Ake sifunde ngemithi yesifo i-Alzheimer's

Uma sithola ukuthi umama wethu, ubaba, noma othile oseduze nathi unesifo i-Alzheimer's, sizizwa sidabuka kakhulu futhi sikhathazekile. Kunzima kakhulu ukubona inkumbulo yabo inyamalala kancane kancane bese bekhohlwa izinto. Kodwa ungakhathazeki. Nakuba kungekho ikhambi lalesi sifo, kunezinhlobo eziningana zemithi engasiza ekulawuleni izimpawu, yehlise ijubane lokuqhubeka kwalesi sifo, futhi yenze impilo yabo ibe lula kancane. Namuhla, sizoxoxa ngaleyo mithi.

Kwenzekani ebuchosheni ngesifo i-Alzheimer's?

Ngaphambi kokuba sikhulume ngalo muthi, ake siqonde kalula ukuthi kwenzekani ebuchosheni esifweni i-Alzheimer's. Imiyalezo idluliselwana phakathi kwamangqamuzana ezinzwa ebuchosheni bethu ngamakhemikhali. Esifweni i-Alzheimer's, amaprotheni angajwayelekile (i-amyloid ne-tau) aqala ukuqongelela ebuchosheni. Lokhu kulimaza amangqamuzana ezinzwa futhi kuphazamise ukuxhumana phakathi kwawo. Lokhu kunomthelela omkhulu ezingxenyeni zobuchopho ezilawula inkumbulo, ukucabanga, nokuziphatha .

Imithi yamanje ilawula kakhulu le nqubo. Eminye imithi ilinganisela amazinga ezithunywa zamakhemikhali ebuchosheni, kuyilapho imithi emisha izama ukususa ama-protein deposits angajwayelekile.

Imithi eyinhloko yesifo i-Alzheimer's

Imithi yesifo i-Alzheimer's ingahlukaniswa ngezigaba ezimbili eziyinhloko. Eyokuqala imithi elawula izimpawu. Eyokuqala imithi emisha ezama ukulawula ukuqhubeka kwesifo, okungukuthi, ukuba mandundu kwalesi sifo.

1. Ama-Cholinesterase Inhibitors

Lena imithi evame kakhulu ukunikezwa iziguli ezisesigabeni sokuqala nesephakathi sesifo i-Alzheimer's.

Zisebenza kanjani?

Kalula nje, ubuchopho bethu bunesithunywa samakhemikhali esibizwa ngokuthi i-acetylcholine , esibalulekile ezintweni ezifana nenkumbulo nokufunda. Esifweni i-Alzheimer's, amazinga ale acetylcholine ayancipha. Lokho okwenziwa yile mithi ukuvimba ukuwohloka kwe-acetylcholine ebuchosheni. Lokhu kuvumela ukuthi imiyalezo ithunyelwe phakathi kwamangqamuzana ezinzwa kangcono kancane.

Yiziphi imiphumela emibi yalokhu?

Akuwona wonke umuntu othola imiphumela emibi, kodwa abanye abantu bangase babe nesicanucanu, ukuhlanza, isisu esibuhlungu, ukuqunjelwa, kanye nokukhathala.

2. I-Memantine

Lo muthi uvame ukunikezwa abantu abasesigabeni esiphakathi kuya kwesikhulu salesi sifo. Ngezinye izikhathi, udokotela angase awunikeze kanye ne-Donepezil okukhulunywe ngayo ngenhla.

Kusebenza kanjani?

Esinye isithunywa samakhemikhali ebuchosheni esibizwa ngokuthi i-glutamate siba phezulu kakhulu esifweni i-Alzheimer's. Lokhu kungalimaza amangqamuzana ezinzwa. I-Memantine isebenza ngokulawula la mazinga e-glutamate. Lokhu kungasiza ekuthuthukiseni ukunaka kwesiguli, ukucabanga, kanye nolimi. Kungasiza futhi ukulawula izimpawu ezifana nokungaphumuli, ulaka, nokubona/ukuzwa izinto ezingekho .

