So wo nsa ne wo nan te nka sɛ wo ho ayɛ wo yaw anaasɛ worehyew? Eyi betumi ayɛ Small Fiber Neuropathy!

So woate nka pɛn sɛ wo nsa ne wo nan ho yɛ wo yaw, anaasɛ ɔhyew te sɛ ntɛtea a wɔrewea wo nsa ne wo nan mu pɛn? Mmu saa sɛnkyerɛnne ahorow yi ngu kɛkɛ sɛ biribi a ɛba ara kwa, ɛnte saa? Efisɛ ɛtɔ mmere bi a ebia tebea bi wɔ saa sɛnkyerɛnne ahorow yi akyi a ɛsɛ sɛ wɔhwɛ so kakra. Ɛnnɛ, yɛrebɛka tebea bi a wɔfrɛ no Small Fiber Neuropathy (SFN) , a ɛba bere a ntini nketenkete a ɛwɔ yɛn nipadua mu no asɛe no ho asɛm.

Enti, dɛn ne Small Fiber Neuropathy?

Sɛ yɛbɛka no tiawa a, eyi yɛ ntini mu yare a ɛka ntini a ɛwɔ akyi no ho . Saa tebea yi ba bere a ntini nketenkete a ɛyɛ mmerɛw yiye a ɛwɔ yɛn honam ani no sɛe esiane biribi nti. Saa ntini nketenkete yi na ɛde nsɛnkyerɛnne kɔ amemene no mu wɔ yɛn nipadua no yaw ne yɛn hyew ho. Enti sɛ eyinom sɛe, sɛnea yɛadi kan aka no, nsa ne anan betumi ayɛ mmerɛw ne ɛyaw a ɛyɛ hyew.

Nanso, ɛnyɛ nsa ne anan nkutoo na eyi ka. Ebetumi aka ntini nketenkete afoforo a ɛhwɛ yɛn nipadua mu dwumadi ahorow a ɛho hia te sɛ mogya mmoroso ne koma a ɛbɔ so nso .

Ɛtɔ mmere bi a saa SFN sɛnkyerɛnne ahorow yi betumi ayɛ nea emu yɛ den yiye, na ebetumi anya w’asetra mu nkɛntɛnso kɛse . Ɛwom sɛ eyi nyɛ tebea a emu yɛ den a ɛde nkwa to asiane mu de, nanso ɛtɔ mmere bi a ebetumi ayɛ tebea foforo a emu yɛ den ho sɛnkyerɛnne. Ɛno nti na nnuruyɛfo bɔ mmɔden sɛ wobehu nea ɛde tebea yi ba, sa, na wɔkyerɛw nnuru nso ma obi de siw sɛnkyerɛnne a ɛyɛ yaw yi so no.

Saa tebea yi abu so dɛn?

Nokwarem no, eyi nyɛ tebea a ɛtaa ba. Sɛnea nhwehwɛmu bi kyerɛ no, nnipa bɛyɛ 53 wɔ nnipa 100,000 biara mu wɔ wiase nyinaa na wɔwɔ ntini nketenkete a wɔfrɛ no fiber neuropathy. Nanso, nhwehwɛmufo gye di sɛ dodow no betumi akɔ soro koraa. Wogye di sɛ ɛnyɛ obiara a ɔwɔ yare no na wohu no yiye. Enti, ebia nnipa pii wɔ saa ɔhaw yi sen sɛnea yesusuw.

Dɛn ne sɛnkyerɛnne ahorow a ɛkyerɛ sɛ obi anya ntini mu yare a wɔfrɛ no small fiber neuropathy (SFN)?

Saa tebea yi ho sɛnkyerɛnne betumi ayɛ soronko wɔ onipa biara ho. Nanso, sɛnkyerɛnne a ɛtaa ba ntɛm ne "pins-and-needles" ɛyaw anaasɛ ɔhyew a ɛba nsa ne anan mu. Ɛtɔ mmere bi a, saa sɛnkyerɛnne ahorow yi ba na ɛkɔ, ɛtɔ mmere bi a ɛkɔ so daa, na mpɛn pii no, bere kɔ so no, emu yɛ den.

Nsɛnkyerɛnne afoforo a wobetumi ahu ne:

• Feeling dizzy , anaasɛ te sɛ nea worebɛtotɔ piti.
• Sɛ wote nka sɛ wo koma rebɔ ntɛmntɛm (koma a ɛbɔ) .
• Nnipa a wɔyɛ mmerɛw .
• Ɛyaw, ɔhyew, anaa awɔw a wontumi nte nka wɔ nipadua no fã ketewaa bi.
• Yafunu mu akisikuru, aduan a ɛnyɛ dɛ.
• Fifiri a ɛba sen sɛnea ɛte daa.

