Ke ʻike nei ʻoe i nā loli i ke kino o kāu pēpē i ka wā mua? E kamaʻilio kākou e pili ana iā Adrenarche!

Ua hoʻomaka anei ʻoe e ʻike i kekahi mau loli i ke kino o kāu keiki liʻiliʻi, malia paha ma mua o kou manaʻo? I kekahi manawa, manaʻo paha ia e ulu ana kahi lauoho liʻiliʻi ma nā ʻauwae a i ʻole nā ​​​​​​ʻāpana pilikino, a i ʻole he ʻala hou? He mea maʻamau no ka makuahine a makua paha ke manaʻo iki i ka makaʻu a me ka hopohopo ke ʻike lākou i kēia mau mea. No laila i kēia lā, e kamaʻilio kākou e pili ana i kahi kaʻina hana kūlohelohe i kapa ʻia ʻo adrenarche, ʻo ia paha ke kumu o kēia.

Ua ʻike anei ʻoe i ke ʻano o Adrenarche?

I ka ʻōlelo maʻalahi, ʻo Adrenarche kahi hana kūlohelohe kahi e hoʻomaka ai nā kelepa adrenal o kāu keiki e hana i ka nui o ka hormone i kapa ʻia ʻo DHEA (Dehydroepiandrosterone). Hoʻomaka pinepine kēia ma waena o nā makahiki 6 a me 8. I mea e pololei ai, hana ʻia kēia ma kahi o ʻelua mau makahiki ma mua o ka hoʻomaka ʻana o ke keiki e hōʻike i nā hōʻailona o ka wā ʻōpio (pubarche).

E noʻonoʻo i kēia hormone DHEA ma ke ʻano he mea maka. Hoʻohana ko mākou kino iā ia e hana i nā hormones koʻikoʻi ʻē aʻe. No ka laʻana, hana ʻia nā hormones i loko o ka hui androgen (e like me ka testosterone a me ka androstenedione) a me ka hormone estrogen mai kēia DHEA. Kōkua kēia mau hormones androgen i ka hoʻomaka ʻana o ka wā ʻōpiopio, a he mea nui hoʻi no ke olakino hānau hou a me ka ulu ʻana o ke kino.

ʻO kekahi ʻano ʻē aʻe o DHEA i kapa ʻia ʻo DHEAS (Dehydroepiandrosterone-sulfate). ʻO kēia ke ʻano o DHEA e kaapuni ana i loko o ko kākou koko. Hiki i kahi hoʻāʻo koko ke ana i ka pae o DHEAS e hoʻoholo ai inā e hana ana ka hana adrenal. Eia naʻe, no ka mea he hana kūlohelohe kēia, ʻaʻole hana mau ʻia kēia hoʻāʻo koko ma nā keiki.

He aha ka mea e hana maoli ana i ka wā o ka adrenarche?

I ka wā o ka adrenarche, hoʻomaka ka ʻaoʻao o waho o nā kelepa adrenal o kāu pēpē, ʻo ia ka adrenal cortex, e ulu a oʻo.

ʻEkolu mau papa o kēia cortex adrenal:

• ʻO ka papa waho loa (zona glomerulosa)
• Zona fasciculata (papa waena)
• ʻO Zona reticularis (papa o loko loa). ʻO kēia ʻāpana, i kapa ʻia ʻo zona reticularis, ʻo ia ka ʻāpana i ulu nui loa i ka maʻi ʻaʻai adrenal.

