Ingabe ingalo noma umlenze wakho ukhuluphele ngendlela engajwayelekile? Ake sifunde ngalesi sifo samathambo esingavamile (i-Melorheostosis)!

Ingabe wena noma ingane yakho ngezinye izikhathi nizizwa ukujiya noma ukuqina okungajwayelekile engalweni noma emlenzeni, noma nje ukuthungwa kokhuni? Noma ingabe ingalo noma umlenze owodwa ubonakala ukhuluphele kunomunye? Ingabe awukwazanga ukugoba noma ukuqondisa ilunga kahle kusukela ebuntwaneni futhi uzwa ubuhlungu? Lezi akuzona nje izinto ezingahleliwe. Namuhla sizokhuluma ngesifo samathambo esingavamile kakhulu esingaba yisisusa salezi zinto.

Iyini lesi sifo esingajwayelekile (iMelorheostosis)?

Kalula nje, iMelorheostosis isifo samathambo esingavamile kakhulu. Kulokhu, izicubu ezintsha zamathambo ziqala ukwakheka ezingqimbeni zangaphandle zamathambo ethu, ezibizwa ngokuthi amathambo e-cortical. Cabanga ngakho njengokwengeza olunye ungqimba lweplasta odongeni, bese kwakheka amathambo engeziwe phezu kwelinye lamathambo ethu. Ngakho-ke kwenzekani-ke? Lelo thambo liya likhula libe likhulu.

Ngokuvamile kuthinta uhlangothi olulodwa lomzimba, kungaba ingalo noma umlenze. Kodwa-ke, kungathinta namanye amathambo, njenge-hip noma i-sternum. Izimpawu zivame ukuqala ebuntwaneni noma ebusheni .

Enye into ekhethekile ngalokhu yindlela leli thambo elisanda kwakheka elibukeka ngayo ku-X-ray. Odokotela balichaza njenge-wax encibilikisiwe evela ekhandleleni ephumile futhi iyaconsa . Yingakho libizwa nangokuthi 'i-wax yekhandlela econsa'. Kuyamangalisa kakhulu, akunjalo?

I-Meloriostosis empeleni uhlobo lwe-skeletal dysplasia. Iyaziwa nangokuthi isifo i-Leri.

Igama elithi "meloriostosis" lavela kanjani?

Igama elithi 'Melorheostosis' lingase libonakale lishintsha kancane uma ulizwa, akunjalo? Kodwa uma usuyazi incazelo yaleli gama, ungathola umbono ngalesi sifo. Leli gama lakhiwa ngokuhlanganisa amagama amathathu olimini lwesiGreki. Ake sibone ukuthi ayini?

• Igama elithi 'Melos' lisho isandla noma unyawo , okungukuthi, ingxenye yomzimba wethu.
• 'Rheos' kusho ukugeleza . Njengomfula ogeleza.
• 'I-Ostosis' isho ukwakheka kwamathambo .

Manje usuyaqonda, akunjalo? Uma la magama amathathu ehlanganiswa, igama liveza uhlobo lokwakheka kwamathambo, njenge-wax ephuma ekhandleleni esikhulume ngalo ngaphambili. Igama elifaneleka kakhulu, akunjalo?

I-meloriostosis ithinta kanjani umzimba?

Uma wena noma ingane yakho ninesifo se-meliorostosis, amathambo amakhulu ngendlela engavamile anganciphisa ukunyakaza kwenu. Isibonelo, ungase ungakwazi ukuphakamisa ingalo kahle noma ukugoba noma ukuqondisa umlenze kahle. Ungase futhi ube nokukhubazeka kwamalunga (ukugoba). Lokhu kusho ukuthi ilunga liyavaleka endaweni yalo. Abanye abantu bangase babe nobuhlungu obukhulu.Kungenzeka ukuthi kuzokwenzeka.

Kanye nalezi zinguquko emathanjeni, ungase ubone nezinguquko esikhumbeni . Isikhumba singase sibe sikhulu noma sibe nokubukeka okukhazimulayo, njengokungathi sicwebezelisiwe.

