Wake wazibuza ukuthi isibeletho, amapayipi e-fallopian, kanye nomlomo wesibeletho, izitho ezihlukile kwabesifazane, zikhula kanjani ezigabeni zokuqala zokuphila kwengane? Ngempela kuyinqubo emangalisayo neyinkimbinkimbi. Konke kuqala ngamapayipi amabili amancane athambile kakhulu, akha ngesikhathi sesigaba sombungu. Kwezokwelapha, siwabiza ngokuthi 'amapayipi e-Müllerian'. Kungenzeka ukuthi awukaze uzwe leli gama ngaphambili. Kodwa uma kukhulunywa ngempilo yokuzala yowesifazane, kubalulekile ukwazi ngaleli sistimu yamapayipi. Ngakho-ke namuhla, ake sixoxe ngakho kalula nangendlela ongayiqonda.
Kalula nje, ziyini lezi Müllerian Ducts?
Amapayipi e-Müllerian angamapayipi amabili abhangqiwe akha embungwini njengoba ekhula ngaphakathi kwesibeletho sikamama. Lawa mapayipi abizwa nangokuthi amapayipi e-paramesonephric. Kodwa-ke, igama elithi amapayipi e-Müllerian livame ukusetshenziswa.
Umsebenzi wazo oyinhloko ukudala izitho eziyinhloko zesimiso sokuzala sowesifazane. Ngokukhethekile, la mapayipi amabili yiwo akhula kamuva abe yilezi zitho:
- Isibeletho: Isitho esimangalisayo esithwala futhi sondle umntwana izinyanga eziyisishiyagalolunye.
- Amapayipi e-Fallopian: Amapayipi amabili athwala iqanda lisuka emaqanda liye esibelethweni.
- I-Cervix: Ingxenye engezansi yesibeletho exhumanisa nesitho sangasese sowesifazane.
- Ingxenye engenhla yesitho sangasese sowesifazane.
Cabanga nje, la mapayipi amabili amancane yiwo akhula abe yizitho ezibalulekile ezidingekayo ukuze abe ngumama futhi azale umntwana esikhathini esizayo.
Into emangalisayo ukuthi la mapayipi e-Müllerian akhona kuzo zonke izibungu, kungakhathaliseki ubulili, ngesikhathi sokuqala kokukhula. Pho kwenzeka kanjani ukuthi umntwana wesilisa angakhiqizi isibeletho, kodwa abe ngumntwana wesifazane kuphela?
Isizathu salokhu ukuhlukaniswa kobulili, inqubo lapho izitho zobulili zikhula khona. Ku-fetus yesilisa, kukhishwa i-hormone ekhethekile ebizwa ngokuthi i-anti-Müllerian hormone (AMH) . Le hormone iyamisa ukukhula kwemigudu ye-Müllerian futhi kancane kancane iyawohloka. Ngenxa yalokho, i-fetus yesilisa ayikhulisi izitho njengesibeletho.
Kodwa-ke, kumntwana wesifazane, le hormone ye-AMH ayikho. Ngakho-ke, imibhobho ye-Müllerian ikhula ngaphandle kwesithiyo, futhi kwakheka izitho zokuzala zesifazane okukhulunywe ngazo ngaphambili.
Ngakho-ke ayini ama-Wolffian Ducts? Uyini umehluko phakathi kwalawa amabili?
Kanye namapayipi e-Müllerian, olunye uhlelo lwamapayipi olukhona kuwo wonke umbungu wokuqala yi-Wolffian ducts. Lawa abizwa nangokuthi amapayipi e-mesonephric. Imisebenzi yala mapayipi amabili ihluke ngokuphelele komunye nomunye. Ukuze uqonde lokhu ngokucacile, bheka ithebula elingezansi.
