Ingabe amathambo akho abuthakathaka futhi abuhlungu? Ake sifunde ngalokhu (Osteitis Fibrosa Cystica - OFC)!

Ingabe ngezinye izikhathi uzizwa ubuhlungu emzimbeni wakho, ikakhulukazi emathanjeni akho? Noma uzizwa sengathi amathambo akho ayaphuka ngisho nento encane? Mhlawumbe kukhona isimo ngemuva kwalezi zinto esingakhulumi kakhulu ngaso, kodwa kubalulekile ukusazi. Esinye isimo esinjalo yi-`(Osteitis Fibrosa Cystica - OFC)`. Nakuba leli gama lingase libonakale liyinkimbinkimbi kancane, ake silichaze kalula.

Kuyini i-Osteitis Fibrosa Cystica (OFC)?

Kalula nje, `(Osteitis Fibrosa Cystica - OFC)` yisifo esingavamile esithinta amathambo ethu. Sihlobene ngqo nezindlala ze-parathyroid emzimbeni wethu. Uke wezwa ngendlala ye-thyroid. Ngemuva kwayo kukhona lezi zindlala ezine ze-parathyroid. Lezi zindlala zikhiqiza i-hormone ye-parathyroid (`Parathyroid Hormone - PTH`) .

Le hormone `(PTH)` ibalulekile ekugcineni amathambo ethu eqinile futhi enempilo. Iphinde isize ekulawuleni izinga le-calcium egazini. Kodwa, cabanga, kwenzekani uma le hormone `(PTH)` ikhiqizwa kakhulu, okungukuthi, kakhulu? Yilapho inkinga iqala khona. Ngenxa yalokho `(PTH)` okweqile, esikhundleni sokuqinisa amathambo, kancane kancane aqala ukuba buthaka . Ngokuhamba kwesikhathi, ukuma kwamathambo kungashintsha, futhi izinto ezifana nezimbobo (njengezimila ezigcwele amanzi) nazo zingakheka ngaphakathi.

Lokhu kunqwabelana kwe-PTH kungabangela ukwanda kwamazinga e-calcium egazini, okuholela ekwakhekeni kwamatshe ezinso, umfutho wegazi ophakeme (umfutho wegazi ophakeme), kanye nokwehluleka kwenhliziyo.

Lesi simo sibizwa ngokuthi `(OFC)` ngamanye amagama amaningana. Kungenzeka ukuthi uke wezwa la magama:

• ``Isifo sethambo sikaVon Recklinghausen''
• `I-Osteitis fibrosa`
• `I-Cystica ejwayelekile`
• `I-Osteodystrophia fibrosa`
• Isimila esinsundu sethambo . Ungakhathazeki ngaleli gama. Nakuba lithi `(Isimila)`, alisho ukuthi `Umdlavuza`. Leli gama lisetshenziswa ngoba abantu abane `(OFC)` banamabala ansundu avela ngenxa yokopha kanye nezicubu ezine-fibrous emathanjeni abo. Kodwa empeleni akulona `(Isimila)` esinomdlavuza.

Amagama athi "(Osteitis Fibrosa Cystica)" asho okuthile okufana 'nokuncibilika kwamathambo nokwakheka kwama-cyst'. Ngakho-ke, lapho izinga le-`(PTH)` likhuphuka, amathambo angonakala nganoma yisiphi isikhathi. Kodwa-ke, uma lesi simo esibizwa ngokuthi `(Hyperparathyroidism)` (okungukuthi ukukhiqizwa ngokweqile kwe-`(PTH)`) kuqashelwa futhi kwelashwe kusenesikhathi, isimo se-`(OFC)` singelashwa noma sivinjelwe ukuthi singabi khona.

Kuvamile kangakanani lesi simo (se-OFC)?

Manje ungase uzibuze ukuthi lesi sifo sivame kangakanani. Eqinisweni, asivamile emazweni anezempilo ezinhle . Isibonelo, ngisho nase-United States, abantu abangaphansi kuka-5% abane-hyperparathyroidism bathola i-OFC. Sivame ukubonakala kubantu abane-hyperparathyroidism enzima abangazange belashwe isikhathi eside.

Kodwa esikhathini esidlule, lokhu kwakuvame kakhulu. Eminyakeni engaba amashumi amahlanu edlule, cishe abantu abangu-69% abane-"Hyperparathyroidism" babenalesi sifo samathambo. Kodwa ngokuthuthuka kwesayensi yezokwelapha, ikakhulukazi ngokufika "kokuhlolwa kwegazi okuvamile", lezi zimo ziye zakwazi ukutholakala nokwelashwa ngokushesha. Akuyona into enhle leyo?