Ingxenye engcono kakhulu ukuthi i-meloriostosis ayisabalali isuka kwelinye ithambo iye kwelinye. Lokhu kusho ukuthi uma isesandleni esisodwa, ngeke isabalale iye kwesinye. Kodwa-ke, lesi simo singaba sibi kancane ngokuhamba kwesikhathi. Lokhu kusho ukuthi ubuhlungu bungakhula futhi ukunyakaza kungase kuncishiswe kakhulu.

Sivame kangakanani lesi sifo?

I-Meloriostosis empeleni iyisifo esingavamile kakhulu. Esingavamile kakhulu, kangangokuthi ochwepheshe bathi lesi sifo sitholakala kubantu abacishe babe munye kwabayisigidi emhlabeni jikelele. Lokho kusho ukuthi ngisho naseSri Lanka, laba bantu bambalwa kakhulu.

Kungani kwenzeka le meloriostosis? Iyini imbangela?

Ungase umangale ukuzwa lokhu. Kwabanye abantu, cishe oyedwa kwababili, abathola lesi sifo, imbangela ukuguquka kwezakhi zofuzo. Sinezakhi zofuzo ezibizwa ngokuthi 'MAP2K1' emizimbeni yethu. Lesi sakhi sofuzo senza iphrotheni ekhethekile elawula ukukhula kwamangqamuzana ethu amathambo. Ngakho-ke, uma kukhona ushintsho, okungukuthi, 'ukuguqulwa', kulesi sakhi sofuzo 'MAP2K1', lesi simo se-meloriostosis singenzeka.

Into ebalulekile ukuthi lokhu kushintshashintsha kwezakhi zofuzo kwenzeka 'ngezikhathi ezithile'. Okusho ukuthi, akuyona into ezuzwe njengefa kubazali. Cabanga nje, njengelotho, lokhu kushintshashintsha kwezakhi zofuzo kungenzeka kumuntu ngengozi.

Kodwa-ke, akubona bonke abantu abane-meloriostosis abanalo lolu guquko lwezakhi zofuzo lwe-'MAP2K1'. Kukhona abanye abantu abanalesi sifo ngaphandle kwalolu guquko lwezakhi zofuzo. Ngakho-ke ezimweni ezinjalo, odokotela abakakwazi ukuthola ukuthi yini ngempela ebangela lesi sifo. Ucwaningo olwengeziwe luyenziwa ngalokho.

Ziyini izimpawu ze-meloriostosis?

Cishe umuntu oyedwa kwababili abane-meloriostosis uqala ukukhombisa izimpawu ngaphambi kokuba afinyelele eminyakeni engama-20. Ngokuvamile, lezi zimpawu ziqala ebuntwaneni, ngezinye izikhathi zingakapheli izinsuku ezimbalwa zokuzalwa . Ngokuhamba kwesikhathi, lezi zimpawu zingase zibe zimbi kakhulu .

Lezi zimpawu zivame ukubonakala kakhulu engalweni noma emlenzeni. Kodwa-ke, akuvamile kakhulu, wena noma ingane yakho ningase nibe nalezi zimpawu kwezinye izindawo, njengesinqe, ithambo eliphakathi lesifuba (sternum), noma izimbambo. Ake sibheke izimpawu eziyinhloko:

• Ubuhlungu obungapheli: Lokhu kusho ubuhlungu obuhlala isikhathi eside. Lena yinkinga enkulu kubantu abaningi.
• Isikhumba esijiyile noma esicwebezelayo: Isikhumba singase sibukeke sengathi sicwebezelwe kahle. Singase sizizwe siqinile uma usithinta.
• Ukuvuvukala engalweni noma emlenzeni: Lokhu kuvuvukala kungabangelwa ukugcinwa koketshezi (i-edema) noma ukuvuvukala kwama-lymph node (i-lymphedema).
• Ububanzi obulinganiselwe bokunyakaza:Isibonelo, ukungakwazi ukugoba indololwane ngokuphelele noma ukwelula idolo ngokugcwele.
• Ukuwohloka kwemisipha: Imisipha engalweni noma emlenzeni othintekile ingase iwohloke kancane kancane.
• Ubude obungalingani bengalo noma umlenze: Ingalo eyodwa ingaba mfushane kunenye, noma umlenze owodwa ungaba mfushane kunenye. Lokhu kungabangela nobunzima bokuhamba.

