Ukuphila nokucindezeleka, isimo esibizwa ngokuthi ukucindezeleka, kungaba nzima kakhulu ngezinye izikhathi, akunjalo? Uma uzizwa sengathi unesithukuthezi ngempilo futhi ungenasithakazelo kunoma yini, kungenzeka ukuthi uke wacabanga, "Asikho yini isisombululo salokhu?" Ama-Selegiline Patches angenye yezindlela zokwelapha ezingakusiza ngezikhathi ezinjalo. Ake sixoxe ngalokhu ngokuningiliziwe namuhla, njengokukhuluma nomngane.
Uhlobo luni lomuthi? I-Selegiline...
Kalula nje, i-Selegiline umuthi osetshenziselwa ukwelapha ukucindezeleka. Iza ngesimo se-patch oyisebenzisa esikhumbeni. Kungenzeka ukuthi uyibonile ngaphansi kwegama lomkhiqizo elithi `EMSAM`.
Lo muthi ungoweqembu lemithi ebizwa ngokuthi i-`MAOI` (i-Monoamine Oxidase Inhibitors). Cabanga ngakho, kunezinhlobo ezahlukene zamakhemikhali ebuchosheni bethu ezisiza ukulawula imizwa yethu. Elinye lamakhemikhali anjalo yi-dopamine. I-Dopamine iyikhemikhali ehilelekile ezintweni ezifana nenjabulo, inhlalakahle, kanye nokunaka ezingqondweni zethu. Lokho okwenziwa yilo muthi we-Selegiline kusiza ukugcina amazinga e-dopamine ebuchosheni elinganiselayo. Ngemuva kwalokho, okunye ukungakhululeki okubangelwa ukucindezeleka kungancishiswa.
Odokotela ngezinye izikhathi bangase bakunike lo muthi kwezinye izimo, ngakho-ke uma uneminye imibuzo mayelana nalokhu, kungcono ukubuza udokotela wakho noma usokhemisi.
Yini okufanele ngiyitshele udokotela ngaphambi kokusebenzisa lo muthi?
Ngaphambi kokuthi uqale ukusebenzisa i-Selegiline Patches, kunezinto ezimbalwa okufanele uzitshele udokotela wakho. Ngoba akuyona yonke imithi efanayo kuwo wonke umuntu. Uma unezinye zezimo ezilandelayo, yazisa udokotela wakho:
- Isifo se-Bipolar: Uma unesifo se-bipolar.
- Umfutho wegazi ophezulu: Uma unomfutho wegazi ophezulu, okungukuthi, uma umfutho wegazi wakho uphakeme.
- Ukusebenzisa utshwala: Uma uphuza njalo.
- Isifo sesibindi: Uma unesifo sesibindi.
- I-Pheochromocytoma: Lesi isimila esakheka ezindlaleni ze-adrenal. Uma unalesi simo.
- Izimo zesikhumba noma ukuzwela: Uma unesifo sesikhumba noma isikhumba sakho sizwela kakhulu.
- Imicabango yokuzibulala: Uma uke waba nemicabango noma amacebo okuzibulala, noma uma othile emndenini wakho eke wazama ukuzibulala. Lokhu kubaluleke kakhulu.
- Ukungezwani komzimba: Uma une-allergy ku-selegiline, eminye imithi, ukudla, udayi, noma izithasiselo.
- Ukukhulelwa: Uma ukhulelwe noma uzama ukukhulelwa.
- Uma ungumama oncelisayo: Uma ungumama oncelisayo ingane.
Ngokutshela udokotela wakho ngalezi zinto, angakunikeza iseluleko esiqondile sokuthi lo muthi ukulungele yini noma cha, nokuthi ungawusebenzisa kanjani ngokuphephile.
Ngilisebenzisa kanjani kahle leli patch?
Lo muthi ungowokusetshenziswa kwangaphandle kuphela, ngakho-ke landela imiyalelo eselebula likadokotela oyinikezwe ngudokotela wakho.
Nansi indlela yokusebenzisa i-patch kalula:
1. Ukususa isiqephu: Susa isiqephu ngokudabula isikhwama esincane esiqukethe isiqephu usebenzisa izimbobo ezinhlangothini. Ungasebenzisi isikele.
2. Indawo yokufaka: I-patch kufanele ifakwe endaweni ehlanzekile, eyomile, nebushelelezi yesikhumba . Ngokuvamile, umhlane ongaphezulu, isifuba esiphezulu, amathanga aphezulu, noma ingemuva kwezingalo ezingaphezulu yizindawo ezifanele lokhu.