Imiphumela emibi: Ukuqunjelwa, isiyezi, ikhanda elibuhlungu, kanye nokozela kungase kwenzeke.

3. Imithi emisha ehlose ukugcinwa kwama-amyloid ebuchosheni

Lezi yizinyathelo zakamuva ekwelashweni kwe-Alzheimer's. Lezi yizidakamizwa ezikhethekile ezibizwa ngokuthi "ama-monoclonal antibodies." Lezi zihlose ngqo ama-protein deposit ayingozi abizwa ngokuthi ama-amyloid plaques aqoqana ebuchosheni. Anikezwa ngemithambo yegazi (IV). Okwamanje avunyelwe kuphela iziguli ezisesigabeni sokuqala salesi sifo.

• I-Lecanemab (i-Leqembi)
• I-Donanemab (Kisunla)

Le mithi iboniswe ezivivinyweni ukuthi inciphisa kakhulu ukuqhubeka kwalesi sifo. Kodwa-ke, ingabangela imiphumela emibi eyingozi njengokuvuvukala kwesikhashana kobuchopho noma ukuphuma kwegazi okuncane, ngakho-ke inikezwa ngokucophelela kakhulu futhi kuphela ngaphansi kokuqashwa okuseduze kukadokotela.

Izinto okufanele uziqaphele lapho unikeza isiguli umuthi

Njengomnakekeli womuntu one-Alzheimer's, unomthwalo wemfanelo omkhulu, ikakhulukazi ukumnikeza imithi yakhe ngesikhathi. Kunezinto ezimbalwa okudingeka uzazi.

Ezigabeni zokuqala zesifo:

Nakuba isiguli singase sikwazi ukuphuza imithi ngokwaso ekuqaleni, singase sikhohlwe kancane kancane ngayo. Yenza lezi zinto ukuze usisize.

• Sebenzisa umhleli wamaphilisi: Gcina imithi yakho ihlelekile isonto lonke. Kungcono ukuba neyodwa enezingxenye zasekuseni, ntambama nakusihlwa.
• Zikhumbuze ngesikhathi: Setha i-alamu efonini yakho. Noma, uma ukwazi, shayela ucingo bese uzikhumbuza ngaleso sikhathi.
• Khuluma nabo: Babuze ngothando, "Ngingakusiza yini ukuthola imithi yakho?" Basize ngenkathi uhlonipha ukuzimela kwabo.

Uma isifo sibi kakhulu:

Ngokuhamba kwesikhathi, kuzodingeka uthathe umthwalo wemfanelo ophelele wokunikeza imithi.

• Uma unenkinga yokugwinya amaphilisi: Kungenzeka ukuthi umlomo wakho womile. Nika ingane yakho amanzi ngaphambi kokuyinika umuthi. Kodwa uma lokho kungasebenzi, buza udokotela wakho ukuthi umuthi ungachotshozwa yini bese uxutshwa nokudla, noma uma utholakala uketshezi. Akuyona yonke imithi elungele ukuchotshozwa , ngakho qiniseka ukuthi ubuza udokotela wakho.
• Uma bethi abakwazi ukuthatha umuthi: Ungalwi nabo. Lokho kuzobenza bacasuke kakhulu. Ngaleso sikhathi, yeka ukuwuthatha, linda isikhashana, bese uzama futhi. Mhlawumbe bazowuthatha uma ubakhumbuza ngobumnene ukuthi, "Lona umuthi wenkinga yakho." Uma beqhubeka nokwenqaba, tshela udokotela wakho.
• Gcina uhlu lwemithi: Bhala phansi yonke imithi, amavithamini, kanye nomthamo abawuthathayo, nokuthi bawuthatha nini. Hamba nalolu hlu uma uya kudokotela.
• Gcina imithi yakho iphephile: Gcina yonke imithi ekhabetheni elikhiyiwe, kude nezingane kanye nesiguli.