Wake wezwa ngegama elithi G6PD? Mhlawumbe udokotela ukutshelile ngalo, noma mhlawumbe othile emndenini wakho ukutshelile. Noma mhlawumbe kuyinto entsha ngokuphelele kuwe. Kodwa-ke, ungesabi uma uzwa igama. Ukuntuleka kwe-G6PD kuyisimo esivamile kakhulu sezakhi zofuzo esithinta abantu abangaba yizigidi ezingu-400 emhlabeni jikelele. Kufana noshintsho oluncane emizimbeni yethu kunokuba kube yisifo. Ngakho-ke ake sixoxe ngakho konke kalula nangendlela enobungane namuhla.
Kuyini ngempela ukuntuleka kwe-G6PD?
Kulungile, ake sikubeke kalula lokhu. Igazi lethu liqukethe uhlobo lweseli elibizwa ngokuthi amaseli abomvu egazi . Lawa maseli athwala umoya-mpilo emizimbeni yethu yonke. Kufana nemoto ethwala izimpahla eziya endlini.
Manje, kukhona i-enzyme ekhethekile esiza la maseli abomvu egazi ukuthi ahlale ephilile futhi enamandla. Siyibiza ngokuthi 'i-Glucose-6-Phosphate Dehydrogenase', noma i-G6PD ngamafuphi. Cabanga ngale enzyme njengomvikeli wamangqamuzana abomvu egazi, noma 'ukunikezwa kwamandla' okuwanika amandla. Le enzyme ye-G6PD ivikela amangqamuzana abomvu egazi kwezinye zezinto eziyingozi egazini.
Okwenzeka emzimbeni womuntu onesifo se-G6PD ukuthi i-enzyme ye-G6PD ayikhiqizwa ngobuningi obanele. Noma i-enzyme ekhiqizwayo ayisebenzi kahle. Lokhu kuyifa . Lokho kusho ukuthi ukuzuza lokhu kumama noma kuyihlo, futhi akusona isifo esithathelwanayo.
Ngokuvamile, ukuntuleka kwe-G6PD akuyona inkinga enkulu. Kodwa-ke, uma uphuza imithi ethile, amakhemikhali, noma ukudla okuthile (ikakhulukazi izinhlobo ezithile zobhontshisi), amangqamuzana abomvu egazi aqala ukonakala ngoba lowo mvikeli ulahlekile. Yilokhu esikubiza ngokuthi 'i-hemolytic anemia.' Ake sikubheke kakhudlwana.
Ziyini izimpawu? Sikubona kanjani lokhu?
Into emangalisayo lapha ukuthi abantu abaningi abanesifo sokuntuleka kwe-G6PD ababonisi zimpawu . Baphila impilo ejwayelekile. Inkinga ivela kuphela uma bethola esinye 'sezimbangela' esikhulume ngazo ekuqaleni, okungukuthi, umuthi noma ukudla okungekuhle.
Kodwa-ke, ngezinye izikhathi umntwana angaba ne-jaundice (ukuphuzi kwesikhumba) ngemva kokuzalwa, okuvame ukwelashwa kalula.
Uma umuntu onesifo se-G6PD evezwa yinto eyingozi, angaba nesimo esibizwa ngokuthi 'i-hemolytic anemia.' Kalula nje, lokhu kwenzeka lapho amangqamuzana abomvu ephuka futhi ebhujiswa ngokushesha kunalokho angakwenziwa. Amangqamuzana abomvu egazi yiwo athwala umoya-mpilo emzimbeni wonke. Ngakho-ke lapho ebhujiswa, izitho zomzimba aziwutholi umoya-mpilo eziwudingayo.
Uma lesi simo se-'hemolytic anemia' sivela, singaba sibi kakhulu. Ngakho-ke, kubaluleke kakhulu ukuqaphela lezi zimpawu.
Ithebula elingezansi libala izimpawu ezivamile ze-hemolytic anemia.
| Isibonakaliso | Incazelo |
|---|---|
| Isikhumba esikhanyayo | Isikhumba siyashintsha umbala futhi sibe mhlophe, njengokungathi umzimba awunalo igazi. |
| Ukuphuzi kwesikhumba namehlo (i-Jaundice) | I-Bilirubin, into ekhiqizwa lapho amangqamuzana abomvu egazi ewohloka, ibangela isikhumba kanye namhlophe emehlweni ukuba aphenduke aphuzi. |
| Umchamo omnyama | Umchamo uphenduka onsundu omnyama noma ube nombala we-cola. |
| Imfiva | Ungase uzizwe ushisa ngaphandle kwesizathu. |
| Ukukhathala nobuthakathaka | Ukuzizwa ungenampilo, uphelelwa umoya, futhi ukhathele kakhulu. |
| Ukudideka | Uma ubuchopho bungatholi umoya-mpilo owanele, ungase uzizwe udidekile futhi udidekile. |
| Ukushaya kwenhliziyo | Isilinganiso senhliziyo siyanda. |
Uma lezi zimpawu zinzima futhi ziqhubeka, kufanele ubonane nodokotela ngokushesha . Ngezinye izikhathi kungadingeka uye eMnyangweni Wezimo Eziphuthumayo (ETU) wesibhedlela.Kungase kudingeke futhi kususwe. Kodwa ezimweni eziningi, uma imbangela yalesi simo isisusiwe, izophola ngokwayo zingakapheli amasonto amabili.
