Ingabe unenkinga ngamazinga aphansi e-calcium ngemva kokuhlinzwa? Kungaba yi-'Hungry Bone Syndrome'!

Njengoba kungenzeka wazi, ngemva kokuhlinzwa okuthile, ikakhulukazi lokho okususa i-thyroid gland entanyeni noma kuma-parathyroid glands aseduze, umzimba ungabhekana nezinhlobo ezimbalwa zokungakhululeki. Abanye abantu bangase bazizwe bekhathele ngendlela engakholeki, babe nobuhlungu bomzimba, noma bazizwe bedidekile kancane. Ngakho-ke uma wena noma othile omaziyo ebhekene nento efana nale, kungenzeka ukuthi kungenxa yesimo esizokhuluma ngaso namuhla esibizwa ngokuthi 'i-Hungry Bone Syndrome'. Leli gama lizwakala lingavamile, akunjalo? Ungase ucabange, "Kusho ukuthini ukuba namathambo alambile?" Ake sibheke ukuthi kuyini, ngamazwi alula.

Kuyini 'i-Hungry Bone Syndrome'?

Kalula nje, i-Hungry Bone Syndrome yisimo lapho amazinga e-calcium egazini lakho ehla khona ngokuzumayo kakhulu. Odokotela bakubiza ngokuthi "i-Hypocalcemia". Lesi simo sivame ukubonakala ngemva kokuhlinzwa kwezindlala ze-parathyroid. Ubuwazi ukuthi izindlala ze-parathyroid zibaluleke kakhulu ekulawuleni i-calcium emzimbeni wethu?

Abantu abanalesi 'sisifo samathambo esilambile' bangase bangabi namazinga aphansi e-calcium kuphela, kodwa ngezinye izikhathi babe namazinga aphansi e-magnesium (`(Hypomagnesemia)`) kanye ne-phosphorus (`(Hypophosphatemia)`) egazini labo. Lawa futhi amaminerali abalulekile adingwa yimizimba yethu.

Kodwa akukho okufanele ukhathazeke ngakho. I-'Hungry Bone Syndrome' yisimo esingelashwa futhi selapheke . Into ebaluleke kakhulu ukuyibona ngesikhathi bese uqala ukwelashwa.

Sivame kangakanani lesi simo?

Abacwaningi abanalo ngempela umbono oqondile wokuthi lesi 'sifo samathambo esilambile' sivame kangakanani, njengoba singahluka kuye ngomuntu.

Kodwa-ke, ezinye izifundo zibonise ukuthi phakathi kwabantu abangu-4 no-13 kwabayi-100 abaye bakhishwa i-parathyroid ngenxa yesimo esibizwa ngokuthi i-primary hyperparathyroidism baba nalesi simo. Futhi, eminye imibiko ithi ngemva kokuhlinzwa kwe-secondary and tertiary hyperparathyroidism, amathuba okuba lesi simo sikhule angaba ngu-20 kuya ku-70 kwabayi-100. Ngakho-ke, kubonakala sengathi lokhu kungaba yinto evamile kwezinye izimo.

Ziyini izimpawu ze-'Hungry Bone Syndrome'?

Izimpawu ze-'Hungry Bone Syndrome' zifana kakhulu nalezo ezibangelwa yi-calcium ephansi egazini (i-Hypocalcemia). Lezi zingaba zincane njengeqhubu elincane kwabanye abantu, zibe zimbi njengokudideka noma ukuxhuzula kwabanye. Nazi ezinye zezimpawu:

• Ukugingqa noma ukudonsa inyama: Umuzwa wokuthi inyama emilenzeni noma ezingalweni imane nje iyagingqa.
• Ubuthakathaka bemisipha: Ukuzizwa ungenampilo futhi ukhathele kakhulu ukwenza noma yini.
• Ubuhlungu bamathambo: Ukuzwa sengathi amathambo emzimbeni ayabuhlungu.
• Ukukhathala okukhulu: Ukukhathala okungapheli ngisho nangemva kokulala.
• Ukudideka: Ubunzima bokugxilisa ingqondo, ukungazi ukuthi benzeni.
• Izinkinga zememori: Ukukhohlwa izinto.
• Ukucasuka noma ukucasuka: Ukuthukuthela ngezinto ezincane, ukuzizwa ungakhululekile.
• Ukucindezeleka: Ukuzizwa udabukile futhi uphelelwe yithemba.
• Ukuba ndikindiki ezindebeni, olimini, ezinyaweni, kanye/noma ezinyaweni: Lezi zindawo zizwakala zindikindiki, noma njengezintuthwane ezigijimayo.
• Ubunzima bokuphefumula ngenxa yokuqina kwemisipha yomphimbo (`(Laryngospasm)`): Lokhu kuyingozi kancane, kwenza kube nzima ukuphefumula.
• Ukuqina kwemisipha nokudikiza (`(Tetany)`): Isimo lapho imisipha yomzimba iba lukhuni futhi idikize.
• Ukuquleka: Lokhu futhi kuyisibonakaliso esibi kakhulu.

