Ðe nèle atikewo nom be wòaɖe wò ʋumemi dzi akpɔtɔa? Ne nenemae la, ke ɖewohĩ èle atikewo ƒe hatsotso aɖe si woyɔna be ‘statins’ zãm. Ne èdze atike sia zazã gɔme vɔ la, ɖe nètsia dzodzodzoe ɣeaɖewoɣi, èŋlɔa nuwo be, alo ɖe nusi míeyɔna be ‘ahɔhɔ̃ ƒe afu’ nɔa ŋuwòa? Esia nye kuxi si le ame geɖe ŋu. Eyata egbea, mina míakpɔ nusi tututu wònye.
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Gbã la, mina míakpɔe ɖa, nukae nye statin sia?
Kpuie ko la, ʋumemi nye nusi le abe wax ene, si me ami le le míaƒe ʋu me. Míaƒe ŋutilã hiã ʋumemi sia be wòatu lãmenugbagbeviwo ɖo ahawɔ lãmetsiŋusẽwo, gake eƒe agbɔsɔsɔ fũ menyo o. Vevietɔ ne ʋumemi "vɔ̃ɖi", alo LDL (Low-Density Lipoprotein) ʋumemi , sɔ gbɔ la, ate ŋu aƒo ƒu ɖe míaƒe ʋukawo ƒe gliwo ŋu eye wòaxe wo. Esia nye nu vevi aɖe si hea nɔnɔme siwo me afɔku le abe dzidɔ kple ʋusɔgbɔdɔ ene vɛ.
Statin-tikewo wɔa dɔ to LDL ʋumemi gbegblẽ si aklãa wɔna dzi ɖeɖe kpɔtɔ me. Eya ta masɔ be míayɔ atike siawo be atike siwo hiã vevie eye woxɔa agbe na amesiwo ate ŋu axɔ dzidɔ o.
Eyata ɖe ‘ahɔhɔ̃ ƒe afu’ ŋutinya sia nye nyateƒea?
Togbɔ be wobua statin be ele dedie ŋutɔ na ame akpa gãtɔ, abe atike ɖesiaɖe ene hã la, woate ŋu ahe nugbegblẽ suesuesuewo vɛ. Le kpɔɖeŋu me, lãmekawo ƒe vevesese, aklã ƒe gbegblẽ, kple ‘ahɔhɔ̃ ƒe fuɖename’, alo ŋkuɖoɖonudzi kple susu ƒe kuxiwo le wo dome.
‘Ahɔhɔ̃ me Fuɖename’ nye nɔnɔme si me tɔtɔ kple tɔtɔ si gbɔ eme le. Bu eŋu kpɔ, èŋlɔ afisi nèda wò safuiwo ɖo be, ɖewohĩ èʋu fridzia hegblẽ safuia ɖe eme eye emegbe nàdie emegbe. Esiawo ƒomevi dzɔna le nɔnɔme sia me.
FDA si le U.S. gɔ̃ hã tsɔ ŋkuɖoɖonudzi ƒe dɔmawɔmawɔ nyuie kple tɔtɔ de eme be wonye "nusiwo mesẽ o eye woate ŋu atrɔ wo" ƒe nugbegblẽ le statin ƒe dzesiwo ŋu. Lãmetsiŋusẽ le vevie na míaƒe ahɔhɔ̃ ƒe dɔwɔwɔ. Le nyateƒe me la, míaƒe ʋumemi katã ƒe 25% le ahɔhɔ̃a me. Eyata susu le eme be míasusui be ʋumemi dzi ɖeɖe kpɔtɔ kple statin ate ŋu akpɔ ŋusẽ aɖe ɖe ahɔhɔ̃a dzi.
Gake eŋutinunyalawo gblɔ be mehiã be woatsi dzi fũu akpa le esia ŋu o. Numekuku geɖe meɖo kpe edzi haɖe be kadodo aɖeke mele atike sia kple ŋkuɖoɖonudzi ƒe dɔmawɔmawɔ nyuie dome tẽ o.
Zi geɖe la, dzesi siawo ate ŋu anye atikewɔwɔ me nɔnɔme bubu si gbɔ wòtso ƒe dzesi. Vevietɔ ne ŋkuɖoɖonudzi ƒe kuxiwo abe esia ene do mo ɖa le ƒe titina alo ame tsitsiwo ŋu la, ate ŋu anye Alzheimer-dɔlélea ƒe dzesi gbãtɔ.
Eyata nu gbãtɔ si ɖɔkta bunae nye be, "Ðe atikeawo gbɔe esia tso nyateƒea? Alo ɖe kuxi bubu aɖe hã lia?" Le ema ta la, woate ŋu aɖo wò ɖe ahɔhɔ̃mekawo ƒe dɔwɔwɔ ŋuti nunyala bibi aɖe be woado wò kpɔ.
Wɔ nuku!
Le go bubu me la, numekuku aɖewo ɖee fia be statin zazã ate ŋu aɖe tagbɔdɔléle ƒe afɔkua dzi akpɔtɔ , alo nunya kple ŋkuɖoɖonudzi ƒe ɖiɖi si dzɔna ne ame tsi. Numekuku aɖe si wowɔ le ƒe 12 me ɖee fia be amesiwo noa statin ƒe agbɔsɔsɔ gã la ƒe tagbɔdɔléle ƒe afɔkua mebɔ o. Eyata wole numekuku geɖe wɔm tso esia ŋu.
Nukae wòle be nàwɔ ne èkpɔ nugbegblẽ le ame ŋu siawo?
