Loaʻa iā ʻoe nā ʻulaʻula e like me ke kakalaioa i loko o kou koko? E aʻo kākou e pili ana i (Acanthocytosis)!

Ua lohe paha ʻoe i nā hunaola koko ʻulaʻula i loko o kou koko? ʻO ka maʻamau, he poepoe lākou, e like me nā pōpō liʻiliʻi pālahalaha. Akā i kekahi manawa, hiki i kēia mau hunaola koko ʻulaʻula ke hoʻololi i ke ʻano a loaʻa i kahi ʻano ʻē, ʻoi, a ʻoi. ʻO ia ka huaʻōlelo lapaʻau no kēia maʻi i kapa ʻia ʻo `(Acanthocytosis)`. E noʻonoʻo wale, ʻo ka huaʻōlelo Helene "acan" ʻo ia hoʻi he ʻoi, kahi mea e like me ke ʻoi. ʻO "Cyte" ʻo ia hoʻi he cell. No laila, ʻo "nā hunaola e like me ke ʻoi" ke ʻano maʻalahi o kēia.

ʻOiaʻiʻo, loaʻa iā kākou āpau kekahi o kēia mau ʻōpuʻu ʻoʻoi (Acanthocytes) i loko o ko kākou koko. ʻAʻole ia he pilikia nui. Akā, inā he nui loa kēia mau ʻōpuʻu ʻoʻoi i loko o kou koko, ʻo ia ka manawa e hoʻomaka ai kekahi mau pilikia liʻiliʻi e kū mai. Ua ʻike anei ʻoe i ka mea e hana ʻia? Loaʻa iā kākou kahi ʻōkana i kapa ʻia ʻo ka spleen . Hana ia e like me ke kānana e hoʻomaʻemaʻe i ko kākou koko. ʻO ka hana a ka spleen, ʻo ia ke ʻike i nā ʻōpuʻu kahiko a hōʻino ʻia i loko o ke koko a luku iā lākou. No laila, i ka wā e hele ai kēlā mau ʻōpuʻu koko ʻulaʻula ʻoʻoi ma o ka spleen, manaʻo ka spleen, "Auē, he ʻano palaka iki kēia, ʻaʻole like lākou me nā ʻōpuʻu maʻamau." A laila hoʻomaka ka spleen e luku i kēia mau ʻōpuʻu ʻoʻoi me ka wikiwiki. Ke hana ʻia kēlā, hiki ke emi ka helu o nā ʻōpuʻu koko ʻulaʻula olakino i loko o kou kino. Ua kapa ʻia kēia he anemia a i ʻole "hemolytic anemia". ʻO ia hoʻi, ka nele o ke koko i hana ʻia e ka haki ʻana o nā ʻōpuʻu koko ʻulaʻula. ʻAʻole wale ia, hiki i kēia kūlana i kapa ʻia ʻo "Acanthocytosis" ke lilo i hōʻailona o kekahi mau maʻi a me nā pilikia ʻē aʻe. No laila, ke loaʻa kēia mau hunaola ʻoʻoi i loko o ke koko, hiki iā ia ke kōkua i nā kauka e ʻike i nā maʻi ʻē aʻe.

No laila, he aha ke ʻano o nā hōʻailona e hiki iā mākou ke loaʻa ma muli o kēia `(Acanthocytosis)`?

Ke hoʻopau koke kou spleen i nā hunaola koko ʻulaʻula ma muli o ka maʻi sickle cell, e kū mai kahi kūlana i kapa ʻia ʻo "hemolytic anemia". Hiki iā ʻoe ke ʻike i nā hōʻailona e like me:

• Melemele o ka ʻili a me nā maka: Kāhea mākou i kēia he "jaundice", e like me ka mea e hana ʻia ke loaʻa i kekahi poʻe ke kuni melemele.
• Manaʻo luhi loa: ʻAʻole wale ka luhi, akā, he manaʻo o ka luhi loa me ka nānā ʻole i ka nui o ka hiamoe āu e loaʻa ai.
• Paʻakikī ka hanu ʻana: Manaʻo i ka pōkole o ka hanu ʻoiai me ka hoʻoikaika iki (dyspnea).
• Puʻuwai wikiwiki: He manaʻo o kou umauma e kuʻi wikiwiki loa ana ʻoiai ʻoe e kū mālie ana (tachycardia).
• Koko i loko o ka mimi: I kekahi manawa hiki i ka mimi ke lilo i ʻulaʻula a ʻeleʻele paha (hematuria).
• ʻEha ʻōpū: Hoʻokumu pinepine ʻia kēia e ka ʻōpū pehu.

