Menene calcitonin? Bari mu koyi game da shi a sauƙaƙe!

Shin kun taɓa jin kalmar calcitonin? Wataƙila kun ji ta ne daga likita, ko kuma wataƙila kun karanta ta a wani wuri. Wannan ainihin hormone ne na musamman a jikinmu. Amma kuma ana iya cewa wani irin hormone ne mai ban mamaki. Bari mu ga menene wannan calcitonin da kuma abin da yake yi wa jikinmu ta hanya mai sauƙi.

Menene calcitonin? Daga ina yake fitowa?

A taƙaice dai, calcitonin wani sinadari ne da glandar thyroid ɗinmu ke samarwa. Kun san cewa glandar thyroid ƙaramin siffa ce ta malam buɗe ido da ke gaban wuyanmu, a ƙarƙashin fata. Wani nau'in ƙwayar halitta na musamman a cikin glandar thyroid, wanda ake kira C-cells ko parafollicular cells, yana yin wannan hormone na calcitonin kuma yana sake shi cikin jininmu.

Amma abin mamaki shine, masana kimiyya har yanzu ba su fahimci ainihin aikin wannan hormone ba, calcitonin. Wato, mun san abin da yake yi, amma ba mu san ainihin dalilin da yasa muke da shi ba. Ko da akwai rashin daidaituwa a cikin matakan calcitonin, ba kasafai suke haifar da wata babbar alama ba, ko kuma wani lokacin babu komai.

A da, likitoci suna amfani da nau'ikan calcitonin na roba a matsayin magani ga wasu cututtuka. Misali, don magance cututtuka kamar cutar Paget ta ƙashi, ko hypercalcemia, yanayin da sinadarin calcium a cikin jini ya yi yawa. Amma yanzu, tare da zuwan sabbin magunguna, musamman bisphosphonates, ba kasafai ake amfani da calcitonin a matsayin magani ba.

Me calcitonin ke yi wa jikinmu?

Babban aikin sinadarin calcitonin shine rage yawan sinadarin calcium a cikin jininmu. Ku tuna, wannan yana magana ne game da sinadarin calcium a cikin jini, ba sinadarin calcium a cikin ƙashi ba. Yana yin hakan ta hanyoyi biyu:

1. Yana dakatar da ayyukan ƙwayoyin da ke ɗauke da ƙashi: Akwai wani nau'in ƙwayar halitta da ake kira osteoclasts a cikin ƙasusuwanmu. Waɗannan ƙwayoyin suna karya ƙasusuwanmu kuma suna ƙara calcium a cikin jini. Hormone na calcitonin yana dakatar da ayyukan waɗannan osteoclasts na ɗan lokaci. Wannan yana rage adadin calcium da aka ƙara a cikin jini.

2. Yana rage sake shan sinadarin calcium daga kodan zuwa jini: Ana fitar da sinadarin calcium tare da fitsarin da kodanmu suka tace. Duk da haka, wasu sinadarin calcium suna sake shiga jini ta hanyar kodan. Sinadarin calcitonin yana rage sake shan sinadarin calcium daga kodan zuwa jini ta wannan hanyar. Saboda haka, matakin sinadarin calcium a cikin jini yana raguwa.

Ka yi tunanin haka: matakin sinadarin calcium a cikin jininmu yana kama da matakin ruwan da ke cikin tankin ruwa. Calcitonin kamar wanda ke taimakawa wajen rage wannan matakin ruwan idan ya tashi.

Me yasa thyroid ɗinmu ke samar da calcitonin?

Glandar thyroid ɗinmu tana samar da calcitonin bisa ga matakin calcium a cikin jininmu. Lokacin da matakin calcium a cikin jini ya ƙaru, glandar thyroid tana samar da ƙarin calcitonin. Hakazalika, lokacin da matakin calcium a cikin jini ya ragu, adadin calcitonin da glandar thyroid ke samarwa shi ma yana raguwa. Wannan kamar sarrafawa ne ta atomatik.

Yadda ake duba matakan calcitonin? Me yasa ake yin wannan gwajin?

Likitanka zai iya yin gwajin jini don duba matakan calcitonin ɗinka.

Duk da haka, saboda rashin daidaituwar matakan calcitonin ba yawanci yakan haifar da manyan alamu ba, likitoci yawanci suna yin wannan gwajin ne kawai saboda wasu dalilai na musamman. Waɗannan sun haɗa da:

• Don taimakawa wajen gano cututtuka kamar Ciwon daji na Thyroid (MTC) ko C-cell hyperplasia .
• Kula da nasarar jiyya don ciwon daji na thyroid medullary (MTC).
• Idan wani a cikin iyalinka yana da wata cuta da ake kira Multiple Endocrine Neoplasia (MEN type 2) .

Menene matakin calcitonin na yau da kullun?

Gabaɗaya, ƙimar al'ada don calcitonin sune kamar haka:

• Ga maza: Kasa da picogram 25 a kowace millilita (Ƙasa da 25 pg/mL)
• Ga mata: Kasa da picogram 20 a kowace millilita (Ƙasa da 20 pg/mL)

Amma abu ɗaya da za a tuna shi ne cewa waɗannan dabi'un na yau da kullun na iya bambanta kaɗan daga dakin gwaje-gwaje zuwa dakin gwaje-gwaje. Saboda haka, ya kamata koyaushe ku duba dabi'un da aka saba amfani da su na dakin gwaje-gwaje a cikin rahoton jinin ku.

