Momma yensua pii fa Leptin a ɛboa wo ma wohwɛ wo mu duru so wɔ kokoam no ho.

Ɛtɔ mmere bi a yɛn nyinaa haw yɛn mu duru ho, ɛnte saa? Nnipa binom pɛ sɛ wɔn mu duru so tew, na afoforo nso pɛ sɛ wɔma wɔn mu duru kɔ so yɛ nea ɛfata. So woasusuw pɛn sɛ adwinnade ketewaa bi wɔ yɛn nipadua mu a ɛboa ma yɛhwɛ yɛn mu duru so? Leptin yɛ kokoam nneɛma a ɛte saa no mu biako. Ɛnnɛ, momma yɛnka leptin ho asɛm wɔ ɔkwan tiawa bi a wubetumi ate ase so.

Dɛn ne Leptin?

Sɛ yɛbɛka no tiawa a, leptin yɛ hormone a wo nipadua mu srade nkwammoaa, anaa srade ntini na ɛyɛ . Ɛte sɛ sɛnkyerɛnne kwan so nhyehyɛe ketewaa bi a ɛboa wo ma wudi wo mu duru so bere tenten. Ɛyɛ dɛn na ɛyɛ saa? Leptin di wo kɔm so na ɛboa nso ma wote nka sɛ woama, anaasɛ wo bo amee .

Susuw ho saa kwan yi so: leptin te sɛ ɔbɔfo a ɔka srade dodow a wowɔ wɔ wo nipadua mu kyerɛ w’amemene. Nyansahufo huu leptin nnansa yi ara wɔ 1994. Enti nhwehwɛmu pii da so ara rekɔ so, sɛnea ɛbɛyɛ a wɔbɛte sɛnea ɛyɛ adwuma no ase pɛpɛɛpɛ. Wɔreyɛ nhwehwɛmu dedaw wɔ leptin mu wɔ dwuma a edi wɔ mu duru a wɔhwɛ so, Alzheimer yare , awo akwahosan, ne awo a wontumi nwo mu .

Sɛ wote sɛ leptin na ɛhwɛ mu duru so a, ebia wubesusuw sɛ, "Oh... enti misusuw sɛ ɛsɛ sɛ mehwehwɛ ɔkwan bi a mɛfa so adi leptin so." Nanso, sɛ yɛbɛka nokware a, saa hormone yi a wobɛdannan no nyɛ mmerɛw sɛnea wususuw no.

Dɛn na ɛba ankasa wɔ leptin ho?

Leptin adwuma titiriw ne sɛ ɛbɛboa wo ma wo nipadua mu duru akɔ so ayɛ kɛse. Ɛne sɛ, ɛboa ma aduan dodow a wudi ne ahoɔden dodow a wo nipadua de di dwuma no kari pɛ bere tenten. Leptin mma wo nte ɔkɔm nka bere nyinaa. Ɛsan nso di ɔkɔm ho nsɛnkyerɛnne a ɛba bere a nipadua no nhia ahoɔden, anaa calories .

Leptin yɛ adwuma titiriw denam w’amemene no fã bi a wɔfrɛ no hypothalamus a ɛka no so . Hypothalamus yɛ beae titiriw a wodi ɔkɔm ne ahoɔden a wɔde di dwuma so. Nanso, leptin agyefo wɔ nipadua no afã afoforo nso.

Nea ɛho hia ne sɛ ɛnyɛ sɛ leptin na ɛhyɛ wo kɔm dodow so kɛkɛ fi aduan biako so kosi foforo so. Mmom no, ɛboa ma wosakra w’adidi kwan bere tenten, hwɛ w’ahoɔden a wosɛe no so, na ɛboa ma wo mu duru kɔ so tra hɔ.

