Ingabe wena noma othile omaziyo une -hemolytic anemia ebangelwa ukuntuleka kwe-enzyme okubizwa ngokuthi ukuntuleka kwe-pyruvate kinase? Lesi yisimo esingavamile. Ezimweni ezinjalo, udokotela wakho kungenzeka ukuthi ukunike iphilisi elibizwa ngokuthi iMitapivat. Ungase uzizwe udidekile kancane uma uzwa leli gama. Ngakho-ke, namuhla sizokhuluma kalula nangomusa ngalo muthi obizwa ngokuthi iMitapivat (igama lomkhiqizo elithi PYRUKYND).
Kalula nje, iyini le Mitapivat?
I-Mitapivat umuthi okhethekile onikezwa ukwelapha i-hemolytic anemia ebangelwa yisimo esibizwa ngokuthi i-pyruvate kinase deficiency. Manje ungase uzibuze, "Kuyini i-hemolytic anemia?"
Kulula kakhulu. Sinohlobo lweseli legazi elibizwa ngokuthi amangqamuzana egazi abomvu emzimbeni wethu. Lawa maseli athwala umoya-mpilo kuwo wonke umzimba wethu. Ngokuvamile, lawa maseli abomvu egazi aphila cishe izinsuku ezingu-120. Kodwa-ke, emzimbeni womuntu onesifo se-pyruvate kinase, lawa maseli abomvu egazi ayaphuka futhi abhujiswe kusenesikhathi, ngokushesha. Yilokho okubizwa ngokuthi i-hemolytic anemia.
Ngakho-ke, lokho okwenziwa yiMitapivat ukuvimba ukuwohloka okusheshayo kwamangqamuzana abomvu egazi. Uma sikhuluma iqiniso, inikeza lawo maseli amandla futhi yandisa isikhathi sawo sokuphila . Lokhu kwenzani?
- Inani lamaseli abomvu egazi emzimbeni liyakhula.
- Izimpawu ze- anemia ezifana nokukhathala, ukukhathala njalo, kanye nokuphelelwa umoya ziyancishiswa.
- Isidingo sokumpontshelwa igazi njalo naso sinciphile.
Lokho kusho ukuthi lo muthi uzokusiza ukuthuthukisa ikhwalithi yempilo yakho.
Izinto okudingeka uzitshele udokotela wakho ngaphambi kokuthatha lo muthi
Ngaphambi kokusebenzisa noma yimuphi umuthi, kubaluleke kakhulu ukunikeza udokotela wakho incazelo ephelele yesimo sakho sempilo. Ngaphambi kokuthi uqale ukuthatha iMitapivat, qiniseka ukuthi utshela udokotela wakho uma unezinye zezimo ezilandelayo:
- Isifo sesibindi: Uma unesifo sesibindi esivele sikhona, sicela usitshele ngaso.
- Ukungezwani komzimba :Uma une-allergy ku-Mitapivat, noma yimuphi omunye umuthi, ukudla, udayi, noma izithasiselo, qiniseka ukuthi usazise.
- Ukukhulelwa : Uma ukhulelwe noma uzama ukukhulelwa maduze, khuluma nodokotela wakho ngakho.
- Uma ungumama oncelisayo: Uma ungumama oncelisayo, kufanele futhi utshele udokotela.
Ngokusekelwe kulolu lwazi, udokotela wakho uzonquma ukuthi lo muthi ukulungele yini noma ukuthi umthamo udinga ukushintshwa.
Ungayisebenzisa kanjani imithi ngendlela efanele?
Ukuze uthole okuningi ngomuthi, kubaluleke kakhulu ukuwusebenzisa ngendlela efanele.
- Lo muthi uyiphilisi oliphuza ngomlomo. Zama ukuwuthatha ngesikhathi esifanayo nsuku zonke , njengoba nje udokotela wakho ekuyalele.
- Gwinya ithebhulethi lonke ngamanzi. Ungalokothi uliphule, ulichoboze, noma ulihlafune ithebhulethi.
- Qhubeka uthatha lo muthi kuze kube yilapho udokotela wakho ekutshela ukuthi uyeke. Ungayeki ukuwuthatha ngokuzumayo, noma ngabe uzizwa ungcono.
- Lo muthi ungadinga ukunakekelwa okukhethekile uma unikezwa izingane. Ngakho-ke, landela imiyalelo kadokotela wakho ngokucophelela.
Yini okufanele uyenze uma uthatha umuthi omningi kakhulu? (Umthamo oweqile)
Ake sithi ngephutha uphuze umuthi omningi kunomthamo onqunyiwe. Uma lokho kwenzeka, ungalibali. Yiya esibhedlela esiseduze i-Emergency Treatment Unit (ETU) ngokushesha. Ngaphandle kwalokho, shayela i-National Poisons Information Centre e-Colombo National Hospital ukuze uthole iseluleko.
Lo muthi unikezwe wena kuphela. Ungalokothi uwuhlanganyele nanoma ubani omunye, noma ngabe unezimpawu ezifanayo nezakho.
Kuthiwani uma ngiphuthelwa umthamo wemithi?
Njengoba impilo imatasa, ngezinye izikhathi ungase uphuthelwe umthamo wemithi. Uma lokho kwenzeka, nakhu okufanele ukwenze:
- Thatha umuthi wakho ngokushesha nje lapho ukhumbula.
- Kodwa-ke, uma uphuthelwa umthamo ngamahora angaphezu kwamane, yeqa lowo mthamo ngokuphelele. Thatha umthamo wakho olandelayo ngesikhathi esihleliwe.
- Ungathathi umthamo ophindwe kabili ukuze ubuyisele umthamo ophuthelwe nganoma yisiphi isizathu.