Susuw sɛnea ɛbɛyɛ wo yaw sɛ wote nka sɛ wɔde nnua rebɔ wo nsa ne wo nan, anaasɛ wɔde ogya mpo rehyew, bere mpo a wote hɔ ara kwa no ho hwɛ.

Dɛn nti na yenya ntini mu yare nketenkete (SFN)? Dɛn na ɛde ba?

Nea ɛyɛ nwonwa no, bɛyɛ ntini nketenkete a ɛma ntini mu yare no fã ba a ntease biara nnim . Nnuruyɛfo frɛ eyi " idiopathic small fiber neuropathy." Ɛno kyerɛ sɛ wontumi nhu nea ɛde ba ankasa.

Nanso, nhwehwɛmu ada no adi sɛ nyarewa ahorow, awosu mu tebea horow bi, ne awuduru bi a obi de ne ho hyɛ mu nso betumi de eyi aba.

Saa tebea yi nso betumi afi nyarewa bi mu aba.

Asikreyare ne yare titiriw a ɛtaa ka eyi. Sɛ ɛno da nkyɛn a, ɛda adi sɛ nyarewa a edidi so yi nso na ɛde SFN ba:

• Nsã a wɔnom ho haw .
• Nyarewa a nipadua no mu tumi a ɛko tia nyarewa a ayɛ mmerɛw de ba, sɛ nhwɛso no , Celiac yare , Sarcoidosis , anaa Sjögren’s syndrome .
• Glucose a ɛnyɛ adwuma yiye (Glucose a wontumi nnye ntom) .
• Nyarewa bi a ɛde ɔyare ba, sɛ nhwɛso no Hepatitis C anaa HIV (Human Immunodeficiency Virus) .
• Nneɛma a ɛma nipadua no yɛ adwuma .
• Thyroid yare a ɛwɔ nipadua no mu .
• Sepsis yɛ ɔyare mmoawa a emu yɛ den.
• Vitamin B a enni nipadua mu.

Ebia efi awosu mu tebea horow bi nso.

Awosu mu nsakrae a ɛba awosu mu nkwaadɔm a ɛboa yɛn nkwammoaa ma ɛyɛ anyinam ahoɔden nsɛnkyerɛnne na ɛde fa ntini mu no nso betumi ama SFN aba. Nyarewa afoforo bi a wonya fi awo mu bi ne:

• Ehlers-Danlos yare a ɛma obi nya ɔyare no
• Fabry yare no
• Abusua mu amyloidosis a ɛma obi nya amyloidosis
• Pompe yare no
• Porphyria a wɔfrɛ no Porphyria
• Wilson yare no

Nnuru ne awuduru bi...

Asiane a ɛwɔ hɔ sɛ obi benya ntini mu yare nketenkete nso betumi ayɛ kɛse bere a wɔde nnuru bi redi dwuma no. Nhwɛso ahorow:

• Nnuru bi a ekum ɔyare mmoawa , sɛ nhwɛso no , Metronidazole , Nitrofurantoin, ne Linezolid .
• Nnuru a wɔde sa yare , te sɛ Bortezomib , Thalidomide , ne Vincristine (Oncovin) .
• Nnuru a esiw tumor necrosis factor ano , sɛ nhwɛso no , etanercept .

Nneɛma bɛn na ɛma yare no ho sɛnkyerɛnne no yɛ kɛse? (Nneɛma a ɛkanyan) .

Mpɛn pii no, nneɛma a ebetumi akanyan saa sɛnkyerɛnne ahorow yi ne mframa a ɛyɛ nwini a ɛbɔ honam ani , anaasɛ ntama bi a ɛbɔ honam ani . Fa no sɛ, sɛ woda anadwo na mpa so ntama no repetepete wo nan so a, anka wobɛte nka sɛ wo ho ayɛ wo yaw na ɛyɛ yaw a wuntumi nnyina ano... Biribi ketewa te sɛ ɛno mpo betumi de ɛyaw kɛse aba saa nkurɔfo yi so.

Dɛn ne nsɛnnennen a ɛwɔ tebea yi mu? So ɛsɛ sɛ misuro?