Sɛ worebɔ mmɔden sɛ wobɛtew wo mu duru so a, leptin dodow kɔ soro. Ɔkwan bɛn so na ɛno yɛ adwuma? Bere a wo nipadua mu srade so tew no, leptin dodow so tew. Eyi de sɛnkyerɛnne bi kɔ wo nipadua so, na ɛka sɛ, "Oh, mennidi sɛnea ɛsɛ, ɔkɔm de me." Eyi ma ɔkɔm de wo kɛse na w’akɔnnɔ. Eyi betumi ama woadi pii asen sɛnea ɛsɛ sɛ wudi. Ɛno nti na ɛtɔ mmere bi a ebetumi ayɛ den sɛ wobɛkɔ so atew wo mu duru so no.

Nyansahufo da so ara resua leptin ho ade. Wogye di sɛ ɛka:

• Wo nipadua mu nneɛma a ɛsakra no
• Endocrine nhyehyɛe, kyerɛ sɛ, hormone nhyehyɛe
• Nkwammoaa a ɛko tia nyarewa

Ɔkwan bɛn so na wɔhwɛ leptin dodow so?

Wo nipadua mu srade fitaa anaa srade nkwammoaa fitaa no na ɛyɛ leptin na eyi fi mu. Saa srade nkwammoaa fitaa yi ne srade titiriw a ɛwɔ yɛn nipadua mu.

Esiane sɛ leptin fi srade nkwammoaa mu nti, leptin dodow a ɛwɔ wo mogya mu no ne srade dodow a ɛwɔ wo nipadua mu no wɔ abusuabɔ tẽẽ. Sɛ yɛbɛka no tiawa a, sɛ wo nipadua mu srade sua a, ɛnde na leptin sua. Sɛ wowɔ nipadua mu srade pii a, ɛnde na wowɔ leptin pii.

Sɛ wo nipadua mu srade kɔ soro bere tenten a, leptin dodow kɔ soro. Nea ɛne eyi bɔ abira no, sɛ wo nipadua mu srade so tew a, leptin dodow so tew.

Sɛ leptin dodow kɔ soro a, dɛn na ɛba?

Ebia obi a wayɛ kɛse mmoroso wɔ leptin a ɛdɔɔso yiye wɔ ne nipadua mu. Wɔfrɛ eyi hyperleptinemia . Sɛ leptin kɔ soro wɔ saa kwan yi so a, tebea bi betumi aba a nipadua no ntumi nyɛ leptin ho biribi. Wɔfrɛ eyi leptin a wɔko tia .

Tebea afoforo a ebia ɛne hyperleptinemia wɔ abusuabɔ ne:

• Hahaahayɔ
• Aduan a ɛma obi yɛ ade tra so
• Ntini mu yare a ɛma nipadua no yɛ adwuma yiye
• mmerɛbo mu yare a srade wom a ɛnyɛ nsa ( NAFLD ) .
• Rabson-Mendenhall yare a ɛma obi nya ɔyare no

Dɛn ne Leptin a Ɛko Tia?

Sɛ wowɔ leptin a ɛko tia a, w’amemene no ntumi nyɛ leptin ho biribi sɛnea ɛsɛ. Ɛwom mpo sɛ leptin kɔ so de nsɛnkyerɛnne kɔ w'amemene mu de, nanso wunnya atenka a "ɛyɛ pɛ" no. Ne saa nti, wokɔ so didi, ɛwom mpo sɛ wowɔ srade pii wɔ wo nipadua mu de.

Esiane saa leptin a ɛda adi sɛ enni hɔ yi nti, wo nipadua susuw sɛ "ɔkɔm de wo." Nea ɛbɛyɛ na w’amemene no akora ahoɔden so no, ɛma w’ahoɔden so tew na ɛtew calories dodow a wohyew bere a woregye w’ahome no so. Eyi kyerɛ sɛ wo Basal Metabolic Rate (BMR) so tew.

Enti, leptin a ɛko tia no ma ɔkɔm de wo bere nyinaa, na wo BMR nso so tew. Eyi ma mu duru a ɛkɔ soro no yɛ kɛse.

