Ingabe udokotela wakho ukunike umjovo okhethekile wokulawula isiqephu sokopha okungazelelwe kuwe noma ilungu lomndeni? Ungase udideke kancane ngegama. Kodwa ungakhathazeki. Sikhuluma ngalowo muthi namuhla. Ngokuvamile usetshenziselwa ukulawula ukopha esimweni esingavamile esibizwa ngokuthi i-Acquired Hemophilia A. Ake sixoxe ngakho kalula nangokucacile.
Iyini i-Acquired Hemophilia A?
Kalula nje, lokhu kuyinkinga ngenqubo yokujiya kwegazi emzimbeni wethu. Ngokuvamile, lapho silimala, igazi lethu liyajiya futhi liyeke ukopha. Lokhu kusizwa amaprotheni akhethekile egazini lethu, njenge -Factor VIII .
Kodwa-ke, ku-Acquired Hemophilia A, amasosha ethu omzimba aqala ngephutha ukuhlasela le phrotheni ebizwa ngokuthi i-Factor VIII. Siphinde sibize la ma-antibodies . Lokhu kunciphisa ikhono legazi lokujiya, futhi ngezinye izikhathi kuholela ekuphumeni kwegazi ngokweqile ngaphandle kwesizathu noma ngisho nokulimala okuncane. Lokhu akufani ne-hemophilia yokuzalwa, kodwa isimo esingase senzeke nganoma yisiphi isikhathi empilweni.
Ngakho-ke lo mjovo (i-OBIZUR) usebenza kanjani?
Manje usuyaqonda ukuthi inkinga ukuthi ama-antibodies ethu ahlasela i-Factor VIII yethu. Ngakho odokotela banikeza lo muthi okhethekile njengesixazululo salokhu.
Nakuba igama lalo muthi lide, lokho elikushoyo kubaluleke kakhulu:
- Isici Esilwa Nokuqhekeka Kwegazi: Lokhu kusho okuthile okulwa nesimo se-hemophilia, noma okukhuthaza ukujiya kwegazi.
- Ukulandelana Kwezingulube: Lokhu kuyinto ekhethekile. Igama elithi "Porcine" lisho okuthile okuhlobene nezingulube. Lo mjovo wenziwa ngendlela efana nokulandelana kwe-blood clotting factor yezingulube. Kungani kwenziwa ngaleyo ndlela? Ngoba, yize ama-antibodies emzimbeni wethu eqaphela futhi ehlasela i-human Factor VIII, awaqapheli isakhiwo esifana nale-pig factor. Ngakho-ke, angasiza inqubo yokuvala igazi ngaphandle kokuyihlasela.
- I-Recombinant: Lokhu kusho ukuthi umuthi awutholakali ngqo ezilwaneni, kodwa ukhiqizwa elabhorethri kusetshenziswa i-biotechnology (ubuchwepheshe be-DNA e-recombinant) ngendlela ehlanzekile nephephile.
Kalula nje, lokho okwenziwa yilo mjovo ukulawula ukopha ngokweqile ngokunikeza into umzimba wakho okudingeka uyijiye ngaphandle kokuthintwa ama-antibodies.
Izinto okudingeka uzitshele udokotela wakho ngaphambi kokuthatha lo muthi
Ngenxa yokuthi lo muthi ukhethekile, kubaluleke kakhulu ukwazisa udokotela wakho ngomlando wakho wezokwelapha ophelele ngaphambi kokuqala ukwelashwa.
| Okudingeka ukwazi | Kungani kunjalo? |
|---|---|
| Ukungezwani komzimba | Qiniseka ukuthi utshela udokotela wakho uma une-allergy kulo muthi, iphrotheni yengulube, iphrotheni ye-hamster (esetshenziswa ekwenziweni kwemithi ethile), noma yimuphi omunye umuthi, ukudla, noma udayi. |
| Ukukhulelwa noma ukuncelisa | Kubaluleke kakhulu ukwazisa udokotela wakho uma ukhulelwe, uzama ukukhulelwa, noma uncelisa. |
Uyisebenzisa kanjani le mithi?
Lona akuwona umuthi owugwinya njengephilisi elivamile. Lona umjovo womjovo ngemithambo yegazi . Lokwelashwa kuvame ukunikezwa esibhedlela noma emtholampilo ngudokotela noma umhlengikazi oqeqeshiwe. Lokhu kungenxa yokuthi udinga ukubhekwa ngokucophelela ngenkathi ukwelashwa kunikezwa.
Akuvamile kakhulu ukuthi ezinye iziguli ziyalwe ukuthi zithole lo muthi wokugoma ekhaya. Uma kunjalo, uzofundiswa ukuthi uwulungiselele kanjani futhi uwujove kahle. Ungalokothi uthathe okungaphezu kwalokho okuyalelwe udokotela noma uthathe umuthi ngaphambi kwesikhathi esibekiwe.
Yini okufanele uyenze uma umthamo wemithi ukhushuliwe?
