So wote nka nso sɛ woabrɛ na woabrɛ wɔ ɔkwan soronko so da mũ nyinaa a ntease biara nnim? So wote nka sɛ wunni ahoɔden? Anaasɛ wo mu duru so retew ka aduan ho akɔnnɔ a ɛrekɔ fam ho? Ɛwom sɛ yɛtaa susuw nneɛma yi ho sɛ ɔbrɛ a ɛfata de, nanso ɛtɔ mmere bi a eyi betumi ayɛ biribi a anibere wom kɛse ho sɛnkyerɛnne. Ɛno ne tebea a yɛreka ho asɛm nnɛ, Addison Yare. Mma ɛnhaw wo, yɛbɛka biribiara ho asɛm wɔ nsɛm a ɛnyɛ den mu.
Sɛ yɛbɛka no tiawa a, dɛn ne Addison Yare no?
Fa no sɛ yɛn nipadua yɛ adwumayɛbea a ɛyɛ den yiye na ɛyɛ nwonwa. Wɔ saa adwumayɛbea yi mu no, nnuru abɔfo kuw bi wɔ hɔ a wɔma biribiara kari pɛ na ɛkɔ so yiye. Yɛfrɛ wɔn
hormone ahorow . Yɛn asaabo atifi pɛɛ no, ntini nketenkete abien wɔ hɔ, yɛfrɛ no
adrenal glands . Ntini nketewa abien yi yɛ nkwaadɔm ahorow pii a ɛho hia ma yɛn asetra. Enti, sɛ biribi nti saa adrenal ntini ahorow yi ntumi nyɛ hormone dodow a wɔhwehwɛ a, ɛno ne nea yɛfrɛ no Addison Yare anaa Primary Adrenal Insufficiency. Eyi yɛ tebea a ɛntaa nsi koraa. Ɛka nnipa bɛyɛ ɔpepem biako biara mu biako. Nanso nea eye sen biara ne sɛ
, sɛ wohu yare no yiye na wofa ayaresa a oduruyɛfo akyerɛ wo no a, wubetumi atra ase sɛnea ɛsɛ a ɔhaw biara nni ho. Ma yensua hormone ahorow abien a ɛho hia sen biara no ho ade.
Hormone ahorow atitiriw abien na ɛso tew wɔ nipadua no mu wɔ Addison yare no mu. 1.
Cortisol: Wɔsan frɛ eyi sɛ ‘adwennwen hormone’. Wɔde saa hormone yi siesie nipadua no ma etumi di adwennwen ho dwuma, sɛ́ ɛyɛ adwene anaa honam fam. Bio nso, ɛboa ma wodi
mogya mmoroso ne sɛnea nipadua no de protein, carbohydrates, ne srade di dwuma no so. 2.
Aldosterone: Saa hormone yi nam yɛn asaabo so na ɛhwɛ nkyene (sodium) ne potassium dodow a ɛwɔ nipadua no mu so. Sɛ wɔanyɛ eyi yiye a, nkyene dodow a ɛwɔ nipadua no mu no so tew na mogya mmoroso fi ase kɔ fam.
Dɛn ne Addison yare no ho sɛnkyerɛnne?
Saa yare yi ho sɛnkyerɛnne da adi nkakrankakra, nkakrankakra paa. Enti, ɛtɔ mmere bi a egye bere ansa na wɔahu yare no. Esiane sɛ saa sɛnkyerɛnne ahorow yi pii te sɛ nyarewa afoforo nti, ɛho hia yiye sɛ wobɛkɔ oduruyɛfo nkyɛn na wahu
yare no pɛpɛɛpɛ .