Itholakala kanjani i-meloriostosis?

Odokotela basebenzisa kakhulu izivivinyo ezikhethekile zokuthwebula izithombe ukuze bathole i-meloriostosis.

Phakathi kwazo:

• Ukuskena kwamathambo: Lokhu kuhilela ukufaka umthamo omncane wento ekhipha imisebe emzimbeni bese uyibheka ngekhamera ekhethekile. Lokhu kuvumela umbono ocacile wanoma yikuphi ukukhubazeka emathanjeni.
• Ama-X-ray: Lokhu kuyinto okungenzeka ukuthi uyazi. Isebenzisa umthamo ophansi wemisebe ukubheka amathambo nezicubu ezithambile. Uma ubheka i-X-ray yomuntu one-meloriostosis, uzobona lokho kubukeka "kwe-wax econsayo" esikhulume ngakho ekuqaleni. Lokhu kuyisibonakaliso esibaluleke kakhulu ekuxilongweni kwalesi sifo.

Ngaphezu kwalezi zivivinyo zokuthwebula izithombe, ngezinye izikhathi odokotela bangase batuse nokuhlolwa kwezakhi zofuzo . Lokhu kwenziwa ngokuthatha isampula yegazi. Lezi zivivinyo zezakhi zofuzo zibheka ukuba khona kokuguqulwa kwezakhi zofuzo kwe-MAP2K1 esikhulume ngakho ngaphambili.

Yiziphi izindlela zokwelapha lokhu? Ingabe kungelapheka?

Uma ngikhuluma iqiniso, alikho ikhambi le-meloriostosis okwamanje. Lokhu kungase kuzwakale kudabukisa kancane ukuzwa. Kodwa ungakhathazeki. Kunezindlela eziningi zokwelapha ezingakusiza wena nomntanakho niphile impilo engcono ngokulawula izimpawu.

Odokotela bavame ukuncoma ukwelashwa okufana nalokhu ukuze banciphise ubuhlungu futhi bathuthukise ukusebenza komzimba:

• Ukwelashwa ngokomzimba: Lokhu kuhilela ukusebenzisa izivivinyo ezikhethekile kanye nokwelashwa ukusiza ukwandisa amandla omzimba nokwandisa ububanzi bokunyakaza kwamalunga. Isibonelo, uma unenkinga yokugoba ingalo yakho, ungase ufundiswe izivivinyo ezizokusiza.
• Ukwelashwa Komsebenzi: Lokhu kusiza ekuthuthukiseni amakhono okunyakaza komzimba. Okusho ukuthi, imisebenzi emincane eyenziwa ngeminwe, njengokuzicindezela, ukubhala, njll. Futhi, ukusiza ingane ukuthi yenze imisebenzi yansuku zonke ngokuzimela, njengokugeza nokugqoka, kuyingxenye yalolu hlobo lokwelashwa.
• Imithi:
• Izibulali-zinhlungu: Izibulali-zinhlungu, njengemithi engeyona eye-steroidal elwa nokuvuvukala (ama-NSAID), zinikezwa ukunciphisa ubuhlungu.
• Ama-Bisphosphonates: Lawa anikezwa ukuqinisa amathambo.
• Ukuhlinzwa:Kwezinye izimo, kungase kudingeke ukuhlinzwa ukuze kususwe ithambo elisha elengeziwe noma kuphinde kuklanywe ithambo. Kodwa-ke, lokhu kwenziwa kuphela uma ezinye izindlela zokwelapha zinganikezi impumuzo.

Okubalulekile: Akuzona zonke lezi zindlela zokwelapha ezifanele wonke umuntu. Udokotela wakho uzonquma ukuthi yikuphi ukwelashwa okufanele isimo sakho.

Ingabe ikhona indlela yokuvimbela i-meloriostosis ukuthi ingakhuli?