Uma ucabanga ukuthi uthathe okungaphezu komthamo onqunyiwe, shayela ngokushesha i-National Poisons Information Centre e-Colombo National Hospital noma uye e-Emergency Treatment Unit (ETU) yesibhedlela esiseduze.
Kuthiwani uma ngiphuthelwa umthamo?
Kubaluleke kakhulu ukuthatha umthamo ngesikhathi ngesikhathi salokhu kwelashwa. Uma uphuthelwa yi-aphoyintimenti esibhedlela, shayela udokotela wakho ngokushesha ukuze uthole iseluleko. Uma uthatha umuthi ekhaya, thatha umthamo ophuthelwe ngokushesha nje lapho ukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, yeqa umthamo ophuthelwe bese uthatha umthamo olandelayo ngesikhathi esihleliwe. Ungathathi umthamo ophindwe kabili nganoma yisiphi isizathu.
Izinto okufanele uzicabangele ngesikhathi sokwelashwa
- Ukuhlolwa Kwegazi: Ngesikhathi uthatha lo muthi, udokotela wakho uzoyala ukuhlolwa kwegazi okuvamile ukuze ahlole ukuthi usebenza kahle yini, ukuthi igazi lakho lijiya kanjani, nokuthi umzimba wakho wenza yini ama-antibodies amasha ngokumelene nomuthi. Kubaluleke kakhulu ukungaweqi lo muthi.
- Ukuqapha kwezokwelapha: Ngesikhathi usesibhedlela, abasebenzi bezokwelapha bazokuqapha eduze. Bazohlala bebheka izimpawu zokopha kanye nokusabela kokungezwani komzimba.
- Umazisi Wezokwelapha: Uma une-hemophilia, kubaluleke kakhulu ukuthi uhlale uphethe ikhadi lomazisi wezokwelapha noma isongo/uchungechunge oluchaza isimo sakho, imithi oyiphuzayo, umthamo, kanye nezikhathi. Kungasiza ekusindiseni impilo yakho esimweni esiphuthumayo.
Yimiphi imiphumela emibi engaba khona?
Njenganoma yimuphi umuthi, lo muthi ungabangela imiphumela emibi, yize kungewona wonke umuntu oyitholayo. Uma uhlangabezana nanoma yiziphi izimpawu ezilandelayo, tshela udokotela wakho noma umhlengikazi ngokushesha.
| Uhlobo lomphumela ongemuhle | Izimpawu |
|---|---|
| Ukusabela Okubi Kakhulu Kokungezwani Nomzimba | Ukuqubuka kwesikhumba, ukulunywa noma ukuqubuka, ukuvuvukala kobuso, izindebe, ulimi noma umphimbo, ubunzima bokuphefumula. Lokhu kungaba kubi kakhulu futhi kufanele kubikwe ngokushesha. |
| Ukuthuthukiswa Kwezithibi | Uma ungakwazi ukulawula ukuphuma kwegazi ngisho nangemva kokuthatha umuthi, kusho ukuthi umzimba wakho kungenzeka ukuthi usuqalile ukwenza ama-antibodies ngokumelene nalo muthi. Tshela udokotela wakho ngalokhu. |
Uma uhlangabezana nanoma yiziphi ezinye izimpawu ezingavamile ezingashiwongo kulolu hlu, khuluma nodokotela wakho ngazo futhi.
Ukusebenzisana neminye imithi
Eminye imithi oyithathayo ingase ihlangane nalo muthi wokugomela, ikakhulukazi i-Factor VIIa.Kufanele uqaphele kakhulu uma usebenzisa lokhu neminye imithi yokunciphisa igazi, njenge:
Ngakho-ke, nikeza udokotela wakho uhlu oluphelele lwazo zonke izidakamizwa ozithathayo (imithi kadokotela, amavithamini, amakhambi, kanye nezithasiselo). Futhi, tshela udokotela wakho uma ubhema noma uphuza utshwala.
Umlayezo Wokuya Nawe Ekhaya
- Lo mjovo usetshenziselwa ukulawula ukopha ngokweqile esimweni esingavamile esibizwa ngokuthi i-Acquired Hemophilia A.
- Lokhu ukwelashwa okukhethekile okufakwa emthanjeni, okuvame ukwenziwa esibhedlela.
- Qiniseka ukuthi utshela udokotela wakho ngakho konke ukungezwani komzimba kwakho kanye nayo yonke eminye imithi oyithathayo.
- Uma uhlangabezana nezimpawu ezinkulu zokungezwani komzimba (ukuqubuka kwesikhumba, ukuvuvukala, ubunzima bokuphefumula), funa iseluleko sikadokotela ngokushesha.
- Ungayeki ukuhlolwa kwegazi kanye nokubona udokotela wakho.
- Lo muthi ungowakho wedwa. Ungalokothi uwuhlanganyele nabanye. Uma unemibuzo, khuluma nodokotela wakho.
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