| Nsɛnkyerɛnne a ɛkyerɛ | Nea ɛrekɔ so no ho nkyerɛkyerɛmu tiawa |
|---|
| Ɔbrɛ a enni sabea ne ntini mu mmerɛwyɛ | Ɔbrɛ a ɛtra so ne nkate a ɛma obi te nka sɛ nkwa nnim mpo a ɔnyɛ hwee. |
| Aduan ho akɔnnɔ a ɛyera na ne mu duru so tew | Aduan ho akɔnnɔ a ɛyera, na ɛma ne mu duru so tew nkakrankakra. |
| Wora a ɛyɛ tuntum (Hyperpigmentation) . | Wora no kɔla a ɛsakra bruu/tuntum wɔ mmeae a owia bɔ ne nea ɛnkɔ so. Wobetumi ahu nsakrae yi titiriw wɔ moma so, nkotodwe, nsateaa, akuru, nsensanee nketenkete, ne anom. |
| Mogya mmoroso a ɛba fam (Hypotension) . | Mogya mmoroso a ɛba fam. Eyi betumi ama obi adwenem ayɛ no naa na watotɔ piti, titiriw bere a wogyina hɔ no. |
| Nkyene ho akɔnnɔ a ɛboro so | Bere a woyi nkyene fi nipadua no mu no, ɔpɛ a obi wɔ sɛ obedi nnuan a nkyene wom bere nyinaa. |
| Nneɛma afoforo a ɛwom | Asikre a ɛba mogya mu (Hypoglycemia), akisikuru, ɔfe, yafunu mu akisikuru, akisikuru, adwennwen a wontumi nnyina adwennwen ano, abufuw, nsu a ɛtɔ, ne nkwaa mu yaw. |
Nea ɛho hia: Nyarewa afoforo nso betumi de saa sɛnkyerɛnne ahorow yi aba. Enti, sɛ wuhyia biribi a ɛte sɛɛ a, hwɛ hu sɛ wobɛkɔ w’abusua oduruyɛfo nkyɛn akɔhwehwɛ afotu.
Dɛn na ɛde Addison yare no ba?
Nea ɛde eyi ba titiriw na ɛtaa ba ne
yare a nipadua no tumi ko tia nyarewa . Sɛ yɛbɛka no tiawa a, yɛn nipadua no ahobammɔ nhyehyɛe (immun system) di mfomso tow hyɛ yɛn ankasa adrenal glands so na ɛsɛe. Eyi na ɛde bɛyɛ 70% ba. Nea ɛka ho no, ebia nneɛma afoforo nso wɔ hɔ a ɛde ba.
- Nyarewa: Nsanyare , .Nyarewa a emu yɛ den a ɛtra hɔ kyɛ te sɛ HIV ne fungal yare bi betumi asɛe adrenal ntini no .
- Kokoram: Kokoram nkwammoaa a efi mmeae afoforo betumi atrɛw akɔ adrenal glands no mu (eyi ho yɛ na koraa).
- Mogya a ɛtɔ wɔ nipadua no mu: Mogya a ɛtɔ wɔ adrenal glands no mu.
- Awosu mu nneɛma: Asiane nso wɔ hɔ sɛ obi benya saa yare yi esiane awosu mu tebea horow bi nti.
- Oprehyɛn: Nneɛma te sɛ oprehyɛn a wɔde yi adrenal glands no fi hɔ.
Ɔkwan bɛn so na oduruyɛfo hu yare yi?
Sɛ wokɔ oduruyɛfo nkyɛn a, obetie wo yare no ho sɛnkyerɛnne no yiye na wahwɛ wo nipadua mu, titiriw ahwehwɛ sɛ wo honam ani kɔla tuntum biara bɛsakra wo honam ani ne wo sẽ. Afei, wɔbɛyɛ nhwehwɛmu ahorow pii de akyerɛ sɛ wɔahu yare no.
- Mogya mu nhwehwɛmu: Eyinom hwɛ sodium (nkyene), potassium, ne cortisol hormone dodow a ɛwɔ nipadua no mu. Wɔ Addison yare no mu no, ebia sodium dodow bɛba fam na potassium dodow nso betumi ayɛ kɛse.
- ACTH stimulation test: Eyi ne sɔhwɛ titiriw a wɔde hu yare no. Wɔ sɔhwɛ yi mu no, wɔde hormone bi a wɔfrɛ no ACTH a efi amemene no mu no ma sɛ aduru a wɔde twitwiw nipadua no mu, na afei wɔkyerɛ cortisol dodow a ɛwɔ mogya no mu. Wɔ obi a ɔwɔ apɔwmuden mu no, cortisol dodow dɔɔso. Nanso, wɔ obi a ɔwɔ Addison yare no mu no, adrenal ntini no ntumi nyɛ adwuma, enti cortisol dodow kɔ so sua.
