Uma wena noma othandekayo wakho ene-Cystic Fibrosis (CF), cishe uyazi kahle izinselele zokuphila nayo. Kodwa izindaba ezinhle ukuthi ngokuthuthuka kwesayensi yezokwelapha, manje sekukhona imithi emisha engakusiza ukubhekana nalesi simo. Namuhla, sizokhuluma ngesidakamizwa esisodwa esinjalo. Sibizwa ngokuthi i-Ivacaftor. Ungase usazi ngegama lomkhiqizo i-Kalydeco. Ake sibheke ngokushesha lesi sidakamizwa.
Kwenzekani ngempela ngalo muthi?
Kalula nje, i-Ivacaftor iyisidakamizwa esisetshenziselwa ukwelapha i-Cystic Fibrosis (CF) . Kodwa-ke, ayifaneleki kubo bonke abaguli abane-CF. Lo muthi usebenza kuphela kubantu abanezinguquko ezithile ezakhiweni zofuzo ezibangela i-CF. Udokotela wakho uzokwenza izivivinyo ezidingekayo ukuze anqume ukuthi lo muthi ukufanele yini.
I-Cystic Fibrosis yisifo esibangelwa izakhi zofuzo esonakalisa ukusebenza kweprotheyini emzimbeni wethu. Lokhu kubangela ukuthi uketshezi oluqinile nolunamathelayo luqoqeke ezithweni ezifana namaphaphu kanye ne-pancreas, okubangela izinkinga ezahlukahlukene. Umuthi i-Ivacaftor usebenza ngokubuyisela ukusebenza kweprotheyini engasebenzi kahle ngezinga elithile, unciphise uketshezi futhi uvumele ukuthi lususwe kalula emzimbeni.
Izinto okudingeka uzitshele udokotela wakho ngaphambi kokuqala imithi
Ngaphambi kokusebenzisa lo muthi, kubaluleke kakhulu ukunikeza udokotela wakho isithombe esicacile sempilo yakho iyonke. Qiniseka ukuthi ubatshela ngalezi zinto ikakhulukazi:
- Isifo sesibindi: Kubalulekile ukutshela udokotela wakho uma unesifo sesibindi. Lokhu kungenxa yokuthi lo muthi uguqulwa kakhulu yisibindi. Uma unezinkinga zesibindi, udokotela wakho kungadingeka alungise umthamo wakho.
- Isifo sezinso: Ngokufanayo, uma unezinkinga zezinso, sitshele nangalokho.
- Ukungezwani komzimba: Tshela udokotela wakho uma une-allergies ku-Ivacaftor noma kunoma yimuphi omunye umuthi, ukudla, noma udayi.
- Ukukhulelwa noma uhlela ukuba nomntwana: Uma ukhulelwe noma uzama ukukhulelwa, tshela udokotela wakho.
- Uma ungumama oncelisayo: Qiniseka ukuthi uyakusho lokhu uma uncelisa.
Kuphephile kuwe ukutshela udokotela ngaphandle kokufihla lolu lwazi. Ngakho ungakhohlwa ukumtshela noma ngabe kuyinto encane.
Ngiyisebenzisa kanjani ngempela le mithi?
Ukuze uthole okuningi ngomuthi, kubaluleke kakhulu ukuwusebenzisa ngendlela efanele.
Indlela yokuphuza umuthi
LomuthiKufanele nakanjani ithathwe kanye nokudla okunamafutha. Isibonelo, uma uthatha leli philisi nento efana neqanda, isinkwa esithosiwe ngoshizi, ucezu lwesinkwa olunebhotela lamakinati, noma i-omelet eyenziwe ngebhotela, umuthi uzomuncwa kangcono ngumzimba. Ungawuthathi esiswini esingenalutho.
Okubaluleke kakhulu: Ungawuthathi lo muthi nojusi we-grapefruit nganoma yisiphi isizathu. Ama-orange ase-Seville nawo awalungile. Lokhu kungathinta ukusebenza kahle komuthi.
Phuza umthamo onqunyiwe kuphela, uma unqunywe udokotela wakho. Gwema ukuthatha okwengeziwe. Ungayeki ukuthatha umuthi ngokuzumayo ngaphandle kweseluleko sikadokotela wakho.
Uma uyinika izingane
Lo muthi ngezinye izikhathi unikezwa izingane ezingaphezu kweminyaka engu-6. Kodwa-ke, khuluma nodokotela wezingane ngakho ngokucophelela bese ulandela imiyalelo yakhe.
Uma umthamo womuthi ukhuphukile (i-Overdose)
Uma ucabanga ukuthi uthathe umuthi omningi kakhulu, iya e-Emergency Treatment Unit (ETU) eseduze nawe ngokushesha . Noma shayela i-National Poisons Information Centre e-Colombo National Hospital ukuze uthole iseluleko.