3. Izindawo ezingahambisani: Ungafaki i-patch ezindaweni ezinezilonda, isikhumba esicasukile, izibazi, noma isikhumba esinamaqhubu.
4. Sebenzisa i-patch eyodwa ngesikhathi: Ungasebenzisi i-patch engaphezu kweyodwa ngesikhathi.
5. Ungasiki: Ungasiki noma uhlukanise isichibi.
6. Ukunamathela okuhle: Hlola ukuthi i-patch inamathele kahle esikhumbeni. Ikakhulukazi imiphetho kufanele inamathele kahle.
7. Ukususa endala: Ngaphambi kokufaka i-patch entsha, qiniseka ukuthi uyayisusa i-patch endala.
8. Ukushintsha indawo: Isikhathi ngasinye lapho ufaka i-patch entsha, ungayinamathisi endaweni efanayo neyedlule, kodwa uyinamathise endaweni ehlukile, njengasemhlane ongaphezulu, esifubeni esingaphezulu, ethangeni elingaphezulu, noma ngemuva kwengalo engenhla. Unganamathisi endaweni efanayo ngokuphindaphindiwe.
9. Ungasebenzisi okungaphezu kwalokho okunqunywe udokotela, futhi awuyeki ukukuthatha ngaphambi kwesikhathi esinqunyiwe. Uma uyeka , yenza lokho kuphela njengoba udokotela wakho ekuyalile.
Uma uthola lo muthi ekhemisi, uzothola nencwajana yemiyalelo ekhethekile (`MedGuide`). Funda leli pheshana ngokucophelela njalo uma uthola umuthi, futhi njalo uma uthola ukugcwalisa kabusha. Kubaluleke kakhulu.
Ingabe lo muthi ufanelekile ezinganeni?
Lo muthi awuvunyelwe ukusetshenziswa ezinganeni. Ikakhulukazi ungawuniki izingane ezingaphansi kweminyaka eyi-12 ubudala. Uma ingane yakho idinga lolu hlobo lokwelashwa, khuluma nodokotela wezingane ngakho.
Kwenzekani uma uthatha kakhulu? ('Umthamo oweqile')
Uma ucabanga ukuthi uphuze kakhulu lo muthi, noma uma othile ewuphuze ngephutha, shayela isikhungo sokulawula ubuthi noma igumbi lezimo eziphuthumayo eliseduze ngokushesha.
Lomuthi ungowakho kuphela!
Lo muthi onikezwe wena kuphela. Ngakho-ke, ungawabelani nabanye.
Wenzani uma uphuthelwa isikhathi sakho sokuya emtholampilo?
Uma uphuthelwa yi-patch yakho ehleliwe, yifake ngokushesha nje lapho ukhumbula. Kodwa uma sekuyisikhathi se-patch yakho elandelayo, ungafaki entsha. Faka i-patch elandelayo kuphela ngesikhathi esihleliwe. Ungalokothi ufake ama-patch amabili ngesikhathi esisodwa noma uthathe umthamo owengeziwe.
Yikuphi okunye ukusebenzisana okungenzeka nalomuthi?
Leli iphuzu elibaluleke kakhulu. I-Selegiline umuthi ongasebenzisana neminye imithi kanye nokudla okuthile. Ngakho-ke kudingeka uqaphele kakhulu ngalokhu.
I-Selegiline akufanele isetshenziswe kanye nemithi elandelayo:
- I-Atomoxetine
- I-Carbamazepine
- I-Cyclobenzaprine
- I-Dextromethorphan - ingase ibe khona kwezinye iziraphu zokukhwehlela.
- Eminye imithi ye-MAOI: Izibonelo zifaka phakathi iMarplan, iNardil, kanye neParnate.
- Ezinye izindlela zokuqeda ubuhlungu zifaka: i-meperidine, i-tramadol, i-methadone, kanye ne-pentazocine.
- Kuneminye imithi eminingi yokucindezeleka.
- Eminye imithi equkethe i-selegiline: Isibonelo, imithi ebizwa ngokuthi i-`Eldepryl` kanye ne-`Zelapar`.
- I-Rasagiline
- I-Safinamide
- Imithi evuselelayo yokuphazamiseka kokunaka.
- I-St. John's Wort - Lona umuthi wezitshalo osetshenziswa abanye abantu.
- I-Viloxazine
Lo muthi ungase futhi uhlangane nalokhu okulandelayo:
- Utshwala
- I-Buspirone
- I-Ephedrine
- I-Epinephrine noma i-racepinephrine
- Ama-decongestant: njenge-phenylephrine kanye ne-pseudoephedrine.