Kanye nalezi zimpawu, njengoba kushiwo ngaphambili, amazinga aphansi e-magnesium ne-phosphorus egazini (`(Hypomagnesemia)` kanye `(Hypophosphatemia)`) angase avele. Izimpawu zalezi zimo zifana kakhulu nalezo ze-calcium ephansi. Zingabangela nezinkinga zemisipha, ukuxhuzula, kanye nokushaya kwenhliziyo okungajwayelekile (`(Arrhythmia)`).

I-Hungry bone syndrome ivame ukwenzeka zingakapheli amahora angu-18 ngemuva kokuhlinzwa kwe-parathyroid noma kwe-thyroid .

Kungani kwenzeka le 'Hungry Bone Syndrome'?

Kunezimbangela eziningana eziyinhloko ze-'Hungry Bone Syndrome':

• Ngemva kokuhlinzwa kwe-parathyroid (`(Parathyroidectomy)`) kwe-hyperparathyroidism eyinhloko noma yesibili.
• I-Thyrotoxicosis yisimo esenzeka ngemva kokususwa ngokuphelele kwe-thyroid.
• Uma umdlavuza we-prostate usakazekela emathanjeni (usuhlukaniswe).

Ukuze siqonde kahle ukuthi kungani lokhu kwenzeka, kubalulekile ukuqonda kancane ngendlela amazinga e-calcium alawulwa ngayo emizimbeni yethu.

Cabanga nje, ngemuva kwendlala yakho yegilo entanyeni yakho, kunezindlala ezine ezincane ezibizwa ngokuthi ama-parathyroid glands. Lezi zindlala zikhiqiza i-hormone ebizwa ngokuthi i-parathyroid hormone (PTH) . Umsebenzi oyinhloko wale hormone ye-PTH ukulawula izinga le-calcium egazini (hhayi emathanjeni, kodwa egazini). I-PTH iyasiza futhi ekulawuleni amazinga e-phosphorus (futhi eyiminerali) kanye ne-vitamin D (futhi eyi-hormone) egazini nasemathanjeni.

Ngakho-ke, uma umzimba wakho uzwa ukuthi izinga le-calcium egazini lakho liphansi, izindlala ze-parathyroid zikhipha i-hormone i-PTH. Le PTH iyahamba ikhiphe inani elincane le-calcium emathanjeni bese iyinezela egazini. Ngemuva kwalokho izinga le-calcium egazini libuyela esimweni esijwayelekile.

Manje, ake sithi othile unezindlala ze-parathyroid ezisebenza ngokweqile, bese ehlinzwa ukuze zisuswe. Okwenzekayo ukuthi amazinga e-PTH hormone ayephezulu kakhulu ngaphambili ehla ngokuzumayo. Ngezinye izikhathi, lapho kwenziwa ukuhlinzwa kwe-thyroid, uma izindlala ze-parathyroid eziseduze zonakele ngengozi, amazinga e-PTH nawo angase ehle.

Uma amazinga e-PTH ehla ngokuzumayo, inani le-calcium emathanjeni amadala elifakwa egazini (`(Resorption)`) liyancipha, futhi inani lokwakheka kwamathambo amasha (`(Bone Formation)`) liyakhula. Lokhu kubangela ukuthi amathambo "angabi naso" i-calcium. Yingakho lokhu kubizwa ngokuthi 'i-hungry bone syndrome'.

Yilokhu okwenzekayo lapho umdlavuza we-prostate usakazekela emathanjeni. Lapho, umsebenzi wamaseli akha amathambo (`(umsebenzi we-Osteoblastic)`) uyanda, ngakho-ke amathambo adinga i-calcium eyengeziwe.

Ubani osengozini enkulu yokuthola i-'Hungry Bone Syndrome'?