Lezi yizindaba ezidabukisayo kancane. Ngenxa yokuthi i-meloriostosis yisifo esenzeka ngokungahleliwe, okusho ukuthi senzeka ngaphandle kwesizathu esicacile , akukho lutho esingakwenza ukuvimbela ukuthi singakhuli. Ihlobene nokuguqulwa kwezakhi zofuzo, ngakho-ke kuyinto engaphezu kwamandla ethu.

Iyini imiphumela yesikhathi eside yalesi sifo?

I-Meloriostosis ayiyona umdlavuza. Ngakho-ke akukho okufanele ukhathazeke ngakho. Futhi, lesi sifo asifinyezi isikhathi sakho sokuphila. Lezi yizindaba ezinhle kakhulu.

Kodwa-ke, lesi sifo singanciphisa ukusebenza komzimba kanye nokunyakaza kwawo. Kungase kudingeke uphile nezinto ezifana nobuhlungu nokuvuvukala emalungeni. Kodwa-ke, ngohlelo lokwelashwa olufanele, abantu abane-meloriostosis bangaphila impilo esezingeni eliphezulu. Lokho kusho ukuthi bangaphila ngenjabulo futhi benze umsebenzi wabo njengawo wonke umuntu.

Yini enye okufanele ngiyibuze udokotela?

Uma wena noma ingane yakho ninezimpawu ze-meloriostosis, noma senivele nitholakale ukuthi ninayo le nkinga, kubalulekile ukubuza udokotela wakho imibuzo efana nale:

• "Yiziphi izimpawu zokuqala ze-meloriostosis?"
• "Yiziphi izivivinyo okufanele ngizenze ukuze ngithole lesi sifo ngokunembile?"
• "Yiziphi izindlela zokwelapha enginazo? Yikuphi ukwelashwa okungcono kakhulu kimi?"
• " Kungenzekani uma ngingakuphathi lokhu?"
• "Yini engingayenza ukuze ngithuthukise ikhwalithi yokuphila kwami ​​​​nge-meloriostosis?"

Buza le mibuzo ukuze uqonde kangcono isimo sakho. Khuluma nodokotela wakho ngokukhululekile.

Zikhona yini ezinye izifo ezinezimpawu ezifana ne-meloriostosis?

Yebo, kunezinye izimo eziningana ezingabangela izimpawu ezifana neze-meloriostosis. Udokotela wakho uzokhipha lezi zimo lapho exilonga. Ezinye zalezi zimo zifaka:

• I-Buschke-Ollendorff syndrome
• Isimila se-Desmoid
• I-Hemangioma
• I-Osteopathy
• I-Osteopoikilosis
• I-Scleroderma

Yingakho kubaluleke kakhulu ukwenza ukuxilongwa okunembile.

Okokugcina, izinto okufanele uzikhumbule

I-Melorheostosis isifo samathambo esingavamile kakhulu.Lokhu kwenzeka lapho kwakheka izicubu ezintsha zamathambo phezu kwethambo elikhona. Ngokuvamile kuthinta ingalo noma umlenze owodwa. Nakuba kungasabalali kusuka kwelinye ithambo kuya kwelinye, lesi simo singaba sibi kakhulu ngokuhamba kwesikhathi.

Uma une-meloriostosis, ungesabi. Kunezindlela zokwelapha ezitholakalayo, njengemithi, ukwelashwa ngokomzimba, ukwelashwa ngokomsebenzi, noma ukuhlinzwa. Lezi zindlela zokwelapha zingakusiza ukunciphisa ubuhlungu, ubuyele emisebenzini evamile, futhi uphile impilo engcono. Into ebaluleke kakhulu ukufuna iseluleko sezokwelapha ngokushesha okukhulu uma unezimpawu futhi ulandela imiyalelo kadokotela wakho ngokucophelela.

I- Melorheostosis, isifo samathambo, ukukhula kwamathambo, ubuhlungu bamalunga, imikhawulo yokunyakaza, ukuguquka kwezakhi zofuzo, izifo zezingane