- I-Norepinephrine
- Imithi yokuvuselela esetshenziselwa ukwehlisa isisindo noma ukuhlala uphapheme.
Lolu hlu alubandakanyi konke. Ngakho-ke, tshela udokotela wakho ngayo yonke imithi oyithathayo (eyalelwe udokotela, ethengiswa ngaphandle kwemithi kadokotela, imithi yamakhambi, amavithamini, izithasiselo zokudla). Futhi, tshela udokotela wakho uma ubhema, uphuza utshwala, noma usebenzisa izidakamizwa ezingekho emthethweni. Ezinye zalezi zinto zingathintana nemithi yakho.
Yiziphi izinto okufanele uziqaphele uma usebenzisa lo muthi?
Kubaluleke kakhulu ukukhuluma nodokotela wakho ngempilo yakho futhi uhlolwe njalo ngenkathi uthatha lo muthi. Uma izimpawu zakho zingathuthuki noma zibonakala ziba zimbi kakhulu, tshela udokotela wakho.
Kungathatha amasonto ambalwa ukubona umphumela ophelele walo muthi. Ngakho-ke, kubalulekile ukuqhubeka nokuthatha umuthi njengoba uyalelwe udokotela wakho. Ungayeki ukuthatha umuthi ngokuzumayo ngaphandle kweseluleko sikadokotela. Ukwenza kanjalo kungabangela ukusabela okubi kakhulu. Udokotela wakho uzokutshela ukuthi umuthi ongakanani okufanele uwuthathe.
Qaphela imicabango yokuzibulala!
Iziguli nemindeni yazo kufanele ziqaphele imicabango emisha noma eba mibi yokuzibulala noma ukucindezeleka. Futhi, qaphela izinguquko ezisheshayo zemizwa - isibonelo, ukuzizwa ungakhululekile, ukhathazekile, ucasukile, uthukuthele kalula, ulaka, ungakhathazeki kakhulu, ujabule kakhulu, noma unenkinga yokulala - futhi ukhulume nodokotela wakho ngokushesha uma lokhu kwenzeka, ikakhulukazi ekuqaleni kokwelashwa noma ngemuva kokushintsha umthamo wakho.
Qaphela ukudla okuqukethe i-tyramine!
Uma udokotela wakho enyusa umthamo walo muthi ube ngaphezu kwama-milligram angu-6 (6 mg) ngosuku, kufanele futhi uqaphele ukudla okuqukethe ikhemikhali ebizwa ngokuthi i-tyramine. Lo muthi ungasabela ekudleni okunjalo futhi ubangele ikhanda elibuhlungu, ukwanda komfutho wegazi ngokuzumayo, noma ukushaya kwenhliziyo okungajwayelekile .
Ngisho nangemva kokuba udokotela wakho ehlise umthamo wakho emuva kuma-milligram angu-6 (`6 mg`) ngosuku, noma ngemva kokuyeka ukuthatha umthamo wama-milligram angu-9 noma angu-12 (`12 mg`) ngosuku, kufanele ugweme ukudla neziphuzo ezine-tyramine eningi amasonto amabili . Kodwa-ke, uma uqala futhi uqhubeka nokuthatha umthamo wama-mg angu-6, kungase kungadingeki wenze noma yiziphi izinguquko ezinkulu ekudleni kwakho. (Ungabuza udokotela wakho noma isazi sokudla ukuze uthole ulwazi olwengeziwe ngalokhu.)
Ezinye izinto okufanele uzicabangele:
- Ukozela/Isiyezi: Ungase uzizwe ulele noma unesiyezi. Ngakho-ke, gwema ukushayela, ukusebenzisa imishini, noma ukwenza noma yini edinga ukugxilisa ingqondo uze wazi ukuthi lo muthi uthinta kanjani wena. Ungami noma uhlale ngokuzumayo, ikakhulukazi uma usukhulile. Ukwenza kanjalo kunganciphisa ingozi yokuba nesiyezi nokuwa.
- Utshwala: Utshwala bungaphazamisa ukusebenza kahle kwalomuthi. Ngakho-ke, gwema ukuphuza utshwala.
- Umlomo owomile: Umlomo wakho ungase uzizwe womile. Ukuhlafuna itshungama engenashukela, ukumunca i-toffee engenashukela, nokuphuza amanzi amaningi kungasiza ekunciphiseni lokhu. Uma le nkinga iqhubeka noma iba nzima, khuluma nodokotela wakho.
