Yala aw ye ‘ Stem Cells ’ daɲɛ mɛn ka kɔrɔ wa? N’a sɔrɔ i y’o mɛn dɔgɔtɔrɔ dɔ fɛ, telewisɔn ka ɲɛjirali dɔ la, walima kunnafonisɛbɛn dɔ kɔnɔ. Hali n’a bɛ se ka kɛ ko nin ye barokun gɛlɛn ye, tiɲɛ na, o jirisunw ye fɛn kabakomaw dɔ ye an farikolo la. Bi, an bɛna kuma o kan cogo nɔgɔman na kosɛbɛ, cogo la min bɛ se ka faamuya.
N’an y’a fɔ cogo nɔgɔman na, o jirisunw ye mun ye?
Miiri k’a filɛ, Lego suguya kelen bɛ i bolo. I bɛ se ka baara kɛ n’o Lego yɔrɔw ye walasa ka so jɔ, mobili, kurun, fɛn o fɛn i b’a fɛ. Stem cellules bɛ o cogo la.
Seliluw ye selilu "basic" walima "master" sugu dɔ ye an farikolo la min bɛ se ka kɛ selilu kɛrɛnkɛrɛnnen suguya wɛrɛ ye.
Misali la, jirisunba dɔ bɛ se ka bonya ka kɛ farilajidɛsɛ ye, ka kɛ kunsɛmɛnasumaya ye ( nɛrɛmuguma selilɛri), dusukunnabanakisɛ, kolotuguda , walima joli kuru. Ani fana, o farikolokisɛw bɛ se ka jirisunba caman dilan, o kɔrɔ ye ko u bɛ se ka tila ka farikolokisɛw kɛ i n’a fɔ u yɛrɛ siɲɛ caman. O seko kabakoma in de y’a to u ye nafaba sɔrɔ furakɛli la.
O la sa, mun na o jirisunw nafa ka bon kosɛbɛ?
O farikolokisɛw nafa ka bon kosɛbɛ furakɛli ɲinini nataw la k’a sababu kɛ u seko ye. U nafa ka bon kunba saba kosɔn.
1. Furakɛli minnu bɛ kɛ ni selilɛriw ye: Miiri k’a filɛ, dusukun tantanni dɔ kɛra mɔgɔ dɔ la ani a dusukun yɔrɔ dɔ sara ani a barika dɔgɔyara. Dɔnniyakɛlaw dalen b’a la ko don nataw la, u bɛna se ka baara kɛ ni jirisunw ye walasa ka dusukunnabanakisɛ kura kɛnɛmanw dilan ani k’u bila yɔrɔ tiɲɛnen na walasa ka dusukun segin a cogo kɔrɔ la . an bɛ min wele ko furakɛli min bɛ mɔgɔ lasegin , o ye nin ye . nin fɛɛrɛ in bɛ ka kɛ kaban jolibana ni kansɛri dɔw la ka ɲɛ .
2. Walasa k’a faamu banaw bɛ sɔrɔ cogo min na:Dɔnniyakɛlaw bɛ se ka misali la, jirisunba dɔ kɔlɔsi, a bɛ bonya ka kɛ farikolojidɛsɛbanakisɛ ye laboratuwari kɔnɔ. O b’a to u bɛ se ka sɛgɛsɛgɛli kɛ tigitigi min bɛ kɛ farikoloɲɛnajɛw la banaw la i n’a fɔ Parkinson ka bana walima Alzheimer bana . Bana dɔ bɛ sɔrɔ cogo min na tigitigi, o faamuyali bɛ se ka dɛmɛ don ka furaw sɔrɔ.
3. Walasa ka fura kuraw sɛgɛsɛgɛ: Sani fura kura ka di mɔgɔw ma ka a sɛgɛsɛgɛ, a ka kan ka a dɔn ni a farati tɛ ani ni a bɛ se ka kɛ. O la, farikolokisɛ kɛrɛnkɛrɛnnen minnu bɛ tali kɛ bana kofɔlen in na (misali la, kɔnɔbolibanakisɛw) bɛ se ka dabɔ laboratuwari kɔnɔ ka bɔ jirisunw na, wa fura kura bɛ se ka kɛ o farikolokisɛw la ani a nɔ bɛ se ka sɛgɛsɛgɛ.
Sɔgɔsɔgɔninjɛ suguya jɔnjɔnw ye jumɛnw ye?
Sɔgɔsɔgɔninjɛ suguya fla de bɛ yen. An ka ninnu lajɛ u danma.
| Seli suguya | Ɲɛfɔli nɔgɔman |
|---|---|
| Denmisɛnninw ka jirisunw | Olu bɛ sɔrɔ den fɔlɔw la minnu dira, minnu ma baara kɛ ni u ye, bangekɔlɔsi in vitro (IVF) kɔfɛ. Se kabakoma bɛ o farikolokisɛw la ka kɛ farikolokisɛ suguya o suguya ye. O de y’a To u bɛ Weele fana ko ‘pluripotent’ . Seba bɛ u la ka farikolo yɔrɔw ni farikolo yɔrɔw dilan minnu tiɲɛna bana fɛ. |
| Balikuw ka jirisunw | Hali n’u tɔgɔ ka ca, o farikolokisɛw bɛ sɔrɔ denyɛrɛniw, denmisɛnw ani mɔgɔkɔrɔbaw farikolo la. U tɛ se ka kɛ fɛn caman ye i n’a fɔ denso kɔnɔnatumuw. Misali la, balikukalan dɔ min bɛ fari la, o bɛ se ka farikolokisɛ caman dɔrɔn de dilan. Nka u nafa ka bon kosɛbɛ fana. Kɔnɔnatumu joli la, jirisunw fana bɛ o kulu in na. |
| Induced Pluripotent Stem Cells (iPSCs) . | Nin ye dɔnniyako ɲɛtaa laban ye. Sisan, dɔnnikɛlaw bɛ se ka balikukalan nafama dɔ ta, i n’a fɔ i farikolokisɛ, ka fɛn dɔ Changer fitini kɛ jamu la laboratuwari kɔnɔ, ka segin k’a tigɛli kɛ denso kɔnɔ ‘se bɛ se ka ɲɛnamaya’. Nin ye bɔnɛba ye, bawo a bɛ a yɛrɛ tanga jogoɲumanya koɲɛw ma minnu bɛ tali kɛ denw baara la. |
Furakɛli jumɛnw bɛ kɛ sisan ni o jirisunw ye?