Mprempren nyansahufo rebɔ mmɔden sɛ wɔbɛyɛ nnuru a ebetumi asa leptin a ɛko tia no.

Nsɛnkyerɛnne a ɛkyerɛ sɛ leptin ntumi nkɔ nipadua no mu

Nsɛnkyerɛnne atitiriw a ɛkyerɛ sɛ leptin ntumi nkɔ nipadua no mu ne ɔkɔm bere nyinaa, anaasɛ hyperphagia , ne aduan a obi di kɛse. Saa sɛnkyerɛnne ahorow yi ba bere a wowɔ nipadua mu srade a ɛboro so, ebia srade a ɛboro so mpo.

Nanso, ebia nneɛma afoforo pii na ɛde saa sɛnkyerɛnne ahorow yi ba, ɛnyɛ leptin a ɛko tia no nkutoo. Bere a nyansahufo da so ara resua leptin ho ade no, ebetumi aba sɛ wobehu leptin ho sɛnkyerɛnne pii daakye.

Sɛ wowɔ Leptin Deficiency a, dɛn na ɛba?

Leptin a wonnya nni, a wɔsan frɛ no hypoleptinemia no yɛ tebea a ɛntaa nsi koraa. Tebea titiriw a ɛbata eyi ho ne leptin a enni awo mu . Eyi yɛ awosu mu tebea a wɔde woo wo. Eyi kyerɛ sɛ wo srade ntini no ntumi nyɛ leptin.

Sɛ leptin yera a, wo nipadua susuw sɛ srade biara nni nipadua no mu. Eyi de ɔkɔm ne akɔnnɔ a wontumi nni so ba. Esiane eyi nti, mmofra nkumaa a wɔde awo wɔn a wonni leptin no nya kɛseyɛ mmoroso a ɛto so III na wɔkyɛ wɔ mmerantebere ne mmabaabere mu.

Saa tebea yi ne nyarewa afoforo pii nso wɔ abusuabɔ:

• Dyslipidemia (srade a ɛnkari pɛ, te sɛ srade ne triglycerides) .
• Mmerɛbo mu yare a srade wom
• Mmoawa a wɔtaa de nyarewa ba
• Hyperinsulinemia (insulin a wɔyɛ boro so) .
• Hypogonadotropic hypogonadism (ɔbarima ne ɔbea nna mu hormone dodow a ɛba fam) .

Ɔkwan bɛn so na wɔbɛhwɛ sɛnea leptin dodow te?

Mogya mu nhwehwɛmu betumi ahwɛ sɛnea wo leptin dodow te. Nanso, nnuruyɛfo ntaa nhwɛ sɛnea obiara wɔ leptin dodow. Wosusuw ho sɛ wɔbɛyɛ leptin nhwehwɛmu wɔ tebea horow yi mu nkutoo:

• Sɛ wo ba ketewa no wɔ kɛseyɛ mmoroso a ɛto so 3 a
• Sɛ woyɛ kɛse mmoroso na ɔkɔm de wo bere nyinaa a

Dɛn ne leptin dodow a ɛfata?

Mpɛn pii no, leptin dodow betumi afi:

• Wɔ mmea fam no: Nanogram 0.5 kosi 15.2 wɔ mililita biara mu ( 0.5 kosi 15.2 ng/mL ) .
• Wɔ mmarima fam no: nanogram 0.5 kosi 12.5 wɔ mililita biara mu ( 0.5 kosi 12.5 ng/mL ) .

Nanso, saa gyinapɛn ahorow a ɛfata yi betumi ayɛ soronko kakra wɔ lab biara mu. Enti, hwɛ hu sɛ wobɛhwɛ sɛnea ɛfata wɔ wo sɔhwɛ amanneɛbɔ no so, anaasɛ bisa wo duruyɛfo sɛ wowɔ nsɛmmisa bi fa nea efi mu ba no ho a.