- Eminye imithi:Ungathathi noma yimuphi umuthi wokukhwehlela, umkhuhlane, noma ukungezwani komzimba ngaphandle kokubonisana nodokotela wakho. Futhi, ungathathi noma yimuphi umuthi wokwehlisa isisindo ngaphandle kweseluleko sikadokotela. Izithako kweminye yale mithi zingandisa imiphumela emibi.
- Isifo Sikashukela: Lo muthi ungathinta amazinga kashukela egazini. Uma unesifo sikashukela (i-Diabetes Mellitus), khuluma nodokotela wakho ngaphambi kokushintsha ukudla kwakho noma umthamo womuthi wakho wesifo sikashukela.
- Ukuhlinzwa: Uma unezinqubo zezokwelapha noma zamazinyo, tshela ithimba lezokwelapha ukuthi uthatha lo muthi, njengoba ungase uhlangane neminye imithi esetshenziswa ngesikhathi sokuhlinzwa.
- Isiqephu kanye nokushisa komzimba: Lesi siqephu siyazwela ezinguqukweni ezithile zokushisa komzimba. Lokhu kusho ukuthi uma isikhumba sakho sishisa kakhulu, isiqephu singase simunce umuthi omningi esikhumbeni sakho. Ngakho-ke, uma uba nomkhuhlane, khuluma nodokotela wakho. Futhi, gwema ukugeza emanzini ashisayo kakhulu, ukushawa yilanga, ukusebenzisa amabhavu ashisayo, ama-sauna, ukufudumala isikhumba sakho ngama-hairdryer, ukusebenzisa ama-heating pad, ama-electric blankets, ama-waterbed afudumele, kanye nezibani zokushisa. Futhi, nciphisa ukuzivocavoca okwandisa izinga lokushisa lomzimba wakho ngalesi sikhathi. Lokhu kubaluleke kakhulu ngokushisa ezweni lakithi.
Yimiphi imiphumela emibi engaba khona yalo muthi?
Njengayo yonke imithi, lena ingabangela imiphumela emibi, kodwa akuwona wonke umuntu oyitholayo.
Imiphumela emibi okufanele uyitshele udokotela wakho ngokushesha:
- Ukusabela kokungezwani komzimba: ukuqubuka kwesikhumba, ukulunywa, amaqhubu, ukuvuvukala kobuso, izindebe, ulimi, noma umphimbo.
- Ukwanda okukhulu komfutho wegazi: ikhanda elibuhlungu elibuhlungu ngokuzumayo, isicanucanu, ukuhlanza, ukuqina kwentamo, ukushaya kwenhliziyo okusheshayo noma okungajwayelekile.
- Imicabango yokuzibulala noma yokuzilimaza, isimo sengqondo esibi kakhulu, noma imizwa yokucindezeleka okukhulu.
Imiphumela emibi engavamile ukudinga iseluleko sezokwelapha, kodwa okufanele ibikwe kudokotela wakho uma iqhubeka noma ikhathaza:
- Isiyezi
- Ukozela
- Umlomo owomile
- Ikhanda elibuhlungu
- Ukungakhululeki okufana nokubomvu nokulunywa endaweni lapho kufakwe khona i-patch (Ukucasuka endaweni lapho kufakwe khona)
- Isicanucanu
- Inkinga yokulala
Lolu hlu lungase lungahlanganisi yonke imiphumela emibi. Uma uhlangabezana nanoma yimiphi eminye imiphumela emibi, khuluma nodokotela wakho ngayo. Ungabika futhi imiphumela emibi ku-FDA (Food and Drug Administration) ngokushayela ku-1-800-FDA-1088.
Uwugcina kanjani lo muthi?
- LomuthiGcina kude nezingane nezilwane ezifuywayo.
- Gcina ekamelweni lokushisa (phakathi kwama-degree Celsius angu-20 no-25 / 68 no-77 degrees Fahrenheit).
- Gcina lo muthi esikhwameni sawo sokuvikela kuze kube yilapho usukulungele ukusetshenziswa.
- Ungayisebenzisi imithi ephelelwe yisikhathi, yilahle.
Uyilahla kanjani imithi engasetshenziswanga, ephelelwe yisikhathi?
- Thatha lo muthi uye endaweni "enohlelo lokubuyisela imithi emuva." Ungathola ngezindawo ezinjalo ekhemisi lakho noma emaphoyiseni.
- Uma kungekho ndlela yokuyibuyisela, buza usokhemisi wakho noma udokotela ukuthi ungawulahla kanjani lo muthi ngokuphephile.