Iyini imbangela yalokhu? Ubani onamathuba amaningi okuba nakho?
Njengoba sishilo ngaphambili, ukuntuleka kwe-G6PD kuyisimo esibangelwa ufuzo ngokuphelele . Lokhu kusho ukuthi ukuzuza njengefa kubazali bakho. Ayikho indlela yokukuvimbela.
Kodwa-ke, amanye amaqembu abantu anamathuba amaningi okuthola lesi simo.
- Kwabesilisa (ngaphezu kwabesifazane).
- Kulabo abasemazweni ase-Afrika, e-Asia, eMpumalanga Ephakathi, kanye nasesifundeni saseMedithera.
Uma wazi ukuthi othile emndenini wakho unesifo sokuntuleka kwe-G6PD, kungenzeka ukuthi nawe ungaba naso. Ngakho-ke kuwumqondo omuhle ukukhuluma nodokotela wakho ngakho.
Uthola kanjani ukuthi unesifo se-G6PD?
Kukhona indlela elula kakhulu yokuthola. Lokho kungokwenza ukuhlolwa kwegazi . Udokotela wakho uzoncoma lokhu kuhlolwa ngokusekelwe emlandweni womndeni wakho kanye nokuthi unezimpawu.
Ngokuvamile, ukuhlolwa kokuhlolwa kwenziwa kuqala ukuze kubonakale ukuthi kukhona yini ukuntuleka kwe-G6PD. Uma kukhombisa ukuthi kukhona ukuntuleka, kwenziwa ukuhlolwa okwengeziwe ukuze kubonakale ukuthi kukhulu kangakanani. `Ukuhlolwa kwe-Beutler` kungenye yezivivinyo ezinjalo.
Ngalezi zivivinyo, ungathola ukuthi unesifo se-G6PD yini nokuthi, uma kunjalo, izinga laso lingakanani.
Ungaphila kanjani nokuntuleka kwe-G6PD? Yiziphi izinto okufanele uzigweme?
Lena yingxenye ebaluleke kakhulu. Uma kutholakala ukuthi unesifo sokuntuleka kwe-G6PD, akukho ukwelashwa okukhethekile okudingekayo . Okudingeka ukwenze nje ukugwema 'izinto ezibangela' ukulimaza amangqamuzana akho abomvu egazi futhi ezibangela isimo esibizwa ngokuthi i-hemolytic anemia.
Lokho kusho ukuthi kufanele ugweme ngokuphelele imithi ethile, amakhemikhali, kanye nokudla. Lokhu kubizwa ngokuthi izinto ezibangela 'ukucindezeleka kwe-oxidative'.
Khumbula ithebula elingezansi. Kubaluleke kakhulu ukugcina lezi zinto zingangeni empilweni yakho.
| Izinto okufanele abantu abanesifo se-G6PD bazigweme nakanjani | |
|---|---|
| Uhlobo | Izibonelo |
| Ukudla | Ubhontshisi be-Fava - Lokhu ukudla okubaluleke kakhulu nokuyingozi. Kwamanye amazwe, lokhu kubizwa nangokuthi ubhontshisi obanzi. |
| Imithi | Ezinye izidakamizwa zokuqeda ubuhlungu (isib. i- aspirin eningi) |
| Ama-antibiotic aqukethe i-"Sulfonamides" (isb. ama-Sulfonamides) | |
| Imithi yokulwa nomalaleveva equkethe "i-quine" | |
| Amakhemikhali | I-Naphthalene - Lezi zitholakala kuma-mothball abekwe emakhabetheni. Ngisho nokuphefumula iphunga lawo kuyingozi. |
Okubalulekile: Uma unesifo sokuntuleka kwe-G6PD, kufanele utshele udokotela wakho njalo uma umbona. Ngemuva kwalokho, lapho ekubhalela imithi, uzokhetha imithi ephephile kuwe. Ungalokothi uthathe noma yimuphi umuthi ngaphandle kokubonisana nodokotela kuqala.
Umlayezo Wokuya Nawe Ekhaya
- Ukuntuleka kwe-G6PD akusona isifo okufanele sesatshwe. Kuyisifo sofuzo abantu abaningi emhlabeni abanaso, futhi sidluliselwa ezizukulwaneni ngezizukulwane.
- Abantu abaningi abanazo izimpawu futhi bagula kuphela uma bethola umuthi omubi, ukudla (ikakhulukazi ubhontshisi we-fava), noma amakhemikhali.
- Ukuze uphathe impilo yakho ngempumelelo, udinga ukwazi kahle ukuthi yiziphi izinto ezimbi kuwe futhi uzigweme.
- Uma uhlangabezana nezimpawu ezifana nomkhuhlane, ukukhathala okukhulu, ukuphuzi kwesikhumba, nomchamo omnyama, xhumana nodokotela ngokushesha.
- Khumbuza udokotela wakho njalo uma umbona ukuthi unesifo sokuntuleka kwe-G6PD. Kubaluleke kakhulu ekuphepheni kwakho.
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