| Isici | Amapayipi eMüllerian | Amapayipi e-Wolfian |
|---|---|---|
| Umsebenzi oyinhloko | Ukukhula kwezitho zomzimba zesimiso sokuzala sowesifazane. | Ukukhula kwezitho zomzimba zesilisa zokuzala. |
| Esibelethweni sowesifazane | Ikhula kahle futhi yakha isibeletho, amashubhu e-fallopian, njll. | Kancane kancane iyabola, ishiye izingcezu ezingabalulekile. |
| Esibelethweni sowesilisa | I-Anti-Müllerian Hormone (AMH) ibangela ukuthi ukukhula kume futhi kuphele. | Ikhula kahle ngaphansi kwethonya le-hormone i-testosterone. |
| Izitho zomzimba ezikhula futhi zakheke | Isibeletho, amapayipi e-fallopian, umlomo wesibeletho, ingxenye engenhla yesitho sangasese sowesifazane. | Ama-Vas deferens, i-epididymis, ama-vesicles esidoda. |
Kalula nje, yize zombili lezi zinhlelo zemithambo yegazi zikhona embungwini ofanayo, ngaphansi kwethonya lama-hormone, enye iyakhula kanti enye iyawohloka. Lokhu ukulinganisela okumangalisayo kwemvelo.
La mapayipi akhula kanjani futhi atholakala kuphi?
Le nqubo iqala ekuqaleni kokukhulelwa. Umntwana ukhulelwa esibelethweni ngemva kwamasonto amathathu kuya kwamane ezelwe.Le ndaba iqala cishe ngesikhathi sokukhulelwa. Ngaleso sikhathi, lawa mapayipi e-Müllerian aqala ukukhula eduze kwezinso zokuqala (izinso ze-mesonephric) embungwini. Lawa ma-renal okuqala awesikhashana, kanti izinso ezihlala njalo zikhula kamuva.
Lezi zimbobo zikhula ziyehla njengoba kuvela iminwe emide. Phakathi kwamasonto angu-8 kuya kwangu-12 okukhulelwa, izihloko zemibhobho emibili ye-Müllerian ehlayo ziyahlangana. Lokhu kuhlangana kwakha isisekelo sezitho ezifana nesibeletho kanye nesitho sangasese sowesifazane. Lezi zimbobo zakhiwe izinhlobo ezimbili ezikhethekile zamaseli.
- Amaseli e-Epithelial: Lawa anjengesivikelo sokuvikela izitho zethu futhi asiza futhi ekumunceni nasekukhipheni izinto ezibalulekile.
- Amaseli e-Mesenchymal: Lawa uhlobo lwamaseli okuqala. Lokhu kusho ukuthi lawa maseli angakhula abe izinhlobo ezahlukene zamaseli njengoba kudingeka.
Ingabe kungenzeka ukuthi kube nezinkinga ze-Müllerian duct?
Yebo, ngezinye izikhathi lawa mapayipi e-Müllerian awakhuli kahle noma awaxhumani, okubangela amaphutha ahlukahlukene kanye nokungafani. Lezi zivame ukuba yizimo zokuzalwa nazo .
Into ebalulekile ukuthi ungase ungazi ukuthi unalesi simo uze ufinyelele ebudaleni noma ushadile futhi ulindele umntwana. Ngoba kungase kungabi khona izimpawu zangaphandle. Abanye besifazane bathola ukuthi banalesi simo kuphela uma befuna izimbangela zokungazali.
Ithebula elingezansi libala ezinye zeziphambeko ezivame kakhulu ze-Müllerian duct.
| Igama le-anomaly | Kwenzekani nje? |
|---|---|
| I-Müllerian agenesis noma i-hypoplasia | Isibeletho sisuke singekho kusukela ekuzalweni (agenesis) noma sincane kakhulu futhi asikakhuli kahle (hypoplasia) . Isibonelo esivame kakhulu salokhu yisimo sofuzo i-Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome . |
| I-septum yesitho sangasese sowesifazane | Uma amapayipi amabili engahlangani kahle lapho ehlangana phansi, kwakheka ulwelwesi oluwela isitho sangasese sowesifazane. Lokhu kungabangela ukuthi isitho sangasese sowesifazane sivaleke kancane noma ngokuphelele, noma kungadalwa izitho zangasese ezimbili zowesifazane. |
| I-Persistent Müllerian duct syndrome (PMDS) | Lesi yisimo esingavamile sofuzo esithinta abafana. Ngenxa yokuthi i-hormone ye-AMH ayisebenzi kahle, isibeletho kanye namapayipi e-fallopian kukhula kanye nezitho zokuzala zabesilisa ezivamile. La madoda angase abe nezinkinga ezifana nama-testicles angakhuli. |
| Ukukhubazeka kwesibeletho | Izinkinga ngokuthuthukiswa kwe-tubal zingabangela ukuthi isibeletho sishintshe isimo. Izibonelo zifaka phakathi isibeletho esinezimbombo ezimbili, isibeletho esine-didelphys, isibeletho esinezimbombo ezimbili, kanye nesibeletho esinomumo we-T. |
Abanye abantu abanalezi ziphazamiso bangase babe nezinkinga ngezinso zabo. Lokhu kungenxa yokuthi lezi zitho ezimbili zikhula eduze kakhulu ngesikhathi sokukhulelwa, futhi iphazamiso kwelinye lingathinta elinye.
