ʻO ke Ake Momona ʻOi loa o ka Hāpai Keiki (AFLP): He mea koʻikoʻi kēia, e makaʻala kākou!

Ua ʻike anei ʻoe i kekahi manawa hiki ke kū mai nā pilikia olakino i manaʻo ʻole ʻia i ka wā hāpai? I kēia lā e kamaʻilio mākou e pili ana i kahi maʻi koʻikoʻi e pono ke ʻike ʻia, ʻoiai inā he mea i manaʻo ʻole ʻia. ʻOiai ʻaʻole kēia e hana i ka hapa nui o ka poʻe, inā hana ia, pono ia e mālama koke ʻia.

He aha kēia mea i kapa ʻia ʻo ka maʻi akepaʻa momona (AFLP) i ka wā hāpai?

I ka ʻōlelo maʻalahi, he maʻi laha ʻole akā koʻikoʻi loa ka Acute Fatty Liver of Pregnancy (AFLP) . ʻO kēia ka wā e piha loa ai kou akepaʻa i ka momona i ka wā hāpai. Hiki i kēia ke alakaʻi i ka hāʻule ʻana o ke akepaʻa a me nā pilikia ʻē aʻe e hoʻoweliweli ana i ke ola. ʻO ka ʻoiaʻiʻo, ua manaʻo ʻia he pilikia olakino . Inā hana ʻia kēia, ʻo ka mea maikaʻi loa e hana ai, ʻo ia ka hānau ʻana i ka pēpē i ka hikiwawe loa.

Pehea ka maʻamau o ka AFLP?

Mai hopohopo, ʻaʻole kēia he mea maʻamau loa. ʻO kēia kūlana i kapa ʻia ʻo AFLP he mea kākaʻikahi loa ia. Ua ʻōlelo ʻia e hoʻopilikia wale ia i hoʻokahi i loko o 10,000 a 20,000 mau hāpai ʻana i kēlā me kēia makahiki. No laila, ʻaʻole ia he mea āu e ʻike pinepine ai.

He aha nā hōʻailona o ka AFLP? (E makaʻala i kēia mau mea)

Hoʻomaka pinepine ka AFLP i ka hopena o ke kolu o ka trimester o ka hāpai ʻana - ma kahi o 36 mau pule - a ʻike pinepine ʻia. Eia nō naʻe, hiki ke hana mua ʻia i kekahi manawa, a i ʻole a hiki i ka hānau ʻana o ka pēpē.

Aia kekahi mau hōʻailona i ʻike pinepine ʻia i kēia maʻi:

• Ka luaʻi a me ka luaʻi: ​​ʻOiai he mea maʻamau kēia i ka wā hāpai, hiki i kekahi manawa ke lilo i hōʻailona o ka AFLP.
• ʻEha ʻōpū: Loaʻa kēia ʻeha ma ka ʻaoʻao ʻākau o luna o ka ʻōpū.
• Luhi nui: ʻAʻole wale ka luhi, akā, he manaʻo o ka luhi nui.
• He manaʻo ʻoluʻolu ʻole i ke kino: He manaʻo ʻoluʻolu ʻole i ke kino, me he mea lā e ulu ana kahi maʻi.
• Anorexia: Ka nalowale ʻana o ka makemake a pau e ʻai.
• Ke make wai nui nei: ʻAʻole pili i ka nui o ka wai āu e inu ai, manaʻo mau ʻia ʻaʻole lawa.
• Jaundice: Huli kou ʻili a me nā keʻokeʻo o kou mau maka i melemele. He hōʻailona maopopo loa kēia.
• Ka huikau a i ʻole ka hiki ʻole ke noʻonoʻo: Paʻakikī i ka noʻonoʻo ʻana, me ka manaʻo hoʻomaha ʻole.

E hoʻomanaʻo, hiki i nā hōʻailona o ka AFLP ke like me nā maʻi ʻē aʻe. No laila he mea nui e kamaʻilio me kāu kauka e pili ana i nā hōʻailona ʻē aʻe āu e ʻike ai i ka wā hāpai. He pilikia olakino ka AFLP e pono ai ka mālama koke ʻana.

No ke aha e hana ʻia ai kēia AFLP? He aha ke kumu?

ʻAʻole maopopo loa i nā kānaka noiʻi ke kumu o ka AFLP. ʻO kekahi o nā hana nui o ko kākou akepaʻa, ʻo ia ka wāwahi ʻana i nā waikawa momona. I loko o ka AFLP, aia kahi pilikia me ka hiki o ke akepaʻa ke wāwahi i kēia mau waikawa momona, e hōʻiliʻili ai ka momona keu i loko o ke akepaʻa. A laila, paʻa kēia momona i loko o ke akepaʻa, e hoʻopilikia ana i ka hana maʻamau o ke akepaʻa. Hiki i kēia ke hoʻoweliweli i ke ola inā ʻaʻole mālama ʻia.

