Ua ʻike maoli anei ʻoe e pili ana i kēia hormone "rogue" i kapa ʻia ʻo Adiponectin?

Ua lohe mākou a pau e pili ana i nā ʻano hormones like ʻole i loko o ko mākou kino. Kamaʻilio mau mākou e pili ana i kekahi o lākou, a kamaʻilio pū nā kauka e pili ana iā lākou. Akā, ua lohe anei ʻoe i kahi hormone i kapa ʻia ʻo Adiponectin ? ʻAʻole paha ʻoe. Akā, he kuleana koʻikoʻi kona i loko o ko mākou kino, ʻoiai hoʻi i nā mea e like me ko mākou kaumaha a me nā pae kō koko. No laila, i kēia lā, e kamaʻilio kākou e pili ana iā Adiponectin ma ke ʻano maʻalahi a pololei.

He aha ka Adiponectin? He mea maʻalahi loa ia!

I ka ʻōlelo maʻalahi, ʻo ka adiponectin kahi hormone protein i hana nui ʻia e nā hunaola momona, a i ʻole nā ​​ʻiʻo adipose, i loko o ko kākou kino. Ua kapa ʻia hoʻi ia he adipokine , no ka mea, ua hana ʻia ia me ka momona. Eia naʻe, ʻaʻole wale ia e hana ʻia e nā hunaola momona, akā, ma kekahi mau ʻāpana ʻē aʻe o ko kākou kino.

Ua ʻike ʻia kēia kanaka i kapa ʻia ʻo Adiponectin i nā makahiki 1990. ʻO ia hoʻi, ke aʻo nui nei nā kānaka ʻepekema e pili ana i ia mea. Malia paha he mau mea ʻē aʻe a kēia hormone e hana ai ʻaʻole mākou i ʻike. I ko mākou ʻike ʻana, kōkua nui ia i ka hoʻonui ʻana i ka ʻike o ko mākou kino i ka insulin a me ka hōʻemi ʻana i ka mumū i loko o ke kino .

He aha nā pono o Adiponectin no ko mākou kino?

ʻO kēia hoaaloha i kapa ʻia ʻo Adiponectin ke komo nei i nā kaʻina hana koʻikoʻi he nui i loko o ko mākou kino. E nānā kākou i ʻelua o nā mea koʻikoʻi loa.

1. Pehea e hoʻomaopopo ai i ko mākou kino i ka insulin

ʻIke anei ʻoe i ke ʻano o ka insulin? I ka ʻōlelo maʻalahi, ua like ka insulin me ke kī e wehe ana i ka puka e ʻae i ke kō (glucose) i loko o nā ʻāpana o ko kākou kino. ʻO ke ʻano o ka maʻalahi i ka insulin , ʻo ia hoʻi, hiki i kēia kī ke wehe pono i ka puka. A laila hiki i ke kino ke hoʻohana maʻalahi i ke kō a mālama i nā pae kō koko ma ka pae kūpono.

No laila, penei ke kōkua ʻana o Adiponectin:

• Kōkua kou ʻiʻo iwi a me ke akepaʻa i kou kino e pane kūpono i ka insulin.
• Hoʻonui i ka hoʻokuʻu ʻana o ka insulin mai ka pancreas.
• Hoʻopau ia i ka mālama pono ʻole ʻia o ke kō i kapa ʻia ʻo glycogen i loko o ke ake.
• Kōkua ia i ka wāwahi ʻana i nā waikawa momona a hoʻokumu i ka ikehu.

E noʻonoʻo e pili ana i ia mea, ua like nā pūnaewele o kou kino me nā hale. ʻO ka insulin ka mea e lawe i ka meaʻai i kapa ʻia ʻo ke kō i kēlā mau hale. Kōkua ʻo Adiponectin i ka lawe ʻana mai i kēia meaʻai ma ka puka. A laila loaʻa i ka hale ka meaʻai, ʻeā?