Abanye abantu banamathuba amaningi okuthola lesi simo. Ake sibheke ukuthi bangobani:

• Amazinga aphezulu kakhulu e-parathyroid hormone (PTH) egazini.
• Amazinga aphezulu e-alkaline phosphatase egazini.
• Amazinga e-calcium egazini avame ukuba phansi.
• Ukuba nokuntuleka kwe-vitamin D.
• Ukwenza ukuhlinzwa kwe-thyroid kanye ne-parathyroid ngesikhathi esisodwa.
• Amazinga e-urea nitrogen (BUN) egazini akhuphukile.
• Ukukhuluphala ngokweqile, okungukuthi, ukukhuluphala ngokweqile.
• Ukususwa ngokuhlinzwa kwendlala ye-parathyroid enkulu kunejwayelekile.
• Ukusabalala kwamangqamuzana omdlavuza emathanjeni (ama-Metastatic tumors amathambo).
• Ukuba khona kwezifo ezihlobene namathambo ezifana nezimila ezinsundu kanye ne-osteitis fibrosa cystica.

Abantu abanalezi zici eziyingozi banamathuba amaningi okuthola 'i-hungry bone syndrome'.

Odokotela bakuthola kanjani lokhu?

Udokotela uvame ukunquma kuqala ukuthi unesifo 'se-hungry bone syndrome' ngokwenza ukuhlolwa kwegazi le-calcium. Ngokuvamile, uma izinga le-calcium egazini lakho lingaphansi kuka-8.4 mg/dL izinsuku ezingaphezu kwezine, kubhekwa njengesici esiyingozi 'se-hungry bone syndrome'.

Akukhona lokho kuphela, kodwa udokotela wakho angase enze nezinye izivivinyo ezimbalwa ukuze abone ukuthi lesi simo sithinte yini ezinye izici zempilo yakho:

• Okunye ukuhlolwa kwegazi: Igazi lakho lingahlolwa amazinga e-magnesium, i-phosphorus, i-parathyroid hormone (PTH), kanye/noma i-vitamin D.
• I-EKG (i-Electrocardiogram): Lokhu kuhlolwa kulinganisa isigqi senhliziyo yakho ngokunamathisela ama-electrode esifubeni sakho. Lokhu kubalulekile ngoba i-calcium ephansi egazini (i-hypocalcemia) kanye 'ne-hungry bone syndrome' kungabangela ukushaya kwenhliziyo okungajwayelekile.
• Ukuhlolwa kwezithombe zamathambo: Lokhu kuhlolwa kungahlola izinkinga ngamathambo akho, njengokuphuka kwamathambo, ukukhubazeka, noma izimila.

Yiziphi izindlela zokwelapha i-'Hungry Bone Syndrome'?

Ungakhathazeki, kunezindlela zokwelapha ezinhle zalokhu. Umgomo oyinhloko wokwelashwa ukubuyisela izinga le-calcium egazini lakho ezingeni elinempilo. Ezimweni eziningi, uzothola lokhu kwelashwa ngenkathi usesibhedlela. Ukwelashwa kungafaka:

• Ukunikeza i-calcium ngemithambo yegazi (`(IV Calcium - Calcium Gluconate)`): Lokhu kusiza ukubuyisela amazinga e-calcium ngokushesha.
• Izithasiselo ze-Calcium eziphuzwa ngomlomo (i-Calcium Citrate noma i-Calcium Carbonate): Lezi zinikezwa ukugcina amazinga e-calcium.
• Izithasiselo zeVithamini D zomlomo: IVithamini D ibalulekile emzimbeni ukuze umunce i-calcium.
• Ukufakwa esikhundleni kwe-magnesium: Uma amazinga e-magnesium ephansi, nalokho kudinga ukulungiswa.

Odokotela bazohlola isimo sakho bese benquma ukwelashwa okufanele kakhulu kuwe.

Kuzothatha isikhathi esingakanani ukululama kulesi simo? Liyini ikusasa?

Izindaba ezinhle ukuthi lesi simo, 'i-Hungry Bone Syndrome', cishe selapheka ngokuphelele . Lokho kusho ukuthi isibikezelo sihle kakhulu.

Kodwa-ke, ngisho noma kwelashwa, isikhathi esithathwayo ukuze lesi simo siphele ngokuphelele singahluka. Abanye abantu baba ngcono ezinsukwini ezimbalwa, kanti abanye bangathatha izinyanga eziningana. Ezimweni ezingavamile kakhulu, kungahlala isikhathi esingafika onyakeni.

Okubaluleke kakhulu, uma kungelashwa, i-hypocalcemia enkulu ingaholela ezinkingeni ezisongela ukuphila njengokuxhuzula. Ngakho-ke, kubalulekile ukufuna ukwelashwa ngokushesha okukhulu uma kuvela izimpawu.

Ingabe i-'Hungry Bone Syndrome' ingavinjelwa?