Mɛyɛ dɛn atumi ama me leptin dodow akɔ soro?

Nokwarem no, pii nni hɔ a wubetumi ayɛ de ama wo leptin dodow akɔ soro na ama ɔkɔm anaa aduan ho akɔnnɔ so atew. Ɛte saa efisɛ wo leptin dodow ne srade dodow a wowɔ wɔ wo nipadua mu no wɔ abusuabɔ tẽẽ.

Nhwehwɛmu bi daa no adi sɛ nnipa a wɔnna sɛnea ɛsɛ no wɔ ghrelin (ɔkɔm hormone) pii na leptin nso sua. Enti, nna a ɛfata a wubenya no betumi aboa ma wo hormone ahorow no ayɛ nea ɛkari pɛ.

Nyansahufo aka sɛ leptin ne triglycerides wɔ abusuabɔ(Eyi nso yɛ srade bi a wɔfrɛ no lipids). Nhwehwɛmu ahorow bi ada no adi sɛ sɛ triglyceride dodow kɔ soro a, ɛka ɔkwan a leptin fa so yɛ adwuma. Nanso adwene ahorow wɔ adesua ahorow yi ho. Nyansahufo binom susuw sɛ aduan a wɔayɛ sɛ ɛbɛma triglycerides so atew betumi aboa ma leptin dodow akɔ soro, nanso afoforo ne no nyɛ adwene.

Nnuan bɛn na leptin pii wom?

Leptin yɛ hormone a wo nipadua yɛ, ɛnyɛ aduannuru te sɛ vitamin C anaa protein. Enti, aduan biara nni hɔ a leptin nni mu.

Esiane sɛ leptin yɛ ade foforo koraa a wɔahu nti, nyansahufo da so ara resua ho ade pii, titiriw sɛnea ɛka kɛseyɛ mmoroso ne mu duru a ɛso tew. Sɛ wo nipadua mu srade sua a, ebetumi ayɛ den sɛ wobɛtew wo mu duru so efisɛ dwuma a leptin di wɔ nipadua no "ɔkɔm" sɛnkyerɛnne a ɛma ɛyɛ adwuma no mu.

Nkrasɛm a Wɔde Kɔ Fie

Okay, enti sɛnea yɛaka leptin ho asɛm no, wubetumi akae eyi:

• Leptin yɛ hormone a wo srade nkwammoaa na ɛyɛ .
• Ade titiriw a ɛwɔ eyi ho ne sɛ ɛboa wo ma wudi wo mu duru so bere tenten na ɛma wote nka sɛ "woayɛ ma" .
• Sɛ wo nipadua mu srade kɔ soro a, leptin dodow kɔ soro , na sɛ wo nipadua mu srade so tew a, leptin dodow so tew.
• Leptin resistance yɛ bere a nipadua no wɔ leptin nanso amemene no ntumi nyɛ ho hwee yiye. Eyi betumi ama obi mu duru ayɛ kɛse.
• Leptin a enni nipadua mu no ho yɛ na koraa .
• Aduan biara nni hɔ a leptin nni mu, efisɛ wɔyɛ no wɔ nipadua no mu.
• Asetra pa, titiriw nna pa a wobɛda , betumi aboa ma hormone ahorow akari pɛ.

Sɛ wo mu duru ho asɛm haw wo anaasɛ wuhia afotu wɔ sɛnea wobɛtew wo mu duru so yiye ho a, wo ne wo duruyɛfo nkasa. Wubetumi nso akɔ oduruyɛfo bi a ne ho akokwaw wɔ hormone ahorow mu, oduruyɛfo a ɔhwɛ nipadua no mu ntini mu yare so, ma wasusuw nhyehyɛe ahorow a wɔde siesie wo mu duru ho. Nea ɛho hia sen biara ne sɛ wubedi kan ahwɛ w’akwahosan so.

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