Mɔgɔ caman b’a miiri ko jirisunw bɛ se ka bana bɛɛ furakɛ, nka tiɲɛ tɛ kelen ye.
, furakɛli min dabɔra diɲɛ kɔnɔ , o ye kolotugudaw cili ye min dabɔra kosɛbɛ ani ka ɲɛ . O ye joli-sira-funu-banakisɛw cili ye. Olu bɛ se ka sɔrɔ kolotugudaw walima denso joli la.
Nin furakɛli in bɛ kɛ kosɛbɛ:
- Joli kansɛriw kama: Misali la, banaw i n’a fɔ jolidɛsɛ ni jolidɛsɛ .
- Bana wɛrɛ minnu bɛ sɔrɔ joli fɛ: Bana minnu bɛ sɔrɔ i n’a fɔ jolidɛsɛ sikili .
- Walasa ka kolotugudaw jɔ kokura minnu tiɲɛna kansɛri furakɛli fɛ: Nin furakɛli in bɛ kɛ ka kolotugudaw lasegin minnu tiɲɛna ni chimiothérapie walima radiyodisiyɔn ye.
Min nafa ka bon, o ye ko bana wɛrɛw furakɛli minnu bɛ kɛ ni jirisunw ye, olu fanba (misali la, jolidɛsɛ, sukarodunbana, Parkinson) bɛ ɲinini senfɛ hali bi . O la, ni aw ye o furakɛli sugu mɛn yɔrɔ dɔ la, a nafa ka bon kosɛbɛ aw ka miiri siɲɛ fila ani ka kuma aw ka dɔgɔtɔrɔ fɛ siga t’a la sani aw ka desizɔn ta.
Yala farati dɔw bɛ nin furakɛli ninnu na wa?
Ɔwɔ, i n’a fɔ furakɛli bɛɛ, farati dɔw bɛ yen.
- Ni o farikolokisɛw bonyalen don k’a sɔrɔ u ma se ka u yɛrɛ minɛ, a bɛ se ka kɛ kansɛribanakisɛw bɛ sɔrɔ.
- Jamu tiɲɛni bɛ se ka kɛ farikolokisɛw la minnu falen don laboratuwari kɔnɔ.
- Tuma dɔw la, farikolo bɛ se ka nin farikolokisɛ kura ninnu dɔn ko u ye "dunanw" ye, ka ban (ka bin) u kan.
- Farati dɔw fana bɛ sɔrɔ fɛɛrɛw la (misali la, opereli) minnu bɛ farikolokisɛw lajɛ walima ka u pikiri kɛ farikolo la.
Gɛlɛyaw minnu bɛ sɔrɔ jirisunw ɲinini na
Hali ni ɲininiw bɛ senna balikuw ka jirisunw kan kabini san tan caman, ɲinini minnu kɛra denw ka jirisunw kan, olu daminɛna dɔrɔn san 1998. O la, caman bɛ yen hali bi ka sɔrɔ u ko la.
gɛlɛyabaw dɔ ye jogoɲumanya koɲɛw ye . Hakilina tɛ kelen ye farikolokisɛw sɔrɔli kan denw na, wa mɔgɔ dɔw tɛ sɔn o ɲinini ma.
Gɛlɛya wɛrɛ ye balikuw ka jirisunw falenni gɛlɛya ye laboratuwari kɔnɔ ani u ka jamu nafama faratiba. Nin bɛɛ n’a ta, dɔnnikɛlaw b’a ɲini hali bi ka o farikolokisɛ kabakomaw gundo dabɔ.
Take-Home cikan
- Stem cellules ye "master" cellules ye minnu bɛ se ka kɛ cellule suguya bɛɛ ye farikolo la.
- Sisan, ninnu bɛ baara kɛ ka ɲɛ, wa u dagalen don fɔlɔ kolotugudaw cili la joli kansɛriw kama i n’a fɔ jolidɛsɛ.
- Banakisɛw furakɛli minnu bɛ kɛ ni jirisunw ye i n’a fɔ Parkinson, sukarodunbana ani dusukunnabana, olu bɛ ɲinini senfɛ hali bi, wa u ma kɛ furakɛli kɛcogo kɔrɔw ye fɔlɔ.
- Hali ni tɔnba dɔw b’a fɔ ko u bɛ furakɛli kɛ ɲinini siratigɛ la, u lakanani n’u ka ɲɛtaa tɛ se ka dafa.
- Sani aw ka desizɔn ta jirisunw furakɛli suguya bɛɛ la, aw ye aw jija ka taa aw ka dɔgɔtɔrɔ dɔnbaga fɛ ani ka laadilikan ɲumanw ɲini.
Kɔnɔnatumuw, jirisunw, jirisunw ɲinini, selilɛriw furakɛli, furakɛli ɲininiw, kolotugudaw cili, kolotugudaw cili, denso kɔnɔfɛnw, balikuw ka jirisunw
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Ko foyi ma bila fɔlɔ. Aw ka kuma fɔlen fara a kan yan a siɲɛ fɔlɔ la.
Aw ka kuma fɔlen fara a kan