2. Pehea e hōʻemi ai i ka mumū i loko o ke kino

ʻO ka mumū ka wā e hoʻouna ai kā mākou ʻōnaehana pale i nā pūnaewele e hakakā i kahi mea e like me ka bacteria a i ʻole e ho'ōla i kahi ʻeha. I kekahi manawa he mea pono kēia. Akā, ʻo ka mumū mau loa, ʻO ia hoʻi, ʻaʻole maikaʻi i ke kino ke loaʻa mau kahi mumū liʻiliʻi i loko. E noʻonoʻo ʻoe he ahi liʻiliʻi kou i loko o kou kino... ʻO ia ka mea i kapa ʻia ʻo ka mumū mau loa.

Kōkua ʻo Adiponectin i ka hōʻemi ʻana i ka mumū ma nā wahi aʻe:

• ʻO nā Macrophages (kahi ʻano koko keʻokeʻo e hoʻopuni a pepehi i nā mea e like me nā bacteria a me nā virus)
• ʻO ka ʻiʻo Endothelial (ʻo kēia nā pūnaewele e hana ana i kahi membrane lahilahi e uhi ana i loko o ka puʻuwai a me nā kīʻaha koko)
• Nā pūnaewele ʻiʻo
• Nā pūnaewele Epithelial (ʻo ia nā pūnaewele e uhi ana i nā ʻili āpau i loko a ma waho o ke kino)

Ma ka hōʻemi ʻana i ka mumū ma kēia ʻano, pale ʻo Adiponectin i kēia mau ʻōpū:

• ʻŌnaehana vascular
• Puʻuwai
• Nā māmā
• Kolon

Ma hea kahi i hana ʻia ai ʻo Adiponectin i loko o ko mākou kino?

Hana nui ʻia ʻo Adiponectin a hoʻokuʻu ʻia e nā pūnaewele i kapa ʻia ʻo adipocytes, nāna e mālama i ka ikehu i loko o ko kākou ʻiʻo adipose keʻokeʻo . ʻO ka ʻiʻo adipose keʻokeʻo ke ʻano nui o ka momona i loko o ko kākou kino. Loaʻa ia ma:

• ʻO ka momona ma lalo o ka ʻili - ʻo ia hoʻi, ka papa o ka momona a mākou e ʻike ai ke hoʻopā mākou iā ia.
• ʻO ka momona visceral - ʻO kēia ka momona i loko o ka ʻōpū hiki ke lilo i mea weliweli iki.
• ʻIwi momona (momona iwi)

Hiki ke hana ʻia ʻo Adiponectin e nā ʻano cell ʻē aʻe:

• Nā pūnaewele ʻiʻo iwi
• Nā pūnaewele ʻiʻo puʻuwai
• Nā pūnaewele endothelial

Pehea e kāohi ʻia ai nā pae adiponectin?

E like me kaʻu i ʻōlelo ai ma mua, he mea hou ka adiponectin. No laila ke noiʻi nei nā kānaka ʻepekema iā ia. A hiki i kēia manawa, ua ʻike ʻia kekahi mau hormones e kōkua i ka hoʻoponopono ʻana i nā pae adiponectin.

ʻOiai ke ʻano o ka hormone insulin e pili ana i kēia, ʻaʻole ʻae like nā kānaka a pau i ke ʻano o ka hana ʻana.

ʻO ka Insulin-like growth factor (IGF-1) a me ka growth hormone (GH) ke kāohi i ka hoʻokuʻu ʻia ʻana o ka adiponectin mai ka ʻiʻo momona. Hiki ke pili pū ʻia ʻo Leptin (kekahi hormone i hana ʻia e nā hunaola momona).

Pehea e nānā ai i nā pae adiponectin?

Hiki iā ʻoe ke nānā i kāu mau pae Adiponectin me kahi hoʻāʻo koko .

I kekahi manawa, huikau nā kauka i ka maʻi diabetes type 2 me ka metabolic syndrome.Hiki ke hoʻohana ʻia ka hoʻāʻo koko adiponectin e kōkua i ka ʻike ʻana i nā kūlana e like me:

Pehea ke ʻano o nā pae adiponectin maʻamau?

ʻOkoʻa nā pae maʻamau o ka adiponectin ma muli o kou kāne a me ke kino a me ka Body Mass Index (BMI) , ʻo ia kou kaumaha no kou kiʻekiʻe.