Njengoba 'i-hungry bone syndrome' ingenzeka ngemva kokuhlinzwa kwe-parathyroid (`(Parathyroidectomy)`) noma ukuhlinzwa kwe-thyroid (`(Thyroidectomy)`), odokotela bazama ukuthatha izinyathelo zokuyivimbela ngisho nangaphambi kokuhlinzwa. Ake sibone ukuthi iyini:

• Ukuhlolwa kwangaphambi kokuhlinzwa: Ngaphambi kokuhlinzwa , udokotela wakho uzohlola ubuningi bamaminerali emathanjeni akho, amazinga e-calcium egazini, amazinga e-phosphate, amazinga e-PTH, kanye namazinga e-vitamin D. Lokhu kuhlolwa kungasiza udokotela wakho ukuthi anqume ukuthi usengozini yokuthola 'i-hungry bone syndrome'.
• Izindlela zokuvimbela:Uma usengozini enkulu yokuba ne-'hungry bone syndrome', udokotela wakho angase akuncome ukuthi uthathe izithasiselo noma imithi yokugcina amazinga akho e-vitamin D kanye ne-calcium ngaphambi kokuhlinzwa. Lokhu kungasiza ekunciphiseni amathuba kanye/noma ubukhali be-'hungry bone syndrome'.
• Ukuqapha ngemva kokuhlinzwa: Ngemva kokuhlinzwa, ithimba lesibhedlela lizohlola njalo amazinga akho e-calcium, i-phosphate, i-magnesium, kanye ne-PTH egazini. Lokhu kwenzelwa ukuthi uma uba ne-'hungry bone syndrome', itholakale kusenesikhathi futhi ukwelashwa kuqalwe ngokushesha.

Nokho, naphezu kwazo zonke lezi zinyathelo, ngezinye izikhathi 'i-hungry bone syndrome' ingavela. Abacwaningi abakaqiniseki ukuthi kungani lokhu kwenzeka.

Ngingayibona nini udokotela?

Uma uke wahlinzwa i-parathyroid noma i-thyroid futhi kamuva waba nezimpawu ze-calcium ephansi egazini (`(Hypocalcemia)`) esixoxe ngazo ngaphambili, njengokuqaqamba kwemisipha, umuzwa wobuthakathaka, izinguquko ekuqondeni (njengokudideka), kanye nokungazweli kwezindebe neminwe, kufanele nakanjani ubone udokotela ngokushesha ngangokunokwenzeka.** 'I-Hungry bone syndrome' kanye ne-`(Hypocalcemia)` zingavela ngemva kokuhlinzwa kwe-parathyroid kanye/noma i-thyroid, zingase ziphele ngemva kwezinsuku ezimbalwa, bese ziphinde zivele. Ngakho-ke, kubaluleke kakhulu ukunaka ngisho nophawu oluncane kakhulu.

'I-Hungry bone syndrome' yisimo esingase senzeke ngemva kokuhlinzwa ukuze kususwe i-parathyroid noma i-thyroid glands. Izindaba ezinhle ukuthi singelashwa futhi selapheke. Kodwa-ke, kungathatha isikhathi ukuthi silulame ngokugcwele. Njengoba ukwehla okukhulu kwamazinga e-calcium egazini kungaba yingozi empilweni yakho, kungcono ukubona udokotela ngokushesha nje lapho uzwa izimpawu.

Umyalezo oya nawo ekhaya

Ngakho-ke, kalula nje, i-'Hungry Bone Syndrome' yisimo esingaba khona ngemva kokuhlinzwa kwe-parathyroid noma i-thyroid gland. Okubalulekile ukuthi inani le-calcium egazini lomzimba lehla ngokuzumayo. Lokhu kungenxa yokuthi izinga le-parathyroid hormone (`(PTH)`) liyehla ngemva kokuhlinzwa, okubangela ukuba amathambo "afune" i-calcium.

Ungesabi ukuzwa lokhu, ngoba 'i-Hungry Bone Syndrome' yisimo esingelapheka futhi selapheke kahle kakhulu.

Into ebaluleke kakhulu ukuthi uma unezinye zalezi zimpawu (njengokudikiza kwemisipha, ukukhathala, ukungazweli), ungachithi isikhathi bese ubona udokotela ngokushesha okukhulu. Ngale ndlela, ungasibona lesi simo kusenesikhathi, uqale ukwelashwa okudingekayo ngokushesha, bese usiphulukisa ngaphambi kokuba sibe yinkinga enkulu. Khumbula, ukunakekela impilo yakho kusezandleni zakho.

'I-Hungry Bone Syndrome, I-Hungry Bone Syndrome, I-Calcium, I-Hypocalcemia, I-Parathyroid, Ukuhlinzwa Kwe-Thyroid, I-PTH