Ingabe lezi zinhlobo zamaphutha zivamile?
Cha. Akudingeki ukhathazeke ngalokhu. Lezi yizimo ezingavamile kakhulu. Ngokwezibalo, lolu hlobo lwesici lwenzeka emaphesentini amancane kakhulu okuzalwa okuphilayo, phakathi kuka -0.1% no-3.0% . Lokhu kusho ukuthi amathuba okuba into efana nale yenzeke mancane kakhulu.
Yimiphi imibuzo okufanele uyibuze udokotela?
Uma udokotela ekuxilonga wena noma ingane yakho ukuthi inesifo somgudu womsele i-Müllerian, kuvamile ukuba nemibuzo eminingi engqondweni yakho. Ngaleso sikhathi, ngaphandle kokugodla lutho, buza udokotela wakho le mibuzo.
- Ingabe lesi simo sizothinta ukuzala kwami (ikhono lami lokuba nabantwana)?
- Ingabe lokhu kuzothinta ama-hormone ami?
- Yiziphi izindlela zokwelapha lokhu? Ingabe ukuhlinzwa kuyadingeka?
- Ingabe ukuthomba kwami kanye nokuya esikhathini kwami kuzokwenzeka ngendlela evamile?
Udokotela wakho uzokunikeza izimpendulo ezicacile kuyo yonke le mibuzo futhi akunikeze isiqondiso osidingayo.
Ingabe lezi zinhlobo zamaphutha zingavinjelwa ngesikhathi sokukhulelwa?
Lena inkinga abantu abaningi abanayo. Uma sikhuluma iqiniso, ayikho indlela yokuvimbela ngokuphelele ukukhubazeka kwe-Müllerian duct.Ngoba lokhu kuvame ukubangelwa yizimbangela zofuzo noma iphutha elingahleliwe ngesikhathi sokukhula kombungu.
Kodwa, lokho akusho ukuthi akukho esingakwenza. Njengomama okhulelwe, ungalandela indlela yokuphila enempilo ukuze unciphise ingozi yokuzalwa ukhubazekile . Lokhu kubalulekile hhayi kuphela kulezi zinhlobo zokukhubazeka, kodwa nasempilweni iyonke yengane yakho.
- Gwema izidakamizwa ezingekho emthethweni kanye nensangu ngokuphelele.
- Gwema ukubhema notshwala ngokuphelele. Lokhu kuyingozi kakhulu embungwini.
- Qiniseka ukuthi uthola iseluleko esifanele sezokwelapha kanye nokunakekelwa kwangaphambi kokubeletha ngesikhathi sokukhulelwa.
- Uma unezifo ezingamahlalakhona njengesifo sikashukela noma umfutho wegazi ophakeme, zilawule kahle ngaphambi kokukhulelwa.
- Thatha amavithamini aqukethe i-folic acid njengoba nje kunconywe udokotela wakho.
- Gcina isisindo esinempilo.
- Yidla ukudla okunempilo futhi uvivinye umzimba nsuku zonke.
Ngalezi zinto ezilula, ungakha indawo engcono kakhulu yokuba ingane yakho engakazalwa ikhule kahle.
Umlayezo Wokuya Nawe Ekhaya
- Amapayipi e-Müllerian ayisimiso semigudu eyakheka ngesikhathi sokukhulelwa futhi ayisisekelo ekuthuthukisweni kwezitho zokuzala zowesifazane, njengesibeletho namapayipi e-fallopian.
- Lezi ziphambeko zokukhula zikhona lapho kuzalwa futhi zingase zingabonwa kuze kube yilapho sezikhulile noma lapho kulindeleke ukuba izingane zibe khona.
- Lezi ziphambeko azivamile, futhi eziningi zazo zinezindlela zokwelapha kanye nokuphatha.
- Uma unemibuzo noma ukungabaza ngalokhu, kubaluleke kakhulu ukukhuluma ngokukhululekile nodokotela wakho ngakho futhi uthole iseluleko esifanele.
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