Aia kekahi pilina hoʻoilina? (hemahema LCHAD)

Ua hōʻike kekahi mau noiʻi he mana hoʻoilina ko ka AFLP. ʻO ia hoʻi, hiki ke kumu ʻia e ka hemahema o ka enzyme i kapa ʻia ʻo ka long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD) deficiency .

He maʻi laha ʻole kēia hemahema (LCHAD), (autosomal recessive) . I ka ʻōlelo maʻalahi, no ka hoʻoilina ʻana o kahi pēpē i kēia, pono nā mākua ʻelua e loaʻa i ka gene kūpono no ia. ʻAʻole hiki i kahi pēpē me ka hemahema (LCHAD) ke hoʻololi pono i nā waikawa momona. A laila komo kēia mau waikawa momona i ke koko o ka makuahine ma o ka placenta. Hiki i kēia ke hōʻiliʻili i ka momona i loko o ke akepaʻa o ka makuahine. E noʻonoʻo pehea ka hopena o ka loli o ka metabolism o ke kino o ka pēpē i ka makuahine!

He aha nā kumu pilikia no ka hoʻomohala ʻana i ka AFLP?

Ua ʻike mākou i kēia manawa he hiki ke hoʻoilina ʻia kēia maʻi, i kapa ʻia ʻo AFLP. ʻO ia hoʻi, hiki ke hoʻoilina ʻia mai nā mākua mai. Eia kekahi, aia kekahi mau kumu pilikia ʻē aʻe:

• Inā ʻo kēia kou hāpai mua ʻana.
• Inā ʻoe e kali ana i nā māhoe a ʻoi aku paha.
• Inā ʻoe e kali ana i kahi keikikāne.
• Inā he maʻi diabetes kou.
• Inā loaʻa iā ʻoe ka cholestasis intrahepatic o ka hāpai ʻana.
• Inā loaʻa iā ʻoe ka preeclampsia.
• Inā he momona ʻoe.

Akā, me kēia mau mea pilikia a pau, ʻaʻole hiki i kāu kauka ke wānana inā e loaʻa iā ʻoe ka AFLP. ʻAʻole ia he mea hiki iā ʻoe ke wānana a pale aku. ʻO ia ka mea e hopohopo iki ai.

He aha nā pilikia e hiki mai ana o ka AFLP? (Hiki ke lilo i mea weliweli)

Hiki i ka maʻi ʻaʻai momona koʻikoʻi (AFLP) i ka wā hāpai ke make . Aia ʻoe a me kāu pēpē i ka pilikia no nā pilikia like ʻole. ʻO kekahi o lākou:

• Ka hemahema o ke akepaʻa.
• Ka hāʻule ʻana o nā puʻupaʻa.
• Ka hāʻule ʻana o ka māmā.
• Ka maʻi ʻana.
• Ke kahe koko.

He mea weliweli ke lohe i kēia mau mea, ʻeā? ʻO ia ke kumu he mea nui e makaʻala i kēia kūlana.

Pehea e ʻike ai i ke kūlana o ka AFLP?

No ka mea hiki i ka AFLP ke hoʻopilikia i ka hana pono ʻole o ke kino,He mea nui e ʻike mua i ka maʻi a hoʻomaka koke i ka lāʻau lapaʻau. ʻO ka ʻike pololei loa he biopsy akepaʻa . ʻO kēia kahi e nānā ai kāu kauka i kou ʻiʻo akepaʻa ma lalo o kahi microscope. Eia naʻe, ʻaʻole palekana mau kēia e hana i ka wā hāpai. No laila, hiki i kāu kauka ke ʻike pinepine i ka AFLP ma muli o kāu mau hōʻailona a me ka mōʻaukala olakino.

He aha nā mea e nānā ai nā hoʻokolohua koko?

E kauoha aku kāu kauka i nā hoʻokolohua koko e nānā no ka AFLP. I kekahi manawa, kānalua paha kāu kauka i ka AFLP ma muli o nā hopena o nā hoʻokolohua koko hana akepaʻa . Hōʻike pinepine kēia mau hoʻokolohua i nā mea e like me:

• Nā enzymes akepaʻa i hoʻokiʻekiʻe ʻia.
• Nā pilikia me kāu kaʻina hana koko.
• Hoʻonui ʻia ka nui o ka ammonia, ka waikawa uric, a me ka protein i loko o ke koko.
• Haʻahaʻa ke kō koko.
• Nā hōʻailona o ka hōʻino ʻia ʻana o nā puʻupaʻa.