Eminye imithi engase ihlangane nalo muthi
Eminye imithi oyithathayo ingase ixhumane neMitapivat. Lokhu kungashintsha indlela iMitapivat esebenza ngayo noma kwandise imiphumela emibi. Ngakho-ke, qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyithathayo (kufaka phakathi amavithamini, amakhambi, kanye nemithi enqunywe abanye odokotela).Tshela udokotela wakho.
Ngezansi kuneminye imithi engase ihlangane neMitapivat.
| Isigaba sezidakamizwa | Izibonelo |
|---|---|
| Eminye imithi yokwelapha izifo zesikhunta | I-Fluconazole, i-Itraconazole, ne-Ketoconazole |
| I-Efavirenz (umuthi we-HIV) | I-Efavirenz |
| Ama-hormone e-estrogen ne-progestin | Amaphilisi okuvimbela inzalo, ukwelashwa ngama-hormone |
| I-Midazolam | Umuthi osetshenziselwa ukuzola noma ukudambisa ubuhlungu |
| I-Rifampin | I-antibiotic enikezwa izifo ezifana nesifo sofuba |
Okubalulekile: Lolu hlu aluphelele. Tshela udokotela wakho uma ubhema, uphuza utshwala, noma usebenzisa ezinye izidakamizwa.
Izinto okufanele uziqaphele lapho uthatha umuthi
Ngesikhathi uthatha lo muthi, udokotela wakho uzohlola impilo yakho njalo.
- Yiya emihlanganweni yomtholampilo ehleliwe. Lokhu kubaluleke kakhulu ukuze ubone ukuthi uqhuba kanjani nokuthi imithi iyasebenza yini.
- Uma izimpawu zakho zingathuthuki, noma ziba zimbi kakhulu, tshela udokotela wakho.
- Ungase ucelwe ukuthi wenze ukuhlolwa kwegazi ngenkathi uthatha lo muthi. Ungayeqi le mihlolo bese uyenza njalo.
Yimiphi imiphumela emibi engaba khona?
Njengayo yonke imithi, iMitapivat ingabangela imiphumela emibi, yize kungebona bonke abantu abayitholayo. Eminye imiphumela emibi ingaba mibi kakhulu, ngakho-ke kubalulekile ukuyiqaphela.
| Umphumela ongemuhle | Incazelo |
|---|---|
| Imiphumela emibi okufanele ibikwe kudokotela wakho ngokushesha | |
| Ukusabela kokungezwani komzimba | Ukuqubuka kwesikhumba, ukulunywa, ukuvuvukala kobuso, izindebe, ulimi noma umphimbo, ubunzima bokuphefumula. |
| Ukuwohloka kwe-hemolytic anemia | Ukuzizwa ukhathele/ukhathele kakhulu kunokujwayelekile, isiyezi, ikhanda elibuhlungu, ubunzima bokuphefumula, umchamo omnyama, ukuphuzi kwesikhumba noma amehlo. |
| Izimpawu zokulimala kwesibindi | Ubuhlungu ohlangothini olungaphezulu kwesokudla lwesisu, ukulahlekelwa yisifiso sokudla, isicanucanu, indle ephuzi, umchamo ophuzi noma onsundu omnyama, ukuphuzi kwesikhumba noma amehlo, ubuthakathaka obungavamile. |
| Tshela udokotela wakho uma kuqhubeka noma kuyakhathaza. | |
| Ukuhlungu obusemhlane | |
| Ubuhlungu bamalunga | |
Lolu hlu aluhlanganisi yonke imiphumela emibi engaba khona. Uma uhlangabezana nanoma yiziphi ezinye izimpawu ezingavamile, khuluma nodokotela wakho ngazo.
Ungawugcina kanjani umuthi ngokuphephile?
- Gcina kude nezingane nezilwane ezifuywayo .
- Gcina endaweni yokushisa yegumbi (phakathi kwama-degree Celsius angama-20 kuya kwangu-25).
- Gcina umuthi esitsheni sokuqala owawufakwe kuso.
- Ungalokothi usebenzise imithi ephelelwe yisikhathi . Yilahle ngokuphephile.
Uma ulahla imithi ephelelwe yisikhathi noma engadingeki, kungcono ukubonisana nodokotela wakho. Kungaba ngcono ukuyilahla emgqonyeni kadoti. Uma kunjalo, khipha amaphilisi ebhodleleni, uwaxube nento efana nekhofi esetshenzisiwe, inhlabathi, noma udoti wekati, bese uwafaka esikhwameni esivalwe kahle bese uwaphonsa emgqonyeni kadoti.
Umlayezo Wokuya Nawe Ekhaya
- I-Mitapivat umuthi okhethekile owelapha i-hemolytic anemia ebangelwa ukuntuleka kwe-pyruvate kinase.
- Njalo thatha lo muthi njengoba nje udokotela wakho ekuyalele, ngesikhathi esifanele. Ungawaphuli, ungawachobozi, noma ungawahlafuni amaphilisi.
- Nikeza udokotela wakho incazelo ephelele yayo yonke eminye imithi, amavithamini, kanye nezinye izimo zezokwelapha ozithathayo.
- Funa usizo lwezokwelapha ngokushesha uma uhlangabezana nanoma yimiphi imiphumela emibi, njengokusabela kokungezwani komzimba noma izimpawu zokulimala kwesibindi.
- Lo muthi unikezwe wena kuphela. Ungalokothi uwuhlanganyele nabanye.
- Uma unenkinga ngalo muthi, khuluma nodokotela wakho.
💬 Comments (0)
Awekho amazwana athunyelwe okwamanje. Faka amazwana akho lapha okokuqala ngqa.
Engeza amazwana akho