- Nhwehwɛmu afoforo: Ɛtɔ mmere bi a, wobetumi ayɛ CT scan de ahwɛ sɛ ɔyare mmoawa, kokoram, anaa mogya retu wɔ adrenal glands no mu anaa.
Ayaresa ne sɛnea wɔhwɛ so
Addison yare no yɛ hormone a enni nipadua no mu, na ayaresa no ne sɛ wɔde hormone a enni nipadua no mu bɛma akyi. Eyi yɛ biribi a ɛsɛ sɛ wɔyɛ wɔ nkwa nna nyinaa mu.
- Hydrocortisone aduru: Ɛsɛ sɛ wɔnom eyinom da biara da na ama wɔde asi cortisol hormone ananmu.
- Fludrocortisone aduru: Ɛsɛ sɛ wɔnom eyinom da biara da na ama wɔde asi hormone aldosterone ananmu.
Ade a ɛho hia sen biara ne sɛ wobɛnom dodow a wo duruyɛfo akyerɛ wo no, wɔ bere a ɛfata mu, a worenhwere da koro mpo. Sɛ wopa dodow biako mpo a, ebetumi ayɛ asiane.
Sɛ wowɔ adwennwen te sɛ ɔyare mmoawa, oprehyɛn, anaa akwanhyia a, ebia ɛho behia sɛ wɔma aduru yi dodow a wode di dwuma no kɔ soro. Wo duruyɛfo bɛbɔ wo amanneɛ wɔ eyi ho.
Ɔhaw a ɛyɛ hu sen biara: Addisonian Crisis
Eyi ne
ntɛmpɛ a emu yɛ den na ɛde nkwa to asiane mu sen biara a ebetumi aba wɔ Addison yare no mu.Sɛ nipadua no wɔ adwennwen a emu yɛ den mu (e.g., ɔyare mmoawa a emu yɛ den, akwanhyia, oprehyɛn) a, nipadua no ntumi nnyina ano esiane hormone dodow a ɛba fam nti. Afei sɛnkyerɛnne ahorow no mu yɛ den mpofirim.
Addisonfo ɔhaw bi ho sɛnkyerɛnne: Sɛ saa sɛnkyerɛnne ahorow yi bi ba a, ɛyɛ aduruyɛ mu asɛm a egye ntɛmpɛ. Ɛsɛ sɛ wɔde ɔyarefo no kɔ ayaresabea a ɛbɛn no no Emergency Treatment Unit (ETU) ntɛm ara. Nkrasɛm a Wɔde Kɔ Fie
- Ɛwom sɛ Addison yare no yɛ tebea a ɛkɔ so wɔ nkwa nna nyinaa mu de, nanso sɛ wɔde ayaresa a ɛfata di dwuma a, wobetumi abɔ bra a ɛfata koraa na apɔwmuden .
- Mma w’ani ngu sɛnkyerɛnne ahorow te sɛ ɔbrɛ a ɛba bere nyinaa, honam ani tuntum, aduan ho akɔnnɔ a ɛyera, ne mu duru a ɛso tew so. Wo ne wo duruyɛfo nka ho asɛm.
- Mma nnuru dodow bi a wo duruyɛfo akyerɛw ama wo no nmpa wo ti so da . Fa nnuru foforo ka wo ho bere nyinaa.
- Hyɛ aduruyɛ ho ID krataa anaa abɔso a ɛkyerɛ sɛ wowɔ Addison yare no bere nyinaa. Ebetumi aboa ma woagye wo nkwa wɔ tebea a egye ntɛmpɛ mu.
- Te ase sɛ Addisonian ahokyere yɛ aduruyɛ mu tebea a egye ntɛmpɛ. Ɛho hia sɛ wo ne w’abusua hu ne yare no ho sɛnkyerɛnne.
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