ʻO nā pae Adiponectin maʻamau no nā kāne penei:

• Inā emi ka BMI ma mua o 25: 5 a 37 micrograms/milliliter (5 a 37 ug/mL)
• Inā ma waena o 25 a me 30 ka BMI: 5 a 28 ug/mL
• Inā ʻoi aku ka BMI ma mua o 30: 2 a 20 ug/mL

ʻO nā pae Adiponectin maʻamau no nā wahine penei:

• Inā emi ka BMI ma mua o 25: 5 a 37 ug/mL
• Inā ma waena o 25 a me 30 ka BMI: 4 a 20 ug/mL
• Inā ʻoi aku ka BMI ma mua o 30: 4 a 22 ug/mL

ʻO ka mea nui, hiki ke ʻokoʻa iki kēia mau helu mai ke kanaka a ke kanaka a mai ka hale hana a i ka hale hana. No laila, e nānā i ka pae maʻamau ma kāu hōʻike hale hana. Inā he mau nīnau kāu e pili ana i kāu mau hopena, e ʻoluʻolu e nīnau i kāu kauka a kahu maʻi paha.

He aha nā maʻi e hiki ke ulu ke kū ʻole nā ​​​​pae adiponectin?

Aia kekahi mau kūlana olakino i pili i nā pae maʻamau ʻole o ka adiponectin. ʻO kēia mau mea:

• Ka momona a me ke kaumaha haʻahaʻa
• Ke kū'ē ʻana o ka insulin
• Atherosclerosis
• Lipodystrophy

Hoʻopili ʻia ka nui o kēia mau kūlana me nā pae haʻahaʻa o ka adiponectin .

ʻO Adiponectin a me ka momona

He haʻahaʻa nā pae o ka adiponectin o ka poʻe momona. Ma ka ʻaoʻao ʻē aʻe, ʻo ka poʻe wiwi loa, inā paha ma muli o nā kūlana e like me ka anorexia nervosa a i ʻole ka malnutrition, he kiʻekiʻe ko lākou mau pae o ka adiponectin.

I ka ʻōlelo maʻalahi, i ka piʻi ʻana o ka momona o ke kino o ke kanaka, e emi ana ko lākou pae adiponectin. Pēlā nō, i ka emi ʻana o ka momona o ke kino, e piʻi ana ko lākou pae adiponectin. Ke emi ke kaumaha o ke kanaka momona, e piʻi ana ko lākou pae adiponectin.

ʻO ke kū'ē ʻana o Adiponectin a me Insulin

Ma muli o ke kōkua ʻana o ka adiponectin i ka hoʻonui ʻana i ka ʻike o ka insulin, ʻo ka poʻe me ke kūʻē ʻana i ka insulin he haʻahaʻa loa ko lākou pae o ka adiponectin. ʻO ke kūʻē ʻana i ka insulin ka wā e pane pono ʻole ai nā ʻāpana o kou kino i ka insulin, e hoʻokuʻu ana kou kino i ka nui o ka insulin (hyperinsulinemia).

Ma muli o ke kū'ē'ē o ka insulinHiki ke ulu ka prediabetes, ka maʻi diabetes Type 2 , a me ka maʻi diabetes gestational . Hoʻopili pinepine ʻia kēia me ka momona. Eia nō naʻe, hiki i ka poʻe ʻaʻole momona ke hoʻomohala i ke kūʻē ʻana o ka insulin. ʻO ka mea kupanaha, ʻo ka poʻe i kūʻē i ka insulin me ka ʻole o ka momona he haʻahaʻa hoʻi o ka adiponectin. Hōʻike kēia aia kahi kumu genetic i pili i ke kūʻē ʻana o ka insulin a me ka adiponectin.

ʻO Adiponectin a me Atherosclerosis

ʻO Atherosclerosis kahi maʻi kahi e hōʻiliʻili ai ka plaque ma loko o kou mau aʻa, e ālai ana iā lākou. Ua like ia me ka ʻōpala e hōʻiliʻili ana i loko o kahi paipu wai.