Small fiber neuropathy betumi atew sɛnea wote ɛyaw nka no so. Sɛ nhwɛso no, sɛ woka biribi a ɛyɛ hyew wɔ akwanhyia mu a, ɛda adi sɛ wobɛhyew a wunhu. Ebetumi ama w'adwene nso ayɛ wo yaw na aka wo nantew . Enti, ɛda adi sɛ wobɛhwe ase, ɛnte saa? Enti ɛsɛ sɛ wohwɛ yiye wɔ saa nneɛma yi nso ho.

Ɔkwan bɛn so na oduruyɛfo hu eyi? (Nyare a Wɔahu) .

Oduruyɛfo bi bedi kan ayɛ nipadua mu nhwehwɛmu na wabisa w'ayaresa ho abakɔsɛm . Nhwehwɛmu biako biara nni hɔ a ebetumi ahu ntini nketenkete a ɛwɔ ntini mu yare no pɛpɛɛpɛ. Nanso, sɔhwɛ ahorow pii wɔ hɔ a wɔtaa yɛ:

• Electromyography (EMG) : Eyi sɔ anyinam ahoɔden dwumadi a ɛwɔ ntini ne ntini mu hwɛ.
• Awosu mu nhwehwɛmu : Hwɛ sɛ ebia efi awosu mu ba anaa.
• Mfonini a wɔde yɛ nhwehwɛmu : Nneɛma te sɛ CT scan anaa MRI scan .
• Ntini mu ntini mu nhwehwɛmu : Hwɛ ahoɔhare a nsɛnkyerɛnne fa ntini mu.
• Skin biopsy - nerve fiber density tests : Wɔfa honam ani hwɛbea ketewaa bi na wɔde microscope hwehwɛ mu de hwɛ ntini dodow a ɛwɔ hɔ.
• Quantitative Sudomotor Axon Reflex Test (QSART) : Eyi sɔ ntini a ɛhwɛ fifiri so no dwumadi hwɛ.

Nea ɛka ho no, ebia nnuruyɛfo nso bɛsɔ tebea afoforo te sɛ asikreyare a ebetumi de nhama nketenkete a ɛma ntini mu yare aba no ahwɛ.

Dɛn ne ayaresa ahorow a wɔde sa eyi? So wobetumi asa no yare?

Sɛ nnuruyɛfo resa tebea yi a, wɔde wɔn adwene si ɛyaw a ɛde ba no a wɔbɛtew so titiriw.Nnuru ne ayaresa afoforo wɔ hɔ. Mpɛn pii no, ntini nketenkete a ɛma ntini mu yare yɛ ɔhaw a efi tebea foforo mu ba, enti ɛho hia sɛ wɔsa tebea a ɛde ba no nso .

Nnuru a wɔde sa ɛyaw

Nnuru ahorow pii wɔ hɔ a wobetumi de asiw ɛyaw ano:

• Nnuru bi a wɔde ko tia akisikuru , te sɛ Gabapentin , Pregabalin , ne Topiramate , betumi aboa ma ntini mu yaw so atew.
• Nnuru bi a ekum adwenemhaw , te sɛ amitriptyline , nortriptyline , ne desipramine , nso ye ma ntini mu yaw.
• Nnuru a wɔde kum nipadua no so : Sɛ nhwɛso no , lidocaine aduru anaa capsaicin aduru. Eyinom ma ahotɔ bere a wɔde gu baabi a ɛyɛ yaw no.

Kae sɛ ɛho hia paa sɛ wode nnuru di dwuma sɛnea oduruyɛfo kyerɛ no pɛpɛɛpɛ.

Dɛn na wubetumi ahwɛ kwan bere a wo ne tebea yi te ase no?

Small fiber neuropathy ba nkakrankakra paa . Ɛtɔ mmere bi a, yare no ho sɛnkyerɛnne betumi asɛe na afei atra hɔ mfe pii. Nhwehwɛmu bi daa no adi sɛ nnipa a wɔwɔ ntini nketenkete a ɛwɔ ntini mu yare no mu 13% kosi 36% awiei koraa no wonya nhama akɛse a ɛma ntini mu yare, tebea a ɛka ntini akɛse . Eyi betumi ama woahwere nkate te sɛ wo ho a wobɛte nka sɛ woka wo ho na wowosow, te sɛ nea wohyɛ nsateaa.

Wo nkɔmhyɛ wɔ ayaresa akyi no gyina nea ɛde wo SFN ba no so. Sɛ nhwɛso no, sɛ wowɔ asikreyare a, ebehia sɛ wonom asikreyare aduru wo nkwa nna nyinaa. Enti, wo ne wo duruyɛfo nka wo tebea no ho asɛm ne sɛnea ayaresa betumi aboa ma woadi wo yaw ne sɛnkyerɛnne afoforo so.

