanye nokusekelwa emizimbeni yethu.

Kusenempikiswano ngezinzuzo zezithako ze-collagen. Umbuzo uwukuthi ingabe kukhona ubufakazi besayensi obuningi njengoba kubikwe kwabezindaba. Kudingeka ucwaningo olwengeziwe olushicilelwe ukuze kuboniswe izinzuzo zezempilo zangempela zezithako ze-collagen.

Okwamanje, ungasiza umzimba wakho ukuthi wenze i-collagen ngokwemvelo ngokudla ukudla okunempilo nokulinganiselayo . Ukudla okulinganiselayo kuhlanganisa izinto ezifana nenkukhu, inyama yenkomo, inhlanzi, imikhiqizo yobisi, amaqanda, ubhontshisi, imifino eluhlaza, eminye imifino, okusanhlamvu okuphelele, nezithelo ze-citrus.

Ukuze unciphise umonakalo ku-collagen yesikhumba sakho, ungabhemi, gwema intuthu ekhishwa ngabanye abantu, futhi ugqoke isivikelo selanga nsuku zonke. Lezi zinyathelo ezilula zizosiza kakhulu ekugcineni isikhumba sakho sibukeka sisesisha.

'i-collagen, impilo yesikhumba, ukuguga, amaprotheni, ubuhlungu bamalunga, ukudla, izithasiselo