Loaʻa i ka Adiponectin nā waiwai anti-inflammatory, nāna e pale i ka puʻuwai a me nā kīʻaha koko. No laila, ke haʻahaʻa nā pae adiponectin, hiki ke piʻi aʻe ka pilikia o ka loaʻa ʻana o nā maʻi puʻuwai e like me ka atherosclerosis a me nā hōʻeha puʻuwai .

ʻO Adiponectin a me Lipodystrophy

He maʻi laha ʻole ka Lipodystrophy e hoʻoulu ai i ka pohō momona ma kekahi mau wahi o ke kino a me ka hōʻiliʻili ʻana o ka momona keu i nā wahi ʻē aʻe.

Hiki ke loaʻa ka lipodystrophy mai ka wā hānau mai, a i ʻole hiki ke ulu aʻe ma hope o ke ola. Haʻahaʻa nā pae adiponectin i ka lipodystrophy hānau ʻia a me ka maʻi HIV . Malia paha kēia no ka mea pili ka adiponectin i ke ʻano o ka mālama ʻana i ka momona o ke kino.

Aia kekahi lāʻau lapaʻau no nā pae adiponectin maʻamau ʻole?

ʻO ka ʻoiaʻiʻo, aia nā lāʻau lapaʻau kūlohelohe e hiki ke kōkua i ka hoʻomaikaʻi ʻana i nā pae adiponectin. ʻO kēia mau mea e komo pū me ka hoʻoikaika kino mau a me ka pohō kaumaha olakino. Eia nō naʻe, pono ʻoe e kamaʻilio mau me kāu kauka ma mua o ka hana ʻana i kekahi mau hoʻololi nui i kāu papaʻai a i ʻole ka hana maʻamau.

Ua ʻike ʻia nā lāʻau lapaʻau maʻi diabetes e like me ka metformin a me ka thiazolidinediones e hoʻonui i nā pae adiponectin.

Ke noiʻi nei nā kānaka ʻepekema i nā lāʻau lapaʻau e hana like ana me Adiponectin e mālama i nā maʻi mumū mau loa. He nūhou maikaʻi paha kēlā no mākou i ka wā e hiki mai ana!

He aha ka ʻokoʻa ma waena o Adiponectin a me Leptin?

ʻO Leptin lāua ʻo Adiponectin he mau hormones i hana ʻia a hoʻokuʻu ʻia e kou ʻiʻo momona, kahi ʻano adipokines. Hana ʻo Leptin ma ka hoʻoikaika ʻana i ka metabolism a me ka hōʻemi ʻana i ka makemake.

E like me ka adiponectin, ua pili pū ʻia nā pae maʻamau ʻole o ka leptin me ka momona - akā ma ke ʻano ʻokoʻa. Piʻi ka pae Leptin i ka piʻi ʻana o ka momona o ke kino. Eia nō naʻe, emi ka pae adiponectin i ka piʻi ʻana o ka momona o ke kino. Maʻalahi e hoʻomanaʻo, ʻeā?

ʻO ka mea hope loa, ʻo ka mea nui loa

Ua maopopo paha iā ʻoe i kēia manawa ke koʻikoʻi o ka adiponectin i ko mākou kino. ʻOiai he mea hou ia, ke aʻo hou nei nā kānaka ʻepekema e pili ana i ia mea.

Inā loaʻa iā ʻoe kahi maʻi metabolic e like me ka momona a i ʻole ka maʻi diabetes type 2, ua lohe paha ʻoe i kāu kauka e kamaʻilio ana e pili ana i ka adiponectin. Inā he nīnau kāu e pili ana i kahi huaʻōlelo a kāu kauka e ʻōlelo ai, mai makaʻu e nīnau. Eia lākou e kōkua.

ʻAʻohe mea e hopohopo ai i ka wā e pili ana i kāu mau pae adiponectin. ʻO nā ʻano olakino maikaʻi, ka ʻai kaulike, a me ke ʻano ola kino nā ala maikaʻi loa e mālama ai i kēia mau pae hormone. No laila, e mālama i kou kino, no ka mea, ʻo ke olakino ka mea nui loa!

ʻAdiponectin , Adiponectin, Hormone, Insulin, Maʻi diabetes, Momona, Mumū, Metabolism, Nā Kelepona Momona