So eyi nya nkwa nna so nkɛntɛnso?

Dabi, ntini nketenkete a ɛma ntini mu yare no ankasa remma wo nkwa nna nyɛ tiaa . Nanso, sɛ tebea bi wɔ hɔ a ɛde ba, te sɛ asikreyare anaa HIV a, ebetumi aka bere tenten a wotra ase.

Mɛyɛ dɛn ahwɛ me ho?

Nneɛma a ɛho hia sen biara a wubetumi ayɛ de ahwɛ wo ho no mu biako ne sɛ wubedi ɛyaw a fiber neuropathy nketenkete de ba no ho dwuma. Ɛda adi sɛ wo duruyɛfo bɛkyerɛw nnuru a wɔde sa ɛyaw, nanso ebia wobɛpɛ sɛ wususuw nhyehyɛe ahorow a wɔde siw ɛyaw ano nso ho . Ebia eyinom bi ne afotu ne ayaresa, apɔw-mu-teɛteɛ, ne aduru a wɔde twitwiw nipadua anaa nipadua mu ayaresa.

Bere bɛn na ɛsɛ sɛ mesan kɔ oduruyɛfo nkyɛn bio?

Fiber neuropathy ho sɛnkyerɛnne nketenkete betumi asesa na bere kɔ so no, ayɛ kɛse. Sɛ wowɔ SFN a, ka kyerɛ wo duruyɛfo sɛ wuhu sɛnkyerɛnne ahorow a efii ase wɔ wo nipadua no fã biako na afei ɛkɔɔ so wɔ ɔfã foforo a. Nhwɛsoɔ:

• Sɛ afei na wobetumi ate ɛyaw a ɛte sɛ dua" a ɛwɔ me nan mu no nka wɔ me nsa nso mu a.
• Sɛ ɛyaw a ɛtaa ba no akɔ soro, anaasɛ ɛyaw no mu ayɛ den kɛse a.
• Sɛ sɛnkyerɛnne foforo ada adi, te sɛ adwenemhaw anaasɛ ɛyɛ den sɛ ɔbɛnantew.

Ɛyɛ papa sɛ wobɛkɔ oduruyɛfo nkyɛn ntɛm wɔ mmere a ɛte sɛɛ mu.

Nsɛmmisa a ɛho hia bɛn na ɛsɛ sɛ wobisa oduruyɛfo no?

Sɛ wokɔ oduruyɛfo nkyɛn a, kae sɛ wubebisa nsɛm yi:

• Dɛn na ɛde me sɛnkyerɛnne ahorow no ba?
• So me yare no ho sɛnkyerɛnne no bɛkɔ so asɛe?
• Ayaresa bɛn na wɔkamfo kyerɛ ma me?
• So menya saa tebea yi daa?

Sɛ wuhu nsɛmmisa yi ho mmuae a, ɛbɛma woama emu ada hɔ kɛse.

Enti, dɛn na ɛsɛ sɛ yɛkae fi eyi mu? (Nkrasɛm a Wɔde Kɔ Fie)

Small fiber neuropathy (SFN) yɛ tebea a enni sabea a ɛma akwaa a ɛyɛ mmerɛw, ɛhyew, na ɛyɛ yaw a ebetumi aka w’asetra pa. Ɛtaa da adi sɛ tebea foforo a ɛda adi, a ebetumi ayɛ nea emu yɛ den ho sɛnkyerɛnne.

Nnuruyɛfo sa SFN denam tebea a ɛwɔ ase no a wɔhwɛ so no so. Ayaresa ne nhyehyɛe ahorow nso wɔ hɔ a ɛbɛboa ma wɔadi ɛyaw ne sɛnkyerɛnne afoforo a ɛka ho no ho dwuma. Sɛ wo nsa ne wo nan ho yɛ wo yaw anaasɛ worehyew a, mmu w’ani ngu so na kɔ oduruyɛfo nkyɛn. Saa sɛnkyerɛnne ahorow yi betumi ayɛ tebea bi a emu yɛ den ho sɛnkyerɛnne a edi kan. Mma ɛnhaw wo, sɛ wohu wo yare no na wɔsa wo yare ntɛm a, mpɛn pii no wubetumi adi tebea no so.

` Small Fiber Neuropathy, SFN, ntini mu yaw, akisikuru, akisikuru, asikreyare, ntini mu yare