I ka ulu ʻana o kēia, hana nā kelepa adrenal i ka DHEA, a laila hoʻololi ke kino i nā hormones androgen. ʻO kēia DHEA a me nā hormones āna e hana ai ka mea e hoʻomaka a hoʻonui paha i kēia mau mea:

• Nā kelepa sebaceous: ʻO kēia nā kelepa i loko o ko mākou ʻili e hana i kahi mea ʻaila (sebum). Kōkua kēia mea huna i ka ʻili e mālama i ka makū a hāʻawi i kahi uhi pale. Hoʻopilikia pū kā lākou hana i ka ʻala o ke kino.
• Nā kelepa Apocrine: He mau kelepa kūikawā kēia i loaʻa ma nā wahi e like me nā armpits a me ka ʻūhā. Noho lākou me ka hana ʻole a hiki i ka hoʻoulu ʻia ʻana e nā hormones adrenal i ka wā o ke kaʻina hana adrenal.
• ʻO ka lauoho pubic a me ke axillary:ʻO ka lauoho pubic kahi ʻano lauoho i ʻeleʻele iki a mānoanoa. Ma muli o ka hormone androgen e hoʻomaka ai ka lauoho axillary e ulu ma ka ʻāpana pubic a me nā armpits.

ʻO ka mea nui, ʻokoʻa kēia mau hormones adrenal mai nā hormones e hoʻonui ai i ka umauma a me nā genitalia kāne (i kapa ʻia ʻo gonadarche) i ka wā ʻōpio. ʻO Gonadarche ka hoʻonui ʻia ʻana o ka hana ʻana o nā hormones wahine nui (estrogen a testosterone paha) e nā ovaries a me nā testicles. Pono kēia mau ʻōpū a me nā hormones no ka hana hou ʻana i ka moekolohe. ʻAʻole pili pololei nā hormones adrenal.

ʻElua mau kaʻina hana kūʻokoʻa a kaʻawale ʻo Adrenarche a me gonadarche. ʻAʻole maopopo i nā kānaka noiʻi ka mea e hoʻoulu ai i ka adrenarche.

Pehea ka lōʻihi o ka noho ʻana o Adrenarche?

ʻO ka maʻamau, ʻelua mau makahiki ka lōʻihi o Adrenarche, a hiki i ka hoʻomaka ʻana o ka pubarche, ka hōʻailona mua o ka wā ʻōpio. Eia nō naʻe, hoʻomau nā kelepa adrenal o kāu keiki i ka hana ʻana i ka DHEA a hiki i ka wā makua. ʻOi aku ka kiʻekiʻe o nā pae DHEA i ka wā ʻōpio (ma kahi o 20-24 mau makahiki), a laila e emi mālie ana i kou wā ʻelemakule.

He aha nā hōʻailona o Adrenarche?

ʻO kaʻoiaʻiʻo, ʻaʻohe hōʻailona kino maopopo o ka adrenarche. ʻO ia hoʻi, i ka wā e piʻi mua ai nā pae DHEA, ʻaʻohe loli i ʻike ʻia ma ke kino o ke keiki e pili pono ana iā ia.

Eia nō naʻe, ma kahi o ʻelua mau makahiki ma hope o ka hoʻomaka ʻana o ka lawa ʻole o ka adrenal, hoʻomaka ka pubarche , a i ʻole ka lauoho pubic, e ʻike ʻia. Manaʻo nā kauka he hopena kino kēia o ka lawa ʻole o ka adrenal. Hōʻailona ʻo Pubarche i ka hoʻomaka ʻana o ka wā ʻōpio.

ʻO nā hiʻohiʻona ʻē aʻe o ka lauoho pubic:

• ʻO ke ʻano o ka lauoho axillary.
• ʻAla hou (ala kino / ʻala apocrine).
• Hoʻonui ʻia ka ʻaila o ka ʻili a me ka lauoho o ke keiki.
• ʻAkika.

I ka makahiki hea e hoʻomaka ai ka lauoho pubic e ʻike ʻia?