Ziyini izimpawu zalesi simo (i-OFC)?

Kulungile, manje ake sibone ukuthi yiziphi izimpawu ezingase zivele kulesi simo `(Osteitis Fibrosa Cystica)`.

Izimpawu eziyinhloko yilezi:

• Ubuhlungu bamathambo . Lena yinto yokuqala abantu abaningi abayizwayo. Ngezinye izikhathi, kungaba buhlungu ngisho nokuthinta ithambo.
• Ukuphuka kwamathambo . Amathambo, ikakhulukazi lawo asezingalweni, emilenzeni, noma emgogodleni, angaphuka kalula. Ngisho nokuwa okuncane kungaphula ithambo.

Ekuqaleni kwalesi simo, lezi zimpawu ezilandelayo zingase zivele (lezi zingase zibe izimpawu ze-"Hyperparathyroidism"):

• Ukuzizwa ukhathele ngaso sonke isikhathi (`Ukukhathala`).
• Ubuthakathaka.
• Isicanucanu nokuhlanza.
• Ukuqunjelwa.
• Ukuchama okuningi kunokujwayelekile (`i-Polyuria`). Lokhu kusho ukuthi kufanele uye endlini yangasese kaningi.

Uma unalezi zimpawu, ungazinqumeli wedwa ukuthi, "O, lokhu `(OFC)'." Ngoba lezi zimpawu zingaba khona nakwezinye izifo. Kodwa kubaluleke kakhulu ukuzazi lezi bese utshela udokotela.

Yiziphi izimbangela ze-(OFC)?

Yini ebangela i-Osteitis Fibrosa Cystica? Njengoba ngishilo ekuqaleni, imbangela eyinhloko yalokhu i-Hyperparathyroidism engalashwa . Okusho ukuthi, izindlala zethu ze-Parathyroid zikhiqiza i-PTH eningi kakhulu. Lokhu kungenzeka ngezindlela ezimbili eziyinhloko:

1. I-Hyperparathyroidism Eyinhloko: Lokhu kubangelwa inkinga ngezindlala zakho ze-parathyroid. Lezi zindlala zingaba nomdlavuza (umdlavuza) noma zibe nokukhula okungenawo umdlavuza (njenge-adenoma) okubangela ukuthi zikhiqize i-PTH eningi kakhulu. Noma zonke izindlala ezine zingase zande (hyperplasia) futhi zikhiqize i-hormone eningi kakhulu.

2. I-Secondary Hyperparathyroidism: Lokhu kwenzeka ngenxa yesinye isimo sempilo. Isibonelo, uma umuntu enesifo sezinso esingamahlalakhona, ibhalansi ye-calcium ne-vitamin D emzimbeni wakhe iyaphazamiseka. Ngemuva kwalokho, ngenxa yalokho, izindlala ze-parathyroid ziqala ukukhiqiza i-PTH eyengeziwe. Futhi, uma kunokuntuleka okukhulu kwe-vitamin D, izinga le-calcium egazini liphansi, ngakho izindlala ze-parathyroid zisebenza kanzima ukwandisa izinga le-calcium. Ngaleso sikhathi, i-hormone ye-PTH nayo iyakhula, futhi ngokuhamba kwesikhathi, i-Osteitis Fibrosa Cystica ingakhula.

Cabanga nje, u-anti wethu uKamala ubelokhu ehlushwa izinkinga zezinso isikhathi eside. Akazange athathe umuthi ofanele. Ngemva kwesikhashana, izindlala zakhe ze-`(Parathyroid)`, ezazilwela ukulawula i-calcium emzimbeni wakhe, zaqala ukukhiqiza i-`(PTH)` eningi kunalokho okufanele. Ekugcineni, u-anti uKamala waba ne-`(OFC)` kanye nobuhlungu bamathambo. Uyakuqonda ukuxhumana?

Yiziphi izinkinga ezingaba khona ze-(OFC)?

Izinkinga eziyinhloko ze-hyperparathyroidism engalashwanga kanye ne-OFC zihlobene namathambo. Lokhu kusho ubuhlungu, ukukhubazeka kwamathambo (izinguquko esimweni), kanye nokuphuka kalula . Lezi yizinto ezibonakala ngokushesha. Umuntu angase alahlekelwe ngisho nokuphakama.

Nokho, ngaphezu kwalokhu, kungase kube nezinye izinkinga. Lezi yizi:

• Ukwakheka kwamatshe ezinso.
• Ukwehluleka kwezinso.
• Amandla aphansi, ukukhathala okuqhubekayo.
• Ubuhlungu besisu.
• Izinkinga zengqondo ezifana nokucindezeleka.
• Izinkinga zenkumbulo nokunaka.