Nā hoʻokolohua ʻē aʻe

No ka hōʻoia ʻana i ka maʻi, hiki i kāu kauka ke kauoha i kahi ultrasound scan a i ʻole kahi CT scan . Hiki i kēia ke hāʻawi i nā kiʻi kikoʻī o ke akepaʻa.

Pehea e mālama ʻia ai ka AFLP? (He mea nui ka mālama wikiwiki!)

I mea e pale aku ai i nā pilikia e hoʻoweliweli i ke ola, e ʻōlelo aku kāu kauka e hānau koke ʻoe i kāu pēpē . Ma hope o ka wehe ʻia ʻana o ke pēpē a me ka placenta, e hoʻomaka mālie kou akepaʻa e hoʻōla. ʻO kēia ka lāʻau nui a me ka lāʻau wale nō no kēia maʻi.

Aia kekahi mea e hiki iaʻu ke hana e hōʻemi i koʻu pilikia o ka AFLP?

He pilikia kēia i loaʻa i nā poʻe he nui. He maʻi laha ʻole ka AFLP. A, ʻaʻohe mea hiki iā ʻoe ke hana e pale aku ai a ʻike mua paha . ʻO kēia ka ʻāpana pōʻino o kēia maʻi.

He aha ka mea e hana inā loaʻa iaʻu ka AFLP?

Inā loaʻa iā ʻoe ka AFLP, pono ʻoe e hānau koke i kāu pēpē . E hoʻomaka ana ka hana o kou akepaʻa e hoʻi i ka maʻamau i loko o 10 mau lā ma hope o ka hānau ʻana. Pono ʻoe e nānā ʻia e nā kauka o ka haukapila a hiki i ka hoʻi ʻana o nā hopena hoʻāʻo o kou akepaʻa i ka maʻamau.

ʻAʻole hiki ke ʻōlelo pololei i kou pilikia no ka hoʻomohala hou ʻana o ka AFLP. Hiki i kāu kauka ke ʻōlelo aku i ka hoʻāʻo genetic e ʻike inā he mau ʻano ʻē i loko o nā waikawa momona i hiki ke kōkua i ka hoʻomohala ʻana o ka AFLP. Hiki iā lākou ke aʻo aku inā e hāpai hou ʻoe i ka wā e hiki mai ana, pono e nānā ʻia kou hāpai ʻana e kahi loea lapaʻau makuahine-keiki .

He aha ka pilikia o ka pēpē?

ʻO ke koʻikoʻi o ke kūlana i ka makuahine ka mea e hoʻoholo pinepine ai i ka nui o kona hopena i ka pēpē. Loaʻa i kekahi mau pēpē ka pilikia o ka loaʻa ʻana o kahi kūlana i kapa ʻia ʻo nonketotic hypoglycemia (ka hiki ʻole ke hana pono i nā waikawa amino). Hiki i kekahi ke loaʻa nā kūlana e like me ka dilated cardiomyopathy (kahi ʻiʻo puʻuwai nāwaliwali) a i ʻole neuropathy (hōʻino ʻia nā aʻalolo). Eia nō naʻe, i ka hapanui o nā hihia, ʻoi aku ka liʻiliʻi o ka pilikia i ka pēpē ma mua o ka pilikia i ka makuahine.

I ka manawa hea e pono ai iaʻu ke ʻike i ke kauka?

He mea nui e kaʻana like i kāu mōʻaukala olakino piha me kāu kauka i ka wā hāpai a e hoʻomaopopo iā lākou e pili ana i nā hōʻailona āu e ʻike nei. ʻO ka ʻoiaʻiʻo e kōkua iā ʻoe e loaʻa ka mālama olakino maikaʻi loa āu e pono ai.

Inā ʻike ʻoe i kekahi o kēia mau hōʻailona i ka wā hāpai, e ʻike koke i ke kauka :

• ʻEha ʻōpū a ʻeha pelvic paha e mau ana.
• Luhi nui a malaise paha.
• Ka luaʻi mau ʻana a me ka luaʻi ʻana.
• He ʻeha poʻo e nalowale mau ana.

He mau hōʻailona maʻamau paha kēia o ka hāpai ʻana, akā hiki nō hoʻi ke lilo i hōʻailona o kahi mea koʻikoʻi. No laila, mai kānalua.

He aha nā nīnau e pono iaʻu e nīnau aku i kaʻu kauka?