Ngemva kokususa isichibi esisetshenzisiwe, hlanganisa izinhlangothi ezinamathelayo ndawonye, usibeke ephaketheni elingenalutho, bese usiphonsa ngokushesha ebhodweni likadoti elinesivalo. Lokhu kuzogcina izingane nezilwane zingangeni endleleni. Bese ugeza izandla zakho kahle.
Umyalezo Wokuya Ekhaya:
Kulungile, ngakho-ke sesikhulume kakhulu ngama-Selegiline Patches, akunjalo? Lesi yi-patch esetshenziswa esikhumbeni futhi isetshenziswa njengokwelapha ukucindezeleka.
- Landela imiyalelo kadokotela wakho ngqo: Sebenzisa umthamo onqunyiwe isikhathi esinqunyiwe, njengoba kuqondiswe udokotela wakho. Ungayeki ukuwuthatha ngokuzumayo.
- Tshela udokotela wakho ngezimo zakho zempilo: Qiniseka ukuthi utshela udokotela wakho nganoma yiziphi ezinye izifo, imithi oyiphuzayo, kanye nokungezwani komzimba onakho.
- Qaphela imiphumela emibi: Qaphela ikakhulukazi imiphumela emibi emibi, njengemicabango yokuzibulala kanye nomfutho wegazi ophakeme. Uma uhlangabezana nanoma yikuphi kwalokhu, tshela udokotela wakho ngokushesha.
- Ukudla neminye imithi: Okunye ukudla (okuqukethe i-'Tyramine') kanye neminye imithi kungase kuhlangane nalesi sici, ngakho-ke qaphela nalokho.
- Faka futhi ugcine i-patch ngendlela efanele: Qaphela ukuthi uyifaka kanjani i-patch, ukuthi uyisusa kanjani endala, nokuthi ushintsha kanjani indawo lapho ufaka khona entsha. Futhi, ungakhohlwa ukugcina umuthi ngendlela efanele.
Khumbula, lesi sihloko senzelwe ulwazi olujwayelekile kuphela. Uma unemibuzo noma ukukhathazeka mayelana nalo muthi, sicela uxoxe ngawo nodokotela wakho, usokhemisi, noma omunye umhlinzeki wezempilo. Sikufisela ukululama okusheshayo!
👩🏽⚕️ Imibuzo eyengeziwe (ama-FAQ)
💬 Ingabe iPhenelzine (Nardil) iyiphilisi lokucindezeleka?
Cha! Lesi akusona isidakamizwa se-SSRI esivamile sengqondo (njenge-Fluoxetine)! Lesi isidakamizwa esidala kakhulu, kodwa esinamandla esivela eqenjini le-'MAOI' esinikezwa njengendlela yokugcina 'yokucindezeleka okukhulu nokuphikelelayo' (ukucindezeleka okumelana nokwelashwa) okungazange kwelashwe yinoma yimiphi imithi emisha. Lesi sidakamizwa sandisa amakhemikhali amaningana 'enjabulo' (i-Serotonin, i-Dopamine, i-Norepinephrine) ebuchosheni ngesikhathi esisodwa, siphilise isiguli ngokushesha.
💬 Kungani abantu abasebenzisa lo muthi (MAOI) kudingeka balandele 'ukudla' okukhethekile?
Lokhu kubaluleke kakhulu! Lo muthi uvimba i-enzyme ephula ikhemikhali ebizwa ngokuthi 'i-Tyramine' emzimbeni wethu. Ngakho-ke uma udla ukudla okufana noshizi, inyama egugile (i-Salami), amasoseji, ama-pickle, utshwala kanye ne-soy sauce ngenkathi uthatha lo muthi, umzimba wakho uzogcwala i-tyramine futhi umfutho wegazi wakho uzokhuphuka ngokuzumayo uze uqhume (i-Hypertensive crisis), i-brain aneurysm/ukuhlaselwa yinhliziyo futhi ungase ufe!
💬 Ngingayisebenzisa yini eminye imithi yokucindezeleka ngalo muthi?
Cha! Lokhu kuyabulala. Uma uthatha i-Phenelzine kanye neminye imithi efana ne-Fluoxetine / i-Sertraline / isiraphu yokukhwehlela, inani le-serotonin ebuchosheni lizokhuphuka liye ezingeni elingabekezeleleki (i-Serotonin syndrome) futhi isiguli sizofa. Ngisho nangemva kokuyeka i-Phenelzine, odokotela ngeke bakuvumele ukuthi uqale noma yimuphi omunye umuthi wokucindezeleka izinsuku ezingu-14 (amasonto amabili)!
I- Selegaline, ukucindezeleka, i-MAOI, i-dopamine, i-patch, impilo yengqondo, imiphumela emibi
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