Bheka ukuthi inkinga eqala endaweni eyodwa ingahamba ibanga elingakanani. Inkinga ohlelweni olulodwa lomzimba wethu ingathinta nezinye izinhlelo. Yingakho ukuxilongwa kusenesikhathi kanye nokwelashwa kubalulekile.

Itholakala kanjani i-OFC?

Kulungile, manje udokotela usithola kanjani lesi simo `(Osteitis Fibrosa Cystica)`?

Okokuqala, udokotela wakho uzothatha umlando ophelele wempilo yakho . Uzokubuza ukuthi usunesikhathi esingakanani unalezi zimpawu, ukuthi unezinye izimo zezokwelapha (njengesifo sezinso) ezingathinta amazinga akho e-PTH, nokuthi imiphi imithi oyiphuzayo. Ngemuva kwalokho, bazokwenza ukuhlolwa ngokomzimba ukuze bahlole ubuhlungu bamathambo, ukuthamba, noma ukukhubazeka.

Ukuqinisekisa lesi sifo, odokotela bangase basebenzise izivivinyo ezifana nalezi:

• Ukuhlolwa kwegazi: Lokhu kuhlola ukungalingani kwama-hormone namaminerali. Ngokukhethekile, kuhlola amazinga e-parathyroid hormone (PTH), amazinga e-calcium, amazinga e-phosphorus, amazinga e-vitamin D, kanye ne-alkaline phosphatase (i-enzyme ekhishwa emathanjeni). Ku-OFC, amazinga e-PTH kanye ne-alkaline phosphatase angaba phezulu kakhulu.
• Ukuhlolwa komchamo: Ungahlola futhi inani le-calcium emchameni wakho.
• Ukuhlolwa kwezithombe:
• Ama-X-ray: Lokhu kungabonisa ukuthi amathambo mancane kangakanani, izinto ezifana nama-cysts, nokuthi ngabe kukhona yini ukuqhekeka okuncane kakhulu (ama-microfractures) noma izinguquko eziphawulekayo emathanjeni (njengokudonswa kwe-subperiosteal).
• Ama-CT Scan (`CT - Computed Tomography scans`) noma ama-MRI Scan (`MRI - Magnetic Resonance Imaging scans`): Lawa abonisa isimo samathambo ngokuningiliziwe kune-X-ray.

Yiziphi izindlela zokwelapha (i-OFC)?

Kulungile, manje ake sixoxe ngokwelashwa kwe-`(Osteitis Fibrosa Cystica)`. Ukwelashwa kuncike ohlotsheni kanye nobukhali be-`(Hyperparathyroidism)` ebangele i-`(OFC)`.

• Uma i-primary hyperparathyroidism ibangelwa yi:
• Ezimweni eziningi, uma imbangela yalesi simo `(OFC)` kungukungasebenzi kahle kwendlala `(Parathyroid)` (njengesimila), ukwelashwa okujwayelekile ukususa indlala ngokuhlinzwa noma ingxenye yendlala (`Parathyroidectomy`) . Lokhu kuhlinzwa kungamisa ukuncipha kwamathambo futhi kubuyisele omunye umonakalo wamathambo osuvele wenzeke (`remineralization`). Ngokuvamile, sinezindlala ezine `(Parathyroid)`. Ngakho-ke, lapho indlala enenkinga isuswa, izindlala ezisele zingakhiqiza i-hormone `(PTH)` edingwa ngumzimba.

• Kulabo abangakwazi ukuhlinzwa noma abane-hyperparathyroidism yesibili:
• Ukwelapha imbangela eyinhloko: Isibonelo, uma imbangela iwukuntuleka kwe-vitamin D, kunikezwa izithasiselo ze-vitamin D. Uma kuyisifo sezinso, kwelashwa ngendlela efanele.
• I-Calcimimetics: Le mithi ilingisa i-calcium egazini lakho. "Ikhohlisa" i-parathyroid gland yakho ukuthi ikhiqize i-PTH encane. I-Cinacalcet ingenye yemithi enjalo.
• Ama-Bisphosphonates: Le mithi isebenza ngokunciphisa izinga lokulahlekelwa amathambo. Ngokuvamile inikezwa abantu abane-osteoporosis. Kodwa-ke, ingaba usizo futhi esikhathini esifushane kubantu abane-OFC, ikakhulukazi ukuqinisa amathambo ngaphambi kokuhlinzwa.
• I-Vitamin D kanye nezithasiselo ze-calcium: Lezi zinikezwa uma kudingeka. Kodwa-ke, uma izinga le-calcium egazini liphezulu, izithasiselo ze-calcium azinikezwa.