Uma uphuthelwa umthamo wemithi
Uma uphuthelwa umthamo, thatha ngokushesha nje lapho ukhumbula. Kodwa-ke, uma kungaphansi kwamahora ayisithupha ngaphambi komthamo wakho olandelayo, yeqa umthamo ophuthelwe bese uthatha umthamo wakho olandelayo ngesikhathi esihleliwe. Ungalokothi uthathe umthamo ophindwe kabili.
Eminye imithi engase ihlangane ne-Ivacaftor
Kubaluleke kakhulu ukutshela udokotela wakho ngayo yonke imithi oyithathayo, okuhlanganisa amavithamini nemikhiqizo yamakhambi. Eminye imithi ingase ihlangane ne-Ivacaftor. Bheka leli thebula.
| Uhlobo lomuthi/into ethile | Izinga lokukhathazeka |
|---|---|
| Eminye imithi esetshenziselwa ukuxhuzula (isib. i-carbamazepine, i-phenobarbital, i-phenytoin) | Kunciphisa ukusebenza kahle kwe-Ivacaftor. |
| Ijusi le-Grapefruit nama-orange aseSeville | Kukhulisa ngokungadingekile ukuhlushwa kwesidakamizwa. |
| I-Rifampin, i-Rifabutin (imithi yokwelapha isifo sofuba) | Kunciphisa kakhulu ukusebenza kahle kwe-Ivacaftor. |
| I-St. John's Wort (umkhiqizo wezitshalo) | Kunciphisa ukusebenza kahle kwe-Ivacaftor. |
| Ama-antifungal (isb. i-ketoconazole, i-itraconazole, i-fluconazole) | Amazinga e-Ivacaftor angakhuphuka. |
| Amanye ama-antibiotic (isib. i-clarithromycin, i-erythromycin) | Amazinga e-Ivacaftor angakhuphuka. |
| I-Cyclosporine, i-Tacrolimus, i-Digoxin | I-Ivacaftor ingathinta ukusebenza kahle kwale mithi. |
Lolu hlu aluphelele, ngakho-ke kungcono ukutshela udokotela wakho ngakho konke okuthathayo.
Imiphumela emibi engaba khona yokuthatha umuthi
Njenganoma yimuphi umuthi, i-Ivacaftor ingabangela imiphumela emibi kwabanye abantu. Eminye yale miphumela iyingozi, kanti eminye imnene.
| Uma uhlangabezana nalezi zimpawu, tshela udokotela wakho ngokushesha. | |
|---|---|
| Izimpawu zokungezwani komzimba | Ukuqubuka kwesikhumba, ukulunywa, ukuvuvukala kobuso, izindebe noma ulimi. |
| Imiphumela esibindini | Umchamo omnyama, indle enombala okhanyayo, ukuphuzi kwamehlo noma isikhumba, ubuhlungu engxenyeni engenhla kwesokudla yesisu, ukulahlekelwa yisifiso sokudla. |
| Izinguquko zombono | Umbono ofiphele noma olunye ushintsho. |
| Okunye | Ukuzizwa ukhathele kakhulu, uzizwa sengathi unomkhuhlane. |
| Lokhu ngokuvamile akukubi kangako, kodwa uma kuqhubeka, tshela udokotela wakho. | |
| Uhlelo lokugaya ukudla | Ukungagayeki kahle kokudla, isicanucanu, uhudo. |
| Okunye | Ikhanda elibuhlungu , isiyezi , ubuhlungu bamalunga. |
Ngesikhathi ethatha lo muthi, udokotela wakho kungadingeka ahlole amehlo akho kanye namazinga ama-enzyme esibindi egazini lakho njalo. Lokhu kuvamile.
Ungayigcina kanjani imithi iphephile?
- Gcina kude nezingane.
- Gcina endaweni yokushisa yegumbi (phakathi kwama-degree Celsius angu-15-30).
- Lahla imithi ephelelwe yisikhathi ngaphandle kokuyisebenzisa.
Lo muthi unikezwe wena kuphela. Ungawubelani nanoma ubani nganoma yisiphi isizathu.
Umlayezo Wokuya Nawe Ekhaya
- I-Ivacaftor umuthi okhethekile onikezwa ukwelapha izinhlobo ezithile ze-cystic fibrosis.
- Lo muthi kufanele uphuzwe njalo nokudla okunamafutha.Yithathe. Ungalokothi uyithathe nejusi yamagilebhisi.
- Tshela udokotela wakho ngayo yonke eminye imithi oyithathayo kanye nazo zonke ezinye izifo zakho.
- Uma uhlangabezana nanoma yimiphi imiphumela emibi kakhulu, njengokuphuzi kwamehlo, umchamo omnyama, noma ukuqubuka kwesikhumba, tshela udokotela wakho ngokushesha.
- Lo muthi ungowakho wedwa. Ungawuniki omunye umuntu. Uma unemibuzo, khuluma nodokotela wakho njalo.
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