Uma wena noma othile emndenini wakho eqala ukwelashwa komdlavuza, kuvamile ukuzizwa ukhathazekile futhi unesifiso sokwazi ngemithi udokotela wakho ayinikezayo. Kubalulekile ukuba nolwazi oluphelele lapho uqala umuthi omusha. Ngakho-ke namuhla sizokhuluma ngomuthi owodwa onjalo wokulwa nomdlavuza, iLorlatinib. Ake sixoxe ngakho kalula, njengokungathi umngane ukuchazela wona.
Iyini i-Lorlatinib?
Kalula nje, i-lorlatinib akuyona imithi ejwayelekile ye-chemotherapy. Isebenza "njengokwelashwa okuqondiwe." Lokhu kusho ukuthi ihlose ngqo amaprotheni athile asiza amangqamuzana omdlavuza ukuba akhule. Ngokwenza kanjalo, ivimba amangqamuzana omdlavuza ekukhuleni.
Ivame ukusetshenziswa kakhulu ukwelapha isimo esibizwa ngokuthi "umdlavuza wamaphaphu ongewona oweseli elincane." Udokotela wakho angase akunike lo muthi nakwezinye izimo. Uma unemibuzo ngawo, buza udokotela wakho.
Izinto okufanele uzitshele udokotela wakho ngaphambi kokuqala imithi
Ngaphambi kokuba udokotela wakho akunike lo muthi, kubalulekile ukuqaphela ngokugcwele noma yiziphi ezinye izimo zezokwelapha ongase ube nazo. Lo muthi ungase uhlangane nalezo zimo. Ngakho-ke, uma unezinye zezimo ezilandelayo, qiniseka ukuthi utshela udokotela wakho.
- Isifo sikashukela (ushukela ophezulu egazini)
- Umfutho wegazi ophakeme
- I-cholesterol ephezulu
- Ukungalingani kwesigqi senhliziyo noma isifo senhliziyo
- Isifo sezinso
- Isifo samaphaphu noma izibazi zamaphaphu
- Noma yisiphi isifo sengqondo
- Izimo ezifana nokuquleka
- Imicabango yokuzilimaza, imicabango yokuzibulala, ukuzama ukwenza kanjalo, noma ukuba nelungu lomndeni elikwenzayo lokho
- Ukuzama ukukhulelwa noma ukukhulelwa njengamanje
- Ukuncelisa ingane
- Uke waba nokusabela kokungezwani komzimba ne-lorlatinib noma yimuphi omunye umuthi, ukudla, noma idayi ngaphambilini
Uyisebenzisa kanjani kahle le mithi?
Ukulandela imiyalelo eqondile yokusebenzisa lo muthi kubaluleke kakhulu emiphumeleni.
- Thatha leli philisi njengoba nje udokotela wakho ekuyalele, ngesikhathi esifanayo nsuku zonke .
- Ungalichobozi, ulichoboze, noma ulihlafune iphilisi. Ligwinye lonke ngamanzi.
- Ungayithatha ngaphambi noma ngemva kokudla, kodwa uma uzwa ubuhlungu besisu, kungcono ukuyithatha kanye nokudla.
- Qhubeka usebenzisa lokhu kwelashwa kuze kube yilapho udokotela wakho ekutshela ukuthi uyeke.
- Kubaluleke kakhulu:Gwema ukuphuza ijusi yamagilebhisi ngokuphelele ngenkathi uthatha lo muthi.
Kuthiwani uma umthamo uphezulu kakhulu? (Umthamo oweqile)
Uma ucabanga ukuthi uthathe umuthi omningi kakhulu, iya eMnyangweni Wezimo Eziphuthumayo (ETU) oseduze nawe ngokushesha . Noma shayela i-National Poisons Information Centre e-Colombo National Hospital ukuze uthole iseluleko.
Yini okufanele uyenze uma uphuthelwa umthamo wemithi?