Ma waho aʻe o kēia mau hōʻailona, ​​hiki ke ʻike ʻia nā hōʻailona ʻē aʻe ma muli o ka maʻi kumu i hoʻokumu ai i kēia mau ʻāpana unahi i loko o kou kino. E noʻonoʻo, no kekahi poʻe:

• Pohō kaumaha: Inā he pēpē liʻiliʻi ʻoe, lohi paha ka ulu ʻana.
• Nā pilikia e hoʻonohonoho ana i ka hana ʻiʻo: E like me ka nalowale ʻana o ke kaulike (ataxia).
• Nā neʻe ʻana o nā ʻāpana o ke kino i hiki ʻole ke kāohi: no ka laʻana, ka ʻimo ʻana a i ʻole ka hoʻohuli ʻana i ka ʻāʻī (tics).
• Paʻakikī i ka noʻonoʻo a me ka hoʻomanaʻo ʻana: Manaʻo e lohi ana kou lolo (hōʻino ʻike).
• Nā pilikia hoʻoheheʻe ʻana.
• Nā ʻōpala maeʻele: Hiki ke hana kēia ke ʻeli pono ʻole ʻia nā momona (steatorrhea).
• Mimi ʻeleʻele.

Inā loaʻa iā ʻoe kekahi a ʻoi aku paha o kēia mau hōʻailona, ​​​​ʻoi aku ka maikaʻi o ka ʻike ʻana i ke kauka i ka wā hikiwawe loa.

No ke aha e hana ʻia ai kēia ʻano o nā hunaola ʻoi i loko o ko kākou koko? He aha nā kumu?

I ka ʻōlelo maʻalahi, ʻo ke kumu nui o ka `(Acanthocytosis)` ʻo ia ka hopena ma ka membrane cell waho o nā ʻulaʻula koko, ʻo ia hoʻi, ka `(cell membrane).` Hana ʻia kēia membrane cell me nā momona `(lipids)` a me nā protein . No laila, inā he maʻi a maʻi paha e hoʻopilikia i kēia mau ʻāpana koʻikoʻi, e loli ke ʻano poepoe maʻamau o nā ʻulaʻula koko a hoʻomaka lākou e lawe i kēlā ʻano kākalaioa.

ʻAʻole maʻalahi ke kānana ʻia kēia mau cell kumu i hoʻololi ʻia i ka wā e hele ai lākou ma o ka spleen. No laila, luku ka spleen iā lākou. I kekahi manawa, ma kahi o ka luku ʻana i kēia mau cell, hoʻopololei ka spleen i kekahi o ko lākou mau iwi kuamoʻo a hoʻihoʻi iā lākou i loko o ke koko. Ua kapa ʻia kēia mau cell kumu i hoʻololi ʻia he `(spur cells)`.

Eia kekahi o nā kumu nui o ka acanthocytosis:

• Maʻi akepaʻa koʻikoʻi: ʻO nā spur cells he hōʻailona pinepine ia o ka maʻi akepaʻa koʻikoʻi, i kekahi manawa he mea hoʻoweliweli i ke ola. Loaʻa i kekahi poʻe me ka maʻi akepaʻa kahi maʻi i kapa ʻia ʻo spur cell anemia (SPA). ʻO ke ʻano kēia, he mau spur cells ko lākou i loko o ko lākou koko, a he haʻahaʻa hoʻi ka nui o nā hunaola koko ʻulaʻula.
• ʻAbetalipoproteinemia: He maʻi laha ʻole kēia, he maʻi hoʻoilina. ʻO ia hoʻi, ua hoʻoilina ʻia mai nā mākua a i nā keiki. ʻO kēia maʻi ke kumu o ka hiki ʻole i ke kino ke omo pono i nā momona a me nā huaora momona-hoʻoheheʻe ʻia (nā huaora A, D, E, K).
• Neuroacanthocytosis: He maʻi hoʻoilina laha ʻole kēia. Hoʻokumu kēia i ka hiki ʻole ke kāohi i nā neʻe ʻana o ke kino. ʻO nā hiʻohiʻona e komo pū me ka chorea-acanthocytosis, McLeod syndrome, pantothenate-kinase associated neurodegeneration (PKAN), a me ka maʻi Huntington-like 2.

Ma waho aʻe o kēia mau kumu nui, hiki i kekahi mau kūlana ʻē aʻe ke hana i ka "Acanthocytosis":

• ʻO Anorexia nervosa kahi maʻi i hoʻokumu ʻia e ka nele o ka makemake.
• Ka emi ʻana o ka hana o ka thyroid gland (Hypothyroidism).
• ʻO ka maʻi Myelodysplastic kahi maʻi ʻiʻo iwi.
• Maʻi puʻupaʻa.
• Ka wehe ʻana i ka spleen (splenectomy) ma ke ʻoki kino.
• ʻO kekahi mau lāʻau lapaʻau (no ka laʻana, nā lāʻau hoʻohaʻahaʻa cholesterol e like me "statins").