Iyini inhloso yesimo (se-OFC)?

Liyini ithemba lalesi simo `(OFC)`? Eqinisweni, ngokuphathwa nokwelashwa okufanele, imiphumela emihle ingatholakala . Ukwelashwa kungamisa ukuncipha kwamathambo futhi kuqinise amathambo (`kuvuselele kabusha`). Amathambo aphukile angaphola futhi anciphise ubuhlungu. Kodwa-ke, uma amathambo ekhubazekile kakhulu, angase angalulami ngokugcwele.

Ingabe (i-OFC) ingavinjelwa?

Kungenzeka yini ukuvimbela ukwenzeka kwalesi simo `(Osteitis Fibrosa Cystica)`? Yebo, ngezinga elithile kungenzeka. Into eyinhloko ukuqaphela nokwelapha lesi simo `(Hyperparathyroidism)` kusenesikhathi.

• Kubaluleke kakhulu ukuhlolwa kwegazi njalo , ikakhulukazi uma unezici eziyingozi njengesifo sezinso. Lokhu kuzosiza ekutholeni noma yiziphi izinguquko emazingeni akho e-calcium ne-PTH ngaphambi kokuba kubangele umonakalo omkhulu.
• Futhi, khuluma nodokotela wakho futhi ugcine amazinga e-calcium ne-vitamin D amahle.Yenza okudingeka ukwenze. Isibonelo, uma uhlala endaweni lapho ukukhanya kwelanga okuncane khona ebusika, kungadingeka ukuthi uphuze izithasiselo zevithamini D. Udokotela wakho uzokutshela nokuthi ungazithola kanjani izakhamzimba ozidingayo ekudleni okudlayo.

Khumbula, lapho isimo `(Hyperparathyroidism)` sisheshe siqashelwe futhi selashwe, kulapho amathuba okuba siqale `(Osteitis Fibrosa Cystica)` mancane khona.

Kufanele ngimbone nini udokotela?

Uma unezinhlungu emathanjeni, ubuhlungu, noma ithambo elizwakala sengathi lizophuka , bona udokotela ngokushesha. Futhi, uma unezinye zezimpawu zokuqala ze-hyperparathyroidism (njengokukhathala, isicanucanu, kanye nokuchama njalo) engizikhulumile ekuqaleni, tshela udokotela wakho ngazo. Uma usuvele une-hyperparathyroidism, kungumqondo omuhle ukuthi igazi lakho lihlolwe njalo ukuze kuhlolwe amazinga akho e-calcium kanye ne-PTH, njengoba udokotela wakho encoma.

Yimiphi imibuzo okufanele ngiyibuze udokotela wami?

Uma kutholakale ukuthi une-`(Osteitis Fibrosa Cystica)`, kungaba usizo ukubuza udokotela wakho le mibuzo:

• Isimo sami sibi kangakanani?
• Yiziphi izindlela zokwelapha enginazo? Yiziphi izinzuzo kanye nokungalungi kwalokhu ngakunye?
• Kulungile yini ukuthi ngithathe izithasiselo? Uhlobo luni?
• Ingabe ngizodinga ukuhlinzwa? Uma kunjalo, yini engingayilindela ngemva kwalokho?
• Yiziphi izinguquko zokudla engingazithatha ezizongisiza?
• Lesi simo sizoyithinta kanjani impilo yami yansuku zonke?

Ekugcineni, amaphuzu ambalwa abalulekile

Ngakho-ke, kufanele ngikutshele lokhu. Amathambo abuthakathaka kanye nobuhlungu kungaba nomthelela omkhulu empilweni yethu yansuku zonke. Uma amathambo akho ephuka kalula, ungase uzizwe sengathi ungayeki eminye imisebenzi. Uma unezimpawu ezifana nokukhathala, ubuthakathaka, isicanucanu, kanye nokuchama njalo, kungaba "i-Hyperparathyroidism" noma inkinga yayo "i-OFC".

Uma unezinye zalezi zimpawu, sicela ubonane nodokotela ngokushesha. Uma usheshe uqaphele futhi welaphe lesi sifo, kulapho umonakalo ongawenza emathanjeni akho uncipha khona. Impilo yakho ibaluleke kakhulu kuwe. Ngakho-ke yinakekele.

I- Osteitis Fibrosa Cystica, i-OFC, Isifo Samathambo, i-Parathyroid, i-PTH Hormone, i-Hyperparathyroidism, Ubuhlungu Bamathambo