ʻOkoʻa iki kēia mai kekahi keiki a i kekahi keiki, ma muli o ke kāne a wahine paha, a ma muli hoʻi o ka lāhui a me ka lāhui. Eia kekahi laʻana, eia nā awelika makahiki e like me nā noiʻi i mālama ʻia ma ʻAmelika Hui Pū ʻIa:

• No nā kaikamahine ʻeleʻele ʻaʻole he Hispanic, ma kahi o 9.5 mau makahiki.
• No nā kaikamahine Mekiko-ʻAmelika, ma kahi o 10.3 mau makahiki.
• No nā kaikamahine keʻokeʻo ʻaʻole he Hispanic, ma kahi o 10.5 mau makahiki.
• No nā keikikāne ʻeleʻele ʻaʻole he Hispanic, ma kahi o 11.1 mau makahiki.
• No nā keikikāne Mekiko-ʻAmelika, ma kahi o 12.3 mau makahiki.
• No nā keikikāne keʻokeʻo ʻaʻole he Hispanic, ma kahi o 12 mau makahiki.

ʻO ka mea nui, ʻaʻole like nā keiki a pau, ulu ke kino o kēlā me kēia kanaka ma ko lākou ʻano ponoʻī. Hiki ke like kēia mau pae makahiki no nā keiki ma Sri Lanka, akā aia nā ʻokoʻa mai kekahi keiki a i kekahi keiki.Inā he mau nīnau a hopohopo paha kāu e pili ana i ka ulu ʻana o kāu keiki, ʻo ka mea maikaʻi loa e hana ai, ʻo ia ke kamaʻilio me kāu pediatrician.

He aha ka Adrenarche mua?

ʻO ka adrenarche mua ʻole ka wā e hoʻomaka ai nā mea e like me ka lauoho pubic a me ka armpit a me ka hanu ʻino ma mua o ka mea i manaʻo ʻia. ʻO ka maʻamau, ʻike ʻia kēia mau hōʻailona ma mua o 8 mau makahiki i nā kaikamahine a ma mua o 9 mau makahiki i nā keikikāne. He adrenarche mua paha kēia.

Ua kapa ʻia kēia he pubarche premature, no ka mea, ʻaʻohe o mākou ala e ʻike ai inā ua hoʻomaka mua ke kaʻina hana kūloko i kapa ʻia ʻo adrenarche, a hiki i ka wā e ʻike ʻia ai ka hōʻailona kino o ia mea, ʻo pubarche.

Ua hōʻike ʻia nā noiʻi he ʻeiwa manawa ka nui o ka loaʻa ʻana o kēia maʻi i nā kaikamahine ma mua o nā keikikāne. ʻAʻole i ʻike ʻia ke kumu pololei no kēia.

He aha nā hōʻailona o ka adrenarche mua?

ʻO nā hōʻailona nui o ka lawa ʻole o ka adrenal:

• ʻIke ʻia ka lauoho ma ka ʻāpana pubic a/a i ʻole nā ​​​​​​armpits ma mua o 8 mau makahiki no ke kaikamahine, a i ʻole ma mua o 9 mau makahiki no ke keikikāne.
• Hiki i ke ʻala o ke kino mai nā ʻūpā ke hoʻolilo i ka pono e hoʻohana i kahi mea e like me ka deodorant.

ʻOi aku ke kiʻekiʻe o nā keiki me kēia ʻano lawa ʻole o ka adrenal ma mua o nā poʻe ʻē aʻe i ko lākou mau makahiki, i kekahi manawa ʻoi aku ma mua o 90th percentile ma nā pakuhi kiʻekiʻe no ko lākou mau makahiki a me ke kāne.

Akā eia kekahi mea e hoʻomanaʻo ai: ʻAʻole ka wā ʻōpiopio mua ke kumu o ka ulu ʻana o ka umauma ma mua o ka manawa a i ʻole ka ulu ʻana o ka moekolohe mua i nā keikikāne (ʻo ia hoʻi, gonadarche). Inā hōʻike kāu keiki i kēia mau loli umauma a moekolohe paha i ka wā mua, me ka ulu ʻana o ka lauoho a me ke ʻala o ke kino, ʻaʻole paha ia he wā ʻōpiopio mua, akā he ʻano i kapa ʻia ʻo ka wā ʻōpiopio mua . He mea ʻokoʻa kēlā.