Pehea e ʻike ai nā kauka i ka acanthocytosis?

Hiki i kāu kauka ke ʻike i ka acanthocytosis ma ka hana ʻana i kahi peripheral blood smear (PBS) . Pili kēia i ka lawe ʻana i kahi hāpana liʻiliʻi o kou koko a nānā iā ia ma lalo o kahi microscope. E hōʻike maopopo kēia i ke alo o kēia mau cell ʻano ʻē a ʻoi.

A laila, no ka ʻike pono ʻana i ke kumu o kēia mau cysts sebaceous, pono ʻoe e hana i kekahi mau hoʻokolohua koko hou aʻe. Eia nā mea:

• Helu koko piha (CBC)
• Nā hoʻāʻo hana ate
• Nā hoʻokolohua hana puʻupaʻa
• Nā hoʻāʻo hormone thyroid
• Hoʻāʻo pae momona koko `(Panel lipid)`
• Nā hoʻokolohua genetic: E nānā i nā hoʻololi genetic e pili ana i kekahi mau maʻi hoʻoilina.

Eia kekahi, hiki i kāu kauka ke ʻōlelo aku i nā hoʻokolohua e like me ke kiʻi ʻana i ke kiʻi e ʻike ai inā he pōʻino i nā ʻiʻo a i ʻole nā ​​​​​​ʻōpū i loko o kou kino.

He aha nā lāʻau lapaʻau no kēia?

ʻO ke ʻano o ka mālama ʻana no ka acanthocytosis e pili ana i ke kumu. I ka hapanui o nā hihia, ke mālama pono ʻia ke kūlana kumu, hoʻi nā hunaola koko ʻulaʻula i ka maʻamau.

E noʻonoʻo e pili ana i ia mea, ʻo nā lāʻau lapaʻau no nā maʻi akepaʻa a me nā kūlana e like me ka "Neuroacanthocytosis" ke kumu nui o ka kaohi ʻana i nā hōʻailona. He paʻakikī ke ho'ōla piha i kēia mau maʻi. E lilo lākou i mea ʻino i ka hala ʻana o ka manawa. Eia nō naʻe, i nā maʻi akepaʻa koʻikoʻi, aia kekahi mau hihia kahi ʻo ka hoʻoili akepaʻa wale nō ka lāʻau.

Inā loaʻa iā ʻoe kahi maʻi genetic i kapa ʻia ʻo abetalipoproteinemia, pono paha ʻoe e hōʻemi i kāu ʻai ʻana i nā momona maikaʻi ʻole a loaʻa nā calorie lawa. Pono paha ʻoe e lawe i nā mea hoʻohui huaora e hōʻoia i ka loaʻa ʻana o nā huaora lawa (A, D, E, K) e kūkulu i nā hunaola koko ʻulaʻula olakino.

Inā hoʻokumu ʻia ka acanthocytosis e ka anorexia a i ʻole hypothyroidism, e hoʻomaikaʻi pinepine ke kūlana ke mālama ʻia ke kūlana kumu. Eia kekahi, inā ua hoʻoholo ʻia he lāʻau lapaʻau ke kumu o ka acanthocytosis, e nalowale pinepine ke kūlana ke hoʻōki ʻia ka lāʻau.

Inā loaʻa iaʻu kēia maʻi, he aha kaʻu e manaʻo ai?

I kekahi mau hihia, hiki ke ho'ōla loa ʻia kahi maʻi i kapa ʻia ʻo acanthocytosis me ka lāʻau lapaʻau. ʻO ke ʻano kēia, hoʻi nā hunaola koko ʻulaʻula i ka maʻamau.

Eia nō naʻe, ʻo ka hapa nui o ka manawa, ʻo kāu hopena olakino e pili ana i ke kumu o ka ulu ʻana o kēia mau kelepa sebaceous a me ka wikiwiki o kou hoʻomaka ʻana i ka mālama ʻana no ia.

Eia kekahi laʻana, ʻo nā maʻi e like me `(Neuroacanthocytosis)` a me `(Abetalipoproteinemia)` hiki ke hōʻino i nā ʻiʻo o ke kino i ka wā lōʻihi. Eia nō naʻe, inā ʻike ʻia a mālama ʻia ka maʻi i ka wā mua,, hiki ke hoʻolohi i ka holomua o nā hōʻailona.

Ma keʻano laulā, inā loaʻa iā ʻoe ka `(Acanthocytosis)` me ka maʻi akepaʻa, hiki ke lilo i mea koʻikoʻi iki. Nui ka poʻe me ka `(spur cell anemia)` i ʻōlelo ʻia ma luna nei e make i loko o kekahi mau mahina. No laila, ʻo ke ala maikaʻi loa e ʻike ai e pili ana i kou kūlana mai ke kauka nāna ʻoe e mālama. E nānā ʻo ia i kou olakino holoʻokoʻa a me ke kumu o kēia mau spur cells, a wehewehe i ka mea e hana nei iā ʻoe.