E noʻonoʻo, inā haʻi aku kāu kauka iā ʻoe he AFLP kou... he mea maʻamau iā ʻoe ke loaʻa nā nīnau he nui. Makemake paha ʻoe e nīnau iā ʻoe iho e like me:

• "E ke kauka, pono anei au e hānau i ke pēpē i kēia manawa?"
• "Aia anei koʻu ola i ka pilikia?"
• "Aia anei ke ola o kaʻu pēpē i ka pilikia?"
• "E ʻoi aku ka maikaʻi o kēia kūlana AFLP?"
• "He aha ke ʻano o ka lāʻau lapaʻau e pono ai iaʻu?"
• "E hana hou anei kēia inā e hāpai hou au?"
• "No ke aha i hiki mai ai kēia iaʻu, e ke kauka?"

E nīnau i nā nīnau a pau āu e noʻonoʻo ai penei. Mai hūnā i kekahi mea.

He aha ka ʻokoʻa ma waena o ka AFLP a me ka HELLP syndrome?

ʻO ka maʻi HELLP ( Hemolysis, Elevated Liver Enzymes, a me Low Platelet Count Syndrome)** he maʻi ia e kū mai ana i ka wā hāpai a ua like ia me ka AFLP. ʻO ka ʻokoʻa nui ma waena o nā maʻi ʻelua pehea e loli ai nā hopena o ka hoʻāʻo koko i ka hala ʻana o ka manawa. Pili pinepine ka AFLP i nā pilikia me ke kāpili ʻana o ke koko a me nā loli i nā pae platelet. Eia nō naʻe, pili pinepine ka maʻi HELLP i ka emi mālie ʻana o ka helu platelet.

Eia kekahi, ʻoi aku ka nui o ka poʻe me AFLP e ʻike i:

• Nā ʻano ʻino koʻikoʻi i nā hoʻokolohua hana ate.
• ʻO nā ʻano ʻē aʻe i ke kō koko.
• Nā hōʻailona o nā ʻano ʻē i ka hana o nā puʻupaʻa.
• Nā pae bilirubin kiʻekiʻe (he huahana ʻōpala ka bilirubin) i nā hoʻokolohua.
• ʻAcidosis (hoʻonui ʻia ka acidity o ke koko).
• (Proteinuria)(Aia ka protein i loko o ka mimi).
• Nā loli i ka hana o ka lolo (e.g., hiki ʻole ke noʻonoʻo pono, huikau).

He mea maʻamau anei ke loaʻa ʻana o ke akepaʻa momona i ka wā hāpai?

ʻOiai i loko o ka poʻe hāpai ʻole, he maʻi maʻamau ka maʻi akepaʻa momona a hiki ke mālama ʻia. Loaʻa i ka hapa nui o ka poʻe kekahi momona i loko o ko lākou akepaʻa. Eia nō naʻe, inā hōʻiliʻili kēia momona, hiki iā ia ke hana i ka hāʻule ʻana o ke akepaʻa. He mea weliweli loa kēia i ka wā hāpai , no ka mea, ʻo kou akepaʻa ke ala o ke kino e wehe ai i nā mea ʻawahia. Inā ʻaʻole hana pono kou akepaʻa (a i ʻole ke akepaʻa o kāu pēpē), hiki i nā mea ʻino ke hōʻiliʻili i loko o kou koko.

ʻO ka mea hope loa, eia kaʻu e ʻōlelo aku ai iā ʻoe (Leka Lawe-Home)

ʻO ka AFLP, a i ʻole ka maʻi momona momona o ka hāpai ʻana, he maʻi laha ʻole akā koʻikoʻi. ʻAʻole hiki ke pale ʻia a wānana ʻia paha. ʻO ke ʻano kēia he mea nui e kamaʻilio me kāu kauka e pili ana i kou mōʻaukala olakino a me nā hōʻailona ʻē aʻe āu e ʻike ai i kou wā hāpai. E kōkua kēia mau kūkākūkā i kāu kauka e ʻike i nā pilikia kūpono a hāʻawi iā ʻoe i ka mālama olakino āu e pono ai.

Mai hopohopo, akā e makaʻala . E makaʻala i kou kino. Inā manaʻo ʻoe i kekahi mea ʻē a ʻokoʻa paha, e ʻimi koke i ke kōkua lapaʻau. ʻO ka mea nui loa, ʻo ia ke olakino maikaʻi o ʻoe a me kāu pēpē.

ʻAke momona i ka wā hāpai, AFLP, nā pilikia hāpai, maʻi akepaʻa, jaundice, hānau keiki, hemahema LCHAD