Uma ukhohlwa ukuthatha umthamo, thatha ngokushesha nje lapho ukhumbula. Kodwa-ke, uma kungaphansi kwamahora ama-4 ngaphambi komthamo wakho olandelayo, yeqa umthamo ongawutholanga. Vele uthathe umthamo olandelayo ngesikhathi esihleliwe. Ungalokothi uthathe umthamo ophindwe kabili .
Eminye imithi engase ihlangane nalo muthi
I-Lorlatinib umuthi onamandla amakhulu okuxhumana neminye imithi. Ngakho-ke, kufanele utshele udokotela wakho ngayo yonke imithi oyithathayo (kufaka phakathi amavithamini, amakhambi, kanye namatiye emithi). Ingase ihlangane nemithi elandelayo:
| Ungalokothi uthathe lezi ne-lorlatinib. | |
|---|---|
| apalutamide, enzalutamide, mitotane, ranolazine | Imithi enikezwayo yezinhlobo ezahlukene zomdlavuza kanye nezifo zenhliziyo |
| Imithi yokulwa nesifo sokuwa efana ne-carbamazepine, i-phenytoin, ne-phenobarbital | Imithi yokwelapha ukuxhuzula |
| i-rifampin, i-rifapentine | Ama-antibiotic okutheleleka ngamagciwane njengesifo sofuba |
| I-St. John's Wort | Isengezo semifino sokucindezeleka |
| i-lumacaftor; i-ivacaftor | Imithi ye-Cystic Fibrosis |
| Ungase usabele ngalezi zinto - buza udokotela wakho. | |
| Ama-antibiotic | Isibonelo: i-clarithromycin |
| Imithi yokulwa nesikhunta | Isibonelo: i-ketoconazole, i-itraconazole, i-fluconazole |
| Imithi ye-HIV kanye ne-hepatitis | Isibonelo: i-ritonavir, i-boceprevir |
| Ama-hormone kanye nokulawula ukuzalwa | Izinto ezifana namaphilisi okuvimbela inzalo, ama-patches, imijovo, njll. |
| Eminye imithi | i-bosentan, i-modafinil, i-midazolam |
Izinto okufanele uzikhumbule lapho uthatha imithi
Kuvamile ukuzizwa ungakhululekile ngesikhathi sokwelashwa komdlavuza, njengoba kuthinta amangqamuzana omdlavuza kanye namaseli anempilo. Kodwa ungayeki ukwelashwa kuze kube yilapho udokotela wakho ekuyala. Yazisa udokotela wakho nganoma yimiphi imiphumela emibi.
Izeluleko zokukhulelwa, ukuncelisa kanye nabesilisa
Lesi sigaba sibaluleke kakhulu. Sicela ulalelisise.
- Kwabesifazane: Gwema ukukhulelwa ngokuphelele ngenkathi uthatha lo muthi. Futhi, gwema ukukhulelwa izinyanga eziyi-6 ngemuva kokuyeka umuthi. Sebenzisa indlela yokuvimbela inzalo engeyona eye-hormone (isib. amakhondomu, i-copper T). Tshela udokotela wakho ngokushesha uma usola ukuthi ukhulelwe. Gwema ukuncelisa ngenkathi uthatha umuthi kanye nezinsuku eziyi-7 ngemuva kokuyeka umuthi.
- Kwabesilisa:Amadoda asebenzisa lo muthi kufanele asebenzise ikhondomu uma eya ocansini nowesifazane ongakhulelwa. Le ndlela yokuvimbela inzalo kufanele iqhubeke izinyanga ezi-3 ngemva kokuyeka umuthi. Uma usola ukuthi umlingani wakho ukhulelwe, yazisa udokotela wakho ngokushesha.
Izifo kanye nomkhuhlane
Lo muthi ungase wehlise amasosha omzimba wakho futhi wandise ingozi yokuthola izifo. Ngakho-ke, uma ubona izimpawu ezifana nomkhuhlane, umkhuhlane, umphimbo obuhlungu, noma ukukhwehlela, ungaziphilisi bese ushayela udokotela wakho ngokushesha ukuze akunike iseluleko. Zama ukungahlangani nabantu abagulayo.