Aia kekahi ala e pale aku ai i kēia `(Acanthocytosis)` mai ka hana ʻana?

ʻOiaʻiʻo, inā hana ʻia ka acanthocytosis e kahi maʻi genetic, ʻaʻohe ala e pale aku ai. No ka mea, he mea ia a mākou e hoʻoilina ai. Eia nō naʻe, aia nā mea hiki iā mākou ke hana e hōʻemi i ka pilikia o ka hoʻomohala ʻana i kēia maʻi ma muli o kekahi mau kumu ʻē aʻe.

• E hōʻalo a kaupalena paha i ka inu ʻona: Hiki i kēia ke kōkua i ka pale ʻana i nā maʻi akepaʻa e pili ana i ka waiʻona.
• E ʻai i nā meaʻai momona: Pono kou kino e loaʻa nā meaola kūpono e hana i nā hunaola koko ʻulaʻula. Inā makemake ʻoe i ke kōkua i ke koho ʻana i nā meaʻai kūpono nāu, e kūkākūkā me kahi meaʻai meaʻai.
• E kiʻi i ka lāʻau lapaʻau i ka wā mua: Hiki i kekahi mau maʻi e hoʻoulu ai i nā cysts sebaceous ke lilo koke i mea koʻikoʻi inā ʻaʻole mālama ʻia. No laila, he mea nui loa e ʻike i ke kauka i ka wā e ʻike ʻia ai nā hōʻailona, ​​​​e nānā i ke kūlana, a hoʻomaka i ka lāʻau lapaʻau.

Pehea wau e mālama ai i koʻu olakino?

ʻO ka mea nui loa, ʻo ia ka hahai ʻana i ka lāʻau lapaʻau i kauoha ʻia e kāu kauka no ke kūlana kumu i hoʻokumu ai i kāu acanthocytosis.

Inā loaʻa iā ʻoe kahi maʻi genetic i kapa ʻia ʻo acanthocytosis, e noʻonoʻo e kiʻi i ke aʻoaʻo genetic . Hiki i kahi kākāʻōlelo genetic ke aʻo iā ʻoe pehea e pili ai ke ʻano iā ʻoe a me kou ʻohana, a me ka hiki ke hoʻoili ʻoe i ka mutation genetic e hoʻoulu ai i kāu mau keiki.

He aha nā nīnau e pono iaʻu e nīnau aku i kaʻu kauka?

Ke hele ʻoe e ʻike i ke kauka, mai kānalua e nīnau i nā nīnau e like me kēia:

• Pono anei au e hopohopo e pili ana i ka loaʻa ʻana o kēia mau hunaola ʻoʻoi (Acanthocytes) i loko o koʻu koko?
• He aha nā hoʻokolohua ʻē aʻe e pono ai iaʻu e hana e ʻike ai i ke kumu o kēia?
• He aha ke ʻano o ka lāʻau lapaʻau āu e manaʻo ai noʻu?
• He aha nā hopena e hiki iaʻu ke manaʻo mai kēia mau lāʻau lapaʻau?
• Pono anei au e ʻike i kahi kākā'ōlelo genetic?

ʻO ka mea hope loa, pono wau e ʻōlelo... (Leka Lawe-Home)

Ke hōʻoia nā kauka iā ʻoe, nānā pū lākou i ke ʻano o kou mau hunaola koko ʻulaʻula. Inā ua ʻike ʻia ʻoe me ka `(Acanthocytosis),` ʻo ia hoʻi he mau hunaola koko ʻulaʻula ʻē aʻe kou i loko o kou koko. Mai hopohopo. I kekahi manawa, hiki i ka lāʻau lapaʻau ke hoʻihoʻi i kou mau hunaola koko ʻulaʻula i ka maʻamau. A i ʻole, hiki iā ia ke kōkua i ka kaohi ʻana i ka maʻi kumu. Eia naʻe, i kekahi manawa, ʻo ka loaʻa ʻana o nā acanthocytes i loko o kou koko he hōʻailona ia o kahi maʻi koʻikoʻi, e like me ka maʻi akepaʻa koʻikoʻi. No laila, ʻo kāu kauka ke kanaka maikaʻi loa e wehewehe pono i ke ʻano o ka loaʻa ʻana o ka `(Acanthocytosis)` i kou olakino. Inā hoʻolohe ʻoe i kāna ʻōlelo a hahai pololei i ka lāʻau lapaʻau, hiki ke kaohi pinepine ʻia ke kūlana.

ʻAcanthocytosis , Nā hunaola koko ʻulaʻula, Scutellaria, Spleen, Anemia, Maʻi akepaʻa