Pehea e ʻike ʻia ai ka Adrenarche mua?

Inā kānalua ʻia kāu keiki he mau hōʻailona o ka lawa ʻole o ka adrenal, e nānā mua kāu kauka pediatric inā he kumu ʻē aʻe no nā hōʻailona. Hiki i kekahi o kēia mau kūlana ke komo pū me:

• ʻŌpio mua
• ʻO ka hyperplasia adrenal congenital - He pilikia congenital kēia me ka hana ʻana o kekahi mau hormones i loko o nā kelepa adrenal.
• ʻO ka hōʻike ʻana o ka androgen exogenous - no ka laʻana, mai kekahi mau ʻano mea hoʻonani.
• Nā puʻupuʻu huna-androgen.

E hoʻokolokolo kino ʻia kāu keiki. I kēia manawa, makemake paha ke kauka e nānā i ka ʻāpana genital o ke keiki. Inā hana lākou, e loaʻa iā lākou ka ʻae mai iā ʻoe a me kāu keiki (ma muli o ko lākou mau makahiki). Hiki iā lākou ke paipai i nā mea e like me nā hoʻāʻo koko a me nā hoʻāʻo kiʻi.

I kekahi manawa, e kuhikuhi paha kāu pediatrician iā ʻoe i kahi endocrinologist pediatric, he loea i nā hormones. Ma hope wale nō o ka hana ʻia ʻana o kēia mau hoʻokolohua a pau a ʻaʻohe o nā kūlana koʻikoʻi i ʻōlelo ʻia ma luna nei e ʻike ʻia ai kāu keiki me ka adrenal insufficiency.

He mea nui e ʻike he 90% o nā hihia o ka lauoho pubic mua i nā keiki i hoʻokumu ʻia e kēia ʻano i kapa ʻia ʻo ka adrenal insufficiency. ʻO ke koena 10% i hoʻokumu ʻia e nā kūlana olakino ʻē aʻe i ʻōlelo ʻia ma luna.

He mea weliweli anei ka Adrenarche mua?

Ma ke ʻano he makua, he mea maʻamau ke hopohopo iki a makaʻu hoʻi ke ʻike mua ʻia ka lauoho o kāu keiki ma ka ʻaoʻao lima a me ka pubic ma mua o ka mea i manaʻo ʻia, a i ʻole ke hoʻomaka lākou e honi e like me ka hou. Eia nō naʻe, ʻaʻole ia he kūlana weliweli kino ka hemahema o ka adrenocortical premature.

Eia nō naʻe, ua hōʻike ʻia e ka noiʻi e hoʻonui iki paha kēia ʻano i ka pilikia o ka loaʻa ʻana o kekahi mau pilikia olakino i ka wā e hiki mai ana. ʻO kekahi o kēia mau pilikia:

• Momona
• Ke kū'ē ʻana o ka insulin - ʻO ia hoʻi, ʻaʻole pane pono nā cell o ke kino i ka insulin, hiki ke alakaʻi i kahi predisposition i ka maʻi diabetes.
• ʻO ka maʻi Polycystic ovary (PCOS) - He kūlana hormonal kēia i nā kaikamahine e hoʻoulu ai i nā cysts liʻiliʻi e hana ma nā ovaries.
• Nā maʻi naʻau - ʻo ia hoʻi, nā loli o ke ʻano, e like me ke kaumaha, ka hopohopo, a pēlā aku.