Amazinga e-cholesterol kanye noshukela
I-Lorlatinib ingakhuphula i-cholesterol yegazi (ikakhulukazi ama-triglyceride) kanye namazinga kashukela egazini. Inganciphisa ne-cholesterol enhle (i-HDL). Udokotela wakho uzokuhlola lokhu njalo. Uma kudingeka, bangase batuse ukushintsha ukudla noma imithi emisha.
Izinguquko empilweni yengqondo
Lo muthi ungathinta abanye abantu ngokwengqondo. Tshela udokotela wakho ngokushesha uma wena noma ilungu lomndeni wakho nibona noma yiluphi ushintsho olulandelayo:
- Ukucindezeleka okusha noma okubi kakhulu
- Imicabango yokuzilimaza
- Ukukhathazeka
- Ukulahlekelwa yinkumbulo
- Ukuziphatha noma imicabango engavamile, ephazamisayo
Yimiphi imiphumela emibi engabonakala?
Njenganoma yimuphi umuthi, i-lorlatinib ingaba nemiphumela emibi. Eminye yale miphumela ingaba mibi kakhulu futhi kufanele ibikwe ngokushesha.
| Imiphumela emibi okufanele ibikwe kudokotela wakho ngokushesha | |
|---|---|
| Ukusabela kokungezwani komzimba | Ukuqubuka kwesikhumba, ukulunywa, ukuvuvukala kobuso, izindebe, noma ulimi |
| Ubuhlungu besifuba noma ukuqina | Kungaba izimpawu zokuhlaselwa yinhliziyo |
| Ukukhwehlela, ubunzima bokuphefumula, ukuvuvukala komzimba (i-edema) | Ukukhuluphala okungazelelwe, ukuvuvukala kwamaqakala, izandla nezinyawo |
| Izimpawu zokulimala kwesibindi | Umchamo ophuzi omnyama noma onsundu, ukuphuzi kwamehlo/isikhumba, ubuhlungu ohlangothini oluphezulu lwesokudla lwesisu |
| Izimpawu zokutheleleka | Umkhuhlane, ukubanda, umphimbo obuhlungu |
| Izimpawu zokubalwa kwamaseli egazi aphansi | Ubunzima bokuphefumula, ukukhathala okukhulu, ukuquleka, ikhanda elibuhlungu |
| Izinguquko zengqondo noma isifo sokuwa | Izimpawu zengqondo ezingenhla, ukudideka, ukuxhuzula |
| Tshela udokotela wakho uma kuqhubeka noma kuyakhathaza. | |
| Isicanucanu, ukuhlanza | Umfutho wegazi okhuphukile |
| Ukushintsha kombono, umbono ofiphele | Amazinga e-cholesterol akhuphukile |
| Ukungalali kahle noma ukuncipha kokulala | Ukulahlekelwa inkumbulo, ukucasuka |
Umlayezo Wokuya Nawe Ekhaya
- Phuza umuthi njengoba nje udokotela wakho ekuyalele, ngesikhathi esifanele, nangomthamo ofanele. Ungalokothi uphule noma uchoboze iphilisi.
- Tshela udokotela wakho ngayo yonke eminye imithi, amavithamini, kanye nemikhiqizo yamakhambi oyithathayo. Ikakhulukazi gwema ukuphuza ijusi yamagilebhisi.
- Gwema ukukhulelwa ngenkathi uthatha lo muthi futhi isikhathi eside njengoba udokotela wakho encoma. Abesifazane nabesilisa kufanele baqaphele lokhu.
- Uma uhlangabezana nanoma yimiphi imiphumela emibi efana nobunzima bokuphefumula, ubuhlungu besifuba, ukuvuvukala okukhulu, noma ushintsho olukhulu esimweni sengqondo, funa iseluleko sezokwelapha ngokushesha.
- Lo muthi ungowakho kuphela. Ungawabelani nabanye nganoma yisiphi isizathu.
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