Ne èle statin nom eye nèkpɔ ‘ahɔhɔ̃ me fuɖename’, lãmekawo ƒe vevesese, alo dzesi bubu ɖesiaɖe si mebɔ o la, nu vevitɔ kekeake kple nu ɖeka si wòle be nàwɔe nye be nàna wò ɖɔkta nanya.
Mègadzudzɔ wò atikewo nono kpata gbeɖe ne mèƒo nu kple wò ɖɔkta o. Ðo ŋku edzi be atike siawo kpɔa tawò tso afɔku sesẽwo abe dzidɔ kple ʋusɔgbɔdɔ ene me.
Wò ɖɔkta ada wò nɔnɔmea kpɔ eye wòatrɔ wò atikewɔwɔ ƒe ɖoɖoa ne ehiã. Ate ŋu awɔ nu siwo gbɔna:
- Statin-tike si nèzãna fifia la dzudzɔ hena ɣeyiɣi aɖe.
- Trɔtrɔ ɖe statin ƒomevi bubu ŋu.
- Atikewo ƒe agbɔsɔsɔ dzi ɖeɖe kpɔtɔ.
Nukawoe nye atike siwo woate ŋu azã ɖe statin teƒe?
Le go aɖewo me la, ne statin yi edzi le nugbegblẽ le ame ŋu hem vɛ la, wò ɖɔkta ate ŋu aɖo aɖaŋu na wò be nàzã atike bubuwo. Woŋlɔ amesiawo dometɔ aɖewo ɖe ete.
| Atikewo ƒe hatsotso | Dɔwɔwɔ ƒe ŋutete | Kpɔɖeŋuwo (adzɔnu ƒe ŋkɔwo) . |
|---|---|---|
| ACL Mɔxenuwo | Eɖea ʋumemi si aklãa wɔna dzi kpɔtɔna. Atike aɖewo hã xea mɔ na ʋumemi ƒe xɔxɔ tso dɔgbo suea me. | Nexletol (bempedoic acid), Nexlizet (bempedoic acid kple ezetimibe) . |
| PCSK9 Mɔxenuwo | Esiawo nye atike siwo wodona ɖe lãme na ame. Womegena ɖe ahɔhɔ̃a me o. Wogbãa LDL ʋumemi gbegblẽ si le ʋua me eye wònana woɖenɛ kabakaba. | Alirocumab (Atike si naa nuɖuɖu), Evolocumab (Repatha) . |
Atike siawo ate ŋu axɔ asi wu statin eye ɖewohĩ womasɔ na amesiame o, eyata nyametsotso si wò ɖɔkta awɔe nye esia.
Nukae wòle be nànya ne èle statin zãm?
Be nàɖe nugbegblẽ le ame ŋu dzi akpɔtɔ la, lé be na nya siawo hã:
- Kpɔ nyuie le weintsetse ŋu: Atike aɖewo siwo le weintsetse me tsi me ate ŋu ado kplamatse ŋutilãa ƒe ŋutete be wòagbã statin-tikewo. Mehiã be nàdzudzɔ weintsetse ɖuɖu kura o, gake bia wò ɖɔkta agbɔsɔsɔme si nàte ŋu aɖu/ano.
- Gblɔ atike bubu siwo katã nènona na wò ɖɔkta : Atike aɖewo ate ŋu awɔ dɔ kple statin eye woahe kuxiwo vɛ. Kpɔɖeŋuwo:
- Atike siwo wozãna na dzi ƒe tsotso ƒe kuxiwo (e.g. Amiodarone) .
- Atike bubu siwo me ʋumemi le (e.g., Gemfibrozil) .
- Atike siwo wozãna tsɔ daa HIV dɔlékuia
- Dɔlékuiwutike aɖewo kple dɔlékuiwutike aɖewo (e.g. Clarithromycin, Itraconazole) .
- Atike siwo tsia dɔlélenutsiŋutete nu (e.g. Cyclosporine) .
- Kpɔ nyuie le kamedede ŋu: Statin ƒe nugbegblẽ le ame ŋu si bɔ enye lãmekawo ƒe vevesese. Ne èdze kamedede sesẽwo wɔwɔ gɔme zi ɖeka esime nèle wo dzi la, àte ŋu adzi wò lãmekawo ƒe gbegblẽ ƒe afɔkua ɖe edzi. Ne ènye ame yeye le kamedede me la, ke tu ŋusẽa ɖo vivivi.
Gbedasi si Wotsɔ Yi Aƒeme
- Statin nye atike vevi aɖe ŋutɔ, si xɔa ame ɖe agbe, si ɖea dzidɔ kple ʋusɔgbɔdɔ ƒe afɔkua dzi kpɔtɔna.
- ‘Ahɔhɔ̃ me fuɖename’ nye nugbegblẽ le ame ŋu si mebɔ kura o. Zi geɖe la, mesẽna o eye wòdzona ne wodzudzɔ atikeawo zazã alo wotrɔe.
- Anɔ eme be nu bubuwo (ƒexɔxɔ, atikewɔwɔ ƒe nɔnɔme bubuwo) gbɔe ŋkuɖoɖonudzi ƒe kuxi siwo me tom nèle la tsona wu statin-tikewo zazã.
- Ne èkpɔ nugbegblẽ aɖewo la, nu nyuitɔ si nàwɔe nye be nàƒo nu kple wò ɖɔkta.
- Mègadzudzɔ statin nono le susu aɖeke ta atikewɔlawo ƒe aɖaŋuɖoɖo manɔmee o. Viɖe siwo dona tso eme la ƒo afɔku siwo le eme ta sãsãsã.
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