Idan aka yi maka gwajin calcitonin, likitanka zai yi maka bayani game da sakamakon kuma ya gaya maka ko ana buƙatar ƙarin gwaji.

Me zai faru idan matakan calcitonin suka ƙaru?

Samun yawan sinadarin calcitonin ba shi da wani mummunan tasiri ga jikinmu. Kuma ba ya haifar da wata babbar illa. Duk da haka, yawan sinadarin calcitonin na iya zama alama ta cututtuka guda biyu masu matuƙar wahalar magani. Menene su?

1. Ciwon Kansa na Thyroid (MTC): Wannan nau'in ciwon daji ne da ba kasafai ake samu ba wanda ke faruwa a cikin glandar thyroid. Yana farawa ne daga ƙwayoyin C waɗanda ke samar da calcitonin. Wannan ciwon daji yana sa waɗannan ƙwayoyin su samar da calcitonin da yawa.

2. Hawan jini a cikin ƙwayoyin C:Wannan ba ciwon daji ba ne (ba ciwon daji ba ne). Amma abin da ke faruwa a cikin wannan shi ne ƙwayoyin C suna girma yadda ba a saba ba. Wannan ƙwayar tsoka mai girma na iya samar da calcitonin da yawa. Wani lokaci wannan yanayin, wanda ake kira C-cell hyperplasia, daga baya zai iya zama ciwon thyroid medullary (MTC).

Idan kana da alamun ɗayan waɗannan yanayi, likitanka zai iya ba da shawarar a yi maka gwajin calcitonin.

Me zai faru idan matakan calcitonin suka ragu?

Da alama ƙarancin sinadarin calcitonin ba shi da wani tasiri sosai ga jikinmu. Har ma mutanen da aka cire musu sinadarin thyroid gaba ɗaya, saboda haka suna da sinadarin calcitonin da ba a iya ganowa ba, ba sa fuskantar wata alama da ke da alaƙa da matakin sinadarin calcium a cikin jininsu. Wannan abin mamaki ne game da wannan sinadarin hormone.

Mene ne bambanci tsakanin Calcitonin da Parathyroid Hormone?

Hormones na Parathyroid (PTH) da Calcitonin duk suna taimakawa wajen daidaita matakin calcium a cikin jininmu. Duk da haka, bambancin yana cikin yadda suke aiki da kuma yadda suke shafar matakan calcium ɗinmu.

• Hormone na Parathyroid (PTH) yana ƙara yawan sinadarin calcium a cikin jininmu. PTH kuma yana taimakawa wajen daidaita matakin phosphorus a cikin jininmu da ƙasusuwanmu. Yana kuma kunna bitamin D.
• Calcitonin yana rage yawan sinadarin calcium a cikin jininmu.

Duk da haka, masana kimiyya sun yi imanin cewa hormone na parathyroid (PTH) yana taka muhimmiyar rawa fiye da calcitonin wajen daidaita matakin calcium a cikin jininmu. Wannan ya faru ne saboda rashin daidaituwar matakan PTH na iya haifar da mummunan yanayi kamar hypercalcemia (ƙaruwar calcium a cikin jini) ko hypocalcemia (ƙarancin calcium a cikin jini). Duk da haka, matakan calcitonin marasa kyau ba su da wani tasiri mai mahimmanci ga jiki.

Shin calcitonin da calcitriol iri ɗaya ne?

A'a, calcitonin da calcitriol abubuwa ne daban-daban. Duk da cewa dukkan hormones ɗin suna shafar matakan calcium, suna da ayyuka daban-daban.

• Calcitriol wani suna ne na bitamin D mai aiki. Yana ƙara yawan sinadarin calcium a cikin jini. Ta yaya yake yin hakan? Yana ƙara yawan sinadarin calcium da za a iya sha a cikin hanjinmu daga abincin da muke ci. Wannan sinadarin calcium yana shiga jini. Calcitriol kuma yana hana kodan rasa sinadarin calcium. Hormone na Parathyroid (PTH) yana ƙarfafa enzyme wanda ke canza bitamin D zuwa calcitriol.
• Calcitonin yana aiki ta hanyar rage yawan sinadarin calcium a cikin jini.

Don haka, a ƙarshe, abubuwan da muke buƙatar tunawa (Saƙon Ɗauka Gida)

Calcitonin wani hormone ne mai ban mamaki da ban mamaki.

• Ko matakin yana ƙasa ko sama, da wuya ya haifar da wata babbar illa ko alamu.
• Duk da haka, ƙaruwar matakan calcitonin na iya zama alamar wata cuta kamar ciwon daji na thyroid medullary (MTC) ko kuma C-cell hyperplasia.
• Idan kana da alamun waɗannan yanayi, ko kuma kana da tambayoyi game da haɗarin kamuwa da su, ka tabbata ka yi magana da likitanka. Suna nan don taimaka maka. Kada ka firgita, abu mafi mahimmanci shine ka bayyana komai dalla-dalla.

Shin ka fahimta? Ina fatan wannan bayanin zai amfane ka.

Calcitonin , Calcitonin, Thyroid, Hormone, Calcium, Calcium na jini, Ciwon daji na Thyroid Medullary