Ma waho aʻe o kēia mau pilikia kino, hiki i ka wā ʻōpiopio mua ke hoʻopilikia i ke olakino noʻonoʻo o ke keiki. E noʻonoʻo, i ka wā e ʻike ai ke keiki i nā loli mua i ko lākou kino, ʻaʻole like me nā keiki ʻē aʻe o ko lākou mau makahiki, hiki iā lākou ke hilahila, ʻoluʻolu ʻole, a manaʻo ʻokoʻa a ʻano ʻē. Hiki iā lākou ke hoʻohenehene ʻia e nā keiki ʻē aʻe (hoʻoweliweli) a loaʻa ka nānā ʻole ʻia mai nā poʻe ʻē aʻe. Inā ʻike ʻoe e kaumaha ana kāu keiki a hopohopo paha no kekahi mea e like me kēia, he manaʻo maikaʻi ke ʻimi i ka ʻōlelo aʻo mai kahi kanaka kūpono, e like me ke kauka noʻonoʻo keiki.

Aia kekahi lāʻau lapaʻau no ka adrenarche mua?

ʻAʻole. Ke hoʻomaka ka ulu ʻana o ka lauoho ma kahi pilikino a i ʻole nā ​​​​​​armpits, ʻaʻohe lāʻau lapaʻau e hiki ke hoʻōki a ulu hou paha.

ʻOiai aia kekahi mau lāʻau lapaʻau e hiki ke kōkua i ka kaohi ʻana i ke kaʻina hana hormonal i kahi kūlana i kapa ʻia ʻo precocious puberty, ʻaʻole pili kēia mau lāʻau lapaʻau i nā hormones e pili ana i nā kelepa adrenal.

Hiki ke pale ʻia ka Adrenarche ma mua o ka manawa?

ʻAʻole hiki ke pale ʻia kēia ma ke ʻano maʻamau. Eia nō naʻe, ua ʻike ʻia e ka noiʻi e hiki i kekahi mau kumu ke hoʻonui i ka pilikia o kahi keiki i ka loaʻa ʻana o ka lawa ʻole o ka adrenal. ʻO kekahi o kēia mau mea:

• ʻO ka hānau ʻia ʻana me ke kaumaha haʻahaʻa loa i ka wā hānau (ʻoi aku ke kaumaha ma mua o 2.5 kilokani, a i ʻole 5 paona 8 auneke, i ka wā hānau).
• Ka hānau mua ʻana (hānau ma mua o 37 mau pule o ka hāpai ʻana).
• Inā he moʻolelo o ka ʻeha o ka lolo, ʻo kēia ʻano ʻeha o ka lolo e hoʻonui pū i ka pilikia o ka wā ʻelemakule mua.

ʻO ka mea hope loa, nā mea e pono ai ke ʻike

Ma ke ʻano he mau mākua, he mea maʻamau ke hopohopo iki a me ke kaumaha ke ʻike ʻoe i kāu keiki e ulu mālie ana a hiki i ka wā ʻōpio, ʻoiai ke ʻike ʻoe i kēlā mau loli kino ma mua o ka mea i manaʻo ʻia.

Eia naʻe, ʻo ka mea nui e pono ai ʻoe e ʻike, ʻo ia ka adrenarche a me ka pubarche e hele pū ana me ia he mau hana kūlohelohe a maʻamau e hana ʻia i ke ola o kēlā me kēia keiki.

Hiki i ka adrenarche mua ke hopohopo, akā e hoʻomanaʻo, ʻaʻole ia e hōʻeha kino nui i ke keiki.

Inā he kānalua a nīnau paha kāu e pili ana i ka ulu ʻana o kāu keiki a i ʻole nā ​​loli i ko lākou kino, mai kānalua e nīnau i kāu kauka keiki. E hiki i ke kauka ke nānā i kāu keiki a wehewehe iā ʻoe inā e ulu olakino ana ʻo ia a e like me ka mea i manaʻo ʻia.

ʻAdrenarche , Adrenarche, DHEA, ʻŌpio, Pubarche, ʻŌpio Mua, ʻAdrenarche Mua, Ola Kino o ke Keiki, Nā Hormone, Ka Hoʻomohala ʻana o ke Keiki